@keithcaldecott.bsky.social
Exciting work from the Rass lab, and colleagues at the GDSC 🥳
My first post on bsky to share our latest research in @nature.com: “DNA2 enables growth by restricting recombination-restarted replication” - defines DNA2’s essential function & elucidates links with primordial dwarfism and cancer. Thanks to the lab, collaborators & @ukri.org @acmedsci.bsky.social
DNA2 enables growth by restricting recombination-restarted replication - Nature
DNA2 suppresses recombination-restarted replication and checkpoint activation at stalled forks, and its loss triggers recombination-dependent synthesis, checkpoint signalling and cell-cycle exit, high...
www.nature.com
September 3, 2025 at 5:10 PM
Exciting work from the Rass lab, and colleagues at the GDSC 🥳
Reposted
Our latest study is out in Nucleic Acids Research. FEN1 is critical for rapid single-strand break repair in G1 phase url: academic.oup.com/nar/article/...
FEN1 is critical for rapid single-strand break repair in G1 phase
Abstract. Flap endonuclease 1 (FEN1)-dependent long-patch repair has been considered a minor sub-pathway of DNA single-strand break repair (SSBR), activate
academic.oup.com
July 28, 2025 at 7:35 AM
Our latest study is out in Nucleic Acids Research. FEN1 is critical for rapid single-strand break repair in G1 phase url: academic.oup.com/nar/article/...
Reposted
🗣️ #WomeninScience at IOCB cordially invite you to the next event in the #DanaHockoválecture series by Dr. Hana Hanzlíková ( #UniBern/ @imgprague.bsky.social @czechacademy.bsky.social).
See more ► www.uochb.cz/en/event-cal... ⤵️
See more ► www.uochb.cz/en/event-cal... ⤵️
July 28, 2025 at 10:04 AM
🗣️ #WomeninScience at IOCB cordially invite you to the next event in the #DanaHockoválecture series by Dr. Hana Hanzlíková ( #UniBern/ @imgprague.bsky.social @czechacademy.bsky.social).
See more ► www.uochb.cz/en/event-cal... ⤵️
See more ► www.uochb.cz/en/event-cal... ⤵️
Reposted
Our latest study is now online! A great collaboration between the @fgh-lab.bsky.social and @enriquedealava.bsky.social Labs, driven by the outstanding work of J. Olmedo-Pelayo at @ibis-investigacion.bsky.social Check it out!
EWS::FLI1-DHX9 interaction promotes Ewing sarcoma sensitivity to DNA topoisomerase 1 poisons by altering R-loop metabolism - Oncogene
Oncogene - EWS::FLI1-DHX9 interaction promotes Ewing sarcoma sensitivity to DNA topoisomerase 1 poisons by altering R-loop metabolism
www.nature.com
July 29, 2025 at 8:36 AM
Our latest study is now online! A great collaboration between the @fgh-lab.bsky.social and @enriquedealava.bsky.social Labs, driven by the outstanding work of J. Olmedo-Pelayo at @ibis-investigacion.bsky.social Check it out!
Dear all,
Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: [email protected]
Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: [email protected]
February 10, 2025 at 2:45 PM
Dear all,
Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: [email protected]
Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: [email protected]
Dear all, over Christmas I was sadly informed that Larry Thompson died on Dec.16th. Those of you that knew Larry and his work will know how big a loss this is to the genome stability community. A brief memoriam and tribute to Larry is available in DNA Repair.
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
January 28, 2025 at 11:40 AM
Dear all, over Christmas I was sadly informed that Larry Thompson died on Dec.16th. Those of you that knew Larry and his work will know how big a loss this is to the genome stability community. A brief memoriam and tribute to Larry is available in DNA Repair.
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
Reposted
The Genome Damage and Stability Centre at the University of Sussex has now joined BlueSky! Follow us here, for news, views and publications.
December 6, 2024 at 9:25 AM
The Genome Damage and Stability Centre at the University of Sussex has now joined BlueSky! Follow us here, for news, views and publications.
This meeting is always very very special…..don’t miss it.
What are your plans for October 2025? It would be a fantastic time to visit Norway for the Endogenous DNA Damage and Repair conference with a stellar set of speaker covering a wide range of topics. www.endodnadamage.com
December 4, 2024 at 6:55 PM
This meeting is always very very special…..don’t miss it.
Dear all, my first post! I have postdoc positions available if you would like to join my lab in beautiful Sussex by the Sea! Please contact me on [email protected]
December 3, 2024 at 11:47 AM
Dear all, my first post! I have postdoc positions available if you would like to join my lab in beautiful Sussex by the Sea! Please contact me on [email protected]