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manno.se
Adnan Halim
@manno.se
160 followers 110 following 10 posts
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Reposted by Adnan Halim
glyco.me
Hiren Joshi @glyco.me · 1d
Come work with @galn.ac and @manno.se every day, and the @glyco.me as a whole!
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manno.se
Adnan Halim @manno.se · Aug 24
I (still) handle advanced mass spec instruments in the lab. Pack columns, optimize chromatography. Design and perform complicated experiments that span weeks, sometimes months. Yet, my wife doesn’t trust me with the washing machine 😣
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manno.se
Adnan Halim @manno.se · Aug 23
Together with @glyco.me, @bandolab.bsky.social and teams, we recently uncovered a link between pediatric brain tumors, POMT1/2 enzymes and KIAA1549 - full story in the preprint below:

www.biorxiv.org/content/10.1...
O-mannosylation and protein maturation check-points represent therapeutic opportunities in BRAF fusion protein oncogenesis
Fusions between protein-coding genes are common oncogenic drivers across cancers, typically pairing a proto-oncogene with partner that does not independently drive cancer. In all therapeutically actio...
www.biorxiv.org
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manno.se
Adnan Halim @manno.se · Jun 15
Awesome run and awesome company!
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Reposted by Adnan Halim
cashwood.proteaglyco.com
Chris Ashwood @cashwood.proteaglyco.com · Mar 28
Recently came across this during lit review. A solid mechanistic study with a big performance improvement as a result.
www.sciencedirect.com/science/arti...
Addressing NHS chemistry: Efficient quenching of excess TMT reagent and reversing TMT-over labelling in proteomic samples by methylamine
N-Hydroxysuccinimide (NHS) ester chemistry is used extensively across proteomics sample preparation. One of its increasingly prevalent applications is…
www.sciencedirect.com
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manno.se
Adnan Halim @manno.se · Mar 25
The outfit is a subtle hint: O-Man, O-GalNAc with some GlcNAc 🟢🟨🟦
merrylabnotts.bsky.social
Stem Cell Glycobiology Lab @merrylabnotts.bsky.social · Mar 24
@glyco.me looking mighty fine in the Italian Sunshine after an awesome talk. #GlycoGRC
A very dapper gentleman in yellow trousers, blue shirt, tie and woollen jacket stands, smiling in front of a beautiful Mountain View
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manno.se
Adnan Halim @manno.se · Mar 14
Impressive study from Heck lab www.nature.com/articles/s41...
In-depth plasma N-glycoproteome profiling using narrow-window data-independent acquisition on the Orbitrap Astral mass spectrometer - Nature Communications
While DIA has advanced standard proteomics, its application in glycoproteomics has remained limited. Here, the authors present an optimized narrow-window DIA method for N-glycopeptides, nGlycoDIA, ena...
www.nature.com
Reposted by Adnan Halim
chongg.bsky.social
Gene Chong @chongg.bsky.social · Jan 8
It’s #glycotime Fucosyltransferases FUT10 and FUT11 are protein O-fucosyltransferases (POFUTs) modifying proteins with elastin microfibril interface (EMI) domains. Curious to know the function(s) of O-fucosylating EMI domains

www.nature.com/articles/s41...
FUT10 and FUT11 are protein O-fucosyltransferases that modify protein EMI domains - Nature Chemical Biology
FUT10 and FUT11, originally annotated as α1,3-fucosyltransferases, are actually protein O-fucosyltransferases participating in a non-canonical ER quality control pathway for EMI domain-containing prot...
www.nature.com
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manno.se
Adnan Halim @manno.se · Dec 24
🟢🟢🟢🙌
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manno.se
Adnan Halim @manno.se · Dec 4
Looks correct, very cool!
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manno.se
Adnan Halim @manno.se · Nov 20
Check out the cool handle @manno.se that @glyco.me set up for me. Thx Hiren, we all know 🟢🟢🟢 is the coolest sugar 😁
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Reposted by Adnan Halim
anneimb.bsky.social
Anne Imberty @anneimb.bsky.social · Nov 17
Still time to register to awsome Glycobiology Gordon Research Conference 2025. We have a fantastic line of speakers and this will be top #glycotime in Tuscany !! Register at www.grc.org/glycobiology...
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manno.se
Adnan Halim @manno.se · Nov 15
Well deserved, the poster was 🔥🔥🔥
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Reposted by Adnan Halim
glyco.me
Hiren Joshi @glyco.me · Nov 12
New bit of work from CCG, with our newest cellular framework - GlycoCarrier
www.nature.com/articles/s41...
Mammalian cell-based production of glycans, glycopeptides and glycomodules - Nature Communications
Access to defined human glycans is crucial for biomedical research. Here, authors report Glycocarriers, a mammalian cell-based method for the sustainable and scalable production of O-, N-glycans, and ...
www.nature.com
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manno.se
Adnan Halim @manno.se · Nov 15
New York City?
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