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Jin
@jinnfeng.bsky.social
· May 25
Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight | NEJM
Evidence suggests that incretin-based dual agonist pharmacotherapy is helpful in persons with obesity. Mazdutide, a glucagon-like peptide-1 and glucagon receptor dual agonist, may have efficacy in ...
www.nejm.org
Reposted by Jin
Heiko Lickert
@heikolickert.bsky.social
· Nov 25
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org