Dr Jolet Mimpen
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joletmimpen.bsky.social
Dr Jolet Mimpen
@joletmimpen.bsky.social
Arthritis UK Foundation Fellow at NDORMS, University of Oxford.

🇳🇱 living in 🇬🇧

Interested in osteoarthritis pathophysiology & tendon biology.
Reposted by Dr Jolet Mimpen
We’ve mapped the Achilles tendon at single-cell resolution 🧬 — revealing 6 fibroblast types with distinct roles across muscle–tendon zones. A new atlas for understanding injury + repair.

Find our more in our new preprint www.biorxiv.org/content/10.1...

#Tendon #CellAtlas #SpatialTranscriptomics
Fibroblast specialisation across microanatomy in a single-cell atlas of healthy human Achilles tendon
Tendons are transitional tissues linking muscle to bone, enabling locomotion and fine motor control. The cellular biology across the Achilles tendon unit is poorly understood, yet critical for interpr...
www.biorxiv.org
October 30, 2025 at 11:18 AM
Reposted by Dr Jolet Mimpen
M. V. Franchi et al. offer this #TranslationalPerspective highlighting new insights into acute tendon molecular reprogramming after rupture based on research by Mimpen et al. (2025)✍️

🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
September 5, 2025 at 2:02 PM
Very excited to see this Translational Perspective by Asst Prof @mvfranchi.bsky.social, Dr Christopher Fry, and Prof Michael Kjaer discussing our recent transcriptomics study on the early injury response in human quadriceps tendons in @jphysiol.bsky.social.
physoc.onlinelibrary.wiley.com
July 21, 2025 at 4:55 PM
Reposted by Dr Jolet Mimpen
If you're interested in the extracellular matrix of soft tissues and the role ECM plays in osteoarthritis then this systematic review is for you!

boneandjoint.org.uk/Article/10.1...
December 3, 2024 at 1:15 PM
It is great to finally share our systematic review on structural extracellular matrix components in soft tissues in osteoarthritis!

Congratulations to my co-authors Iwan Raza and @sarahsnelling.bsky.social.

boneandjoint.org.uk/Article/10.1...
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review | Bone & Joint
Defining the extracellular matrix in non-cartilage soft-tissues in osteoarthritis: a systematic review
boneandjoint.org.uk
December 3, 2024 at 11:36 AM
Wonder what it is like to study at @ndorms.bsky.social at the University of Oxford? Here we share some of our experiences from working in an interdisciplinary team with the wonderful @sarahsnelling.bsky.social.

Please feel free to get in touch if you have any questions!
November 27, 2024 at 11:44 AM