JAMA Neurology
@jamaneurology.com
JAMA Neurology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
🌐 JAMANeurology.com
🌐 JAMANeurology.com
While incidence rates for central nervous system cancer remained stable from 1990 to 2021, both mortality and disability-adjusted life-years (DALYs) declined. ja.ma/3NMs37v
January 16, 2026 at 1:00 PM
While incidence rates for central nervous system cancer remained stable from 1990 to 2021, both mortality and disability-adjusted life-years (DALYs) declined. ja.ma/3NMs37v
💬 Editorial: Direct-to-consumer #Alzheimer blood tests risk misuse and misinformation; regulation and clinician-led implementation are critical for safe adoption.
ja.ma/3LGishU
ja.ma/3LGishU
January 15, 2026 at 3:00 PM
💬 Editorial: Direct-to-consumer #Alzheimer blood tests risk misuse and misinformation; regulation and clinician-led implementation are critical for safe adoption.
ja.ma/3LGishU
ja.ma/3LGishU
Meta-analysis confirms plasma p-tau217 as a strong candidate for early #Alzheimer screening, pending preventive therapies and regulatory guidance. ja.ma/4pBrElH
January 15, 2026 at 1:00 PM
Meta-analysis confirms plasma p-tau217 as a strong candidate for early #Alzheimer screening, pending preventive therapies and regulatory guidance. ja.ma/4pBrElH
Adults with #DownSyndrome and amyloid-positive #AlzheimerDisease had higher alignment between clinical and biological staging compared to sporadic cases. ja.ma/4aRa35I
January 13, 2026 at 3:00 PM
Adults with #DownSyndrome and amyloid-positive #AlzheimerDisease had higher alignment between clinical and biological staging compared to sporadic cases. ja.ma/4aRa35I
Among offspring born in Norway between 1967 and 1989, exposure to maternal diabetes and being born large for gestational age were associated with increased risk of adult-onset #MultipleSclerosis. ja.ma/3YykELq
January 12, 2026 at 4:30 PM
Among offspring born in Norway between 1967 and 1989, exposure to maternal diabetes and being born large for gestational age were associated with increased risk of adult-onset #MultipleSclerosis. ja.ma/3YykELq
Early relapse is common in #PCNSV, with normal cerebrospinal fluid associated with increased recurrence, suggesting current monitoring and treatment strategies may need adjustment. ja.ma/49tZVNT
January 10, 2026 at 4:00 PM
Early relapse is common in #PCNSV, with normal cerebrospinal fluid associated with increased recurrence, suggesting current monitoring and treatment strategies may need adjustment. ja.ma/49tZVNT
HHV-6 was identified as a rare cause of fulminant acute hemorrhagic leukoencephalitis in an immunocompetent adult.
ja.ma/3YqjOAj
ja.ma/3YqjOAj
January 9, 2026 at 2:00 PM
HHV-6 was identified as a rare cause of fulminant acute hemorrhagic leukoencephalitis in an immunocompetent adult.
ja.ma/3YqjOAj
ja.ma/3YqjOAj
Case report: a 23-year-old pregnant woman presented with seizures and chronic hepatitis B, with hyperintense lesions discovered in the left caudate nucleus on magnetic resonance imaging.
ja.ma/45CzNix
ja.ma/45CzNix
January 8, 2026 at 2:00 PM
Case report: a 23-year-old pregnant woman presented with seizures and chronic hepatitis B, with hyperintense lesions discovered in the left caudate nucleus on magnetic resonance imaging.
ja.ma/45CzNix
ja.ma/45CzNix
Early relapse is common in #PCNSV, with normal cerebrospinal fluid associated with increased recurrence, suggesting current monitoring and treatment strategies may need adjustment. ja.ma/3NvWb70
January 7, 2026 at 3:00 PM
Early relapse is common in #PCNSV, with normal cerebrospinal fluid associated with increased recurrence, suggesting current monitoring and treatment strategies may need adjustment. ja.ma/3NvWb70
General anesthesia improved 90-day disability outcomes and increased the rate of successful reperfusion compared with moderate sedation in patients undergoing endovascular thrombectomy for acute ischemic stroke.
ja.ma/3LauTm7
ja.ma/3LauTm7
January 7, 2026 at 12:00 PM
General anesthesia improved 90-day disability outcomes and increased the rate of successful reperfusion compared with moderate sedation in patients undergoing endovascular thrombectomy for acute ischemic stroke.
ja.ma/3LauTm7
ja.ma/3LauTm7
In a patient with #MMA, new-onset dystonic posturing, blepharospasm, and abnormal gait were associated with structural lesions in the globus pallidus and bilateral defects in dopamine transporter function on PET imaging. ja.ma/3Lgjn8M
January 6, 2026 at 3:00 PM
In a patient with #MMA, new-onset dystonic posturing, blepharospasm, and abnormal gait were associated with structural lesions in the globus pallidus and bilateral defects in dopamine transporter function on PET imaging. ja.ma/3Lgjn8M
Among patients with #Preeclampsia, postpartum blood pressure self-management was linked to larger putamen, accumbens and pallidum volumes vs usual care. ja.ma/3NuSvT1
January 5, 2026 at 4:30 PM
Among patients with #Preeclampsia, postpartum blood pressure self-management was linked to larger putamen, accumbens and pallidum volumes vs usual care. ja.ma/3NuSvT1
Frontotemporal #dementia is comparable in frequency to dementia with Lewy bodies and occurs at higher rates than progressive supranuclear palsy, corticobasal syndrome, and amyotrophic lateral sclerosis.
ja.ma/4sqalqe
ja.ma/4sqalqe
January 5, 2026 at 1:00 PM
Frontotemporal #dementia is comparable in frequency to dementia with Lewy bodies and occurs at higher rates than progressive supranuclear palsy, corticobasal syndrome, and amyotrophic lateral sclerosis.
ja.ma/4sqalqe
ja.ma/4sqalqe
In patients with ischemic stroke and concurrent nonvalvular atrial fibrillation and ASCVD, adding an antiplatelet agent to anticoagulant therapy offered no net clinical benefit over anticoagulant monotherapy.
ja.ma/44WEF1Q
ja.ma/44WEF1Q
January 4, 2026 at 12:00 PM
In patients with ischemic stroke and concurrent nonvalvular atrial fibrillation and ASCVD, adding an antiplatelet agent to anticoagulant therapy offered no net clinical benefit over anticoagulant monotherapy.
ja.ma/44WEF1Q
ja.ma/44WEF1Q
Among patients <70 years with acute #BasilarArteryOcclusion, endovascular thrombectomy doubled the rate of ambulatory and self-care capable outcomes at 3 years vs medical treatment.
ja.ma/4pbsSDX
ja.ma/4pbsSDX
January 2, 2026 at 4:00 PM
Among patients <70 years with acute #BasilarArteryOcclusion, endovascular thrombectomy doubled the rate of ambulatory and self-care capable outcomes at 3 years vs medical treatment.
ja.ma/4pbsSDX
ja.ma/4pbsSDX
A secondary analysis of the TEMPO-2 RCT found no significant improvement in outcomes for minor ischemic stroke patients treated with intravenous tenecteplase, regardless of the presence of disabling deficits.
ja.ma/4sm7jn4
ja.ma/4sm7jn4
January 1, 2026 at 3:00 PM
A secondary analysis of the TEMPO-2 RCT found no significant improvement in outcomes for minor ischemic stroke patients treated with intravenous tenecteplase, regardless of the presence of disabling deficits.
ja.ma/4sm7jn4
ja.ma/4sm7jn4
💬 Viewpoint: Chronic immune-mediated peripheral nerve myelinopathies (CIPNM) require precise diagnosis and updated nomenclature due to diverse clinical presentations.
ja.ma/4pmN4mu
ja.ma/4pmN4mu
January 1, 2026 at 1:00 PM
💬 Viewpoint: Chronic immune-mediated peripheral nerve myelinopathies (CIPNM) require precise diagnosis and updated nomenclature due to diverse clinical presentations.
ja.ma/4pmN4mu
ja.ma/4pmN4mu
Among patients <70 years with acute #BasilarArteryOcclusion, endovascular thrombectomy doubled the rate of ambulatory and self-care capable outcomes at 3 years vs medical treatment.
ja.ma/4jnUUej
ja.ma/4jnUUej
December 31, 2025 at 2:00 PM
Among patients <70 years with acute #BasilarArteryOcclusion, endovascular thrombectomy doubled the rate of ambulatory and self-care capable outcomes at 3 years vs medical treatment.
ja.ma/4jnUUej
ja.ma/4jnUUej
Among patients <70 years with acute #BasilarArteryOcclusion, endovascular thrombectomy doubled the rate of ambulatory and self-care capable outcomes at 3 years vs medical treatment.
ja.ma/4jdqGKQ
ja.ma/4jdqGKQ
December 29, 2025 at 4:30 PM
Among patients <70 years with acute #BasilarArteryOcclusion, endovascular thrombectomy doubled the rate of ambulatory and self-care capable outcomes at 3 years vs medical treatment.
ja.ma/4jdqGKQ
ja.ma/4jdqGKQ
In patients with ischemic stroke and concurrent nonvalvular atrial fibrillation and ASCVD, adding an antiplatelet agent to anticoagulant therapy offered no net clinical benefit over anticoagulant monotherapy. ja.ma/4atDFWx
December 27, 2025 at 12:00 PM
In patients with ischemic stroke and concurrent nonvalvular atrial fibrillation and ASCVD, adding an antiplatelet agent to anticoagulant therapy offered no net clinical benefit over anticoagulant monotherapy. ja.ma/4atDFWx
Earlier initiation of tofersen slowed clinical decline, sustained biomarker improvement, and extended survival for SOD1-related #ALS, with no new long-term safety concerns.
ja.ma/3MSbSVV
ja.ma/3MSbSVV
December 26, 2025 at 3:00 PM
Earlier initiation of tofersen slowed clinical decline, sustained biomarker improvement, and extended survival for SOD1-related #ALS, with no new long-term safety concerns.
ja.ma/3MSbSVV
ja.ma/3MSbSVV
The numbers are in.
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/4saoMP5
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/4saoMP5
December 25, 2025 at 12:00 PM
The numbers are in.
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/4saoMP5
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/4saoMP5
Earlier initiation of tofersen slowed clinical decline, sustained biomarker improvement, and extended survival for SOD1-related #ALS, with no new long-term safety concerns.
ja.ma/4qqOZaF
ja.ma/4qqOZaF
December 24, 2025 at 4:00 PM
Earlier initiation of tofersen slowed clinical decline, sustained biomarker improvement, and extended survival for SOD1-related #ALS, with no new long-term safety concerns.
ja.ma/4qqOZaF
ja.ma/4qqOZaF
A 62-year-old man presented with progressive limb weakness and involuntary movements. Take the Clinical Challenge.
What is your diagnosis?
ja.ma/3MP4oTI
What is your diagnosis?
ja.ma/3MP4oTI
December 24, 2025 at 12:00 PM
A 62-year-old man presented with progressive limb weakness and involuntary movements. Take the Clinical Challenge.
What is your diagnosis?
ja.ma/3MP4oTI
What is your diagnosis?
ja.ma/3MP4oTI
The numbers are in.
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/4jk4HlG
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/4jk4HlG
December 23, 2025 at 4:30 PM
The numbers are in.
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/4jk4HlG
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/4jk4HlG