And a great comms piece as usual by @ebi.embl.org

SAVANA is out in the wild 🦁! #SAVANA detects haplotype-resolved somatic structural variants (SVs), copy number aberrations, and calculates tumour purity and ploidy using long-read data. Together with it, a robust, data-driven benchmarking effort! Below is a thread with all the advantages 👇

Nature research paper: MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC

https://go.nature.com/41IPJwX

🧬 Novo estudo da #UniversidadeDeVerona, @uofglasgow.bsky.social & @champalimaudf.bsky.social revela como o #DNAExtracromossómico (#ecDNA) ajuda os tumores pancreáticos a resistirem aos tratamentos e a sobreviverem.
🔍 O resumo 👉🔗 shorturl.at/iJF8J
📄 O artigo 👉🔗 bit.ly/4ipKRUA

🧬 #ResearchWatch: Loss–Translocation–Amplification #Chromothripsis Drives #Osteosarcoma Evolution, a summary of the study by @jevalleinclan.bsky.social, Solange De Noon, Adrienne Flanagan, Isidro Cortes-Ciriano, and colleagues @ucl.ac.uk @ebi.embl.org @uclnews.bsky.social

doi.org/10.1158/2159...

Un equipo de científicos revela el mecanismo del osteosarcoma, un agresivo cáncer que afecta a niños y adolescentes y que se extiende desde los huesos: “Hay cromosomas que son como Frankenstein”

Osteosarcoma, an aggressive bone cancer, most commonly affects children and young adults.

New research solves the mystery of what drives the genomic rearrangements causing the aggressive development and evolution of osteosarcoma tumours.

www.ebi.ac.uk/about/news/r...
🧪

Expand your Bluesky network with R: Find people followed by the people you follow, but who you don't follow, using R and the atrrr package blog.stephenturner.us/p/expand-you... #Rstats

Not enough bioinformatics in your Bluesky feed? We’ve got you covered. Follow us for our latest news, exciting life science research, updates from our data resources, new tools and training resources.

Haven't heard of EMBL-EBI? Take a look at what we’re working on. www.ebi.ac.uk/about/our-im...

Portugal is rapidly losing its young people. Will this new scheme convince them to stay? | Adam Almeida

Something that's been bugging me for a while in bioinformatics data analysis is this overreliance on packages, workflows and what's been called "cargo cult science".

Can we have more conceptual thinking, more theory?
Asking for what we really want to achieve and what we need to do gets us there.

I want to open my Blusky by reminding that we are looking for a motivated PhD student to join our team at VHIO for a very exciting computational immuno-oncology project. Check out the position and apply! 💻🧬 #PhD #CompImmunoGenomics
vhio.net/vhio-phd-opp...