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Wolfgang Huber

@wkhuber.bsky.social

7.7K followers 2.3K following 510 posts

Statistician, Computational Biologist, R | Bioconductor. Love stats and ML. https://www.huber.embl.de Textbook: Modern Statistics for Modern Biology https://www.huber.embl.de/msmb/ (with @sherlockpholmes.bsky.social)

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Wolfgang Huber is a prominent German theologian and ethicist. Huber served as bishop of the Evangelical Church of Berlin-Brandenburg-Silesian Upper Lusatia until November 2009. Huber succeeded Manfred Kock as Chairperson of the Council of the Evangelical Church in Germany (EKD) in November 2003 and was succeeded by Bishop Margot Käßmann, the first woman in that position, in October 2009. .. more

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Wolfgang Huber @wkhuber.bsky.social · Aug 24

In July we had the 3rd edition of the Ukrainian Biological Data Science Summer School.
Now a regular, it has created a sense of community: young people eager to learn new topics, network across the country&world. Seeing how science is a positive&optimistic force.

www.huber.embl.de/group/posts/...

Ukrainian Biological Data Science Summer School 2025 – Huber Group @ EMBL

Uzhhorod, 19 July - 1 August 2025: the third edition

www.huber.embl.de

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Reposted by Simon Roux, Wolfgang Huber, Larry W. Hunter , and 1 more Simon Roux, Wolfgang Huber, Larry W. Hunter, Alan McNally

Ewan Birney @ewanbirney.bsky.social · 1d

I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Staff Scientist

About EMBL-EBI EMBL’s European Bioinformatics Institute is a data powerhouse, utilised on a global scale to advance scientific discovery through bioinformatics and solutions to some of the world’s mos...

embl.wd103.myworkdayjobs.com

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Reposted by Peter Thorne, Carl T. Bergstrom, Gavin A. Schmidt , and 8 more Peter Thorne, Carl T. Bergstrom, Gavin A. Schmidt, Stacie B. Dusetzina, Lesley A. Hall, Margot C. Finn, Zen Faulkes, David Murakami Wood, Wolfgang Huber, Klaus Oschema, Philip Bell

Prof Anna Watts @profannawatts.bsky.social · 1d

Lol the Nobels can't even acknowledge women's contribution to discovery. But sure let's acknowledge The Machines.

Headline from an article in Nature this week that states "Prizes must recognize machine contributions to discovery. The future of science will be written by humans and machines together. Awards should reflect that reality."

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Reposted by Veli‐Matti Karhulahti, Wolfgang Huber

Berna Devezer @devezer.bsky.social · 1d

I believe science is much more like art than many scientists are willing to consider. I have a feeling that it would free us to do better science if we embraced this view. I may be mistaken but that's where I am mentally.

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Wolfgang Huber @wkhuber.bsky.social · 1d

My take: Engineering *is* important. Ideas are cheap. Novelty is overrated. "Hyperparameter tuning" is a cynically dismissive term for something that is in fact the real, difficult problem.

Eugene Vinitsky 🍒 @eugenevinitsky.bsky.social · 1d

Sometimes I’ll see a paper that implements an idea I’ve had but implements it poorly for engineering reasons. But then it’s hard to write a follow up paper because it’s not “novel” anymore

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Reposted by Wolfgang Huber

Eugene Vinitsky 🍒 @eugenevinitsky.bsky.social · 1d

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Wolfgang Huber @wkhuber.bsky.social · 1d

Often, there are trade-offs between making model assumptions and learning from data.

If you have little data, there is no alternative to modelling. And modelling and math are fun. But assumptions may be
unverifiable or esoteric, and with lots of data, you can for some of them just go and "see".

Wolfgang Huber @wkhuber.bsky.social · 2d

Multiple hypothesis testing is easier to understand than single hypothesis testing. Yet it is often taught the wrong way round.

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Reposted by Wolfgang Huber, Larry W. Hunter

Ewan Birney @ewanbirney.bsky.social · 2d

A reminder that the PhD program for EMBL is open for winter recruitment round. If you want to understand life at a molecular level and have a quantitative science (you don't have to have done biology - we love our mathematicians/physcists/chemists!) apply www.embl.org/about/info/e...

Application – EMBL International PhD Programme

www.embl.org

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Reposted by Wolfgang Huber

Jörg Vogel @jorg-vogel-lab.bsky.social · 2d

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

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Reposted by Wolfgang Huber

Our World in Data @ourworldindata.org · 2d

As this chart shows, two centuries ago, about one in three children in Sweden died before they were five years old.

Since then, the child mortality rate in Sweden has declined to 0.3%.

South Korea achieved a similar reduction much faster.

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Reposted by Wolfgang Huber

Inigo Martincorena @imartincorena.bsky.social · 2d

Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...

Somatic mutation and selection at population scale - Nature

A new version of nanorate DNA sequencing, with an error rate lower than five errors per billion base pairs and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection and the generation of high-resolution selection maps across coding and non-coding sites for many genes.

www.nature.com

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Reposted by Wolfgang Huber

Erick Ratamero @erickratamero.com · 3d

Applications are open until 12/10 for both positions, so you might need to hurry :) I think these are both very exciting - and as a bonus (or a malus) your office space would probably be right next door to me!

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Reposted by Wolfgang Huber, Larry W. Hunter

Erick Ratamero @erickratamero.com · 3d

Second, for a Mathematical Modeling Specialist - this person will consult and collaborate in projects, but also engage in training and establishing a community of practice. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Mathematical Modeling Specialist (Life Sciences)

EMBL Data Science Centre meets the growing demand for advanced data analysis at EMBL and ensures that biological research data at our multi-site organisation are expertly processed, integrated, annota...

embl.wd103.myworkdayjobs.com

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Reposted by Wolfgang Huber, Larry W. Hunter

Erick Ratamero @erickratamero.com · 3d

The Data Science team at EMBL is hiring for two open positions! First, for a Scientific Community Manager, focusing on community aspects and training on data science. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Scientific Community Manager

EMBL is Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation with more than 110 independent research groups and teams performing scientific research in disci...

embl.wd103.myworkdayjobs.com

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Reposted by Wolfgang Huber

Karl Schmid @kjschmid.bsky.social · 3d

The Cluster of Excellence @greenrobust.de is hiring:

- Computer Scientist/Research data manager: shorturl.at/xSvvO
- Data steward: shorturl.at/l6NCv
- Scientific coordinator 'Plant Perturbation Atlas': shorturl.at/vBU6x

Deadline: Friday, 7 November 2025

RT are welcome

#plantjobs #plantscijobs

Stellenangebote: Universität Hohenheim

Aktuelle Stellenangebote der Universität Hohenheim.

www.uni-hohenheim.de

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Defend Democracy @defenddemocracy.bsky.social · 6d

President Macron: “Europeans, let's wake up!

We have been incredibly naive in entrusting our democratic space to social networks.”

defenddemocracy.eu/macron-democ...

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Wolfgang Huber @wkhuber.bsky.social · 6d

(Huber lab)[EMBL] welcomes applications for a PhD in ML for spatial omics [representation learning + integration with biostatistics, cell + anatomy foundation models, collaborate with domain scientists on cancer and dev:bio discovery science] |> Apply though the ELLIS portal ::: Deadline 2025-10-31

ELLIS @ellis.eu · 9d

🎓 The application portal for the #ELLISPhD Program is open today! Info & link: https://bit.ly/45DSe75

ELLIS PhD Program: Call for Applications 2025

The ELLIS mission is to create a diverse European network that promotes research excellence and advances breakthroughs in AI, as well as a pan-European PhD program to educate the next generation of AI...

ellis.eu

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Reposted by Nicole Dubilier, Wolfgang Huber

Gautam Dey @gautamdey.bsky.social · 7d

If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.

I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support

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Reposted by Jens Rommel, Wolfgang Huber, Maksym Polyakov

Paul Hünermund @p-hunermund.com · 8d

Post a favorite econ paper: Lichter et al. (2021, JEEA) @sigginho.bsky.social

Regions with higher Stasi spy density in East Germany still show lower trust, lower incomes, higher unemployment, and less entrepreneurship decades after reunification.

Open-access link: doi.org/10.1093/jeea...

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Reposted by Serge Belongie, Wolfgang Huber

ELLIS @ellis.eu · 9d

🎓 The application portal for the #ELLISPhD Program is open today! Info & link: https://bit.ly/45DSe75

ELLIS PhD Program: Call for Applications 2025

ellis.eu

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Reposted by Wolfgang Huber

Achim Zeileis @zeileis.org · 9d

Web access to R-Forge is live again! 🎉

r-forge.r-project.org

R-Forge: Welcome

R-Forge.R-project.org

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Wolfgang Huber @wkhuber.bsky.social · 10d

Exactly! Now that does sound a lot like image segmentation, which can be formulated as simultaneously minimising distances (a) among pixels and (b) among their values (intensities).

Real segmentation algorithms can even do more fancy things, like take into account texture, or use boundary markers.

Wolfgang Huber @wkhuber.bsky.social · 10d

but the commonalities seem big enough to not justify a completely different name and different set of computational methods?

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Wolfgang Huber @wkhuber.bsky.social · 10d

to a metric space (tuples of color intensities or expression levels), such as that distances with a segment (or cluster) in both spaces are simultaneously mimised. I understand that there will be different trade-offs, different useful heuristics etc. depending on application domain and objective,...

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Wolfgang Huber @wkhuber.bsky.social · 10d

Thank you! I agree, but I'd call these differences "marketing"; afaIcs, the underlying maths is the same, and algorithms should to a good extent by transferable?

The common mathematical task being something like: partition a metric manifold (or a lattice graph, etc), based on a function from it...

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Reposted by Mark Alfano, Silvia Secchi, McKenzie Wark , and 2 more Mark Alfano, Silvia Secchi, McKenzie Wark, Wolfgang Huber, Patrick Stokes

Burrito Justice @burritojustice.bsky.social · 10d

quick while the government is shut down let’s all switch to metric

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Wolfgang Huber @wkhuber.bsky.social · 10d

Yes, the remark was tongue-in-cheek of course.
There will always be plenty of work for statisticians to deal with observational data, or experimental data from non-ideal assays and designs.

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