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Manuel Thery

@manuelthery.bsky.social

3K followers 1K following 120 posts

cytoskeleton self-organization / shape, patterns and symmetry / minimal and artificial cells / biophysics teacher @ ESPCI ParisTech www.cytomorpholab.com

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Manuel Thery @manuelthery.bsky.social · Nov 27

Mix two motors of opposite polarity with microtubules and they will partition space !
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)

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Reposted by Manuel Thery

EMBO @embo.org · 1d

Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.

Deadline: 20 December 2025

https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪

Structure and Function of the Cytoskeleton

The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …

meetings.embo.org

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Reposted by Manuel Thery

bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 17h

MAP4-MAP7D1 partitioning on tyrosinated-detyrosinated microtubules coordinates lysosome positioning in nutrient signalling https://www.biorxiv.org/content/10.1101/2025.10.07.680844v1

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Manuel Thery @manuelthery.bsky.social · 21h

you mean at my place?

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Manuel Thery @manuelthery.bsky.social · 1d

What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social

rupress.org/jcb/article-...

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Reposted by Manuel Thery

Biophysical Paris @parisseminar.bsky.social · 2d

Yusuke Maeda, from the department of Chemical Engineering of Kyoto University for a seminar on

Tuesday the 21st of October at 12:00

in the main amphitheatre of the IPGG (6 rue Jean Calvin).

Title and abstract:

From Flow to Shape: Biophysical Principles of Confined Actomyosin

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Manuel Thery @manuelthery.bsky.social · 7d

are cadherin recruited in these self-contacts?

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Manuel Thery @manuelthery.bsky.social · 8d

very cool and intriguing work! do you if similar self-contact forms when two membrane protrusions collide accidentaly, ie not below the arc de triomphe?

Manuel Thery @manuelthery.bsky.social · 8d

i had to search for it 😂

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Manuel Thery @manuelthery.bsky.social · 8d

THE Erwin Frey, talking about self-organization in biological systems. Title of the seminar serie suggests it might be intended for physicists.

APS DSNP @aps-dsnp.bsky.social · 8d

📌 Join us for the next klogW seminar on October 21st at 12PM EST (register below) by Erwin Frey @physicsoflifelmu.bsky.social on "Emergence and Self-organization in Biological Systems".
Registration link:
apsphysics.zoom.us/meeting/regi...

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Manuel Thery @manuelthery.bsky.social · 8d

intracellular mechanics ! in Barcelona in February (when its freezing anywherelse) !

Felix Campelo @felixmendu.bsky.social · Jul 4

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio

meetings.embo.org/event/26-org...

Intracellular mechanics and organelle mechanobiology

Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…

meetings.embo.org

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Manuel Thery @manuelthery.bsky.social · 8d

associate prof position in biophysics !

Biozentrum, University of Basel @biozentrum.unibas.ch · 9d

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

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Manuel Thery @manuelthery.bsky.social · 8d

the drawing further suggests that the size of the rings filter the cargos.

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Reposted by Manuel Thery

Christophe 🔬 L @christlet.bsky.social · 8d

Beautiful drawing of ciliogenesis in airway cells from Sorokin, 1968: journals.biologists.com/jcs/article/.... Just shown on stage by @mahjoublab.bsky.social at #GEF25

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Manuel Thery @manuelthery.bsky.social · 8d

nice gang !

Manuel Thery @manuelthery.bsky.social · 9d

The program is outstanding. Don't miss this opportunity to celebrate a giant.

Benoit Ladoux @bladoux.bsky.social · 20d

We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.

mikeinmemoriam.sciencesconf.org

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Manuel Thery @manuelthery.bsky.social · 9d

Beautiful work Sara ! It reminds me our observations of nuclear deformation by microtubules driving chromatin remodeling and hematopoietic stem cell differentiation. But here you investigated the mechanism much further than we did 😅. The osmotic path you uncovered is fascinating !

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Manuel Thery @manuelthery.bsky.social · 9d

After so many years we keep
on drawing circles, lines, asters and arrows.

Reposted by Manuel Thery

Biophysical Paris @parisseminar.bsky.social · 14d

Paris Biological Physics Community Day (07/11/2025): Save the date!

Friday, November the 7th

Starting at 9h15

Laboratoire de Physique de l’École Normale Supérieure - Salle Jaurès - 29 rue d’Ulm 75005 Paris
www.phys.ens.psl.eu/parisyoung/

Paris Biological Physics Community Day 2025

www.phys.ens.psl.eu

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Manuel Thery @manuelthery.bsky.social · 16d

wooohooo! congratulations Alexis!

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Reposted by Manuel Thery

Yu-Chiun Wang @yuchiunwang.bsky.social · 23d

Tissues transition between solid & fluid states in development & disease; cytoplasm turns crowded or inert to literally 'solidify'. Any connections? Turns out nothing's known. @sameerthukral.bsky.social & @bipashadey29.bsky.social pulled this review off brilliantly with a conceptual synthesis.

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Reposted by Manuel Thery

Shweta Nandakumar @bucklingmt.bsky.social · 24d

Despite their high rigidity, microtubules (MTs) dynamically bend and buckle in cells. MT-self repair is inherent to their metastable nature, but it remains unclear whether just inherent repair mechanisms are sufficient to maintain MT integrity🧵 (1/9)
www.biorxiv.org/content/10.1...

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Reposted by Manuel Thery

BioCytoLab @schaedellab.bsky.social · 27d

Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳

We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.

Congratulations @subhambiswas.bsky.social!

www.nature.com/articles/s41...

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Reposted by Manuel Thery

Max-Planck-Gesellschaft @maxplanck.de · 29d

Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer

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Manuel Thery @manuelthery.bsky.social · 29d

Fabulous work showing how Tau catalyses microtubule repair

Subham Biswas @subhambiswas.bsky.social · 29d

Excited to share that my paper on Tau–Microtubule interactions is now published in Nature Physics!🎉

Our work shows that tau goes beyond stabilizing microtubules—it also promotes the removal of defects in the microtubule lattice.

www.nature.com/articles/s41...

Tau accelerates tubulin exchange in the microtubule lattice - Nature Physics

Beyond its known role in stabilizing microtubules, it is now shown that tau protein actively promotes lattice defect repair by enhancing tubulin turnover at topological defects.

www.nature.com

Manuel Thery @manuelthery.bsky.social · 29d

Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !

Paris Cytoskeleton Day 2025 - Sciencesconf.org

pcd2025.sciencesconf.org

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