@jmoronconcepcion.bsky.social
New study on the role of hippocampal SK2 channels in the encoding and retrieval of morphine-induced associative memories.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Modulation of dorsal hippocampal SK2 channels regulates morphine-enhanced neuronal oscillations and morphine-induced contextual memory encoding and retrieval - Scientific Reports
Persistent maladaptive drug-context associations are a key component of relapse vulnerability and pose a major obstacle in treating opioid use disorder. Although the dorsal hippocampus (dHPC) is criti...
link.springer.com
November 20, 2025 at 1:34 PM
New study on the role of hippocampal SK2 channels in the encoding and retrieval of morphine-induced associative memories.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted
🚨 Please RT!
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
Postdoctoral Research Position
University of California, Los Angeles is hiring. Apply now!
recruit.apo.ucla.edu
October 21, 2025 at 11:44 PM
🚨 Please RT!
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain.
Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged.
Apply 👉 recruit.apo.ucla.edu/JPF10647
#Neuroscience #Postdoc
We published this study a couple of months back but has now been featured by @washumedicine.bsky.social. In this study in collaboration with Bill Carlezon and Domi Burek at McLean we assessed how pain impacts sleep architecture.
source.washu.edu/2025/09/mous...
source.washu.edu/2025/09/mous...
Mouse study links chronic pain to disrupted sleep patterns
Researchers at Washington University in St. Louis School of Medicine have developed the first mouse model to replicate the disrupted sleep patterns seen in people with chronic pain.
source.washu.edu
September 5, 2025 at 1:01 PM
We published this study a couple of months back but has now been featured by @washumedicine.bsky.social. In this study in collaboration with Bill Carlezon and Domi Burek at McLean we assessed how pain impacts sleep architecture.
source.washu.edu/2025/09/mous...
source.washu.edu/2025/09/mous...
New study from the lab on alcohol/pain and taste aversion.
Persistent inflammation does not promote aversion-resistant binge-like #alcohol drinking in rats @jmoronconcepcion.bsky.social #alcoholawareness www.sciencedirect.com/science/arti...
Persistent inflammation does not promote aversion-resistant binge-like alcohol drinking in rats
Chronic pain is a leading cause of disability, significantly decreases quality of life, and is highly co-morbid with substance use disorders, includin…
www.sciencedirect.com
August 30, 2025 at 3:34 AM
New study from the lab on alcohol/pain and taste aversion.
Our new paper on the effects of pain on sleep architecture in collaboration with Bill Carlezon and Erik Musiek is now out at @npp-journal.bsky.social. Work conducted by Domi Burek and Nisa Ibrahim.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Inflammatory pain in mice induces light cycle-dependent effects on sleep architecture - Neuropsychopharmacology
Neuropsychopharmacology - Inflammatory pain in mice induces light cycle-dependent effects on sleep architecture
www.nature.com
June 22, 2025 at 1:02 PM
Our new paper on the effects of pain on sleep architecture in collaboration with Bill Carlezon and Erik Musiek is now out at @npp-journal.bsky.social. Work conducted by Domi Burek and Nisa Ibrahim.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
So honored to have our work highlighted in The Scientist
www.the-scientist.com/female-sex-h...
www.the-scientist.com/female-sex-h...
Female Sex Hormones Reduced Fentanyl Use in Rats
Exploring how sex differences regulate dopamine responses could inform novel interventions to prevent or treat substance use disorders.
www.the-scientist.com
May 14, 2025 at 1:41 PM
So honored to have our work highlighted in The Scientist
www.the-scientist.com/female-sex-h...
www.the-scientist.com/female-sex-h...
Amazing preview written by @docbecca.bsky.social on our latest manuscript on the sex dependent effects of pain on fentanyl intake at @cp-neuron.bsky.social
Just a regular old science post - I was delighted to write the Preview piece to accompany a new paper in Neuron by Jose Morón's lab, which finds estrogen/dopamine interactions can mediate sex differences in pain-driven fentanyl taking. www.sciencedirect.com/science/arti...
An unexpected mediator of pain-driven opioid use in males—estrogen
Men who take opioids to relieve pain are at the highest risk for maladaptive misuse and overdose, but a sex-specific neurobiological link between pain…
www.sciencedirect.com
May 7, 2025 at 7:53 PM
Amazing preview written by @docbecca.bsky.social on our latest manuscript on the sex dependent effects of pain on fentanyl intake at @cp-neuron.bsky.social
Our research on alternative treatments for fentanyl overdoses using peripheral restricted opioid antagonists is highlighted in this podcast by Cambridge University. This work was conducted by the outstanding postdoc Dr Brian Ruyle
www.thenakedscientists.com/articles/int...
www.thenakedscientists.com/articles/int...
Opioid overdose treatment bypasses brain, eases side effects
It may not be necessary to get drugs into the brain to block the lethal effects of a fentanyl overdose...
www.thenakedscientists.com
March 24, 2025 at 3:09 PM
Our research on alternative treatments for fentanyl overdoses using peripheral restricted opioid antagonists is highlighted in this podcast by Cambridge University. This work was conducted by the outstanding postdoc Dr Brian Ruyle
www.thenakedscientists.com/articles/int...
www.thenakedscientists.com/articles/int...
Higher opioid deaths among men may be due to sex hormones, new fentanyl study finds - New York Post
March 12, 2025 at 2:40 AM
Higher opioid deaths among men may be due to sex hormones, new fentanyl study finds - New York Post
Some media coverage of our study on the sex-dependent effects of pain on facilitated opioid intake:
medicine.washu.edu/news/female-...
medicine.washu.edu/news/female-...
Female sex hormone protects against opioid misuse, rat study finds | WashU Medicine
Male – but not female – rats in chronic pain self-administer increasing amounts of fentanyl, which is prevented with estrogen treatment
medicine.washu.edu
March 10, 2025 at 4:38 PM
Some media coverage of our study on the sex-dependent effects of pain on facilitated opioid intake:
medicine.washu.edu/news/female-...
medicine.washu.edu/news/female-...
New work from the lab published at @cp-neuron.bsky.social. In this study we dissect the role of hormonal regulation in pain-induced enhanced opioid intake in males.
Work conducted by the super talented @jessinbotham
www.cell.com/neuron/fullt...
Work conducted by the super talented @jessinbotham
www.cell.com/neuron/fullt...
Estradiol protects against pain-facilitated fentanyl use via suppression of opioid-evoked dopamine activity in males
Higginbotham et al. show that inflammatory pain increases opioid-evoked dopamine neuron
activity to promote fentanyl use selectively in males. Ovarian hormones offer females
protection, but estradiol’...
www.cell.com
March 10, 2025 at 3:54 PM
New work from the lab published at @cp-neuron.bsky.social. In this study we dissect the role of hormonal regulation in pain-induced enhanced opioid intake in males.
Work conducted by the super talented @jessinbotham
www.cell.com/neuron/fullt...
Work conducted by the super talented @jessinbotham
www.cell.com/neuron/fullt...
JMC lab decoration
December 18, 2024 at 10:16 PM
JMC lab decoration
Our new work on the use of peripheral restricted antagonists to prevent and rescue fentanyl induced respiratory depression without unwanted side effects such as aversive behavior is out now! Great work by lead author @brian_ruyle
elifesciences.org/for-the-pres...
elifesciences.org/for-the-pres...
Researchers identify new therapeutic strategy for fentanyl overdose
Blocking peripheral opioid receptors with naloxone methiodide sufficiently prevents and reverses fentanyl-induced cardiorespiratory depression without causing the aversive effects of naloxone in roden...
elifesciences.org
December 10, 2024 at 1:35 PM
Our new work on the use of peripheral restricted antagonists to prevent and rescue fentanyl induced respiratory depression without unwanted side effects such as aversive behavior is out now! Great work by lead author @brian_ruyle
elifesciences.org/for-the-pres...
elifesciences.org/for-the-pres...
Our Neuroprep postbacc program at WashU is now accepting applications. This program offers 2 years of research intensive experience in neuroscience laboratories at WashU to help potential neuroscience graduate student applicants. Please apply now!
neuroprep.wustl.edu
neuroprep.wustl.edu
WashU Neuroprep
Outstanding training to ready scholars for graduate careers in neuroscience
neuroprep.wustl.edu
December 9, 2024 at 5:04 PM
Our Neuroprep postbacc program at WashU is now accepting applications. This program offers 2 years of research intensive experience in neuroscience laboratories at WashU to help potential neuroscience graduate student applicants. Please apply now!
neuroprep.wustl.edu
neuroprep.wustl.edu
Reposted
Heading to my first #ACNP2024 ! Will be sharing the stage with @jmoronconcepcion.bsky.social and @marieeikemo.bsky.social on Sunday 4-4:50pm to discuss Mechanisms Supporting Sex Differences in Opioid Use and Pain: From Preclinical to Clinical Studies.
December 7, 2024 at 4:09 AM
Heading to my first #ACNP2024 ! Will be sharing the stage with @jmoronconcepcion.bsky.social and @marieeikemo.bsky.social on Sunday 4-4:50pm to discuss Mechanisms Supporting Sex Differences in Opioid Use and Pain: From Preclinical to Clinical Studies.
The JMC at WashU aims to dissect the intersection between pain and opioid use disorders to find better therapeutic approaches.
moronconcepcionlab.wustl.edu
moronconcepcionlab.wustl.edu
Moron-Concepcion Lab
A website by WashU Sites
moronconcepcionlab.wustl.edu
November 22, 2024 at 4:17 PM
The JMC at WashU aims to dissect the intersection between pain and opioid use disorders to find better therapeutic approaches.
moronconcepcionlab.wustl.edu
moronconcepcionlab.wustl.edu
Reposted
We’re hiring tenure-track faculty focused on Systems & #ComputationalNeuroscience at the Friedman Brain Institute at Mount Sinai!
We're starting to review applications so submit yours ASAP! 👇
We're starting to review applications so submit yours ASAP! 👇
📢 Calling all Systems & Computational Neuroscience researchers! The #FriedmanBrainInstitute invites applications for full-time, tenure-track faculty position. While application review process begins next week, applications are still being accepted! Apply Now👉 neuroscience.mssm.edu/docs/Faculty...
November 20, 2024 at 8:15 PM
We’re hiring tenure-track faculty focused on Systems & #ComputationalNeuroscience at the Friedman Brain Institute at Mount Sinai!
We're starting to review applications so submit yours ASAP! 👇
We're starting to review applications so submit yours ASAP! 👇