IntFOLD
@intfold.bsky.social
Information about the IntFOLD server and its components. Predicted protein structures and functions from sequences. Follow for news on IntFOLD and its related methods - ModFOLD, ReFOLD, FunFOLD, MultiFOLD and ModFOLDdock.
Our paper on the performance of ModFOLDdock2 at #CASP16 onlinelibrary.wiley.com/doi/10.1002/...
Highlights of Model Quality Assessment in CASP16
Model quality assessment (MQA) remains a critical component of structural bioinformatics for both structure predictors and experimentalists seeking to use predictions for downstream applications. In ...
onlinelibrary.wiley.com
September 5, 2025 at 8:41 AM
Our paper on the performance of ModFOLDdock2 at #CASP16 onlinelibrary.wiley.com/doi/10.1002/...
We used IntFOLD, and MultiFOLD to model interactions between Cx62 and calpain-1: "Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62" | Haematologica haematologica.org/article/view...
Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62
| Haematologica
haematologica.org
August 5, 2025 at 8:41 AM
We used IntFOLD, and MultiFOLD to model interactions between Cx62 and calpain-1: "Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62" | Haematologica haematologica.org/article/view...
Our new paper has been published: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers url: academic.oup.com/nar/article/...
Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
Abstract. Understanding the structures of protein complexes is pivotal for breakthroughs in health, agriculture, bioengineering, and beyond. MultiFOLD2 and
academic.oup.com
July 9, 2025 at 8:37 AM
Our new paper has been published: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers url: academic.oup.com/nar/article/...
Our new paper is out: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...
Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
Abstract. Understanding the structures of protein complexes is pivotal for breakthroughs in health, agriculture, bioengineering, and beyond. MultiFOLD2 and
academic.oup.com
April 28, 2025 at 8:54 AM
Our new paper is out: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...
Reposted by IntFOLD
Pleased to share that our latest study has been published in Hematologica!
@rdgplateletlabs.bsky.social
pubmed.ncbi.nlm.nih.gov/40045892/
@rdgplateletlabs.bsky.social
pubmed.ncbi.nlm.nih.gov/40045892/
Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62 - PubMed
Connexin (Cx) gap junction proteins are expressed by a multitude of cells and function as plasma membrane hemichannels or dock to form intercellular communication tunnels. Whilst Cx43 has garnered con...
pubmed.ncbi.nlm.nih.gov
March 7, 2025 at 4:09 PM
Pleased to share that our latest study has been published in Hematologica!
@rdgplateletlabs.bsky.social
pubmed.ncbi.nlm.nih.gov/40045892/
@rdgplateletlabs.bsky.social
pubmed.ncbi.nlm.nih.gov/40045892/
Reposted by IntFOLD
Yesterday at #CASP16 I presented our new ModFOLDdock2 servers for the quality assessment of multimer models. It's great to see progress in the field but there are still many challenges ahead!
December 3, 2024 at 1:43 PM
Yesterday at #CASP16 I presented our new ModFOLDdock2 servers for the quality assessment of multimer models. It's great to see progress in the field but there are still many challenges ahead!
Reposted by IntFOLD
My group members, Shaima and @recep44.bsky.social, presented their posters on MultiFOLD2 for multimer modelling and FunFOLD5 for predicting protein-ligand interactions at #CASP16. Lots of interest and positive feedback!
December 3, 2024 at 1:47 PM
My group members, Shaima and @recep44.bsky.social, presented their posters on MultiFOLD2 for multimer modelling and FunFOLD5 for predicting protein-ligand interactions at #CASP16. Lots of interest and positive feedback!
Reposted by IntFOLD
ModFOLDdock2 is the top ranked method for predicting the interface accuracy of modelled protein complexes #CASP16. The server is available here: www.reading.ac.uk/bioinf/ModFO...
December 3, 2024 at 3:37 PM
ModFOLDdock2 is the top ranked method for predicting the interface accuracy of modelled protein complexes #CASP16. The server is available here: www.reading.ac.uk/bioinf/ModFO...
Reposted by IntFOLD
The ModFOLDdock2 server is now online and freely available to all. The ModFOLDdock2 variants ranked within the top few groups at #CASP16 in QMODE1/2 metrics. ModFOLDdock2 is the best method for predicting the interface accuracy of modelled protein complexes.
www.reading.ac.uk/bioinf/ModFO...
www.reading.ac.uk/bioinf/ModFO...
December 11, 2024 at 4:01 PM
The ModFOLDdock2 server is now online and freely available to all. The ModFOLDdock2 variants ranked within the top few groups at #CASP16 in QMODE1/2 metrics. ModFOLDdock2 is the best method for predicting the interface accuracy of modelled protein complexes.
www.reading.ac.uk/bioinf/ModFO...
www.reading.ac.uk/bioinf/ModFO...
Reposted by IntFOLD
Our MultiFOLD2 server is also now freely available to all. It's the top-ranked server on the hardest domain targets in #CASP16 by GDT_TS. With integrated stoichiometry prediction it outperforms AF3 on common multimer subsets in CAMEO. www.reading.ac.uk/bioinf/Multi...
December 12, 2024 at 4:55 PM
Our MultiFOLD2 server is also now freely available to all. It's the top-ranked server on the hardest domain targets in #CASP16 by GDT_TS. With integrated stoichiometry prediction it outperforms AF3 on common multimer subsets in CAMEO. www.reading.ac.uk/bioinf/Multi...