Manuel Thery
@manuelthery.bsky.social
cytoskeleton self-organization / shape, patterns and symmetry / minimal and artificial cells / biophysics teacher @ ESPCI ParisTech
www.cytomorpholab.com
www.cytomorpholab.com
Pinned
Manuel Thery
@manuelthery.bsky.social
· Nov 27
Mix two motors of opposite polarity with microtubules and they will partition space !
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
Magnifique. c'est inspirant cette façon de revisiter des processus que l'on croit bien connus (dans les faits) sous un angle different (leur logique).
November 24, 2025 at 8:42 PM
Magnifique. c'est inspirant cette façon de revisiter des processus que l'on croit bien connus (dans les faits) sous un angle different (leur logique).
did he tell you about the cell farts? this guy made plenty of astonishing discoveries.
November 24, 2025 at 7:40 PM
did he tell you about the cell farts? this guy made plenty of astonishing discoveries.
Reposted by Manuel Thery
There's only one week left to apply to our Integrated MSc/PhD program - apply now! mattertolife.maxplanckschools.org/application
November 24, 2025 at 3:18 PM
There's only one week left to apply to our Integrated MSc/PhD program - apply now! mattertolife.maxplanckschools.org/application
we listened to it so many times in the lab! thank you Jimmy!
November 24, 2025 at 7:26 PM
we listened to it so many times in the lab! thank you Jimmy!
sorry about that. do they systematically inverse their position by rotating CW?
November 22, 2025 at 10:11 AM
sorry about that. do they systematically inverse their position by rotating CW?
hahaha well chosen Sally!
November 21, 2025 at 10:17 PM
hahaha well chosen Sally!
no we don't. But we would be happy if you can sugges some.
November 21, 2025 at 5:54 PM
no we don't. But we would be happy if you can sugges some.
yes it can happen. but not often
November 21, 2025 at 5:53 PM
yes it can happen. but not often
@ghinabadih.bsky.social and Laetitia Kurzawa from CytoMorphoLab concluded that "contractile forces direct the chiral swirling of cells".
November 21, 2025 at 1:15 PM
@ghinabadih.bsky.social and Laetitia Kurzawa from CytoMorphoLab concluded that "contractile forces direct the chiral swirling of cells".
What if one cell of the doublet prefer the counter-clockwise direction? The strongest imposes its bias.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
November 21, 2025 at 1:11 PM
What if one cell of the doublet prefer the counter-clockwise direction? The strongest imposes its bias.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
We found that it takes only two cells for the bias to take place.
Although now they are only 60% to chose the clockwise direction.
Although now they are only 60% to chose the clockwise direction.
November 21, 2025 at 1:09 PM
We found that it takes only two cells for the bias to take place.
Although now they are only 60% to chose the clockwise direction.
Although now they are only 60% to chose the clockwise direction.
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
November 21, 2025 at 1:07 PM
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Reposted by Manuel Thery
Ever wanted to do a genome-scale CRISPR screen for a microscopy phenotype? Pooled CRISPR screens are amazing, but hard to combine with imaging... Excited to share our latest work in Dev Cell on a technology platform for imaging screens and applications to primary cilia: www.cell.com/developmenta...
A microscopy-based CRISPR screening platform enables organellar functional genomics and illuminates ciliary biology
Sun et al. develop a microscopy-based CRISPR screening platform that combines ease
of implementation with flexible analysis of live-cell or antibody-based markers. Screens
in human cells using a serie...
www.cell.com
November 20, 2025 at 5:06 PM
Ever wanted to do a genome-scale CRISPR screen for a microscopy phenotype? Pooled CRISPR screens are amazing, but hard to combine with imaging... Excited to share our latest work in Dev Cell on a technology platform for imaging screens and applications to primary cilia: www.cell.com/developmenta...
Reposted by Manuel Thery
Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps.
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
Active nematic pumps | PNAS
Microfluidics involves the manipulation of flows at the microscale, typically requiring
external power sources to generate pressure gradients. Alte...
www.pnas.org
November 12, 2025 at 7:20 PM
Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps.
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
hmmm that's ennoying. and this will likely happen soon to all of us. i guess they used an AI to detect it. So you can oppose the reliability of their AI by suggesting them to write themselves a piece and submit it to their AI.
November 12, 2025 at 4:16 PM
hmmm that's ennoying. and this will likely happen soon to all of us. i guess they used an AI to detect it. So you can oppose the reliability of their AI by suggesting them to write themselves a piece and submit it to their AI.
nine fold symmetry
those-who-know know what i mean
those-who-know know what i mean
November 1, 2025 at 12:53 PM
nine fold symmetry
those-who-know know what i mean
those-who-know know what i mean
thank you Stephen!
October 31, 2025 at 11:40 AM
thank you Stephen!
Reposted by Manuel Thery
Get out your calendars! The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.
October 30, 2025 at 2:18 PM
Get out your calendars! The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.
Reposted by Manuel Thery
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
October 26, 2025 at 2:01 AM
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Tomorrow at @ISTAresearch.bsky.social in Vienna at 4:30 PM I will show and discuss how shapes can emerge (and disappear) from mixture of microtubules and molecular motors.
#morphogenesis
#morphogenesis
October 15, 2025 at 10:24 AM
Tomorrow at @ISTAresearch.bsky.social in Vienna at 4:30 PM I will show and discuss how shapes can emerge (and disappear) from mixture of microtubules and molecular motors.
#morphogenesis
#morphogenesis
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
October 14, 2025 at 1:50 PM
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
Reposted by Manuel Thery
Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI
bit.ly/Dynamic-Cell-VI
October 10, 2025 at 2:24 PM
Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI
bit.ly/Dynamic-Cell-VI
I see intraflagellar transport and dynamic steady states in living systems in this work by www.perry-cooper.com/about
Should we think of the bias in intracellular transports by "rewards"?
Should we think of the bias in intracellular transports by "rewards"?
October 10, 2025 at 2:02 PM
I see intraflagellar transport and dynamic steady states in living systems in this work by www.perry-cooper.com/about
Should we think of the bias in intracellular transports by "rewards"?
Should we think of the bias in intracellular transports by "rewards"?