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Jennifer Reed @jenniferreed.bsky.social · Sep 2

Please join us tomorrow either online or in-person (Centre Foustanellas Auditorium [H-2367] at the University of Ottawa Heart Institute) to welcome Dr. John Buckley 👇

To register (free): lnkd.in/erFDe9-Q

@heartinstitute.bsky.social

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Jennifer Reed @jenniferreed.bsky.social · May 23

8. We hope that by sharing these findings, it will help inform future, successful trials. A thank you to the Co-PIs, Co-Is, and co-authors for their diligent and responsive efforts to see this trial and manuscript through.

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Jennifer Reed @jenniferreed.bsky.social · May 23

3️⃣ intervention: consider shorter duration interventions (<12weeks) and those offered sooner following listing.

4️⃣ sample size: consider up to 30% drop-out.

5️⃣ identify funding or logistical (e.g. virtual) opportunities to address reported barriers to participation (e.g. travel costs & distance).

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Jennifer Reed @jenniferreed.bsky.social · May 23

7. Many lessons learned:
1️⃣ logistics: consider challenges & solutions with multi-centre studies (e.g., how to integrate different clinical processes & care across centres).

2️⃣ eligibility: including an upper limit for the length of time since the patient has been listed for HTx

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Jennifer Reed @jenniferreed.bsky.social · May 23

6. 👟 n=2 patients in PREHAB: HIIT was safe as evidenced by no exercise-related adverse events and patients were able to sustain increases in mean peak power output (PPO) and heart rate (HR) from the first to last exercise bouts (see Figure).

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Jennifer Reed @jenniferreed.bsky.social · May 23

5. 🔎 Why so few patients?! Being transplanted, medication and device contraindications, trial commitment, transportation barriers, and HIIT not recommended by medical professionals (see detailed CONSORT).

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Jennifer Reed @jenniferreed.bsky.social · May 23

4. 📅 Trial recruitment began in October 2018 and closed, due to the COVID-19 pandemic, in October 2020. Of the 84 patients screened, 17 were eligible and consented to participate; 2 patients were randomized to each intervention group.

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Jennifer Reed @jenniferreed.bsky.social · May 23

3. 🏥 Study design: A multi-centre RCT with a target sample size of 60: n=30 > HIIT, n=30 > usual care (as per Canadian Cardiovascular Society guidelines).

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Jennifer Reed @jenniferreed.bsky.social · May 23

2. 🥅 Main goal of trial: We evaluated the impact of a 12-week program of PREHAB (i.e., high-intensity interval training [HIIT], stress management class, and nutritional workshop) compared with usual care in patients with advanced HF awaiting heart transplantation (HTx) on functional capacity.

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Jennifer Reed @jenniferreed.bsky.social · May 23

1. A 🏔️ during peer review was 📣 why failures are important to publish:

Our response: publication of ➖ clinical trial data is critical (to reduce publication bias & research waste, inform future trial designs, & adherence to ethical reporting for patients who participated in the research).

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Jennifer Reed @jenniferreed.bsky.social · May 23

Hear ye, Hear ye! Our PREHAB RCT failed, Read all about it.

🔗: www.cjcopen.ca/article/S258...

#hearttransplantation #HIIT #PREHAB #heartfailure #cardiacrehabilitation

🧵 (1-8) 👇

Cardiovascular Prehabilitation in Patients Awaiting Heart Transplantation - Addressing Clinical Needs (PREHAB HTx Study)

To compare the effects of a 12-week PREHAB program and usual care (UC) on functional capacity in adults listed for heart transplantation (HTx). Secondary aims including comparing peak oxygen uptake (V...

www.cjcopen.ca

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Reposted by Jennifer Reed

Isabela Marcal @isabelarmarcal.bsky.social · Apr 19

🧵1/8 | Our new review investigated sex-specific inclusion in Canadian exercise-based trials & cardiovascular disease (CVD) 🫀🏃‍♀️🇨🇦 Let’s break it down 👇

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Reposted by Jennifer Reed

StacesCases2 🇨🇦 📎 @stacescases2.bsky.social · Apr 26

@mark-carney.bsky.social delivers a DEATH BLOW against #PierrePoilievre!

'It's easy to be negative when you've never fixed anything.

It's easy to be negative when you've never built anything.

It's easy to be negative when you're a career politician who has never accomplished anything"
#Cdnpoli

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Jennifer Reed @jenniferreed.bsky.social · Apr 26

Reasons to focus on women’s cardiovascular disease risk factors 👇

#cwhhs2025
@heartinstitute.bsky.social
@cwhhalliance.bsky.social

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Jennifer Reed @jenniferreed.bsky.social · Apr 25

Kicking off the #cwhhs2025
@heartinstitute.bsky.social

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Reposted by Jennifer Reed

Bruce Fanjoy @brucefanjoy.bsky.social · Apr 24

Bruce can win this, but we need your help: Sign up to volunteer at the link in our bio. Together we can stop Pierre Poilievre and turn Carleton red.

#FanjoyVsPoilievre

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Reposted by Jennifer Reed

Bruce Fanjoy @brucefanjoy.bsky.social · Apr 23

Together we can vote to get Pierre to stop talking about your biological clock.

Did you know that your employer has to give you time off to go vote on Election Day? Make a plan, give your boss a heads up, and go vote!

#FanjoyVsPoilievre

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Jennifer Reed @jenniferreed.bsky.social · Apr 24

How can others help this weekend? Door knocking?

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Reposted by Jennifer Reed

Leeta 🇨🇦 @micropainter.bsky.social · Apr 21

Calgary Confederation & Calgary Centre are tied between Liberals and Cons.

NDP voters: orange is closer to red than blue.

Your vote may determine if Calgary gets real representation in a Carney majority government—or a former UCP MLA in opposition.

#ElbowsUp 🇨🇦 #yyc #Calgary #Alberta #cdnpoli

NDP voters: A strategic vote in Calgary Confederation is for Corey Hogan!

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Reposted by Jennifer Reed

PEIPolitical 🇨🇦 @peipolitical.bsky.social · Apr 21

PM Mark Carney 🇨🇦 Unveils Historic Economic Plan with Tax Cuts, NATO Spending & Reforms
Reduce spending growth, lower the deficit, balance the operating budget within 3 years without cutting vital transfers. Defence funding will also surpass NATO’s 2% target, a renewed international posture #cdnpoli

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Jennifer Reed @jenniferreed.bsky.social · Apr 20

A thread summarizing our recent review investigating sex-specific inclusion in exercise-based trials & cardiovascular disease 👇

Isabela Marcal @isabelarmarcal.bsky.social · Apr 19

🧵1/8 | Our new review investigated sex-specific inclusion in Canadian exercise-based trials & cardiovascular disease (CVD) 🫀🏃‍♀️🇨🇦 Let’s break it down 👇

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Jennifer Reed @jenniferreed.bsky.social · Apr 17

I spy with my little eye something that is missing:

Editors and publishers: please consider adding @bsky.app to options for sharing publications

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Jennifer Reed @jenniferreed.bsky.social · Apr 15

It is was a ⭐ learning opportunity to be involved in this mtg which brought together >30 Canadian adult and pediatric researchers, clinicians, and patient and family partners across solid organ transplant. TY colleagues.

Our published mtg report: shorturl.at/KGUpH

#OrganTransplants #rehabilitation

Frontiers | Establishment of emerging practices and research priorities for telerehabilitation in solid organ transplantation: meeting report and narrative literature review

shorturl.at

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Reposted by Jennifer Reed

Dr. Lucky Tran @luckytran.com · Apr 14

With current border policies, it is unethical to continue holding so many important science conferences in the US. In addition to moving conferences to safer international locations, US organizers must reorganize meetings around remote participation.

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Reposted by Jennifer Reed

Michael Byers 🇨🇦 @michael-byers.bsky.social · Apr 15

Canada's an even better place to vacation, and we don't disappear people to Guantanamo Bay and El Salvador. @governor.ca.gov

Governor Gavin Newsom @governor.ca.gov · Apr 15

The Golden State and Canada have always shared so much in common.

Sure, you-know-who is trying to stir things up back in DC, but don't let that ruin your vacation plans.

We’re launching a new international campaign to welcome and encourage Canadians to visit the Golden State.

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