Gene Doctor Gene
@isog.bsky.social
Gene Levinson, Ph.D. | Evolutionary Theorist
Research: Updated Evolutionary Synthesis framework
Founder, CognitoSymbiosis LLC (Research)
cognitosymbiosis.com
#Evolution #Science #Research
🧪📚🙏
Research: Updated Evolutionary Synthesis framework
Founder, CognitoSymbiosis LLC (Research)
cognitosymbiosis.com
#Evolution #Science #Research
🧪📚🙏
Pinned
SARS‑CoV‑2 (COVID-19) in SARS‑CoV‑2 (COVID-19)
Good news
The first vaccine designed to target the entire SARS virus family, GBP511, has entered human clinical trials.
Developed by UW Medicine and brought to trial by SK Bioscience, it aims to p...
open.substack.com
🧪🙏Good news- the first #vaccine targeting the entire SARS family - not just covid-19- has entered human clinical trials —
open.substack.com/chat/posts/a...
open.substack.com/chat/posts/a...
🧪 Epigenetic inheritance of acquired traits via stem cells dedifferentiation/differentiation or transdifferentiation cycles by Arshak Alexanian
thenode.biologists.com/epigenetic-i...
thenode.biologists.com/epigenetic-i...
Epigenetic inheritance of acquired traits via stem cells dedifferentiation/differentiation or transdifferentiation cycles - the Node
Do cells carry memories of the whole body into the next generation? For more than two millennia, biologists and philosophers have debated whether traits
thenode.biologists.com
February 10, 2026 at 12:12 PM
🧪 Epigenetic inheritance of acquired traits via stem cells dedifferentiation/differentiation or transdifferentiation cycles by Arshak Alexanian
thenode.biologists.com/epigenetic-i...
thenode.biologists.com/epigenetic-i...
Reposted by Gene Doctor Gene
Phenomenal #SuperBowl halftime show from Bad Bunny.
February 9, 2026 at 1:35 AM
Phenomenal #SuperBowl halftime show from Bad Bunny.
Read “Steve Jobs Made 12 Predictions in 1990. They Just Came True.“ by Shane Collins on Medium: medium.com/activated-th...
Steve Jobs Made 12 Predictions in 1990. They Just Came True.
The “Lost Interview” wasn’t about computers. It was a blueprint for the AI era and the death of traditional management.
medium.com
February 4, 2026 at 4:20 PM
Read “Steve Jobs Made 12 Predictions in 1990. They Just Came True.“ by Shane Collins on Medium: medium.com/activated-th...
🧪🙏 Loss of hunger hormone may be key to snakes’ mastery of fasting
click.aaas.sciencepubs.org?qs=eyJkZWtJZ...
click.aaas.sciencepubs.org?qs=eyJkZWtJZ...
February 4, 2026 at 2:40 PM
🧪🙏 Loss of hunger hormone may be key to snakes’ mastery of fasting
click.aaas.sciencepubs.org?qs=eyJkZWtJZ...
click.aaas.sciencepubs.org?qs=eyJkZWtJZ...
🧪🙏Good news- the first #vaccine targeting the entire SARS family - not just covid-19- has entered human clinical trials —
open.substack.com/chat/posts/a...
open.substack.com/chat/posts/a...
SARS‑CoV‑2 (COVID-19) in SARS‑CoV‑2 (COVID-19)
Good news
The first vaccine designed to target the entire SARS virus family, GBP511, has entered human clinical trials.
Developed by UW Medicine and brought to trial by SK Bioscience, it aims to p...
open.substack.com
February 4, 2026 at 1:33 PM
🧪🙏Good news- the first #vaccine targeting the entire SARS family - not just covid-19- has entered human clinical trials —
open.substack.com/chat/posts/a...
open.substack.com/chat/posts/a...
Reposted by Gene Doctor Gene
The new Canada Groceries and Essentials Benefit will put hundreds of dollars more into the bank accounts of over twelve million Canadians.
January 27, 2026 at 3:13 PM
The new Canada Groceries and Essentials Benefit will put hundreds of dollars more into the bank accounts of over twelve million Canadians.
Reposted by Gene Doctor Gene
E.P.A. to Stop Considering Lives Saved When Setting Rules on Air Pollution www.nytimes.com/2026/01/12/c...
E.P.A. to Stop Considering Lives Saved When Setting Rules on Air Pollution
www.nytimes.com
January 16, 2026 at 4:09 PM
E.P.A. to Stop Considering Lives Saved When Setting Rules on Air Pollution www.nytimes.com/2026/01/12/c...
BREAKING: Trump approval drops 42 percent from January to December
Trump’s net approval rating fell by a stunning 42 points from January to December, a drop so severe that Enten compared the president to a deep sea dive. rawstory.substack.com/p/breaking-t...
Trump’s net approval rating fell by a stunning 42 points from January to December, a drop so severe that Enten compared the president to a deep sea dive. rawstory.substack.com/p/breaking-t...
BREAKING: Trump approval drops 42 percent from January to December
Trump’s net approval rating fell by a stunning 42 points from January to December, a drop so severe that Enten compared the president to a deep sea dive.
Share this widely so everyone knows how far T...
rawstory.substack.com
January 16, 2026 at 4:02 PM
BREAKING: Trump approval drops 42 percent from January to December
Trump’s net approval rating fell by a stunning 42 points from January to December, a drop so severe that Enten compared the president to a deep sea dive. rawstory.substack.com/p/breaking-t...
Trump’s net approval rating fell by a stunning 42 points from January to December, a drop so severe that Enten compared the president to a deep sea dive. rawstory.substack.com/p/breaking-t...
Reposted by Gene Doctor Gene
Something not political!!
I am so excited to go welcome the monks during their Walk for Peace tomorrow! They will be walking right near my house, on the way to Charlotte.
Texas to Washington DC. What amazing dedication, just trying to spread some peace and love in this insane world 🙏☮️
I am so excited to go welcome the monks during their Walk for Peace tomorrow! They will be walking right near my house, on the way to Charlotte.
Texas to Washington DC. What amazing dedication, just trying to spread some peace and love in this insane world 🙏☮️
January 14, 2026 at 2:52 AM
Something not political!!
I am so excited to go welcome the monks during their Walk for Peace tomorrow! They will be walking right near my house, on the way to Charlotte.
Texas to Washington DC. What amazing dedication, just trying to spread some peace and love in this insane world 🙏☮️
I am so excited to go welcome the monks during their Walk for Peace tomorrow! They will be walking right near my house, on the way to Charlotte.
Texas to Washington DC. What amazing dedication, just trying to spread some peace and love in this insane world 🙏☮️
This Ted talk is excellent- 15 million views and counting Author of “The Power of Meaning” , Emily Esfahani Smith 🧪📚🙏🌏
www.ted.com/talks/emily_...
www.ted.com/talks/emily_...
There's more to life than being happy
Our culture is obsessed with happiness, but what if there's a more fulfilling path? Happiness comes and goes, says writer Emily Esfahani Smith, but having meaning in life -- serving something beyond y...
www.ted.com
January 14, 2026 at 5:25 PM
This Ted talk is excellent- 15 million views and counting Author of “The Power of Meaning” , Emily Esfahani Smith 🧪📚🙏🌏
www.ted.com/talks/emily_...
www.ted.com/talks/emily_...
🧪
Our paper on the newest version of the Registry of candidate cis-Regulatory Elements (cCREs) is out 🧬
Huge thanks to the many collaborators, experimentalists, analysts and software developers who made this work possible — truly a team effort!
A "meme-torial" of the science is coming soon 👀
Huge thanks to the many collaborators, experimentalists, analysts and software developers who made this work possible — truly a team effort!
A "meme-torial" of the science is coming soon 👀
An expanded registry of candidate cis-regulatory elements - Nature
The existing ENCODE registry of candidate human and mouse cis-regulatory elements is expanded with the addition of new ENCODE data, integrating new functional data as well as new cell and tissue types...
www.nature.com
January 14, 2026 at 1:07 PM
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Excited to share @rbrianroome.bsky.social ‘s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org
This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.
www.science.org/doi/10.1126/...
This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.
www.science.org/doi/10.1126/...
Ontogeny of the spinal cord dorsal horn
The dorsal horn of the mammalian spinal cord is organized into laminae where each layer is populated by different neuron types, has distinctive circuit connections, and plays specialized roles in beha...
www.science.org
January 14, 2026 at 1:05 PM
🧪
Reposted by Gene Doctor Gene
BREAKING: New York City is flooded with peaceful anti-ICE protests and it’s driving the right insane. They needed riots. They needed excuses. Instead they got Americans calmly rejecting authoritarian bullshit in the streets.
January 11, 2026 at 10:51 PM
BREAKING: New York City is flooded with peaceful anti-ICE protests and it’s driving the right insane. They needed riots. They needed excuses. Instead they got Americans calmly rejecting authoritarian bullshit in the streets.
🧪 How indigenous knowledge advances ocean science across the world 🙏🌎🌍🌏 oceandecade.org/news/ocean-s...
Ocean science in action: How Indigenous Knowledge advances ocean science across the world - Ocean Decade
In this article, we showcase how the Ocean Decade amplifies Indigenous and local ocean stewardship.
oceandecade.org
January 11, 2026 at 5:23 PM
🧪 How indigenous knowledge advances ocean science across the world 🙏🌎🌍🌏 oceandecade.org/news/ocean-s...
🧪🙏 An Act of Cosmic Sabotage www.theatlantic.com/magazine/202...
An Act of Cosmic Sabotage
How Donald Trump tried to ground NASA’s science missions
www.theatlantic.com
January 8, 2026 at 6:27 PM
🧪🙏 An Act of Cosmic Sabotage www.theatlantic.com/magazine/202...
Reposted by Gene Doctor Gene
New study out in Systematics and Biodiversity!
Achatz 𝘦𝘵 𝘢𝘭. (2025) report the phylogeny and systematics of diplostomids (Digenea: Diplostomidae) from passeriform and cuculiform birds in South America.
Read the full study here: buff.ly/GBLlSOl #Taxonomy #Parasite #Biodiversity #Systematics
Achatz 𝘦𝘵 𝘢𝘭. (2025) report the phylogeny and systematics of diplostomids (Digenea: Diplostomidae) from passeriform and cuculiform birds in South America.
Read the full study here: buff.ly/GBLlSOl #Taxonomy #Parasite #Biodiversity #Systematics
January 2, 2026 at 9:30 AM
New study out in Systematics and Biodiversity!
Achatz 𝘦𝘵 𝘢𝘭. (2025) report the phylogeny and systematics of diplostomids (Digenea: Diplostomidae) from passeriform and cuculiform birds in South America.
Read the full study here: buff.ly/GBLlSOl #Taxonomy #Parasite #Biodiversity #Systematics
Achatz 𝘦𝘵 𝘢𝘭. (2025) report the phylogeny and systematics of diplostomids (Digenea: Diplostomidae) from passeriform and cuculiform birds in South America.
Read the full study here: buff.ly/GBLlSOl #Taxonomy #Parasite #Biodiversity #Systematics
Reposted by Gene Doctor Gene
Nicely summarised!! Thank you 👍
On an old and unsuccessful official project I tried to evolve NNs using genetic evolution.
More recently on my own, I took 2 weeks to get the evolution working - but only because it took so long to write the perceptron print-outs!
NNs evolve very nicely.
On an old and unsuccessful official project I tried to evolve NNs using genetic evolution.
More recently on my own, I took 2 weeks to get the evolution working - but only because it took so long to write the perceptron print-outs!
NNs evolve very nicely.
The organizational phenotypic effects of layered, interdependent transcription factors (TFs) are functionally analogous to a multilayered perceptron (MLP) in how they process information, though the underlying mechanisms of "training" differ significantly.
January 1, 2026 at 8:34 PM
Nicely summarised!! Thank you 👍
On an old and unsuccessful official project I tried to evolve NNs using genetic evolution.
More recently on my own, I took 2 weeks to get the evolution working - but only because it took so long to write the perceptron print-outs!
NNs evolve very nicely.
On an old and unsuccessful official project I tried to evolve NNs using genetic evolution.
More recently on my own, I took 2 weeks to get the evolution working - but only because it took so long to write the perceptron print-outs!
NNs evolve very nicely.
Reposted by Gene Doctor Gene
What the KENNEDY Center used to be…
Remember that time Aretha Franklin performed at the 2015 Kennedy Center Honors, paying tribute to Carole King, who co-wrote “You Make Me Feel Like A Natural Woman,” and it brought a tear to Obama’s eye and everyone to their feet? And Carole King’s reaction. Wow.
Remember that time Aretha Franklin performed at the 2015 Kennedy Center Honors, paying tribute to Carole King, who co-wrote “You Make Me Feel Like A Natural Woman,” and it brought a tear to Obama’s eye and everyone to their feet? And Carole King’s reaction. Wow.
January 1, 2026 at 5:04 AM
What the KENNEDY Center used to be…
Remember that time Aretha Franklin performed at the 2015 Kennedy Center Honors, paying tribute to Carole King, who co-wrote “You Make Me Feel Like A Natural Woman,” and it brought a tear to Obama’s eye and everyone to their feet? And Carole King’s reaction. Wow.
Remember that time Aretha Franklin performed at the 2015 Kennedy Center Honors, paying tribute to Carole King, who co-wrote “You Make Me Feel Like A Natural Woman,” and it brought a tear to Obama’s eye and everyone to their feet? And Carole King’s reaction. Wow.
🧪
Yup - it's not just about protein coding. It's clear from the ENCODE project results that 90% or more of evolution in general -not just of cognition- is done by genes regulating each other. It's so neatly managed now that the network looks just like a 3-layer perceptron:
December 30, 2025 at 11:49 PM
🧪
Reposted by Gene Doctor Gene
Yup - it's not just about protein coding. It's clear from the ENCODE project results that 90% or more of evolution in general -not just of cognition- is done by genes regulating each other. It's so neatly managed now that the network looks just like a 3-layer perceptron:
December 30, 2025 at 9:09 PM
Yup - it's not just about protein coding. It's clear from the ENCODE project results that 90% or more of evolution in general -not just of cognition- is done by genes regulating each other. It's so neatly managed now that the network looks just like a 3-layer perceptron:
🧪 Scientists are learning more about higher levels of emergent interactions between transcription factors- is this a new 🔑 to understanding both primitive and sentient cognition phenotypes in animal neuroscience?
Lee et al. used B-lymphoblastoid cells from three great ape species and humans to show that human ZEB2 is distinct in regulating a larger repertoire of genes implicated in neuronal development.
🔗 doi.org/10.1093/molbev/msaf318
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf318
#evobio #molbio
Comparing great apes reveals human-specific ZEB2 roles in neural development
Abstract. Humans differ from other primates in various traits, despite nearly identical protein-coding sequences. Understanding the evolution of these diff
doi.org
December 28, 2025 at 6:03 PM
🧪 Scientists are learning more about higher levels of emergent interactions between transcription factors- is this a new 🔑 to understanding both primitive and sentient cognition phenotypes in animal neuroscience?
Reposted by Gene Doctor Gene
Lee et al. used B-lymphoblastoid cells from three great ape species and humans to show that human ZEB2 is distinct in regulating a larger repertoire of genes implicated in neuronal development.
🔗 doi.org/10.1093/molbev/msaf318
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf318
#evobio #molbio
Comparing great apes reveals human-specific ZEB2 roles in neural development
Abstract. Humans differ from other primates in various traits, despite nearly identical protein-coding sequences. Understanding the evolution of these diff
doi.org
December 26, 2025 at 1:06 PM
Lee et al. used B-lymphoblastoid cells from three great ape species and humans to show that human ZEB2 is distinct in regulating a larger repertoire of genes implicated in neuronal development.
🔗 doi.org/10.1093/molbev/msaf318
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf318
#evobio #molbio
Nature
Restoring youth to old immune cells: mRNA therapy turns back the clock
Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
By Heidi Ledford
🧪 www.nature.com/articles/d41...
Restoring youth to old immune cells: mRNA therapy turns back the clock
Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
By Heidi Ledford
🧪 www.nature.com/articles/d41...
Restoring youth to old immune cells: mRNA therapy turns back the clock
Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
www.nature.com
December 18, 2025 at 7:02 PM
Nature
Restoring youth to old immune cells: mRNA therapy turns back the clock
Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
By Heidi Ledford
🧪 www.nature.com/articles/d41...
Restoring youth to old immune cells: mRNA therapy turns back the clock
Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
By Heidi Ledford
🧪 www.nature.com/articles/d41...