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Manuel Thery

@manuelthery.bsky.social

3K followers 1K following 130 posts

cytoskeleton self-organization / shape, patterns and symmetry / minimal and artificial cells / biophysics teacher @ ESPCI ParisTech www.cytomorpholab.com

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Manuel Thery @manuelthery.bsky.social · Nov 27

Mix two motors of opposite polarity with microtubules and they will partition space !
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)

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Reposted by Manuel Thery

Matthias Krause @matthias-krause.bsky.social · 44m

Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI

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Manuel Thery @manuelthery.bsky.social · 1h

I see intraflagellar transport and dynamic steady states in living systems in this work by www.perry-cooper.com/about
Should we think of the bias in intracellular transports by "rewards"?

Manuel Thery @manuelthery.bsky.social · 1h

response to bottom clap 🤩

Manuel Thery @manuelthery.bsky.social · 1h

Each cube can emit a light and sound to tell its neighbours it has heard something.
Check www.scenocosme.com/reactive_mat... for more details on this reactive matter.

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Reposted by Manuel Thery

EMBO @embo.org · 2d

Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.

Deadline: 20 December 2025

https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪

Structure and Function of the Cytoskeleton

The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …

meetings.embo.org

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Reposted by Manuel Thery

bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 2d

MAP4-MAP7D1 partitioning on tyrosinated-detyrosinated microtubules coordinates lysosome positioning in nutrient signalling https://www.biorxiv.org/content/10.1101/2025.10.07.680844v1

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Manuel Thery @manuelthery.bsky.social · 2d

you mean at my place?

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Manuel Thery @manuelthery.bsky.social · 2d

What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social

rupress.org/jcb/article-...

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Reposted by Manuel Thery

Biophysical Paris @parisseminar.bsky.social · 3d

Yusuke Maeda, from the department of Chemical Engineering of Kyoto University for a seminar on

Tuesday the 21st of October at 12:00

in the main amphitheatre of the IPGG (6 rue Jean Calvin).

Title and abstract:

From Flow to Shape: Biophysical Principles of Confined Actomyosin

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Manuel Thery @manuelthery.bsky.social · 8d

are cadherin recruited in these self-contacts?

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Manuel Thery @manuelthery.bsky.social · 9d

very cool and intriguing work! do you if similar self-contact forms when two membrane protrusions collide accidentaly, ie not below the arc de triomphe?

Manuel Thery @manuelthery.bsky.social · 9d

i had to search for it 😂

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Manuel Thery @manuelthery.bsky.social · 9d

THE Erwin Frey, talking about self-organization in biological systems. Title of the seminar serie suggests it might be intended for physicists.

APS DSNP @aps-dsnp.bsky.social · 10d

📌 Join us for the next klogW seminar on October 21st at 12PM EST (register below) by Erwin Frey @physicsoflifelmu.bsky.social on "Emergence and Self-organization in Biological Systems".
Registration link:
apsphysics.zoom.us/meeting/regi...

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Manuel Thery @manuelthery.bsky.social · 9d

intracellular mechanics ! in Barcelona in February (when its freezing anywherelse) !

Felix Campelo @felixmendu.bsky.social · Jul 4

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio

meetings.embo.org/event/26-org...

Intracellular mechanics and organelle mechanobiology

Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…

meetings.embo.org

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Manuel Thery @manuelthery.bsky.social · 9d

associate prof position in biophysics !

Biozentrum, University of Basel @biozentrum.unibas.ch · 11d

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

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Manuel Thery @manuelthery.bsky.social · 10d

the drawing further suggests that the size of the rings filter the cargos.

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Reposted by Manuel Thery

Christophe 🔬 L @christlet.bsky.social · 10d

Beautiful drawing of ciliogenesis in airway cells from Sorokin, 1968: journals.biologists.com/jcs/article/.... Just shown on stage by @mahjoublab.bsky.social at #GEF25

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Manuel Thery @manuelthery.bsky.social · 10d

nice gang !

Manuel Thery @manuelthery.bsky.social · 10d

The program is outstanding. Don't miss this opportunity to celebrate a giant.

Benoit Ladoux @bladoux.bsky.social · 22d

We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.

mikeinmemoriam.sciencesconf.org

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Manuel Thery @manuelthery.bsky.social · 10d

Beautiful work Sara ! It reminds me our observations of nuclear deformation by microtubules driving chromatin remodeling and hematopoietic stem cell differentiation. But here you investigated the mechanism much further than we did 😅. The osmotic path you uncovered is fascinating !

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Manuel Thery @manuelthery.bsky.social · 11d

After so many years we keep
on drawing circles, lines, asters and arrows.

Reposted by Manuel Thery

Biophysical Paris @parisseminar.bsky.social · 16d

Paris Biological Physics Community Day (07/11/2025): Save the date!

Friday, November the 7th

Starting at 9h15

Laboratoire de Physique de l’École Normale Supérieure - Salle Jaurès - 29 rue d’Ulm 75005 Paris
www.phys.ens.psl.eu/parisyoung/

Paris Biological Physics Community Day 2025

www.phys.ens.psl.eu

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Manuel Thery @manuelthery.bsky.social · 18d

wooohooo! congratulations Alexis!

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Reposted by Manuel Thery

Yu-Chiun Wang @yuchiunwang.bsky.social · 25d

Tissues transition between solid & fluid states in development & disease; cytoplasm turns crowded or inert to literally 'solidify'. Any connections? Turns out nothing's known. @sameerthukral.bsky.social & @bipashadey29.bsky.social pulled this review off brilliantly with a conceptual synthesis.

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Reposted by Manuel Thery

Shweta Nandakumar @bucklingmt.bsky.social · 26d

Despite their high rigidity, microtubules (MTs) dynamically bend and buckle in cells. MT-self repair is inherent to their metastable nature, but it remains unclear whether just inherent repair mechanisms are sufficient to maintain MT integrity🧵 (1/9)
www.biorxiv.org/content/10.1...

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