LightNews
lucavalenti.bsky.social
@lucavalenti.bsky.social
83 followers 13 following 1 posts
Posts Media Videos Starter Packs
Reposted
leonardlloyd.bsky.social
Leonard Lloyd @leonardlloyd.bsky.social · Sep 3
250 4.5K 25K
lucavalenti.bsky.social
lucavalenti.bsky.social @lucavalenti.bsky.social · Aug 23
A short overview of the PNPLA3 research field and of the new Liver International Special Issue! Fifteen Years of PNPLA3: Transforming Hepatology Through Human Genetics @stefano-romeo.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
Fifteen Years of PNPLA3: Transforming Hepatology Through Human Genetics
Steatotic liver disease (SLD), caused by excess lipid accumulation in hepatocytes, is now a leading global liver condition triggered by metabolic dysfunction, alcohol, toxins and heritable factors. T....
onlinelibrary.wiley.com
1 3
Reposted
nejm.org
NEJM.org @nejm.org · Aug 13
MASLD has become the most common chronic liver disease worldwide. The authors review the features of the disease as well as pharmacotherapies targeting the associated liver and cardiovascular–renal–metabolic issues. Learn more: nej.md/4lpS4F0

#MedSky #Nephrology
Review Article Metabolic Dysfunction–Associated Steatotic Liver Disease Giovanni Targher, M.D., Luca Valenti, M.D., and Christopher D. Byrne, M.B., Ch.B. Panel A: Factors related to insulin resistance and metabolic dysfunction, diet and environmental exposures, and genetic and epigenetic factors are the main drivers of MASLD development and its progression throughout the entire spectrum of liver disease. Panel B: Female sex and hormonal factors can also modulate the development and progression of MASLD.
5 15