L Brielmaier
@lynnbr2.bsky.social
Electronics Engineer who has ALS. Member IEEE Brain, EMBS,iBCI-CC.org.
Designed & built a custom AAC eye gaze computer.
BCI candidate to drive my exoskeleton. Python & CoPilot noob.
Interested in EAPs. #MedSky
Designed & built a custom AAC eye gaze computer.
BCI candidate to drive my exoskeleton. Python & CoPilot noob.
Interested in EAPs. #MedSky
Pinned
L Brielmaier
@lynnbr2.bsky.social
· Nov 30
For those wishing to slash government medical research spending:
"Just because our lives are finite, doesn’t mean that they’re worthless.”
Ben Strauss
"Just because our lives are finite, doesn’t mean that they’re worthless.”
Ben Strauss
New FDA guidance that’s a ‘huge deal’ for clinical trials www.pharmavoice.com/news/new-fda... via @PharmaVoice
The FDA is currently accepting comments on the draft guidance until March 13.
The FDA is currently accepting comments on the draft guidance until March 13.
New FDA guidance that’s a ‘huge deal’ for clinical trials
Why using Bayesian statistics could transform trial design for rare diseases and beyond.
www.pharmavoice.com
February 18, 2026 at 5:30 PM
New FDA guidance that’s a ‘huge deal’ for clinical trials www.pharmavoice.com/news/new-fda... via @PharmaVoice
The FDA is currently accepting comments on the draft guidance until March 13.
The FDA is currently accepting comments on the draft guidance until March 13.
Reposted by L Brielmaier
Doctors only sit down when they’re about to ruin your day.
February 18, 2026 at 3:43 PM
Doctors only sit down when they’re about to ruin your day.
Pharma could be on the cusp of finally breaking the blood-brain barrier www.pharmavoice.com/news/blood-b... via @PharmaVoice
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
Pharma could be on the cusp of finally breaking the blood-brain barrier
Denali’s brain shuttle technology is poised for a potential landmark approval in April, and other options are gaining ground.
www.pharmavoice.com
February 18, 2026 at 4:46 PM
Pharma could be on the cusp of finally breaking the blood-brain barrier www.pharmavoice.com/news/blood-b... via @PharmaVoice
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
Pharma could be on the cusp of finally breaking the blood-brain barrier www.pharmavoice.com/news/blood-b...
via @PharmaVoice
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
via @PharmaVoice
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
Pharma could be on the cusp of finally breaking the blood-brain barrier
Denali’s brain shuttle technology is poised for a potential landmark approval in April, and other options are gaining ground.
www.pharmavoice.com
February 18, 2026 at 4:44 PM
Pharma could be on the cusp of finally breaking the blood-brain barrier www.pharmavoice.com/news/blood-b...
via @PharmaVoice
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
via @PharmaVoice
the BBB, which protects the brain from viral and bacterial invaders, also repels an estimated 98% of drugs.
I can tolerate algebra, maybe even a little calculus.
But geometry is where I draw the line.
But geometry is where I draw the line.
February 15, 2026 at 10:29 PM
I can tolerate algebra, maybe even a little calculus.
But geometry is where I draw the line.
But geometry is where I draw the line.
February 13, 2026 at 1:38 AM
Trump voters, gun owners, and Republicans began publicly turning on ICE as the Second Amendment hypocrisy collapsed and people realized, “If this happened to him, it could happen to me.”
January 27, 2026 at 1:15 AM
Trump voters, gun owners, and Republicans began publicly turning on ICE as the Second Amendment hypocrisy collapsed and people realized, “If this happened to him, it could happen to me.”
White House Wobbles, Distancing Trump From Initial Response to Minnesota Killing www.nytimes.com/2026/01/26/u...
He was licensed to carry a gun in Minnesota, but video from several angles shows he never pulled one, and his hands were visible as he was shot in the back.
He was licensed to carry a gun in Minnesota, but video from several angles shows he never pulled one, and his hands were visible as he was shot in the back.
White House Wobbles, Distancing Trump From Initial Response to Minnesota Killing
www.nytimes.com
January 26, 2026 at 11:01 PM
White House Wobbles, Distancing Trump From Initial Response to Minnesota Killing www.nytimes.com/2026/01/26/u...
He was licensed to carry a gun in Minnesota, but video from several angles shows he never pulled one, and his hands were visible as he was shot in the back.
He was licensed to carry a gun in Minnesota, but video from several angles shows he never pulled one, and his hands were visible as he was shot in the back.
Congress Pressed on NIH Neurology Leadership Change www.medpagetoday.com/neurology/ge...
Congress has not weighed in on HHS's plan to eliminate NINDS as a stand alone institution.
Congress has not weighed in on HHS's plan to eliminate NINDS as a stand alone institution.
Congress Pressed on NIH Neurology Leadership Change
Losing NINDS director threatens research momentum, AAN says
www.medpagetoday.com
January 23, 2026 at 10:01 PM
Congress Pressed on NIH Neurology Leadership Change www.medpagetoday.com/neurology/ge...
Congress has not weighed in on HHS's plan to eliminate NINDS as a stand alone institution.
Congress has not weighed in on HHS's plan to eliminate NINDS as a stand alone institution.
Schrödinger’s cat just got bigger: quantum physicists create largest ever ‘superposition’ www.nature.com/articles/d41...
Schrödinger’s cat just got bigger: quantum physicists create largest ever ‘superposition’
Record-breaking experiment shows that a cluster of thousands of atoms can act like a wave as well as a particle.
www.nature.com
January 22, 2026 at 4:27 PM
Schrödinger’s cat just got bigger: quantum physicists create largest ever ‘superposition’ www.nature.com/articles/d41...
“There is no such thing as foreigners transferring wealth to the U.S. in the form of tariffs,”
www.wsj.com/economy/trad...
gift article
www.wsj.com/economy/trad...
gift article
Americans Are the Ones Paying for Tariffs, Study Finds
New research contradicts President Trump’s claim that foreigners are footing the bill.
www.wsj.com
January 20, 2026 at 1:15 AM
“There is no such thing as foreigners transferring wealth to the U.S. in the form of tariffs,”
www.wsj.com/economy/trad...
gift article
www.wsj.com/economy/trad...
gift article
Scientists are inventing treatments for devastating diseases. There’s just one problem.
wapo.st/3LoxgBS
wapo.st/3LoxgBS
Scientists are inventing treatments for devastating diseases. There’s just one problem.
Gene therapy treatments for rare diseases are being developed, but getting them out of the lab has proved challenging.
wapo.st
January 11, 2026 at 5:25 PM
Scientists are inventing treatments for devastating diseases. There’s just one problem.
wapo.st/3LoxgBS
wapo.st/3LoxgBS
This week, the Senate Appropriations Committee released a bipartisan package of bills that largely scraps Mr. Trump’s planned cuts.
www.nytimes.com/2026/01/10/s...
www.nytimes.com/2026/01/10/s...
Congress Is Reversing Trump’s Steep Budget Cuts to Science
www.nytimes.com
January 11, 2026 at 3:27 AM
This week, the Senate Appropriations Committee released a bipartisan package of bills that largely scraps Mr. Trump’s planned cuts.
www.nytimes.com/2026/01/10/s...
www.nytimes.com/2026/01/10/s...
Artificial intelligence begins prescribing medications in Utah
Pilot program will test how far patients and regulators are willing to trust AI in medicine.
Pilot program will test how far patients and regulators are willing to trust AI in medicine.
January 7, 2026 at 5:00 PM
Artificial intelligence begins prescribing medications in Utah
Pilot program will test how far patients and regulators are willing to trust AI in medicine.
Pilot program will test how far patients and regulators are willing to trust AI in medicine.
2026 Chevrolet Corvette C8 Stingray revamps cockpit, keeps its blue-collar supercar appeal www.msn.com/en-us/autos/...
The Roar before the Rolex is January 16th.
The Roar before the Rolex is January 16th.
MSN
www.msn.com
January 4, 2026 at 7:47 PM
2026 Chevrolet Corvette C8 Stingray revamps cockpit, keeps its blue-collar supercar appeal www.msn.com/en-us/autos/...
The Roar before the Rolex is January 16th.
The Roar before the Rolex is January 16th.
What we learned about microplastics in 2025 wapo.st/494jpcW
Microplastics are accumulating in the brain!
Microplastics are accumulating in the brain!
What we learned about microplastics in 2025
The year has been full of scary details about the tiny particles. Here’s what we know now.
wapo.st
January 4, 2026 at 1:28 PM
What we learned about microplastics in 2025 wapo.st/494jpcW
Microplastics are accumulating in the brain!
Microplastics are accumulating in the brain!
Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2026/01/02/c...
This is a SCANDAL
This is a SCANDAL
A Study Is Retracted, Renewing Concerns About the Weedkiller Roundup
www.nytimes.com
January 3, 2026 at 12:18 AM
Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2026/01/02/c...
This is a SCANDAL
This is a SCANDAL
Eric Dane now in 24/7 hour care amid ALS diagnosis as estranged wife Rebecca Gayheart shares health update
www.yahoo.com/entertainmen...
via @@Yahoo
www.yahoo.com/entertainmen...
via @@Yahoo
Eric Dane now in 24/7 hour care amid ALS diagnosis as estranged wife Rebecca Gayheart shares health update
Gayheart initially filed for divorce in 2018 from the ‘Grey’s Anatomy’ star, but later dismissed it to support him after his aggressive ALS diagnosis
www.yahoo.com
December 29, 2025 at 11:19 PM
Eric Dane now in 24/7 hour care amid ALS diagnosis as estranged wife Rebecca Gayheart shares health update
www.yahoo.com/entertainmen...
via @@Yahoo
www.yahoo.com/entertainmen...
via @@Yahoo
Reposted by L Brielmaier
It was cold and rainy, yet it was a beautiful Christmas Day.
December 25, 2025 at 4:36 PM
It was cold and rainy, yet it was a beautiful Christmas Day.
Reposted by L Brielmaier
Try regifting your chronic illness.
December 25, 2025 at 4:47 PM
Try regifting your chronic illness.
Long-Term Tofersen Use May Slow ALS Progression, 3-Year Data Suggest www.medpagetoday.com/neurology/ge...
"For people with the SOD1 genetic form of ALS, these results are incredibly hopeful, documenting a substantial effect on slowing this particular form of ALS," Miller told MedPage Today.
"For people with the SOD1 genetic form of ALS, these results are incredibly hopeful, documenting a substantial effect on slowing this particular form of ALS," Miller told MedPage Today.
Long-Term Tofersen Use May Slow ALS Progression, 3-Year Data Suggest
Some SOD1-ALS patients showed trends toward improvements
www.medpagetoday.com
December 24, 2025 at 6:52 AM
Long-Term Tofersen Use May Slow ALS Progression, 3-Year Data Suggest www.medpagetoday.com/neurology/ge...
"For people with the SOD1 genetic form of ALS, these results are incredibly hopeful, documenting a substantial effect on slowing this particular form of ALS," Miller told MedPage Today.
"For people with the SOD1 genetic form of ALS, these results are incredibly hopeful, documenting a substantial effect on slowing this particular form of ALS," Miller told MedPage Today.
Reposted by L Brielmaier
At Bridging Voice, we believe communication is a human right—not a luxury. We provide free, remote, personalized support so people living with ALS can stay connected and heard.
Thank you to everyone who made this impact possible in 2025 💙
Help us close out the year strong: tinyurl.com/bv-2025
Thank you to everyone who made this impact possible in 2025 💙
Help us close out the year strong: tinyurl.com/bv-2025
December 24, 2025 at 1:37 AM
At Bridging Voice, we believe communication is a human right—not a luxury. We provide free, remote, personalized support so people living with ALS can stay connected and heard.
Thank you to everyone who made this impact possible in 2025 💙
Help us close out the year strong: tinyurl.com/bv-2025
Thank you to everyone who made this impact possible in 2025 💙
Help us close out the year strong: tinyurl.com/bv-2025
Do Parents Have Favorite Children? Of Course They Do.
And research shows the less favored children suffer for it.
www.nytimes.com/2025/12/23/w...
And research shows the less favored children suffer for it.
www.nytimes.com/2025/12/23/w...
Do Parents Have Favorite Children? Of Course They Do.
www.nytimes.com
December 23, 2025 at 6:16 PM
Do Parents Have Favorite Children? Of Course They Do.
And research shows the less favored children suffer for it.
www.nytimes.com/2025/12/23/w...
And research shows the less favored children suffer for it.
www.nytimes.com/2025/12/23/w...