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Reposted by Francesco Iorio

Open Targets @opentargets.org · 7d

CLOSING: Postdoc in @francescoiorio.bsky.social's lab at @humantechnopole.bsky.social

Apply through LinkedIn by 5 October: www.linkedin.com/jobs/view/43...

#scienceJobs #AcademicSky #postdocJobs

Closing job ad for a postdoc in CRISPR meta-analytics and AI, from Open Targets and the Human Technopole. The role is in the Iorio Lab, salary up to 40k euros, apply by 5 October.

The description reads: The Perturbation Catalogue project aims to create an online repository of data from post-perturbational experiments. You will focus on a meta-analytics project, developing computational methods for the reproducibility assessment, harmonisation and analysis or inter-study CRISPR datasets, aggregating data and developing and using innovative AI-based methods for therapeutic target prioritisation pipelines.

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Reposted by Francesco Iorio

Evangelia Petsalaki @epetsalaki.bsky.social · 23d

Join us for this exciting meeting!

Francesco Iorio @francescoiorio.bsky.social · 23d

📢 The 2nd European Cancer Dependency Map Symposium is coming!
🗓️ 20 Nov 2025
📍 Human Technopole, Milan
Join us for a one-day dive into:
🔹 Cancer genomics
🔹 CRISPR screening
🔹 AI-driven target discovery
With the patronage of AIRC
🔗 humantechnopole.it/en/trainings...

2nd European Cancer Dependency Map Symposium - Human Technopole

The 2nd European Cancer Dependency Map Symposium is a scientific event open to the national and international scientific community working in computational genomics, pharmacogenomics, and therapeutic ...

humantechnopole.it

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Francesco Iorio @francescoiorio.bsky.social · 23d

📢 The 2nd European Cancer Dependency Map Symposium is coming!
🗓️ 20 Nov 2025
📍 Human Technopole, Milan
Join us for a one-day dive into:
🔹 Cancer genomics
🔹 CRISPR screening
🔹 AI-driven target discovery
With the patronage of AIRC
🔗 humantechnopole.it/en/trainings...

2nd European Cancer Dependency Map Symposium - Human Technopole

The 2nd European Cancer Dependency Map Symposium is a scientific event open to the national and international scientific community working in computational genomics, pharmacogenomics, and therapeutic ...

humantechnopole.it

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Reposted by Francesco Iorio

IorioLab @ioriolab.bsky.social · 24d

Francesco will be speaking at the High-Content CRISPR Screening conference, taking place March 18–19, 2026 in Vienna 🇦🇹 alongside leading experts in CRISPR screening, functional genomics, and drug discovery
www.linkedin.com/posts/myllia...

The registration and abstract submission for the "High-Content CRISPR Screening" conference on March 18–19, 2026, in Vienna, Austria is now open! Secure your spot via the conference website...

The registration and abstract submission for the "High-Content CRISPR Screening" conference on March 18–19, 2026, in Vienna, Austria is now open! Secure your spot via the conference website: https://...

www.linkedin.com

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Francesco Iorio @francescoiorio.bsky.social · 28d

10 September 2025

Francesco Iorio @francescoiorio.bsky.social · 28d

Join Us! @ioriolab.bsky.social

IorioLab @ioriolab.bsky.social · 28d

🚨 We’re hiring! 🚨 looking for a computational postdoc to lead an exciting project at the intersection of AI, CRISPR, multi-omics, and cancer genomics.
Join us to design the next generation of genetic interaction screens and uncover new synthetic lethalities
www.linkedin.com/jobs/view/42...

Human Technopole hiring Postdoc in Cancer Synthetic Lethality Prediction and AI-Driven Target Discovery in Milan, Lombardy, Italy | LinkedIn

Posted 2:37:53 PM. APPLICATION CLOSING DATE: October 12, 2025Human Technopole (HT) is an interdisciplinary life…See this and similar jobs on LinkedIn.

www.linkedin.com

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Reposted by Francesco Iorio

IorioLab @ioriolab.bsky.social · 29d

Today we bid farewell to our postDoc @aurorasavino.bsky.social, who is moving to an independent position at the University of Torino. Her talent dedication and collaborative spirit have left a lasting mark on our team and projects🎉
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾

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Francesco Iorio @francescoiorio.bsky.social · Aug 30

Excited to share that I’ve joined the Scientific Advisory Board of #DrugReKindle, a startup harnessing AI and computational biology to advance drug repurposing across human diseases.
Grateful to the team for the opportunity. Looking forward to the journey ahead.

www.linkedin.com/posts/drugre...

#drugrekindle #drugrepurposing #aiinbiotech #smarterdrugdiscovery #healthinnovation #precisionmedicine #translationalscience #repurposetoadvance | DrugReKindle

🔄 Drug Repurposing: A Smarter Way to Unlock Therapeutic Value The current model of drug development is expensive, risky, and painfully slow. Bringing a new drug to market takes 10–15 years and over $2...

www.linkedin.com

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Francesco Iorio @francescoiorio.bsky.social · Jul 25

Just back from the GRC on Synthetic Lethality in Oncology: great science, deep discussion, great venue and flawless organisation. Thanks to @mgarnett.bsky.social, Benjamin Schwartz & @vazquezf.bsky.social for leading a fantastic meeting at the frontier of cancer research #SyntheticLethality #GRC

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Reposted by Francesco Iorio

ianoverton.bsky.social @ianoverton.bsky.social · Jul 24

Enjoying the Gordon Conference on Synthetic Lethality in Oncology with @francescoiorio.bsky.social and @maxbillmann.bsky.social 😊 #bioinformatics #gordonConference #syntheticLethality

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Francesco Iorio @francescoiorio.bsky.social · Jul 18

happy and honoured to have had a chance to deliver a lecture @bocconi.bsky.social University on AIapplications in life sciences and to share exciting projects we are developing at @humantechnopole.bsky.social-
A great opportunity to engage with a community that values innovation and forwardThinking

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Francesco Iorio @francescoiorio.bsky.social · Jul 6

great work from @davidjadams.bsky.social out now in @natgenet.nature.com (with a computational contribution from the @ioriolab.bsky.social @humantechnopole.bsky.social led by A.Vinceti)

IorioLab @ioriolab.bsky.social · Jul 6

New work out in @natgenet.nature.com from @davidjadams.bsky.social Lab @sangerinstitute.bsky.social (with a contribution from us led by A.Vinceti): CDS2 is a cancer dependency in uveal melanomas with low CDS1 expression: a synthetic lethal axis with broad potential
🔗 www.nature.com/articles/s41...

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types - Nature Genetics

This study employs a functional genomic approach to identify a synthetic lethal interaction between CDS1 and CDS2 in uveal melanoma and other cancers, which may represent a potential therapeutic targe...

www.nature.com

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Francesco Iorio @francescoiorio.bsky.social · Jun 19

Proud to announce that the 2nd European Cancer DepMap Symposium has the patronage of AIRC: the Italian Association for Cancer Research. Honoured by their support as we bring together leading scientists on cancer-dependencies functional-genomics CRISPR
🔗 humantechnopole.it/en/trainings...
#EuroDepMap

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Reposted by Francesco Iorio

IorioLab @ioriolab.bsky.social · Jun 18

we are at #EACR2025 with two posters - the second one is presented by Ludovica Proietti and Gianluca vozza and focuses on our ERC funded DEPshock project
@humantechnopole.bsky.social

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Reposted by Francesco Iorio

IorioLab @ioriolab.bsky.social · Jun 18

we are at #EACR2025 with two posters, one presented by our Ottavio Croci on our collaborative work around a CRISPR based prioritisation of lncRNA vulnerabilities in multiple myeloma @humantechnopole.bsky.social

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Francesco Iorio @francescoiorio.bsky.social · Jun 17

Cingratulations @diegodibi.bsky.social !! Well deserved 💪

di Bernardo Lab @diegodibi.bsky.social · Jun 17

I got an ERC Advanced Grant :))))) www.eurekalert.org/news-release...

ERC awards €2.5 million to TIGEM scientist for project on programmable genetic circuits

Diego Di Bernardo of the Telethon Institute of Genetics and Medicine (TIGEM) has received a €2.5 million ERC Advanced Grant for DIMERCIRCUITS, a project that combines synthetic biology, artificia...

www.eurekalert.org

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Francesco Iorio @francescoiorio.bsky.social · Jun 11

Following the success of the first European Cancer Dependency Map Symposium in 2023, we are excited to announce the 2nd edition, to be held at Human Technopole on the 20th November 2025. Registration and Poster submission now open!
humantechnopole.it/en/trainings...
youtu.be/x2erCuovGvc
#EuroDepMap

1st European Cancer Dependency Map Symposium

YouTube video by Human Technopole

youtu.be

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Francesco Iorio @francescoiorio.bsky.social · Jun 11

🧬 Excited to announce the 2nd Euro Cancer DepMap Symposium bringing together leading minds in functional genomics, cancer vulnerabilities, AI, CRISPR and anti-cancer target discovery.📍Join us in Milan for cutting-edge science, open discussion & collaboration. #EuroDepMap #CancerResearch #CRISPR

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Reposted by Francesco Iorio

di Bernardo Lab @diegodibi.bsky.social · Apr 28

www.sciencedirect.com/science/arti... Just found out that our work on computational drug repositioning (mantra.tigem.it) among the 20 most cited articles worldwide in Scopus that are part of the collection. @francescoiorio.bsky.social

A bibliometric review on in silico drug repurposing: Performance analysis, science mapping and text mining (2000–2023)

Drug repositioning is a technique to investigate whether a drug already approved for one disease will function for another disease not included in the…

www.sciencedirect.com

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Reposted by Francesco Iorio

Human Technopole @humantechnopole.bsky.social · Feb 12

🤩 The February issue of @naturemethods.bsky.social features on its cover the research of our Giuseppe Testa Group on mosaic organoids to study the brains of multiple patients simultaneously.

Read more about the research 👉 humantechnopole.it/en/news/mosa...

Nature Methods @natmethods.nature.com · Feb 11

Our February issue is live! 🎉
nature.com/nmeth/volume...

On the cover, a human brain emerges from multiple stem cell lineages, representing a method to link genetic variation to neurodevelopmental trajectories.

Paper here: nature.com/articles/s41...

Image by Philipp Dexheimer.

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Reposted by Francesco Iorio

Emanuel Gonçalves @emanuelvgo.bsky.social · Feb 7

The submission deadline has been extended to *8 May 2025*!
"Genome Biology is calling for submissions to our Collection on key genetic determinants and functional consequences of genome editing interventions in the context of cancer."
#CRISPR www.biomedcentral.com/collections/...

Call for papers - Genome editing and cancer

www.biomedcentral.com

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Reposted by Francesco Iorio

European Research Council (ERC) @erc.europa.eu · Feb 7

Hello, Bluesky! ☀️

We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.

Follow us for updates on ERC funding, research policy, and our grantees' discoveries.

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Reposted by Francesco Iorio

Francisca Vazquez PhD @vazquezf.bsky.social · Feb 6

(1/3) Excited to share our latest work using
@depmap.org to uncover a new synthetic lethality in two distinct patient populations!

We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO

#CancerResearch #SyntheticLethality #Genomics #DepMap

SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO - Nature

Analysis of large-scale CRISPR screening data, combined with experiments in patient-derived tumour organoid models, identifies PELO as a potential therapeutic target in chromosomal 9p21.3-deleted canc...

nature.com

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Francesco Iorio @francescoiorio.bsky.social · Feb 3

Great and inspiring talk today at @humantechnopole.bsky.social delivered by Giorgio Galli from Novartis

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Damian Dalle Nogare @damiandn.bsky.social · Feb 2

Probably a good time to remind my American friends that my institute here in Milan is recruiting broadly for everything from the postdoc to group leader level, and we have visa and immigration support 🇪🇺.

Careers homepage

careers.humantechnopole.it

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