International Journal of Neuropsychopharmacology
@ijnp.bsky.social
The official journal of
The International College of Neuropsychopharmacology (CINP)
https://linktr.ee/ijnp
The International College of Neuropsychopharmacology (CINP)
https://linktr.ee/ijnp
Opioid and Ketamine in the clinic: key methodological considerations
The question of whether ketamine’s antidepressant effects are mediated by glutamatergic plasticity or opioid receptor signalling remains a subject of considerable debate.
The question of whether ketamine’s antidepressant effects are mediated by glutamatergic plasticity or opioid receptor signalling remains a subject of considerable debate.
November 14, 2025 at 7:45 PM
Opioid and Ketamine in the clinic: key methodological considerations
The question of whether ketamine’s antidepressant effects are mediated by glutamatergic plasticity or opioid receptor signalling remains a subject of considerable debate.
The question of whether ketamine’s antidepressant effects are mediated by glutamatergic plasticity or opioid receptor signalling remains a subject of considerable debate.
🧠 Do dopamine D₂ partial agonists all bind the same way? Maybe not.
New evidence challenges the idea that all “third-generation” antipsychotics share a single D₂ receptor binding mode.
#Neuropsychopharmacology #Antipsychotics #Dopamine
New evidence challenges the idea that all “third-generation” antipsychotics share a single D₂ receptor binding mode.
#Neuropsychopharmacology #Antipsychotics #Dopamine
November 7, 2025 at 12:57 PM
🧠 Do dopamine D₂ partial agonists all bind the same way? Maybe not.
New evidence challenges the idea that all “third-generation” antipsychotics share a single D₂ receptor binding mode.
#Neuropsychopharmacology #Antipsychotics #Dopamine
New evidence challenges the idea that all “third-generation” antipsychotics share a single D₂ receptor binding mode.
#Neuropsychopharmacology #Antipsychotics #Dopamine
🧠 Hyperprolactinemia is usually seen as a side effect of antipsychotics — but could it be part of schizophrenia itself?
In first-episode, non- to minimally treated patients, there was a clear sex-specific endocrine disturbance.
In first-episode, non- to minimally treated patients, there was a clear sex-specific endocrine disturbance.
October 27, 2025 at 1:16 PM
🧠 Hyperprolactinemia is usually seen as a side effect of antipsychotics — but could it be part of schizophrenia itself?
In first-episode, non- to minimally treated patients, there was a clear sex-specific endocrine disturbance.
In first-episode, non- to minimally treated patients, there was a clear sex-specific endocrine disturbance.
🧠 Brain–Body in Postoperative Cognitive Dysfunction (POCD)
POCD is a common issue in older adults after surgery, causing memory loss + slower thinking
But what if the gut has something to do with it? 🦠
IJNP paper highlights how the gut–brain axis shapes recovery after surgery.
#GutBrainAxis
POCD is a common issue in older adults after surgery, causing memory loss + slower thinking
But what if the gut has something to do with it? 🦠
IJNP paper highlights how the gut–brain axis shapes recovery after surgery.
#GutBrainAxis
October 24, 2025 at 1:58 PM
🧠 Brain–Body in Postoperative Cognitive Dysfunction (POCD)
POCD is a common issue in older adults after surgery, causing memory loss + slower thinking
But what if the gut has something to do with it? 🦠
IJNP paper highlights how the gut–brain axis shapes recovery after surgery.
#GutBrainAxis
POCD is a common issue in older adults after surgery, causing memory loss + slower thinking
But what if the gut has something to do with it? 🦠
IJNP paper highlights how the gut–brain axis shapes recovery after surgery.
#GutBrainAxis
Duloxetine for Depression, how it is effectively targeting NET?
This is the first study to use PET imaging to track long-term NET occupancy, providing evidence on the SNRI mechanism without the influence of other medications.
This is the first study to use PET imaging to track long-term NET occupancy, providing evidence on the SNRI mechanism without the influence of other medications.
October 17, 2025 at 12:02 PM
Duloxetine for Depression, how it is effectively targeting NET?
This is the first study to use PET imaging to track long-term NET occupancy, providing evidence on the SNRI mechanism without the influence of other medications.
This is the first study to use PET imaging to track long-term NET occupancy, providing evidence on the SNRI mechanism without the influence of other medications.
In this month’s Editor’s Pick, Hashimoto et al. deliver an insightful meta-analysis comparing personality profiles in schizophrenia & bipolar disorder.
October 10, 2025 at 11:40 AM
In this month’s Editor’s Pick, Hashimoto et al. deliver an insightful meta-analysis comparing personality profiles in schizophrenia & bipolar disorder.
💊Lithium vs. Other Mood Stabilizers: Distinct Metabolic Signatures in #Bipolar Disorder (BP)
BD is primarily treated with mood stabilizers (MS): lithium represents the gold standard.
Despite its high clinical efficacy, the molecular players in treatment response remain partly unclear👇
#MedEd
BD is primarily treated with mood stabilizers (MS): lithium represents the gold standard.
Despite its high clinical efficacy, the molecular players in treatment response remain partly unclear👇
#MedEd
October 3, 2025 at 11:31 AM
New Study Alert: Anhedonia in MDD - Clinical Correlates & Treatment Response🧠
🚨New research published in IJNP confirms anhedonia (MADRS item 8 – inability to feel) as a key marker for severe MDD course.
🚨New research published in IJNP confirms anhedonia (MADRS item 8 – inability to feel) as a key marker for severe MDD course.
September 26, 2025 at 1:50 PM
New Study Alert: Anhedonia in MDD - Clinical Correlates & Treatment Response🧠
🚨New research published in IJNP confirms anhedonia (MADRS item 8 – inability to feel) as a key marker for severe MDD course.
🚨New research published in IJNP confirms anhedonia (MADRS item 8 – inability to feel) as a key marker for severe MDD course.
🚨Call for Symposia – CINP 2026, Glasgow🚨
Be part of shaping the scientific programme at one of Europe’s most vibrant cities!🌍✨
📅Deadline: 7th October 2025
💡30 symposia slots available – don’t miss this chance!
cinp2026.org/submissions/...
#cinp #neuropsychopharmacology
Be part of shaping the scientific programme at one of Europe’s most vibrant cities!🌍✨
📅Deadline: 7th October 2025
💡30 symposia slots available – don’t miss this chance!
cinp2026.org/submissions/...
#cinp #neuropsychopharmacology
Symposium Submission - Glasgow CINP2026
Symposia shall be of 75 minutes duration, and shall include three speakers, one of whom can, if desired, be the chairperson of the session.
cinp2026.org
September 23, 2025 at 9:49 AM
🚨Call for Symposia – CINP 2026, Glasgow🚨
Be part of shaping the scientific programme at one of Europe’s most vibrant cities!🌍✨
📅Deadline: 7th October 2025
💡30 symposia slots available – don’t miss this chance!
cinp2026.org/submissions/...
#cinp #neuropsychopharmacology
Be part of shaping the scientific programme at one of Europe’s most vibrant cities!🌍✨
📅Deadline: 7th October 2025
💡30 symposia slots available – don’t miss this chance!
cinp2026.org/submissions/...
#cinp #neuropsychopharmacology
📣Join CINP + BJPsych joint journal club to discuss the future of academic psychiatry with Prof Allan Young and experts!
September 19, 2025 at 7:02 PM
📣Join CINP + BJPsych joint journal club to discuss the future of academic psychiatry with Prof Allan Young and experts!
🧠🤖Affective states as clinical signals: AI models for decision-making and symptoms
This month’s Editor’s Pick examines the role of affective states in computational psychiatry—a field that uses mathematical and AI-based models to link behavior, brain function, and mental health.
This month’s Editor’s Pick examines the role of affective states in computational psychiatry—a field that uses mathematical and AI-based models to link behavior, brain function, and mental health.
September 19, 2025 at 6:32 PM
🧠🤖Affective states as clinical signals: AI models for decision-making and symptoms
This month’s Editor’s Pick examines the role of affective states in computational psychiatry—a field that uses mathematical and AI-based models to link behavior, brain function, and mental health.
This month’s Editor’s Pick examines the role of affective states in computational psychiatry—a field that uses mathematical and AI-based models to link behavior, brain function, and mental health.
📢Exciting news #CINP2026 in Glasgow will be a Joint Meeting of the Scandinavian College of Neuropsychopharmacology +the International College of Neuropsychopharmacology!
Join us for this unique event which promises to be an outstanding meeting of science &collaboration
@actaneuropsych.bsky.social
Join us for this unique event which promises to be an outstanding meeting of science &collaboration
@actaneuropsych.bsky.social
September 10, 2025 at 4:40 PM
📢Exciting news #CINP2026 in Glasgow will be a Joint Meeting of the Scandinavian College of Neuropsychopharmacology +the International College of Neuropsychopharmacology!
Join us for this unique event which promises to be an outstanding meeting of science &collaboration
@actaneuropsych.bsky.social
Join us for this unique event which promises to be an outstanding meeting of science &collaboration
@actaneuropsych.bsky.social
🧠🍷Neurogenesis, Ethanol & biomarker
It is known that excessive ethanol disrupts hippocampal structure/function, especially with adolescent onset. But how does neurogenesis plays out in this context?
It is known that excessive ethanol disrupts hippocampal structure/function, especially with adolescent onset. But how does neurogenesis plays out in this context?
September 5, 2025 at 1:09 PM
🧠🍷Neurogenesis, Ethanol & biomarker
It is known that excessive ethanol disrupts hippocampal structure/function, especially with adolescent onset. But how does neurogenesis plays out in this context?
It is known that excessive ethanol disrupts hippocampal structure/function, especially with adolescent onset. But how does neurogenesis plays out in this context?
⚡Beyond the Powerhouse: Mitochondria, Genes, and Depression in a Cross-Species Study
🧠🔋When mitochondrial function falters, the brain struggles to meet energy demands, contributing to the impaired plasticity observed in MDD.
#Mitochondria #Depression
🧠🔋When mitochondrial function falters, the brain struggles to meet energy demands, contributing to the impaired plasticity observed in MDD.
#Mitochondria #Depression
August 29, 2025 at 10:53 AM
⚡Beyond the Powerhouse: Mitochondria, Genes, and Depression in a Cross-Species Study
🧠🔋When mitochondrial function falters, the brain struggles to meet energy demands, contributing to the impaired plasticity observed in MDD.
#Mitochondria #Depression
🧠🔋When mitochondrial function falters, the brain struggles to meet energy demands, contributing to the impaired plasticity observed in MDD.
#Mitochondria #Depression
We are delighted to announce that the abstracts from CINP-AsCNP 2025 Joint Congress in Melbourne have been published as a Supplement to the International Journal of Neuropsychopharmacology
Read the abstracts here:
academic.oup.com/ijnp/issue/2...
Read the abstracts here:
academic.oup.com/ijnp/issue/2...
Volume 28 Issue Supplement_2 | International Journal of Neuropsychopharmacology | Oxford Academic
The official journal of Collegium Internationale Neuro-Psychopharmacologicum. Publishes papers that advance understanding of existing and new neuropsychopharmacological agents or provide insights into...
academic.oup.com
August 29, 2025 at 10:06 AM
We are delighted to announce that the abstracts from CINP-AsCNP 2025 Joint Congress in Melbourne have been published as a Supplement to the International Journal of Neuropsychopharmacology
Read the abstracts here:
academic.oup.com/ijnp/issue/2...
Read the abstracts here:
academic.oup.com/ijnp/issue/2...
Is it possible to predict antidepressant response?
📌 Check the Editor’s July Pick in #IJNP
This recent study investigated whether brain activity patterns (EEG) could help predict which patients with depression may respond to antidepressants (#vortioxetine or #escitalopram).
📌 Check the Editor’s July Pick in #IJNP
This recent study investigated whether brain activity patterns (EEG) could help predict which patients with depression may respond to antidepressants (#vortioxetine or #escitalopram).
August 26, 2025 at 8:20 PM
Is it possible to predict antidepressant response?
📌 Check the Editor’s July Pick in #IJNP
This recent study investigated whether brain activity patterns (EEG) could help predict which patients with depression may respond to antidepressants (#vortioxetine or #escitalopram).
📌 Check the Editor’s July Pick in #IJNP
This recent study investigated whether brain activity patterns (EEG) could help predict which patients with depression may respond to antidepressants (#vortioxetine or #escitalopram).
🔬 Personality Traits in Schizophrenia vs. Bipolar Disorder
Personality traits play pivotal roles in the onset, manifestation, and progression of schizophrenia (SCZ) and bipolar disorder (BD).
Personality traits play pivotal roles in the onset, manifestation, and progression of schizophrenia (SCZ) and bipolar disorder (BD).
August 15, 2025 at 7:58 PM
🔬 Personality Traits in Schizophrenia vs. Bipolar Disorder
Personality traits play pivotal roles in the onset, manifestation, and progression of schizophrenia (SCZ) and bipolar disorder (BD).
Personality traits play pivotal roles in the onset, manifestation, and progression of schizophrenia (SCZ) and bipolar disorder (BD).
🧠 More Than Mood: Anhedonia as a Public Health & Economic Issue
How one symptom can ripple through mental health, productivity, and the healthcare system.
In a large US study of ~75,000 adults (≥18 years) with depression, higher anhedonia was tied to:
How one symptom can ripple through mental health, productivity, and the healthcare system.
In a large US study of ~75,000 adults (≥18 years) with depression, higher anhedonia was tied to:
August 8, 2025 at 7:19 PM
🧠 More Than Mood: Anhedonia as a Public Health & Economic Issue
How one symptom can ripple through mental health, productivity, and the healthcare system.
In a large US study of ~75,000 adults (≥18 years) with depression, higher anhedonia was tied to:
How one symptom can ripple through mental health, productivity, and the healthcare system.
In a large US study of ~75,000 adults (≥18 years) with depression, higher anhedonia was tied to:
🧠 Over 100 types of RNA modifications exist, but N6-methyladenosine (m6A) is the most prevalent.
How are the modifications on neurotransmitters, plasticity and other mechanisms related to #Depression #Autism #Schizophrenia?
How are the modifications on neurotransmitters, plasticity and other mechanisms related to #Depression #Autism #Schizophrenia?
August 1, 2025 at 4:56 PM
🧠 Over 100 types of RNA modifications exist, but N6-methyladenosine (m6A) is the most prevalent.
How are the modifications on neurotransmitters, plasticity and other mechanisms related to #Depression #Autism #Schizophrenia?
How are the modifications on neurotransmitters, plasticity and other mechanisms related to #Depression #Autism #Schizophrenia?
🌍World Brain Day | 22 July - Brain Health for All Ages 🧠
As a journal dedicated to advancing neuropsychopharmacology, we join the global neuroscience community in recognizing World Brain Day
Understanding brain function in both health and disease is central to improving lives
As a journal dedicated to advancing neuropsychopharmacology, we join the global neuroscience community in recognizing World Brain Day
Understanding brain function in both health and disease is central to improving lives
July 22, 2025 at 10:00 PM
🌍World Brain Day | 22 July - Brain Health for All Ages 🧠
As a journal dedicated to advancing neuropsychopharmacology, we join the global neuroscience community in recognizing World Brain Day
Understanding brain function in both health and disease is central to improving lives
As a journal dedicated to advancing neuropsychopharmacology, we join the global neuroscience community in recognizing World Brain Day
Understanding brain function in both health and disease is central to improving lives
📢IJNP is pleased to welcome the new EiC, @wegener.bsky.social
IJNP continues to publish high-impact original articles, reviews, perspectives, and guidelines in basic and clinical neuropsychopharmacology.
IJNP continues to publish high-impact original articles, reviews, perspectives, and guidelines in basic and clinical neuropsychopharmacology.
July 4, 2025 at 8:42 PM
📢IJNP is pleased to welcome the new EiC, @wegener.bsky.social
IJNP continues to publish high-impact original articles, reviews, perspectives, and guidelines in basic and clinical neuropsychopharmacology.
IJNP continues to publish high-impact original articles, reviews, perspectives, and guidelines in basic and clinical neuropsychopharmacology.
📢 IJNP is pleased to welcome the new Editor-in-Chief, Prof. Gregers Wegener
On behalf of the CINP Executive Committee and the new editorial team, we extend our sincere gratitude to Prof Anthony Grace and the editorial board for their outstanding leadership and dedication over the years
On behalf of the CINP Executive Committee and the new editorial team, we extend our sincere gratitude to Prof Anthony Grace and the editorial board for their outstanding leadership and dedication over the years
July 1, 2025 at 4:44 PM
📢 IJNP is pleased to welcome the new Editor-in-Chief, Prof. Gregers Wegener
On behalf of the CINP Executive Committee and the new editorial team, we extend our sincere gratitude to Prof Anthony Grace and the editorial board for their outstanding leadership and dedication over the years
On behalf of the CINP Executive Committee and the new editorial team, we extend our sincere gratitude to Prof Anthony Grace and the editorial board for their outstanding leadership and dedication over the years
📢 We’re now on Social Media! 🧠🌐
The International Journal of Neuropsychopharmacology is expanding its presence across your favourite platforms.
Follow us to stay up to date with:
Cutting-edge research
Trending articles
Educational content
Calls for papers and special issue alerts
🔗 linktr.ee/ijnp
The International Journal of Neuropsychopharmacology is expanding its presence across your favourite platforms.
Follow us to stay up to date with:
Cutting-edge research
Trending articles
Educational content
Calls for papers and special issue alerts
🔗 linktr.ee/ijnp
June 3, 2025 at 1:00 PM
📢 We’re now on Social Media! 🧠🌐
The International Journal of Neuropsychopharmacology is expanding its presence across your favourite platforms.
Follow us to stay up to date with:
Cutting-edge research
Trending articles
Educational content
Calls for papers and special issue alerts
🔗 linktr.ee/ijnp
The International Journal of Neuropsychopharmacology is expanding its presence across your favourite platforms.
Follow us to stay up to date with:
Cutting-edge research
Trending articles
Educational content
Calls for papers and special issue alerts
🔗 linktr.ee/ijnp