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Reposted by Jacob Brandenburg

Rhett Rautsaw @reptilerhett.bsky.social · Aug 28

Get the most out of your HiFi data with @pacbio.bsky.social tools! Available for free on GitHub and bioconda/containers

PacBio @pacbio.bsky.social · Aug 28

Unlock the power of #PacBio HiFi whole genome sequencing in our 4-part video series.

Learn from PacBio scientists as they walk through tools and examples for variant calling, tandem repeat analysis, paralogous gene resolution, and star (*)-allele calling.

Sign up: bit.ly/3HV8Fmh

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Jacob Brandenburg @jbrandenburg13.bsky.social · Aug 27

Yeah, it might not hit your ideal price per sample, but in terms of providing the data you are looking for. It’s the cheapest option you likely have. Hopefully sequencing will continue its trend of coming down in price. Good luck! Let us know what you find out 🤞🏻

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Jacob Brandenburg @jbrandenburg13.bsky.social · Aug 27

5-7X HiFi coverage per haplotype is probably your best bet for phasing and identifying SVs in high het maize. You should check with the team at Veil Genomics. They are a company designed for this exact type of work.

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Jacob Brandenburg @jbrandenburg13.bsky.social · Jun 12

This Father’s Day, we’re celebrating HiFi dad-a with some cutting-edge science!

Researchers @elliecat.bsky.social at UC Riverside and @scarey.bsky.social at HudsonAlpha Institute for Biotechnology are revealing parts of the Y chromosome that were previously a mystery. www.pacb.com/blog/celebra...

Celebrating Father’s Day with new discoveries of the Y chromosome achieved with HiFi sequencing - PacBio

Featuring the Y chromosome - showcasing the power of HiFi sequencing to illuminate regions of the genome long considered out of reach

www.pacb.com

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Jacob Brandenburg @jbrandenburg13.bsky.social · Feb 11

Meet Jonathan 🐢 the world's longest living terrestrial animal at 192 years old.

Researchers published a pre-print analyzing the DNA sequence and methylome looking for age-related changes in DNA methylation and methylation entropy. Read more about the study here: www.biorxiv.org/content/10.1...

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Reposted by Jacob Brandenburg

PacBio @pacbio.bsky.social · Feb 6

Hi-C users, the wait is finally over! 🙌🏽 CiFi now enables Hi-C with #HiFisequencing. Short-read Hi-C struggles when it comes to repetitive and low-complexity regions. #PacBio HiFi rises to the challenge with better accuracy and lower input requirements. Congrats Megan and UC Davis team!

Megan Dennis @mydennis.bsky.social · Feb 5

Check out our new preprint describing CiFi - a method that couples 3C and PacBio HiFi sequencing with low input requirements. We apply it to human GM12878 to better characterize chromatin across repetitive regions, as well as single insect samples (a mosquito and a Mediterranean fruit fly).

bioRxiv Genomics @biorxiv-genomic.bsky.social · Feb 5

CiFi: Accurate long-read chromatin conformation capture with low-input requirements https://www.biorxiv.org/content/10.1101/2025.01.31.635566v1

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Jacob Brandenburg @jbrandenburg13.bsky.social · Jan 23

The future of trait mapping is HiFi low pass sequencing! Amazing pre-print from Dr. Kendall Lee out of the Clevenger lab. Their work is going to revolutionize genomic based breeding.
#PacBio #HiFisequencing

PacBio @pacbio.bsky.social · Jan 23

Explore how low-pass #HiFisequencing is transforming plant and animal genomics. 🌱🌍 Discover its potential to revolutionize breeding with precise trait mapping at a lower cost per insight, addressing agriculture's toughest challenges.

Blog here: bit.ly/4h7AaFA

#PacBio

Publication spotlight: Advancing plant breeding with long-read low-pass sequencing - PacBio

Low-pass HiFi sequencing offers more than 8x the cost efficiency of short reads while retaining the key advantages of long reads.

bit.ly

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Reposted by Jacob Brandenburg

PacBio @pacbio.bsky.social · Jan 12

Swing by Booth #219 at #PAG32 for exclusive giveaways and a demo of our new long-read benchtop sequencer, #Vega! Explore tailored solutions for your plant and animal #genomics research. Don’t miss out!

#PacBio

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Reposted by Jacob Brandenburg

PacBio @pacbio.bsky.social · Jan 12

Don't miss tomorrow's workshop in Ballroom C! Join us to explore how PacBio #HiFisequencing is advancing research in conservation, sustainability, and global health. Learn how high-accuracy #sequencing is shaping a brighter future for our planet. See you there!

#PacBio #PAG32

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Reposted by Jacob Brandenburg

PacBio @pacbio.bsky.social · Jan 8

It’s Day 2 of the #PacBio Battle of the Plant vs. Animal Genomes trivia series for #PAG32! 🪴🐻

Answer today’s question correctly in the comments, follow @pacbio.bsky.social, and tag a friend for a chance to win a prize. Final question tomorrow! T&Cs: bit.ly/3O3AfhD

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Reposted by Jacob Brandenburg

PacBio @pacbio.bsky.social · Jan 7

We’re kicking off the #PacBio Battle of the Plant vs. Animal Genomes trivia series for #PAG32! 🌾🐸

Answer today’s question correctly in the comments, follow @pacbio.bsky.social, and tag a friend for a chance to win a prize. Stay tuned for tomorrow’s question! T&Cs: bit.ly/3O3AfhD

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Jacob Brandenburg @jbrandenburg13.bsky.social · Dec 19

Come party with me at PAG 2025!!

PacBio @pacbio.bsky.social · Dec 19

Join #PacBio for A Bright New Day at PAG 2025! Celebrate discoveries driving plant and animal genomics with live music, dinner, cocktails, and networking. Registration and a PAG conference badge are required for entry.

Register: bit.ly/41DahZl

#PAG32

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Reposted by Jacob Brandenburg

PacBio @pacbio.bsky.social · Dec 11

A bright new day for plant and animal #genomics is here! Join #PacBio at PAG 2025 in San Diego to explore the power of #HiFisequencing. Visit our booth, attend our workshop, or schedule a one-on-one meeting.

Details here: bit.ly/41hR9Qw

#PAG32

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