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Reposted by Marina Parry

Clare Griffiths @statsgeekclare.bsky.social · 16d

New CMO report out today on health trends and variation in England. My team delivered this using a RAP developed in R, which made a nice change from lots of people running around putting numbers into excel then pasting into powerpoint... Was not without challenges though! www.gov.uk/government/p...

Health trends and variation in England 2025: a Chief Medical Officer report

An overview of the health of England’s population, including trends over time and geographical variation.

www.gov.uk

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Healthcare Quality Improvement Partnership (HQIP) @hqip.bsky.social · 17d

1/2 With #WorldCancerResearchDay shining a light on cancer care, we update on the HQIP-commissioned National Cancer Audit Collaborating Centre, which hosts all ten #NHS national cancer audits that are part of the National Clinical Audit and Patient Outcomes Programme.
@natcan-news.bsky.social

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National Cancer Audit Collaborating Centre (NATCAN) @natcan-news.bsky.social · 25d

Our new website is live! 🎉

All 10 national cancer audits are now in one place: bowel, OG, NHL, lung, ovarian, kidney, prostate, pancreatic, primary breast & metastatic breast.

Plus refreshed QI & new sections have been added, check it out here 👉 natcan.org.uk

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Marina Parry @marinaparry.bsky.social · Sep 9

ICYMI and want to know more about how tumor transcription-wide expression classifiers predict treatment sensitivity in advanced prostate cancers > look no further: www.cell.com/cell/pdf/S00...

Marina Parry @marinaparry.bsky.social · Sep 3

Thank you Nima!

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Prostate Cancer UK Professionals @prostateukprofs.bsky.social · Sep 2

Could transcriptome signatures identify men with advanced #ProstateCancer most likely to benefit from chemotherapy?

A brilliant team led by Prof Gerhardt Attard @ucl.ac.uk share exciting new findings in @cp-cell.bsky.social.

Grab a ☕ and read: doi.org/10.1016/j.ce...

Scientific Paper Published in Cell, titled: Tumor transcriptome-wide expression classifiers predict treatment sensitivity in advanced prostate cancers. Written by Grist et al.

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UCL News @uclnews.bsky.social · Aug 28

A new test can identify which prostate cancer patients are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, shows a new study led by Prof Gert Attard & Dr Emily Grist @uclmedsci.bsky.social
www.ucl.ac.uk/news/2025/au...

Molecular test personalises prostate cancer treatment

Testing the molecular profile of tumours identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit f...

www.ucl.ac.uk

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Marina Parry @marinaparry.bsky.social · Aug 27

REALLY thrilled to share findings from my postdoc work in the Attard lab, which form part of this www.sciencedirect.com/science/arti....

Thanks to Emily and Gert for seeing it over the line, all the funders, the Veracyte, MRC CTU & STAMPEDE teams, and patients who contributed samples. Pls share!

Tumor transcriptome-wide expression classifiers predict treatment sensitivity in advanced prostate cancers

Advanced prostate cancers respond to hormone therapy but outcomes vary and no predictive tests exist for informed treatment selection. To identify nov…

www.sciencedirect.com

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National Prostate Cancer Audit @npca-natcan.bsky.social · Apr 28

📢 Start your week with the latest National Prostate Cancer Audit study.

We found that the annual rate of metastatic prostate cancer at diagnosis was more than 60% higher in some regions than in others in England.

Paper link here 👉 bmjoncology.bmj.com/content/4/1/...

Geographic, socioeconomic and demographic inequalities in the incidence of metastatic prostate cancer at time of diagnosis in England: a population-based evaluation

Objective To evaluate the area-based incidence of metastatic prostate cancer at diagnosis, reflecting the risk of late-stage diagnosis, and overall prostate cancer incidence, reflecting the risk of ov...

bmjoncology.bmj.com

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Martin Smith @martinrsmith.bsky.social · Apr 7

NEW - Wellcome and UK Government partnering on a new health data research service, contributing up £600m together.

This will simplify secure access to health data and speed up research to better understand ill health.

wellcome.org/news/nationa...

National data service will simplify access to health data for research | Wellcome

Wellcome is partnering with the UK Government to establish a £600 million health data research service. It will simplify secure access to health data for research.

wellcome.org

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Cancer Research UK Manchester Institute @cruk-mi.bsky.social · Apr 2

Excellent video about CAcTUS trial combining many aspects of #CancerResearch in #Manchester - including #immunotherapy, #melanoma research & #LiquidBiopsies - #ctDNA

Great to hear @beckilee.bsky.social - formerly of this parish - speak about her work, plus a moving account from patient Kathy Heaton

Manchester Cancer Research Centre @mcrcnews.bsky.social · Apr 2

🧬 Melanoma is the 5th most common cancer in the UK, but Manchester researchers are transforming treatment.

The CAcTUS clinical trial uses ctDNA to find the best time to switch between targeted therapy & immunotherapy for advanced melanoma.

🎥 Learn more: www.youtube.com/watch?v=6l6V...

Melanoma research in Manchester - the CAcTUS clinical trial

YouTube video by Manchester Cancer Research Centre

www.youtube.com

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Marina Parry @marinaparry.bsky.social · Apr 1

What are the unique features, outputs and the future of NATCAN (National Cancer Audit Collaborating Centre, @natcan-news.bsky.social), where I manage the prostate @npca-natcan.bsky.social and kidney cancer audits @nkca-natcan.bsky.social?

The answers are here www.sciencedirect.com/science/arti...

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Marina Parry @marinaparry.bsky.social · Mar 12

Congratulations Anna, fantastic news!

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openRxiv @openrxiv.bsky.social · Mar 11

openRxiv has arrived!

We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences.
openrxiv.org/introducing-...

#openRxiv #OpenScience #Preprints #bioRxiv #medRxiv

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Marina Parry @marinaparry.bsky.social · Mar 11

⚠️Do you or someone you know want to come and work with me and the fantastic @npca-natcan.bsky.social @natcan-news.bsky.social teams based @collegeofsurgeons.bsky.social? Our oncological clinical lead is the super @alison-tree.bsky.social 😁.

Interested? Apply here www.jobs.ac.uk/job/DMB374/c...

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Marina Parry @marinaparry.bsky.social · Mar 10

Hello, I appreciate you can't cover absolutely everything, but where do reusable nappies sit in the equation? I'm a huge admirer of the Institute of Making and your projects.

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Lesley Goodburn @lgoodbu.bsky.social · Mar 8

If you work in a hospital or a cancer alliance take some time to look at the data from the National Cancer Audit Collaborating Centre (NATCAN) Pancreatic Cancer Audit www.natcan.org.uk/reports/npac... It will help you to find the areas that you can identify for improvement #sethslegacy

NPaCA Quarterly Data Dashboard - National Cancer Audit Collaborating Centre

The purpose of the National Pancreatic Cancer Audit (NPaCA) is to evaluate the patterns of care and outcomes for patients with pancreatic cancer in England and Wales, and to support services to improv...

www.natcan.org.uk

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Marina Parry @marinaparry.bsky.social · Mar 7

Latest from Jo, Clinical Fellow in the NPCA.

Are mHSPC patients in England receiving treatment intensification? And are all sMDTs treating patients similarly?

National Prostate Cancer Audit @npca-natcan.bsky.social · Mar 7

📢 End your week with our hot off the press paper:

"Are Evidence-Based Guidelines Translating into Clinical Practice? A National Population-Based Study of the Use of Treatment Intensification in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) in England"

www.ejcancer.com/article/S095...

https://www.ejcancer.com/article/S0959-8049(25)00116-9/fulltext•

Marina Parry @marinaparry.bsky.social · Mar 4

Nick, the link has an error.

Marina Parry @marinaparry.bsky.social · Feb 28

Sorry Madeleine, a like doesn't do justice to what you're describing and living. I wish there was more I could do.

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Southampton Clinical Trials Unit @southamptonctu.bsky.social · Feb 19

We are finalists!! 🙌

Our #data team has been shortlisted for the #ACDM25 awards for designing an open-source database to integrate clinical and translational data in #ClinicalTrials.

Read the paper here - journals.sagepub.com/doi/10.1177/...

@cancerresearchuk.org @unisouthampton.bsky.social

ACDM awards 2025, sponsored by CERTARA. Innovation in the Management of Clinical Data, Award Finalist. A picture of Charlotte Stuart, Head of Data Management and Information Systems at SCTU, and a picture of Umar Niazi, Senior Bioinformatician at SCTU.

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Bobby Bentham @rbentham.bsky.social · Feb 18

🚀 Our paper introducing ImmuneLENS, a new tool that measures T and B cell fractions from WGS data. This builds on our previous method, T cell ExTRECT, that used a signal from V(D)J recombination to measure T cells.

Out today in @naturegenet.bsky.social :
doi.org/10.1038/s41588-025-02086-5
🧵👇

ImmuneLENS characterizes systemic immune dysregulation in aging and cancer - Nature Genetics

Immune lymphocyte estimation from nucleotide sequencing (ImmuneLENS) infers B cell and T cell fractions from whole-genome sequencing data. Applied to the 100,000 Genomes Project datasets, circulating ...

www.nature.com

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Reposted by Marina Parry

Frances Ryan @francesryan.bsky.social · Jan 28

For the last 5 months, I’ve spoken to Rosy as she’s fought for care. MND means she needs a ventilator and feeding tube and yet she has been denied 24/7 carers. Rosy is now losing her voice but wants to speak out. We should all listen.

In today’s @theguardian.com www.theguardian.com/commentisfre...

A reader with a terminal illness emailed in despair. What she told me should shock us all | Frances Ryan

Rosy is unable to move, breathe or eat unassisted. Yet for hours a day she is being left completely alone, says Guardian columnist Frances Ryan

www.theguardian.com

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Marina Parry @marinaparry.bsky.social · Jan 9

Very proud to share the results of the NPCA team's hard work over the last few months.

It's a data rich report: increase in diagnoses and numbers of treatment, differences in diagnoses and treatments by age, ethnicity and deprivation.

Please share!

National Prostate Cancer Audit @npca-natcan.bsky.social · Jan 9

The National Prostate Cancer Audit State of the Nation Report 2024 has been published! It is available here www.npca.org.uk/reports/npca... alongside its appendix, methodology supplement and data tables.

NPCA State of the Nation Report 2024 - National Prostate Cancer Audit

The aim of the National Prostate Cancer Audit (NPCA) is to evaluate the patterns of care and outcomes for patients with prostate cancer in England and Wales, and to support services to improve the qua...

www.npca.org.uk

Reposted by Marina Parry

Frances Ryan @francesryan.bsky.social · Dec 31

Throughout 2024, the Guardian aimed to report on every woman allegedly killed by a man. Here are the 80 women whose deaths have led to a man being charged. Let us say their names. www.theguardian.com/uk-news/ng-i...

Killed women count: 80 women allegedly killed by men in UK in 2024

Throughout the year the Guardian aimed to report on every woman whose death has led to a man being charged

www.theguardian.com

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