IorioLab
@ioriolab.bsky.social
350 followers
360 following
16 posts
we mix informatics/biology/functional-genomics to identify new therapeutic targets/markers, for cancer and other human diseases. we ❤️ CRISPR, statistics and ML
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Reposted by IorioLab
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IorioLab
@ioriolab.bsky.social
· Jul 6
IorioLab
@ioriolab.bsky.social
· Jul 6
The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types - Nature Genetics
This study employs a functional genomic approach to identify a synthetic lethal interaction between CDS1 and CDS2 in uveal melanoma and other cancers, which may represent a potential therapeutic targe...
www.nature.com
Reposted by IorioLab
Reposted by IorioLab
Reposted by IorioLab
Emanuel Gonçalves
@emanuelvgo.bsky.social
· Nov 29
Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning
Nature Communications - Multi-omics integration is often limited by data sparsity and heterogeneity. Here, the authors develop MOSA, a method designed to augment DepMap cell line data to...
rdcu.be
IorioLab
@ioriolab.bsky.social
· Nov 26
Reposted by IorioLab