Sze Chai Kwok
@kwokszechai.bsky.social
Cognitive neuroscientist studying memory (lab: http://www.kwoklab.org/), associate prof. Duke Kunshan University.
twitter: https://twitter.com/Kwokszechai
twitter: https://twitter.com/Kwokszechai
Pinned
Coming to SfN at San Diego w/ two poster presentations and a minisymposium talk. chairing the minisymposium on "Representation of Time in the Brain". #SfN @iinzniuono.bsky.social Zhiyong Jin and Xuanlong Zhu.
#SfN25 Mini-symposium: Today at 9:30 am PST | Representation of Time in the Brain
Read the accompanying article by Kwok et al. in #JNeurosci
https://doi.org/10.1523/JNEUROSCI.1397-25.2025
Read the accompanying article by Kwok et al. in #JNeurosci
https://doi.org/10.1523/JNEUROSCI.1397-25.2025
November 19, 2025 at 3:45 PM
Reposted by Sze Chai Kwok
For those coming to SfN, I’ll be giving a talk showing evidence of hippocampal neuronal replay 🎞️🔁 in HUMANS as part of the “Representation of Time in the Brain” minisymposium (Wednesday morning)
Our stellar group of speakers also wrote a preview of the session in @sfnjournals.bsky.social #sfn2025
🧠
Our stellar group of speakers also wrote a preview of the session in @sfnjournals.bsky.social #sfn2025
🧠
Neural Representation of Episodic Time
Inspired by recent discoveries of neural populations that track time for specific moments (time cells) and elapsed durations (temporal context and periodic time cells), this review, based on a minisym...
www.jneurosci.org
November 15, 2025 at 7:15 PM
For those coming to SfN, I’ll be giving a talk showing evidence of hippocampal neuronal replay 🎞️🔁 in HUMANS as part of the “Representation of Time in the Brain” minisymposium (Wednesday morning)
Our stellar group of speakers also wrote a preview of the session in @sfnjournals.bsky.social #sfn2025
🧠
Our stellar group of speakers also wrote a preview of the session in @sfnjournals.bsky.social #sfn2025
🧠
Coming to SfN at San Diego w/ two poster presentations and a minisymposium talk. chairing the minisymposium on "Representation of Time in the Brain". #SfN @iinzniuono.bsky.social Zhiyong Jin and Xuanlong Zhu.
November 13, 2025 at 5:47 PM
Coming to SfN at San Diego w/ two poster presentations and a minisymposium talk. chairing the minisymposium on "Representation of Time in the Brain". #SfN @iinzniuono.bsky.social Zhiyong Jin and Xuanlong Zhu.
Reposted by Sze Chai Kwok
Last month, I launched my lab at Ohio State. Our lab website is now live, and we're recruiting graduate students this cycle! If you're interested in the cognitive (neuro)science of learning & memory, please reach out!
www.momentslab.org
www.momentslab.org
Moments Lab
www.momentslab.org
September 19, 2025 at 2:25 PM
Last month, I launched my lab at Ohio State. Our lab website is now live, and we're recruiting graduate students this cycle! If you're interested in the cognitive (neuro)science of learning & memory, please reach out!
www.momentslab.org
www.momentslab.org
Reposted by Sze Chai Kwok
New book— just got my copy! I know people often don’t read book chapters but I think that’s a mistake. They are usually much more reflective and wide ranging than journal articles.
September 16, 2025 at 10:20 PM
New book— just got my copy! I know people often don’t read book chapters but I think that’s a mistake. They are usually much more reflective and wide ranging than journal articles.
Reposted by Sze Chai Kwok
#JNeurosci: Jiang, Cai, Santos-Pata, �€ª@kwokszechai.bsky.social et al. found that hippocampal theta oscillation in humans is modulated by repeated experiences, which in turn increases the efficacy of backward-cued memory retrieval of temporal order.
https://doi.org/10.1523/JNEUROSCI.1223-23.2025
August 30, 2025 at 12:12 PM
#JNeurosci: Jiang, Cai, Santos-Pata, �€ª@kwokszechai.bsky.social et al. found that hippocampal theta oscillation in humans is modulated by repeated experiences, which in turn increases the efficacy of backward-cued memory retrieval of temporal order.
https://doi.org/10.1523/JNEUROSCI.1223-23.2025
Reposted by Sze Chai Kwok
Key-value memory network can learn to represent event memories by their causal relations to support event cognition!
Congrats to @hayoungsong.bsky.social on this exciting paper! So fun to be involved!
Congrats to @hayoungsong.bsky.social on this exciting paper! So fun to be involved!
How does the brain🧠 make causal inferences and use memories to understand narratives🎬?
We built an RNN🤖 with key-value episodic memory that learns causal relationships between events and retrieves memories like humans do!
Preprint www.biorxiv.org/content/10.1...
w/ @qlu.bsky.social, Tan Nguyen &👇
We built an RNN🤖 with key-value episodic memory that learns causal relationships between events and retrieves memories like humans do!
Preprint www.biorxiv.org/content/10.1...
w/ @qlu.bsky.social, Tan Nguyen &👇
A neural network with episodic memory learns causal relationships between narrative events
Humans reflect on past memories to make sense of an ongoing event. Past work has shown that people retrieve causally related past events during comprehension, but the exact process by which this causa...
www.biorxiv.org
September 5, 2025 at 1:07 PM
Key-value memory network can learn to represent event memories by their causal relations to support event cognition!
Congrats to @hayoungsong.bsky.social on this exciting paper! So fun to be involved!
Congrats to @hayoungsong.bsky.social on this exciting paper! So fun to be involved!
actually led by people at #DukeKunshanUniversity
#JNeurosci: Jiang, Cai, Santos-Pata, �€ª@kwokszechai.bsky.social et al. found that hippocampal theta oscillation in humans is modulated by repeated experiences, which in turn increases the efficacy of backward-cued memory retrieval of temporal order.
https://doi.org/10.1523/JNEUROSCI.1223-23.2025
September 3, 2025 at 10:18 AM
actually led by people at #DukeKunshanUniversity
Reposted by Sze Chai Kwok
Lucas Tian arguing for the invariance, categorical structure, and recombination of motor primitives in macaque prefrontal cortex. www.youtube.com/live/Y8Ke6HC... 3/4
April 3, 2025 at 1:18 PM
Lucas Tian arguing for the invariance, categorical structure, and recombination of motor primitives in macaque prefrontal cortex. www.youtube.com/live/Y8Ke6HC... 3/4
Reposted by Sze Chai Kwok
The next keynote is by Anna Schapiro on "Learning representations of specifics and generalities over time" at 4:30pm today!
📺 Watch live: hva-uva.cloud.panopto.eu/Panopto/Page...
📺 Watch live: hva-uva.cloud.panopto.eu/Panopto/Page...
August 12, 2025 at 2:18 PM
The next keynote is by Anna Schapiro on "Learning representations of specifics and generalities over time" at 4:30pm today!
📺 Watch live: hva-uva.cloud.panopto.eu/Panopto/Page...
📺 Watch live: hva-uva.cloud.panopto.eu/Panopto/Page...
Reposted by Sze Chai Kwok
Your brain doesn’t just passively track time ⏳ - it structures it.
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
www.science.org
June 26, 2025 at 6:06 PM
Your brain doesn’t just passively track time ⏳ - it structures it.
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2)
👉 www.science.org/doi/10.1126/...
Reposted by Sze Chai Kwok
Last week to apply...
Please share; My lab at @psychologyuea.bsky.social @uniofeastanglia.bsky.social is recruiting a post-doc for a cognitive neuroscience memory project. It is a 3-year post, with a proposed start date of 8th September. Application deadline is 15th of June.
vacancies.uea.ac.uk/vacancies/15...
vacancies.uea.ac.uk/vacancies/15...
Senior Research Associate (RA2312) in University of East Anglia | UEA
View details and apply for this Senior Research Associate (RA2312) vacancy in University of East Anglia. School of Psychology
Faculty of Social Sciences
Senior Research Associate
Ref: RA...
vacancies.uea.ac.uk
June 9, 2025 at 10:31 AM
Last week to apply...
in case you or your mentees wanted to join this linking group for a nanosymposium, below are the details: GoldGreen (Linking group), I.07.d Episodic and episodic-like memory (as first level). #sfn @SfNJournals @SfNtweets #neuroscience #memory
June 5, 2025 at 2:06 PM
in case you or your mentees wanted to join this linking group for a nanosymposium, below are the details: GoldGreen (Linking group), I.07.d Episodic and episodic-like memory (as first level). #sfn @SfNJournals @SfNtweets #neuroscience #memory
Reposted by Sze Chai Kwok
🧠🧠Announcing: Neural computations without borders 🧠🧠
So many students and postdocs are stuck due to visa, or other hurdles. To help in a small way, I will mentor about ten students/postdocs in neural computation, or neuro-AI projects, leading to publication/s.
So many students and postdocs are stuck due to visa, or other hurdles. To help in a small way, I will mentor about ten students/postdocs in neural computation, or neuro-AI projects, leading to publication/s.
June 3, 2025 at 3:33 PM
🧠🧠Announcing: Neural computations without borders 🧠🧠
So many students and postdocs are stuck due to visa, or other hurdles. To help in a small way, I will mentor about ten students/postdocs in neural computation, or neuro-AI projects, leading to publication/s.
So many students and postdocs are stuck due to visa, or other hurdles. To help in a small way, I will mentor about ten students/postdocs in neural computation, or neuro-AI projects, leading to publication/s.
Sustained hippocampal theta-oscillations reflect experience-dependent learning in backward temporal order memory retrieval. Now published in the Journal of Neuroscience @SfNtweets , open access: t.co/2b2tN6aeLT #hippocampus #episodicmemory #temporalorder
https://www.jneurosci.org/content/early/2025/05/26/JNEUROSCI.1223-23.2025
t.co
June 3, 2025 at 1:34 PM
Sustained hippocampal theta-oscillations reflect experience-dependent learning in backward temporal order memory retrieval. Now published in the Journal of Neuroscience @SfNtweets , open access: t.co/2b2tN6aeLT #hippocampus #episodicmemory #temporalorder
Reposted by Sze Chai Kwok
Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation.
rdcu.be/el18q
A short thread follows for those interested.
1/n
rdcu.be/el18q
A short thread follows for those interested.
1/n
Systems consolidation reorganizes hippocampal engram circuitry
Nature - A study shows that loss of memory precision associated with systems consolidation can be explained by neurogenesis-dependent reorganization of engram circuitry within the hippocampus over...
rdcu.be
May 14, 2025 at 4:32 PM
Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation.
rdcu.be/el18q
A short thread follows for those interested.
1/n
rdcu.be/el18q
A short thread follows for those interested.
1/n
Reposted by Sze Chai Kwok
Nature Neuroscience
Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks
www.nature.com/articles/s41...
Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks
www.nature.com/articles/s41...
Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks - Nature Neuroscience
The temporal order of events in working memory is thought to be reflected by ordered neuronal firing at different phases. Here the authors show that this is not the case and that phase order is linked...
www.nature.com
March 28, 2025 at 2:17 PM
Nature Neuroscience
Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks
www.nature.com/articles/s41...
Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks
www.nature.com/articles/s41...
Reposted by Sze Chai Kwok
Two cool papers out in Neuron today on memory.
1. Animals can be trained to activate specific remote memories at will:
www.cell.com/neuron/fullt...
2. Interactions between cortex and amygdala during reactivation in NREM sleep help enhance perceptual memories:
www.cell.com/neuron/fullt...
🧠📈 🧪
1. Animals can be trained to activate specific remote memories at will:
www.cell.com/neuron/fullt...
2. Interactions between cortex and amygdala during reactivation in NREM sleep help enhance perceptual memories:
www.cell.com/neuron/fullt...
🧠📈 🧪
Closed-loop modulation of remote hippocampal representations with neurofeedback
Animal models of memory retrieval trigger retrieval with cues and measure retrieval
using behavior. Coulter et al. developed a neurofeedback paradigm that rewards hippocampal
activity patterns associa...
www.cell.com
March 20, 2025 at 3:12 PM
Two cool papers out in Neuron today on memory.
1. Animals can be trained to activate specific remote memories at will:
www.cell.com/neuron/fullt...
2. Interactions between cortex and amygdala during reactivation in NREM sleep help enhance perceptual memories:
www.cell.com/neuron/fullt...
🧠📈 🧪
1. Animals can be trained to activate specific remote memories at will:
www.cell.com/neuron/fullt...
2. Interactions between cortex and amygdala during reactivation in NREM sleep help enhance perceptual memories:
www.cell.com/neuron/fullt...
🧠📈 🧪
Reposted by Sze Chai Kwok
Multiple maps in the hippocampus:
www.cell.com/neuron/abstr...
www.cell.com/neuron/abstr...
Cell-type-specific manifold analysis discloses independent geometric transformations in the hippocampal spatial code
Esparza et al. use cell-type-specific imaging and chemogenetics in freely moving mice
to uncover distinct geometric and topological features of CA1 population activity
during spatial navigation. Their...
www.cell.com
February 27, 2025 at 11:10 PM
Multiple maps in the hippocampus:
www.cell.com/neuron/abstr...
www.cell.com/neuron/abstr...
i am recruiting, w/ Shu Kit Eric Tam mp.weixin.qq.com/s/ygwpJCIqyp...
招聘｜昆山杜克大学郭思齐（认知神经科学教授）、谭树杰（神经科学助理教授）招聘 博士后1名及研究助理2名
mp.weixin.qq.com
February 19, 2025 at 1:53 PM
i am recruiting, w/ Shu Kit Eric Tam mp.weixin.qq.com/s/ygwpJCIqyp...
Spring Round of Hiring at Duke Kunshan University @DukeKunshan, with various positions including 2 in behavioral sciences: t.co/XNd5AzW6qp
t.co/8cfZo7z8so
t.co/8cfZo7z8so
https://academicjobsonline.org/ajo/jobs/29609
t.co
February 8, 2025 at 9:18 AM
Spring Round of Hiring at Duke Kunshan University @DukeKunshan, with various positions including 2 in behavioral sciences: t.co/XNd5AzW6qp
t.co/8cfZo7z8so
t.co/8cfZo7z8so
Reposted by Sze Chai Kwok
Why does it feel good to be sure? In new work @voalan.bsky.social @andero.bsky.social and I bridge confidence and affect. In perceptual DM, we found a remarkably consistent association between both measures! ↓↓↓
link: www.tandfonline.com/doi/full/10....
#PsychSciSky #Neuroscience #Neuroskyence
link: www.tandfonline.com/doi/full/10....
#PsychSciSky #Neuroscience #Neuroskyence
Metacognitive confidence and affect – two sides of the same coin?
Decision confidence is a prototypical metacognitive representation that is thought to approximate the probability that a decision is correct. The perception of being correct has also been associate...
www.tandfonline.com
January 20, 2025 at 4:00 PM
Why does it feel good to be sure? In new work @voalan.bsky.social @andero.bsky.social and I bridge confidence and affect. In perceptual DM, we found a remarkably consistent association between both measures! ↓↓↓
link: www.tandfonline.com/doi/full/10....
#PsychSciSky #Neuroscience #Neuroskyence
link: www.tandfonline.com/doi/full/10....
#PsychSciSky #Neuroscience #Neuroskyence
Reposted by Sze Chai Kwok
🎈New paper🎈 Led by the inimitable @asieh.bsky.social Hippocampal dysfunction in medication naive patients with schizophrenia during a memory task resolves with drug treatment. Incredible team effort! urldefense.proofpoint.com/v2/url?u=htt...
Impaired hippocampal circuitry and memory dysfunction in schizophrenia
Nature Mental Health - Dysfunction in the hippocampal circuitry in individuals with first-episode schizophrenia and delusions is linked to deficits in behavioral pattern separation and recognition...
urldefense.proofpoint.com
January 15, 2025 at 11:05 PM
🎈New paper🎈 Led by the inimitable @asieh.bsky.social Hippocampal dysfunction in medication naive patients with schizophrenia during a memory task resolves with drug treatment. Incredible team effort! urldefense.proofpoint.com/v2/url?u=htt...
Reposted by Sze Chai Kwok
Human hippocampal and entorhinal neurons encode the temporal structure of experience.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Human hippocampal and entorhinal neurons encode the temporal structure of experience - Nature
Single-neuron recordings from intracranial electrodes inserted into human brains for clinical reasons suggest that the temporal structure of human experience is encoded in human hippocampal and entorh...
www.nature.com
November 28, 2024 at 2:42 PM
Human hippocampal and entorhinal neurons encode the temporal structure of experience.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Sze Chai Kwok
A wonderful paper from @tonyzador.bsky.social and colleagues: Encoding innate ability through a genomic bottleneck www.pnas.org/doi/10.1073/...
Encoding innate ability through a genomic bottleneck | PNAS
Animals are born with extensive innate behavioral capabilities, which arise from neural
circuits encoded in the genome. However, the information ca...
www.pnas.org
November 28, 2024 at 9:57 AM
A wonderful paper from @tonyzador.bsky.social and colleagues: Encoding innate ability through a genomic bottleneck www.pnas.org/doi/10.1073/...