I'm working on a new water-dipping objective targeting expansion imaging. Targeting the following specs:

5mm WD
NA 1.0
1.2mm FOV, plan-corrected
8mm EFL ("25x") but this is flexible
well-corrected in visible
minimum mechanical profile

Optics question: is there any reason to make it telecentric?

The ASI machine shop made a nice replica model of the AMS-AGY v3 objective for us to have in the #CellBio2025 booth. The first of the real ones will be ready by the end of the year.

If you are at #CellBio2025 stop by and say hello at booth 1101

Great to see the ASI single-objective light sheet used for long-term imaging of tumor cells to study the transition between single-cell and multi-cellular spheroids: www.biorxiv.org/content/10.1...

Production has started for a new #Snoutscope objective, AMS-AGY v3. It has significantly larger FOV and some other tweaks from v1 and v2. Currently accepting pre-orders. The price will need to increase modestly after deliveries start late October.

I'm excited to be able to be in Zurich for the mesoSPIM symposium. This is a really fantastic project.

Most high-NA air objective lenses are coverslip-corrected but sometimes you want to image in air, e.g. high-NA SOLS. We have glued coverslips onto objectives for this. To make sure it gets glued properly we take image stack of diffraction-limited beads supported on a coverslip. 🧵

Interested in getting imaging data like this? ASI is commercializing single-objective light sheet microscopes and might make one like DaXi if there are people who would buy it. DaXi originally developed by @loicaroyer.bsky.social and Bin Yang. vimeo.com/801341925