Dr Jess Buttress
@jbuttresssci.bsky.social
99 followers 97 following 4 posts
PDRA and microbiologist investigating the role of IM30 proteins in bacterial membrane repair at CBCB, Newcastle University 🔬🦠
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jbuttresssci.bsky.social
Possibly outing myself as the biggest nerd ever here but what a massive day for Ryan Sharpe, Oakville, Ontario, Canada appearing on both US Jeopardy and UK University Challenge!!
Reposted by Dr Jess Buttress
Reposted by Dr Jess Buttress
cbcb-newcastle.bsky.social
We are happy to join the science community at BlueSky! #MicroSky
Reposted by Dr Jess Buttress
biorxiv-microbiol.bsky.social
Single molecule imaging of RecB in vivo reveals dynamics of DNA Double Strand Break repair in Escherichia coli https://www.biorxiv.org/content/10.1101/2024.12.18.629153v1
jbuttresssci.bsky.social
This has been an ongoing collaboration with Michaela Wenzel’s group since my PhD days so a huge thank you to everyone involved @alansckoh.bsky.social @henrikstrahl.bsky.social and hopefully this provides some cool results/techniques for upcoming AMR research! (3/3) #microsky
jbuttresssci.bsky.social
ii) daptomycin’s ability to cluster fluid lipid domains requires cell wall precursor lipids whilst membrane depolarisation does not, and finally, the Bacillus IM30 protein LiaH seems to play an intriguing role in clustering these daptomycin-cell wall precursor lipid complexes. (2/3)
jbuttresssci.bsky.social
So happy our pre-print on daptomycin mechanism of action is now out! Here, we present three main findings: i) daptomycin does not form large membrane pores in either B. subtilis or S. aureus, (1/3)
biorxiv-microbiol.bsky.social
The last resort antibiotic daptomycin exhibits two independent antibacterial mechanisms of action https://www.biorxiv.org/content/10.1101/2024.12.20.629673v1