Join us for the Austrian Cryo-EM Symposium from Nov 11–12 at ISTA! Top speakers, cutting-edge cryo-EM, and a chance to explore Vienna & the ISTA campus. Register now 👉 cryoem-symposium.pages.ist.ac.at/registration/

#cryoEM

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

It's important to foster a good lab culture

www.cell.com/chem/fulltex...

We’re looking for an enthusiastic postdoc to join our team. 😊

The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪

The position is fully funded for 3 years.

Please share 🙏

Job description and application details (deadline: October 11th): www.cnio.es/en/empleo/po...

Helical Reconstruction of Amyloids in cryoSPARC?
We present guidelines, limitations & future perspectives for processing amyloids in cryoSPARC @structurabio.bsky.social.
Great collaboration of the Kelly Lab and @landerlab.bsky.social #cryoEM #amyloid www.biorxiv.org/content/10.1...

Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...

🥳🎉

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social

We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.

doi.org/10.1038/s415...

Here I am in 2020 in the flimsiest, most pitful PPE - like so many other NHS staff, some of whom died from the Covid they caught in their hospitals.

Tory peer Michelle Mone - who today lost her legal case & must repay the govt £122m - dares to claim she’s been ‘scapegoated’.

What, Michelle? 🧵

Today, @rcsbpdb.bsky.social introduces Q-score in EM validation reports. Q-score assesses model-map fit. A new percentile slider will compare an entry’s average Q-score to the full archive and a resolution-matched subset. This would help judge whether the fit is typical for the reported resolution.

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

It’s apoferritin being collected on a Tundra.

#cryoEM 🧪⚛️ Lena’s paper on imaging thick biological sections with STEM is finally published! We started this work almost 10 years ago. After Lena passed in 2023, I spent much of my sabbatical working with Yue and Steve to wrap this up. Also learned a lot about TEM vs STEM dose efficiency

I threw the map and model into Phenix, which the authors state that they used to validate their modelling. They also state there is good overlap between the density and their model.....

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

I feel some responsibility, as we develop the software. But helical reconstruction is prone to getting stuck in local minima, and unfortunately still requires a lot of self-criticism. The most important one: if you don't see expected features in the map, don't trust it!

Carve that last sentence in stone, alongside “if you can’t see your particles they are not there” and “if you can’t see your ligand do not try to just model it anyway”

Structural basis for a filamentous morpheein model of human cystathionine beta-synthase www.biorxiv.org/content/10.1101/2025.09.24.678195v1 #cryoem

Tilt-corrected bright-field scanning transmission electron microscopy (tcBF-STEM) offers enhanced contrast and dose efficiency for cryo-EM in thick biological specimens.

www.nature.com/articles/s41...

Wouldn't you say that systematic scientific misconduct (let's say, through neglect or actual fraud) going back decades should also be fully prosecuted? I am also unable to understand the politics here. It's a scientist reading a paper and seeing potential issues. Are we not allowed to talk about it?

The CDC’s newly reconstituted antivax ACIP met last week. The results weren’t as horrific as I’d expected, but not for lack of trying on the part of the antivax members. I’ll focus mainly on one presentation as a lens through which to look at the meeting. sciencebasedmedicine.org/robert-f-ken...