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Kristian Pietras lab @kpietraslab.bsky.social · Jun 4

Don’t miss a joint LUCC-LBIC-ZEISS-ACD seminar on visualization of gene expression and biomarker localization in 2D, 3D and 4D. 16th June, BMC, Lund.

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Reposted by Kristian Pietras lab

Alexander Pietras Lab @pietraslab.bsky.social · May 15

🚨 We’re hiring a bioinformatics-focused PhD student for our ERC-funded project on recurrent GBM! Focus: tumor-supportive microenvironment 🔬 Experience with scRNA-seq, spatial transcriptomics & Python/R a plus. Must be self-motivated & driven. DM for details! Repost=❤️ lu.varbi.com/en/what:job/...

Doctoral Student in Tumor Biology

Description of the workplace The research group conducts experimental research on brain tumors and is led by Associate Professor Alexander Pietras. The group consists of a bioinformatician, two postdo

lu.varbi.com

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Kristian Pietras lab @kpietraslab.bsky.social · May 9

Swedish Childhood Cancer Fund (BCF) is raising awareness and support: today it is #Fotbollströjefredagen (Football shirt Friday)

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Kristian Pietras lab @kpietraslab.bsky.social · Apr 23

Join us for innovative explorations of the tumor microenvironment🔬 Learn cutting-edge technologies and grow in a dynamic environment💡 The postdoc will work alongside a doctoral student from @adaptmet.bsky.social, gaining access to collaborative partners across 🇪🇺.
Apply now👇
tinyurl.com/4mby45hf

Postdoc in Experimental Oncology - Lund (Stad), Skåne (SE) job with Lund University | 12838990

Lunds universitet, 009999 LUNDS UNIVERSITET, 310000 MED Lund University was founded in 1666 and is repeatedly ranked among the world’s top universi...

tinyurl.com

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Reposted by Kristian Pietras lab

Journal of Clinical Investigation @jci.org · Mar 13

Targeting the most immune-suppressive macrophage with ALK1 inhibitors in malignant breast cancer!
@kpietraslab.bsky.social & team @lund-university.bsky.social target the most immune-suppressive macrophage with ALK1 inhibitors in malignant breast cancer models!
buff.ly/FXssb1x

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Kristian Pietras lab @kpietraslab.bsky.social · Mar 10

Congratulations Kristian! @lundsuniversitet.bsky.social @lunduniversity-med.bsky.social

Kristian Pietras lab @kpietraslab.bsky.social · Mar 10

We are proud to share that our PI has been named Cancer Researcher of the Year by @Cancerfonden! This well-deserved recognition highlights not only his outstanding contributions to cancer research but also his creativity in tackling scientific challenges and his inspiring leadership within our team.

Kristian Pietras – Årets cancerforskare 2025

Kristian Pietras forskar om hur celler i blodkärl och bindväv påverkar cancerns möjlighet att växa eller dö. Nu tilldelas han utmärkelsen Årets cancerforskare.

www.cancerfonden.se

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Reposted by Kristian Pietras lab

Adaptmet @adaptmet.bsky.social · Feb 10

🎉 Today, we gathered online for the #AdaptMet Kick-Off Meeting! A fantastic start to this journey, bringing together top researchers & partners to train the next generation of metastasis experts. Exciting discussions & collaborations ahead—stay tuned! 🔬✨ #CancerResearch

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Kristian Pietras lab @kpietraslab.bsky.social · Jan 31

At the Brain Tumor Microenvironment Symposium @institutducerveau.bsky.social, Sebastian Braun presented our comprehensive study of pericytes in GBM 🤩. Pericytes act as guardians of the peri-vascular niche to prevent malignant cell invasion, read more at www.biorxiv.org/content/10.1...

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Kristian Pietras lab @kpietraslab.bsky.social · Jan 23

@jessicapantaleo.bsky.social making us proud at the @lund-university.bsky.social Cancer Centre Tumor Microenvironment retreat by presenting our latest findings on CAF subtype spatial organization across longitudinally sampled experimental breast cancers.

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Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

www.nature.com/articles/s41...

Cancer-associated fibroblasts rewire the estrogen receptor response in luminal breast cancer, enabling estrogen independence - Oncogene

Oncogene - Cancer-associated fibroblasts rewire the estrogen receptor response in luminal breast cancer, enabling estrogen independence

www.nature.com

Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

Thanks @oncogenejournal for highlighting our work on cancer-associated fibroblasts that enable endocrine resistance in luminal breast cancer
www.nature.com/collections/...

Readers Choice: The best of Oncogene 2024

In this collection we highlight a selection of articles from 2024, which top the list of the journal’s most cited, downloaded and most shared (including press ...

www.nature.com

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Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

Finally, we send our gratitude to all funders
@lund-university.bsky.social , @vetenskapsradet.bsky.social @kawresearch.bsky.social, Cancerfonden, Region Skåne, The Göran Gustafsson Foundation, The Mats Paulsson Foundations, Cancera, The Crafoord Foundation, and the Fru Berta Kamprad Foundation.
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Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

Last chance to apply, call closes on Jan 17th!

Kristian Pietras lab @kpietraslab.bsky.social · Nov 18

We are live 🕺! Recruitment for the exciting MSCA doctoral network Adaptmet is now open. Join us and great collaborators across Europe to explore fundamental mechanisms of metastatic dissemination:
adaptmet.eu/recruitment/

Recruitment

Recruitment is now open! Apply for one of the 16 positions availablein the Adaptmet network and build your futureas a researcher in metastasis! Adaptmet is offering generous three-year fellowship...

adaptmet.eu

Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

Incredible skills, knowledge, endurance, passion, and joy went into the making of this study by main authors @matteobocci.bsky.social, Mehrnaz Safaee-Talkhoncheh, and Jonas Sjölund. We also thank all co-authors, and especially acknowledge the work of undergraduate and graduate students.
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Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

Based on our work, the combination of ALK1 inhibition with immune checkpoint blockade is suggested as a rational treatment regimen; clinical studies by pharmaceutical industry provide initial support for this proposition (pmc.ncbi.nlm.nih.gov/articles/PMC...).
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Combination of GT90001 and nivolumab in patients with advanced hepatocellular carcinoma: a multicenter, single-arm, phase 1b/2 study

GT90001 (also known as PF-03446962) is an anti-ALK-1 monoclonal antibody and has shown activity in hepatocellular carcinoma (HCC). This phase 1b/2 study was designed to determine the recommended phase...

pmc.ncbi.nlm.nih.gov

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Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

ALK1 inhibition acted in a multimodal manner to suppress breast cancer metastatic dissemination to the lung by: 1) Interfering with the differentiation and release of monocytes in the bone marrow and 2) Reducing the mobilization of immunosuppressive macrophages across the endothelial barrier.
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Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

When we set out on this journey, we did not expect to delve into tumor immunology, but the unanticipated expression of ALK1 on a subset of highly immunosuppressive macrophages led us to detail a role for ALK1 at the crossroads between tumor angiogenesis and immunity.
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Kristian Pietras lab @kpietraslab.bsky.social · Jan 15

We have been waiting impatiently but can finally share our latest efforts in understanding the biology of the TGF-beta type I receptor ALK1 (gene name ACVRL1), see graphical abstract in post and the full article here: www.jci.org/articles/vie...
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Kristian Pietras lab @kpietraslab.bsky.social · Dec 18

The two Pietras labs @pietraslab.bsky.social @kpietraslab.bsky.social collide in a fierce game of Ping Pong. The losers fill all pipette tip boxes the next year 😜

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Reposted by Kristian Pietras lab

Adaptmet @adaptmet.bsky.social · Dec 10

Kristian Pietras @kpietraslab.bsky.social at Lund University @lunduniversity.bsky.social will oversee DC4 who will work on the suppression of metastatic dissemination through precision targeting of cancer-associated fibroblast niches

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Kristian Pietras lab @kpietraslab.bsky.social · Dec 4

adaptmet.eu

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Kristian Pietras lab @kpietraslab.bsky.social · Dec 4

Come join us and @svanharanta.bsky.social @cedric-blanpain.bsky.social Roger Gomis @irbbarcelona.bsky.social @obenaufa.bsky.social Karin de Visser @nkinl.bsky.social @grauperalab.bsky.social @prat-aleix-md.bsky.social @vickysanzmoreno.bsky.social @johannajoyce.bsky.social @momobentires.bsky.social

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Kristian Pietras lab @kpietraslab.bsky.social · Dec 4

adaptmet.eu