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JAMA Cardiology
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JAMA Cardiology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/49u3JQz
January 19, 2026 at 12:00 PM
Among patients with severe symptomatic aortic stenosis at low to intermediate surgical risk, transcatheter aortic valve implantation was associated with a lower 1-year risk of all-cause death or any stroke. ja.ma/4jQyWkw
January 18, 2026 at 4:00 PM
💬 Editors Note: Many post-TAVR conduction abnormalities resolve quickly and do not predict delayed heart block, suggesting routine permanent pacemaker implantation is often unnecessary.

ja.ma/49XYxnY
January 18, 2026 at 1:00 PM
Meta-analysis of four randomized trials found β-blockers did not reduce mortality, recurrent #MyocardialInfarction (MI), heart failure, or revascularization in patients with preserved left ventricular ejection fraction after MI. ja.ma/45QnMGr
January 17, 2026 at 2:00 PM
Among 409 patients undergoing #transcatheter aortic valve replacement, intraprocedural block occurred in the atrioventricular node or His bundle, with site-specific predictors for intraprocedural and delayed heart block.

ja.ma/4sLv3B6
January 17, 2026 at 1:00 PM
In this population-based cohort study, higher BP levels in adolescence were associated with a dose-dependent higher risk for atherosclerosis in middle age, particularly for severe coronary atherosclerosis. ja.ma/4jMAnjN
January 16, 2026 at 1:00 PM
Severe tricuspid regurgitation (TR) remains associated with poor prognosis and presents diagnostic and treatment challenges.

📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.

ja.ma/4sM2y6E
January 15, 2026 at 1:00 PM
Among adults with #Hypertension, #prediabetes combined with subclinical myocardial injury or stress identified by cardiac biomarkers is associated with a markedly higher risk of incident #HeartFailure.

ja.ma/3LNXbTD

January 14, 2026 at 8:35 PM
Among patients with severe symptomatic aortic stenosis at low to intermediate surgical risk, transcatheter aortic valve implantation was associated with a lower 1-year risk of all-cause death or any stroke. ja.ma/4bff73M
January 14, 2026 at 1:00 PM
Initial testing choice between coronary CTA and stress testing for suspected CAD showed no difference in all-cause or cardiovascular mortality among patients with stable symptoms. ja.ma/49eeJRR
January 10, 2026 at 4:00 PM
Meta-analysis of four randomized trials found β-blockers did not reduce mortality, recurrent #MyocardialInfarction (MI), heart failure, or revascularization in patients with preserved left ventricular ejection fraction after MI. ja.ma/4ptkksh
January 10, 2026 at 2:00 PM
A previously healthy female teenager presents with chest tightness and syncope after exertion. Electrocardiogram results showed ST-segment elevation in leads V1 through V4, aVL, and aVR troponin T levels.

What would you do next? ja.ma/4sxxvLB
January 9, 2026 at 3:00 PM
RCT: Intracardiac echocardiography is non-inferior to transesophageal echocardiography for thromboembolic prevention in atrial fibrillation ablation, with added benefits in safety, efficiency, and patient comfort. ja.ma/4js7aKM
January 9, 2026 at 12:00 PM
Low operator procedural volume for transcatheter aortic valve replacement and mitral transcatheter edge-to-edge repair was associated with increased 30-day procedural complications and adverse composite outcomes.

ja.ma/49ms1uh
January 8, 2026 at 4:15 PM
Monthly subcutaneous SHR-1918, a fully human monoclonal antibody targeting ANGPTL3, was associated with reduced LDL-C in adults with homozygous familial #hypercholesterolemia on stable lipid-lowering therapy. ja.ma/3LpfVbO
January 8, 2026 at 3:00 PM
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/3MVV4xt
January 8, 2026 at 12:00 PM
Very high lipoprotein(a) levels are associated with increased 30-year risk of major #cardiovascular events, coronary heart disease, ischemic #stroke, and cardiovascular death among healthy women.

ja.ma/49rqjIe
January 7, 2026 at 5:00 PM
In the Sarcomeric Human Cardiomyopathy Registry, lower household income and higher social deprivation index were each associated with higher rates of heart failure, arrhythmias, and mortality in #HypertrophicCardiomyopathy.

ja.ma/45H74ZX
January 7, 2026 at 4:30 PM
Among patients with #AtrialFibrillation, elevated BMI, and 1 or more additional cardiometabolic risk factors, aggressive risk factor management reduced arrhythmia recurrence over the 12-month period after catheter ablation. ja.ma/4snlYOX
January 6, 2026 at 1:00 PM
From @jama.com: Among older adults with suspected lower extremity deep vein thrombosis (DVT), an age-adjusted D-dimer cutoff safely increased the proportion of individuals who could be ruled out for DVT without additional imaging.

ja.ma/3YqfYY4
January 6, 2026 at 12:00 PM
#Semaglutide consistently lowered hospitalization rates and hospital days in high-risk adults with #obesity and cardiovascular disease, with effects observed across clinical subgroups. ja.ma/49b62q0
January 4, 2026 at 3:00 PM
Initial testing choice between coronary CTA and stress testing for suspected CAD showed no difference in all-cause or cardiovascular mortality among patients with stable symptoms. ja.ma/3LdrnaE
January 4, 2026 at 12:00 PM
Integrating common, rare, and somatic genetic variants with clinical factors improves risk prediction for incident atrial fibrillation, aiding screening and prevention efforts. ja.ma/4q2SPaj
January 2, 2026 at 2:00 PM
A secondary analysis of the TEMPO-2 RCT found no significant improvement in outcomes for minor ischemic stroke patients treated with intravenous tenecteplase, regardless of the presence of disabling deficits.

ja.ma/3YgnOTZ
January 1, 2026 at 4:00 PM
#Semaglutide consistently lowered hospitalization rates and hospital days in high-risk adults with #obesity and cardiovascular disease, with effects observed across clinical subgroups.

ja.ma/4pf47Xx
January 1, 2026 at 2:00 PM