Kate Beckham
@kshbeckham.bsky.social
Royal Society University Research Fellow | NUAcT Fellow @ Newcastle University @mhd-newcastle.bsky.social
Investigating mycobacterial transport systems
#structuralbiology #microbiology
Instagram @kshbeckham
Investigating mycobacterial transport systems
#structuralbiology #microbiology
Instagram @kshbeckham
Pinned
www.findaphd.com
BBSSRC (NEEDL) funded PhD studentship in my lab co-supervised by
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
Reposted by Kate Beckham
PhD position available in our team to study how UPEC exploits metals to successfully colonise the host gut. Cool collaboration with @thecopperdoctor.bsky.social and @banzhaflab.bsky.social Please share and get in touch for more details
Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University on FindAPhD.com
PhD Project - Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University, listed on FindAPhD.com
www.findaphd.com
January 23, 2026 at 7:38 PM
PhD position available in our team to study how UPEC exploits metals to successfully colonise the host gut. Cool collaboration with @thecopperdoctor.bsky.social and @banzhaflab.bsky.social Please share and get in touch for more details
Reposted by Kate Beckham
www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!
Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University on FindAPhD.com
PhD Project - Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University, listed on FindAPhD.com
www.findaphd.com
January 23, 2026 at 10:33 AM
www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!
BBSSRC (NEEDL) funded PhD studentship in my lab co-supervised by
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
www.findaphd.com
January 23, 2026 at 12:34 PM
BBSSRC (NEEDL) funded PhD studentship in my lab co-supervised by
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
Reposted by Kate Beckham
Our latest CRISPR ring nuclease paper focusses on Csx15 - which seems to act as of a sponge as well as a canonical phosphodiesterase. Great work led by @haotianchi.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
January 22, 2026 at 8:57 AM
Our latest CRISPR ring nuclease paper focusses on Csx15 - which seems to act as of a sponge as well as a canonical phosphodiesterase. Great work led by @haotianchi.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Kate Beckham
THE NEXT INSTALLMENT OF BIOLOGY OF MYOCBACTERIA GRC WILL BE IN 2028, NOT 2027. Exact date and location TBD. Sorry about the long wait, but we think it is better long term. PLEASE repost/tell your friends!
January 21, 2026 at 7:19 PM
THE NEXT INSTALLMENT OF BIOLOGY OF MYOCBACTERIA GRC WILL BE IN 2028, NOT 2027. Exact date and location TBD. Sorry about the long wait, but we think it is better long term. PLEASE repost/tell your friends!
Reposted by Kate Beckham
Our new movie is online, highlighting the assembly, secretion and mechanism of action of bacterial Tc toxins. We hope you enjoy it and use it for teaching purposes or just for fun. Nature is fascinating!
www.youtube.com/watch?v=UfEf...
www.youtube.com/watch?v=UfEf...
How bacterial Tc toxins work: secretion, pore formation and host cell disruption.
YouTube video by Max Planck Institute of Molecular Physiology
www.youtube.com
January 15, 2026 at 8:24 AM
Our new movie is online, highlighting the assembly, secretion and mechanism of action of bacterial Tc toxins. We hope you enjoy it and use it for teaching purposes or just for fun. Nature is fascinating!
www.youtube.com/watch?v=UfEf...
www.youtube.com/watch?v=UfEf...
Reposted by Kate Beckham
Structural elucidation of the hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis www.biorxiv.org/content/10.64898/2026.01.07.698164v1 #cryoem
January 9, 2026 at 12:00 PM
Structural elucidation of the hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis www.biorxiv.org/content/10.64898/2026.01.07.698164v1 #cryoem
Reposted by Kate Beckham
Are you working on challenging projects in structural biology?
#EMBOMacromolecular will highlight the strategic use of cutting-edge protein structure prediction methods, and recent advances in in situ structural biology. Apply by 18 Feb to join us at EMBL Grenoble! 🧬
s.embl.org/mmo26-01-bl
#EMBOMacromolecular will highlight the strategic use of cutting-edge protein structure prediction methods, and recent advances in in situ structural biology. Apply by 18 Feb to join us at EMBL Grenoble! 🧬
s.embl.org/mmo26-01-bl
January 9, 2026 at 9:24 AM
Are you working on challenging projects in structural biology?
#EMBOMacromolecular will highlight the strategic use of cutting-edge protein structure prediction methods, and recent advances in in situ structural biology. Apply by 18 Feb to join us at EMBL Grenoble! 🧬
s.embl.org/mmo26-01-bl
#EMBOMacromolecular will highlight the strategic use of cutting-edge protein structure prediction methods, and recent advances in in situ structural biology. Apply by 18 Feb to join us at EMBL Grenoble! 🧬
s.embl.org/mmo26-01-bl
Reposted by Kate Beckham
Applications to our 2026 Summer Student Training Programme are now open.
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
Summer students
Our nine-week summer training programme provides undergraduates with hands-on experience of working in a research lab.
www.crick.ac.uk
January 8, 2026 at 9:39 AM
Applications to our 2026 Summer Student Training Programme are now open.
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
We’re looking for undergrad students to join us for nine weeks this summer.
See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...
Reposted by Kate Beckham
🛎️🛎️ Looking for a postdoctoral fellowship? Interested in tackling real-world challenges?
Then check out EMBL's EIPOD-LinC fellowships. Gain transferable skills and work on self-designed projects to make a lasting impact on global issues.
📆 Closing date: 2 February
www.embl.org/about/info/p...
Then check out EMBL's EIPOD-LinC fellowships. Gain transferable skills and work on self-designed projects to make a lasting impact on global issues.
📆 Closing date: 2 February
www.embl.org/about/info/p...
January 7, 2026 at 8:36 AM
🛎️🛎️ Looking for a postdoctoral fellowship? Interested in tackling real-world challenges?
Then check out EMBL's EIPOD-LinC fellowships. Gain transferable skills and work on self-designed projects to make a lasting impact on global issues.
📆 Closing date: 2 February
www.embl.org/about/info/p...
Then check out EMBL's EIPOD-LinC fellowships. Gain transferable skills and work on self-designed projects to make a lasting impact on global issues.
📆 Closing date: 2 February
www.embl.org/about/info/p...
Reposted by Kate Beckham
🚨Last chance to apply for two PhD projects in my lab, applying structural biology and single molecule biophysics to investigate gene expression in RNA viruses: www.findaphd.com/phds/?Keywor...
www.findaphd.com
January 6, 2026 at 3:56 PM
🚨Last chance to apply for two PhD projects in my lab, applying structural biology and single molecule biophysics to investigate gene expression in RNA viruses: www.findaphd.com/phds/?Keywor...
Reposted by Kate Beckham
EMBL’s Sabbatical Fellowship Programme is slowly growing, attracting participants from around the world with its collaborative insights and access to world-class technologies.
www.embl.org/news/connect...
www.embl.org/news/connect...
A lab away from home | EMBL
The EMBL Sabbatical Fellowship Programme keeps growing, offering participants collaborative insights and access to world-class technology.
www.embl.org
January 5, 2026 at 12:50 PM
EMBL’s Sabbatical Fellowship Programme is slowly growing, attracting participants from around the world with its collaborative insights and access to world-class technologies.
www.embl.org/news/connect...
www.embl.org/news/connect...
Good news! Erasmus is a great scheme. www.bbc.com/news/article...
UK will rejoin Erasmus student scheme in 2027
The UK left in December 2020 as part of the post-Brexit trade deal with the EU negotiated by Boris Johnson.
www.bbc.com
December 17, 2025 at 2:07 PM
Good news! Erasmus is a great scheme. www.bbc.com/news/article...
Reposted by Kate Beckham
Fab afternoon at the MHD festive gathering 🎉 congratulations to the winning quiz team and @johncorrigall.bsky.social for most festive outfit.
December 15, 2025 at 3:37 PM
Fab afternoon at the MHD festive gathering 🎉 congratulations to the winning quiz team and @johncorrigall.bsky.social for most festive outfit.
Reposted by Kate Beckham
Truly heroic effort by Robin Lissner in
@wilbertbitter.bsky.social's group to knock out every single lipoprotein in Mycobacterium marinum. He found a lot of cool stuff, and we were fortunate to help out with some of it. Check out the paper here: journals.asm.org/doi/10.1128/...
@wilbertbitter.bsky.social's group to knock out every single lipoprotein in Mycobacterium marinum. He found a lot of cool stuff, and we were fortunate to help out with some of it. Check out the paper here: journals.asm.org/doi/10.1128/...
journals.asm.org
December 12, 2025 at 9:16 PM
Truly heroic effort by Robin Lissner in
@wilbertbitter.bsky.social's group to knock out every single lipoprotein in Mycobacterium marinum. He found a lot of cool stuff, and we were fortunate to help out with some of it. Check out the paper here: journals.asm.org/doi/10.1128/...
@wilbertbitter.bsky.social's group to knock out every single lipoprotein in Mycobacterium marinum. He found a lot of cool stuff, and we were fortunate to help out with some of it. Check out the paper here: journals.asm.org/doi/10.1128/...
Reposted by Kate Beckham
Mycobacterium tuberculosis is an outlier in many ways. One of them is keeping a high degree of functional redundancy despite its obligate pathogen lifestyle. In this review, we reflect on the biological meaning of M. tuberculosis functional redundancies.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Essential redundancies fuel Mycobacterium tuberculosis adaptation to the host
Redundancy in biology is, at a glance, counterintuitive because if the function of two gene products completely overlaps then, throughout the course of evolution, one of the genes will likely accumula...
journals.plos.org
December 7, 2025 at 12:07 PM
Mycobacterium tuberculosis is an outlier in many ways. One of them is keeping a high degree of functional redundancy despite its obligate pathogen lifestyle. In this review, we reflect on the biological meaning of M. tuberculosis functional redundancies.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Reposted by Kate Beckham
Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription.
www.cell.com/cell/fulltex...
Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.
www.cell.com/cell/fulltex...
Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.
Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites
Zhang, Todeschini, and Wu et al. show that the bacterial defense system Kiwa senses
phage attachment at the membrane and assembles a transmembrane complex that halts
infection by blocking phage DNA re...
www.cell.com
July 28, 2025 at 7:43 PM
Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription.
www.cell.com/cell/fulltex...
Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.
www.cell.com/cell/fulltex...
Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.
Reposted by Kate Beckham
If you or someone you know is looking for a post-doctoral position working on mycobacterial envelope biology, please get in touch. I am recruiting here at the University of Western Ontario in London, Ontario, Canada.
December 2, 2025 at 3:21 PM
If you or someone you know is looking for a post-doctoral position working on mycobacterial envelope biology, please get in touch. I am recruiting here at the University of Western Ontario in London, Ontario, Canada.
Great to have you in Newcastle @matthiaswilmanns.bsky.social
Fantastic to have Prof Matthias Wilmanns from EMBL Hamburg hosted by @kshbeckham.bsky.social to give a @mhd-newcastle.bsky.social seminar on mycobacterial infection #dreamtheme
December 2, 2025 at 1:35 PM
Great to have you in Newcastle @matthiaswilmanns.bsky.social
Reposted by Kate Beckham
Today, we are lucky to have Imane El Meouche from IAME, France to give a MCM seminar @medicalsciencesncl.bsky.social (chaired by @henrikstrahl.bsky.social) on antibiotics tolerance in E. Coli
December 1, 2025 at 1:07 PM
Today, we are lucky to have Imane El Meouche from IAME, France to give a MCM seminar @medicalsciencesncl.bsky.social (chaired by @henrikstrahl.bsky.social) on antibiotics tolerance in E. Coli
👀 nice was to illustrate :)
www.nature.com/articles/s41... I'm really liking the author's use of googly eyes in this paper 😀
December 1, 2025 at 12:36 PM
👀 nice was to illustrate :)
Nice work, congratulations all :)
Happy to see work I contributed to during my MSc at @bioscienceleeds.bsky.social with Jennifer Tomlinson’s lab out in @pnas.org! Everyone Bluesky-less except @antoncalabrese.bsky.social
www.pnas.org/doi/10.1073/...
#AMR #MRSA #NMR
www.pnas.org/doi/10.1073/...
#AMR #MRSA #NMR
Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G | PNAS
Fusidic acid (FA) is one of few remaining antibiotics active against Methicillin-resistant
Staphylococcus aureus. FusB confers resistance to FA by ...
www.pnas.org
November 27, 2025 at 12:14 PM
Nice work, congratulations all :)
Reposted by Kate Beckham
Type VII ABC transporters underpin many core activities in the bacterial cell envelope - including efflux, cell division and lipoprotein trafficking.
A new paper in PLOS Biology reveals YbbAP-TesA as a novel Type VII system in E. coli.
dx.plos.org/10.1371/jour...
A new paper in PLOS Biology reveals YbbAP-TesA as a novel Type VII system in E. coli.
dx.plos.org/10.1371/jour...
Structural characterization of the YbbAP-TesA ABC transporter identifies it as a lipid hydrolase complex that extracts hydrophobic compounds from the bacterial inner membrane
In E.coli, three of the four Type VII ABC transporter systems have been structurally characterized. This study solves cryo-EM structures of the fourth Type VII ABC system, YbbAP-TesA, and suggests tha...
dx.plos.org
November 26, 2025 at 12:46 PM
Type VII ABC transporters underpin many core activities in the bacterial cell envelope - including efflux, cell division and lipoprotein trafficking.
A new paper in PLOS Biology reveals YbbAP-TesA as a novel Type VII system in E. coli.
dx.plos.org/10.1371/jour...
A new paper in PLOS Biology reveals YbbAP-TesA as a novel Type VII system in E. coli.
dx.plos.org/10.1371/jour...