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IorioLab @ioriolab.bsky.social · 1d

Kudos to Yasin Ilkagan Tepeli for defending his PhD at TU Delft (June 2025)! During his PhD at goncalveslab.tudelft.nl, he visited our lab working on Oncostratifier for oncogene-addicted cohort stratification and therapeutic target prediction.

Computational Molecular Biomedicine

in Computer Science Tecnical University of Lisbon

goncalveslab.tudelft.nl

IorioLab @ioriolab.bsky.social · 25d

Francesco will be speaking at the High-Content CRISPR Screening conference, taking place March 18–19, 2026 in Vienna 🇦🇹 alongside leading experts in CRISPR screening, functional genomics, and drug discovery
www.linkedin.com/posts/myllia...

The registration and abstract submission for the "High-Content CRISPR Screening" conference on March 18–19, 2026, in Vienna, Austria is now open! Secure your spot via the conference website...

The registration and abstract submission for the "High-Content CRISPR Screening" conference on March 18–19, 2026, in Vienna, Austria is now open! Secure your spot via the conference website: https://...

www.linkedin.com

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IorioLab @ioriolab.bsky.social · 29d

🚨 We’re hiring! 🚨 looking for a computational postdoc to lead an exciting project at the intersection of AI, CRISPR, multi-omics, and cancer genomics.
Join us to design the next generation of genetic interaction screens and uncover new synthetic lethalities
www.linkedin.com/jobs/view/42...

Human Technopole hiring Postdoc in Cancer Synthetic Lethality Prediction and AI-Driven Target Discovery in Milan, Lombardy, Italy | LinkedIn

Posted 2:37:53 PM. APPLICATION CLOSING DATE: October 12, 2025Human Technopole (HT) is an interdisciplinary life…See this and similar jobs on LinkedIn.

www.linkedin.com

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IorioLab @ioriolab.bsky.social · Sep 11

Today we bid farewell to our postDoc @aurorasavino.bsky.social, who is moving to an independent position at the University of Torino. Her talent dedication and collaborative spirit have left a lasting mark on our team and projects🎉
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾

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Francesco Iorio @francescoiorio.bsky.social · Jul 25

Just back from the GRC on Synthetic Lethality in Oncology: great science, deep discussion, great venue and flawless organisation. Thanks to @mgarnett.bsky.social, Benjamin Schwartz & @vazquezf.bsky.social for leading a fantastic meeting at the frontier of cancer research #SyntheticLethality #GRC

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ianoverton.bsky.social @ianoverton.bsky.social · Jul 24

Enjoying the Gordon Conference on Synthetic Lethality in Oncology with @francescoiorio.bsky.social and @maxbillmann.bsky.social 😊 #bioinformatics #gordonConference #syntheticLethality

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Francesco Iorio @francescoiorio.bsky.social · Jul 18

happy and honoured to have had a chance to deliver a lecture @bocconi.bsky.social University on AIapplications in life sciences and to share exciting projects we are developing at @humantechnopole.bsky.social-
A great opportunity to engage with a community that values innovation and forwardThinking

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IorioLab @ioriolab.bsky.social · Jul 6

@humantechnopole.bsky.social, with old friends and colleagues @emanuelvgo.bsky.social @colmr.bsky.social Lodewyk Wessels

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IorioLab @ioriolab.bsky.social · Jul 6

New work out in @natgenet.nature.com from @davidjadams.bsky.social Lab @sangerinstitute.bsky.social (with a contribution from us led by A.Vinceti): CDS2 is a cancer dependency in uveal melanomas with low CDS1 expression: a synthetic lethal axis with broad potential
🔗 www.nature.com/articles/s41...

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types - Nature Genetics

This study employs a functional genomic approach to identify a synthetic lethal interaction between CDS1 and CDS2 in uveal melanoma and other cancers, which may represent a potential therapeutic targe...

www.nature.com

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Francesco Iorio @francescoiorio.bsky.social · Jun 19

Proud to announce that the 2nd European Cancer DepMap Symposium has the patronage of AIRC: the Italian Association for Cancer Research. Honoured by their support as we bring together leading scientists on cancer-dependencies functional-genomics CRISPR
🔗 humantechnopole.it/en/trainings...
#EuroDepMap

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IorioLab @ioriolab.bsky.social · Jun 18

we are at #EACR2025 with two posters - the second one is presented by Ludovica Proietti and Gianluca vozza and focuses on our ERC funded DEPshock project
@humantechnopole.bsky.social

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IorioLab @ioriolab.bsky.social · Jun 18

we are at #EACR2025 with two posters, one presented by our Ottavio Croci on our collaborative work around a CRISPR based prioritisation of lncRNA vulnerabilities in multiple myeloma @humantechnopole.bsky.social

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IorioLab @ioriolab.bsky.social · Jun 12

Big thanks to @floriangrebien.bsky.social for a fantastic seminar yesterday at @humantechnopole.bsky.social 🔬🧬 a masterclass in dissecting AML vulnerabilities with precision and creativity. We loved the science and the lunch chat too! 👏 #cancerbiology #AML #condensates

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IorioLab @ioriolab.bsky.social · Jun 12

Big thanks to @floriangrebien.bsky.social for a fantastic seminar yesterday at @humantechnopole.bsky.social 🔬🧬 a masterclass in dissecting AML vulnerabilities with precision and creativity. We loved the science and the lunch chat too! 👏 #cancerbiology #AML #condensates

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IorioLab @ioriolab.bsky.social · Jun 11

🧬 Excited to announce the 2nd Euro Cancer DepMap Symposium bringing together leading minds in functional genomics, cancer vulnerabilities, AI, CRISPR and anti-cancer target discovery.📍Join us in Milan for cutting-edge science, open discussion & collaboration. #EuroDepMap #CancerResearch #CRISPR

Human Technopole @humantechnopole.bsky.social · Jun 11

🔬 Join us in Milan for the 2nd European Cancer Dependency Map Symposium #ECDM25! A key event for scientists in functional genomics & target discovery. Talks, panels, AI & poster sessions await.

Register now 👉 humantechnopole.it/en/trainings...

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IorioLab @ioriolab.bsky.social · Dec 12

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IorioLab @ioriolab.bsky.social · Dec 12

🎄🎁 Secret Santa at IorioLab! 🎁🎄
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas

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IorioLab @ioriolab.bsky.social · Dec 10

Amazing Bavarian-style @humantechnopole.bsky.social CompBiol Centre Xmas Dinner w @bioimagecomputing.com @sottoriva.bsky.social and other labs 🍺🎄👍💻🧬

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Emanuel Gonçalves @emanuelvgo.bsky.social · Nov 29

Thrilled to share our first dive into generative models, integrating 7 distinct omics to generate a complete Synthetic Cancer Dependency Map for +1,500 cancer cell lines! Excited for what’s ahead. rdcu.be/d1TgQ #GarnettLab #CMRI #ProCan #INESC-ID #IST @naturecomms.bsky.social

Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning

Nature Communications - Multi-omics integration is often limited by data sparsity and heterogeneity. Here, the authors develop MOSA, a method designed to augment DepMap cell line data to...

rdcu.be

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IorioLab @ioriolab.bsky.social · Nov 28

🎓 Huge congratulations to Irene FernandezRebollo
and @alessandrodigilio.bsky.social on graduating and successfully defending their master theses on cancer-specific epigenetic clocks! 🧬🕒 Wishing you both great success in your next adventures @manelesteller.bsky.social @humantechnopole.bsky.social

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IorioLab @ioriolab.bsky.social · Nov 26

It has been great to be involved in this collaborative project linking ADD3 to cell morphology and vulnerabilities of glioblastoma, using data from the @depmap.org and computational analyses led by our Raffaele Iannuzzi @humantechnopole.bsky.social

Human Technopole @humantechnopole.bsky.social · Nov 26

🔬Our Kalebic group with our @francescoiorio.bsky.social Group identified ADD3 as a key gene driving glioblastoma stem cell shape and tumour connectivity, uncovering growth and therapy resistance

📰Published in Life Science Alliance with support from AIRC

humantechnopole.it/en/news/canc...

Cancer stem cell morphology predicts glioblastoma growth and resistance - Human Technopole

Human Technopole researchers have identified adducin-γ (ADD3) as a crucial regulator of glioblastoma cancer stem cell morphology and intercellular bridges between tumour cells. These connections facil...

humantechnopole.it

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Jon Lim, MRCP PhD @drjonlim.bsky.social · Nov 23

🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov

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IorioLab @ioriolab.bsky.social · Nov 22

Kudos to our Flavio Passante for presenting his work on new computational approaches for #drug_repurposing within the NEUROCOV-eu consortium @humantechnopole.bsky.social at the SEMM PhD-student Retreat 2024 and for winning the best poster prize award 🥳🥳

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