IntFOLD
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intfold.bsky.social
IntFOLD
@intfold.bsky.social
Information about the IntFOLD server and its components. Predicted protein structures and functions from sequences. Follow for news on IntFOLD and its related methods - ModFOLD, ReFOLD, FunFOLD, MultiFOLD and ModFOLDdock.
Pinned
The main link for IntFOLD server:

reading.ac.uk/bioinf/IntFO...
Bioinformatics Web Servers - University of Reading
reading.ac.uk
We used IntFOLD, and MultiFOLD to model interactions between Cx62 and calpain-1: "Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62" | Haematologica haematologica.org/article/view...
Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62 | Haematologica
haematologica.org
August 5, 2025 at 8:41 AM
Our new paper has been published: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers url: academic.oup.com/nar/article/...
Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
Abstract. Understanding the structures of protein complexes is pivotal for breakthroughs in health, agriculture, bioengineering, and beyond. MultiFOLD2 and
academic.oup.com
July 9, 2025 at 8:37 AM
Our new paper is out: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
academic.oup.com/nar/advance-...
Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
Abstract. Understanding the structures of protein complexes is pivotal for breakthroughs in health, agriculture, bioengineering, and beyond. MultiFOLD2 and
academic.oup.com
April 28, 2025 at 8:54 AM
The main link for IntFOLD server:

reading.ac.uk/bioinf/IntFO...
Bioinformatics Web Servers - University of Reading
reading.ac.uk
February 18, 2025 at 1:48 PM
Reposted by IntFOLD
Yesterday at #CASP16 I presented our new ModFOLDdock2 servers for the quality assessment of multimer models. It's great to see progress in the field but there are still many challenges ahead!
December 3, 2024 at 1:43 PM
Reposted by IntFOLD
My group members, Shaima and @recep44.bsky.social, presented their posters on MultiFOLD2 for multimer modelling and FunFOLD5 for predicting protein-ligand interactions at #CASP16. Lots of interest and positive feedback!
December 3, 2024 at 1:47 PM
Reposted by IntFOLD
ModFOLDdock2 is the top ranked method for predicting the interface accuracy of modelled protein complexes #CASP16. The server is available here: www.reading.ac.uk/bioinf/ModFO...
December 3, 2024 at 3:37 PM
Reposted by IntFOLD
The ModFOLDdock2 server is now online and freely available to all. The ModFOLDdock2 variants ranked within the top few groups at #CASP16 in QMODE1/2 metrics. ModFOLDdock2 is the best method for predicting the interface accuracy of modelled protein complexes.
www.reading.ac.uk/bioinf/ModFO...
December 11, 2024 at 4:01 PM
Reposted by IntFOLD
Our MultiFOLD2 server is also now freely available to all. It's the top-ranked server on the hardest domain targets in #CASP16 by GDT_TS. With integrated stoichiometry prediction it outperforms AF3 on common multimer subsets in CAMEO. www.reading.ac.uk/bioinf/Multi...
December 12, 2024 at 4:55 PM