lsoucek.bsky.social
@lsoucek.bsky.social
New review just out in Frontiers in Immunology! 🎉

We dive into how #MYC reshapes the tumor–immune interface to drive #immuneescape and resistance to #immunotherapy.
Open access here 👉 www.frontiersin.org/journals/imm...
@vhio.bsky.social @icreacommunity.bsky.social @lsouceklab.bsky.social #peptomyc
Frontiers | MYC at the tumor–immune interface: mechanisms of immune escape and immunotherapy resistance
Immunotherapies have transformed cancer treatment by harnessing the immune system to recognize and eliminate malignant cells, offering durable clinical benef...
www.frontiersin.org
January 23, 2026 at 11:41 AM
Last week in San Francisco was intense, productive, and personally meaningful.

As CSO of #Peptomyc, , I joined our CEO @jesusmartingarcia.bsky.social during #JPMHealthcare week to meet with pharmaceutical companies and discuss potential strategic collaborations.
📍 San Francisco
January 18, 2026 at 10:32 AM
Reposted
We are hiring! If you are interested in joining our Models of Cancer Therapy Laboratory lab at @vhio.bsky.social as a Research Laboratory Technician / Lab Manager, apply here: jobs.vhio.net/en/jobs/7018...
2026-002-01 Research Laboratory Technician / Lab Manager - VHIO
Under the leadership of Josep Tabernero, VHIO is an internationally recognized cancer center. Its multidisciplinary, collaborative model drives scientific progress and innovative cancer treatments.
jobs.vhio.net
January 11, 2026 at 2:04 PM
Really happy to share our new open-access review in Frontiers in Cell and Developmental Biology 🎉
#MYC inhibition creates vulnerabilities that can be targeted with #DDR inhibitors.
@vhio.bsky.social @icreacommunity.bsky.social #peptomyc @lsouceklab.bsky.social
www.frontiersin.org/journals/cel...
Frontiers | The leading role of MYC in DNA damage response: exploring opportunities for therapeutic inhibition
MYC performs a dual role in DNA Damage Response (DDR), promoting genomic instability through replication stress, R-loop formation, and topoisomerase-mediated...
www.frontiersin.org
January 5, 2026 at 10:59 AM
Honored to deliver a keynote today at the 19th Scientific Day & 29th Annual Conference of Vall d’Hebron on collaborative, challenge-driven research with transformative health impact. #MYC #OMO-103 #Omomyc
@vhio.bsky.social @icreacommunity.bsky.social #peptomyc
December 4, 2025 at 7:56 PM
Ayer, 3 de diciembre, participé como ponente en la XV edición del @cniostopcancer.bsky.social Lab Day, contando mi experiencia científica y emprendedora en @vhio.bsky.social, @icreacommunity.bsky.social y #Peptomyc. Muchas gracias a los estudiantes por invitarme! @msmelanoma.bsky.social
December 4, 2025 at 7:51 PM
Our work MYC inhibition by Omomyc causes DNA damage and overcomes PARPi resistance in breast cancer has been accepted in
@cp-cellreports.bsky.social : 🚀
December 3, 2025 at 6:56 AM
Encantada de participar en el Ennova Health Day representando a @vhio.bsky.social, @icreacommunity.bsky.social y #Peptomyc. Gracias a la organización, #DiarioMédico y a los colegas de mesa por un debate inspirador. La innovación nace en y para el hospital.
November 19, 2025 at 8:02 PM
Encantada de participar en el Ennova Health Day representando a @vhio.bsky.social, @icreacommunity.bsky.social y #Peptomyc. Gracias a la organización, #DiarioMédico y a los colegas de mesa por un debate inspirador. La innovación nace en y para el hospital.
November 19, 2025 at 8:00 PM
Mil gracias a la @fundacionfero.bsky.social por su invitación a impartir una Charla Científica en el Circulo Ecuestre y contar el desarrollo de nuestra terapia para el tratamiento del cáncer.
🙏🏻 Gracias FERO por vuestro apoyo continuo a la investigación contra el cáncer! @vhio.bsky.social #peptomyc
October 18, 2025 at 8:42 AM
Este lunes, a las 19:00, tendré el placer de dar una charla para la @fundacionfero.bsky.social en el Círculo Ecuestre en Barcelona , contando el viaje que recorrió nuestro fármaco desde el laboratorio hasta los ensayos clínicos.
Para registrarte: [email protected]
October 11, 2025 at 12:35 PM
Honored to give the closing talk at the inaugural #GordonResearchConference (#GRC) on #Microproteins tomorrow in Castelldefels, Spain. Excited to share our latest work on developing a clinically viable MYC inhibitor and wrap up an incredible week of cutting-edge science. @vhio.bsky.social #peptomyc
August 20, 2025 at 9:07 AM
We are delighted to share that our review “MYC in cancer: from undruggable target to clinical trials” is finally out in Nature Reviews Drug Discovery. What an amazing journey this has been and still promises to be! Big thanks to co-author Jonathan Whitfield. @vhio.bsky.social
rdcu.be/eawOK
MYC in cancer: from undruggable target to clinical trials
Nature Reviews Drug Discovery - Oncogene MYC has been considered ‘undruggable’ for many decades. This Review provides an overview of the various strategies to inhibit MYC, focusing on...
rdcu.be
February 19, 2025 at 8:33 PM