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Reposted by Mark Gresnigt

Amelia Barber @ameliabarberphd.bsky.social · Jul 29

My group at is hiring a PhD student to explore how fungal pathogens that live in the environment will adapt their genomes, acquire new phenotypes, and perhaps even increased infectivity as a result of climate change. Please share!

More info and applications at @ jobs.uni-jena.de/vrbup

AI-generated drawing of a woman looking through a microscope with DNA and fungi drawn in the background. The text contains the same content as the bsky post.

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Reposted by Mark Gresnigt

Leibniz-HKI @leibniz-hki.de · Jul 22

💡 New infection strategy in #Candida albicans discovered: human #albumin reprograms its metabolism, turning harmless strains pathogenic – without the need of hyphae or toxins. #LeibnizHKI
🗞️ lmy.de/mthFi
🧪 rdcu.be/exl7d

@markgresnigt.bsky.social @aps-hki.bsky.social
@dfg.de @microverse.bsky.social

A comparison of two photos of Candida albicans shows that a denser biofilm is formed in the presence of human albumin (right) than in its absence (left). In the photos, the yeast cells were colored in a golden hue.

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Adaptive Pathogenicity Strategies @aps-hki.bsky.social · Jul 14

We are exited to share our story just out in @natcomms.nature.com on how the yeast Candida albicans can exploit human albumin to engage an alternative pathogenicity pathway, not relying on previously uncovered virulence factors.
www.nature.com/articles/s41...

Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway - Nature Communications

Candida albicans normally relies on specific pathogenicity mechanisms to cause tissue damage. This study reveals that when sensing host albumin, C. albicans, even avirulent strains, can trigger an alt...

www.nature.com

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Reposted by Mark Gresnigt

Microbial Pathogenicity Mechanisms @mpm-hki.bsky.social · May 12

Our newest review is published in @femsjournals.bsky.social! Marisa Valentine discusses the host-pathogen-microbiome interactions during #vaginal #Candida infections.🍄🧫🦠
Big thank you to Duncan Wilson and @markgresnigt.bsky.social for contributing!

👉 academic.oup.com/femsre/advan...

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trr124-funginet.bsky.social @trr124-funginet.bsky.social · Mar 31

What an incredible joint meeting „FungiNet – Pathogenic fungiand their human host“ & „Invasive Mycoses in Haematological Malignancies – IMIHM XV in Würzburg!
🌟 The discussions were enlightening, and the talks were truly inspiring.
🙌 A big thank you to everyone involved!

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Reposted by Mark Gresnigt

Slavica Janevska @slavi-jan.bsky.social · Apr 1

The meeting ended with an exciting panel discussion on possible future directions after 12 glorious years of the @dfg.de funded @trr124-funginet.bsky.social consortium. With @estukenbrock.bsky.social, Oliver Kurzai, Axel Brakhage and others.

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Ilan Schwartz @germhuntermd.bsky.social · Apr 1

Cracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical Books

Isabela Rost / Alessandro Pasqualotto and colleagues

academic.oup.com/ofid/article...

Cracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical Books

Abstract. Textbooks remain a primary source of reference and education for many health care professionals and students. This study assessed the mycology co

academic.oup.com

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Scheu Lab @scheu-immuno-lab.bsky.social · Mar 25

Fascinating evening🌇keynote given by David @sancholab.bsky.social on how the gut microbiome trains the immune system inside the bone marrow🦴 and how its metabolites impact atherosclerosis 👏🏻

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Scheu Lab @scheu-immuno-lab.bsky.social · Mar 25

And keynote speaker of day 2 Karsten Hiller of @tubraunschweig.bsky.social is giving us a deep dive into immuno metabolism in macrophages: #itaconate rules ✌🏻🤓 #Rothenfels2025

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Adaptive Pathogenicity Strategies @aps-hki.bsky.social · Mar 26

We are incredibly proud of Kar On Cheng for winning the best presentation award at the 28th Symposium: "Infection and Immune Defense". She presented her doctorate project on IL-36 and its role in inflammation during RVVC. Congratulations Kar On!!!

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Mark Gresnigt @markgresnigt.bsky.social · Mar 19

My group @aps-hki.bsky.social is looking for a new postdoc in immunology of fungal infections focusing on vulvovaginal candidiasis. Please contact me for further details in case of interest.

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Marc Swidergall @swidergall-lab.bsky.social · Jan 22

#GRCIFI 2025

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FEMS Journals @femsjournals.bsky.social · Jan 16

Pathogenic microorganisms employ adaptive strategies to escape host defense. Hitzler et al. explore how bacterial and fungal pathogens escape the host immune system. https://buff.ly/4ajQ9On
#FEMSMicrobiolRev
@markgresnigt.bsky.social

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Mark Gresnigt @markgresnigt.bsky.social · Jan 23

Proud to share our latest article with the group of Mihai Netea showing that lactic acid in the vaginal milieu modulates the Candida-host interactions that underlie the immune responses associated with vulvovaginal candidiasis www.tandfonline.com/doi/full/10....

Lactic acid in the vaginal milieu modulates the Candida-host interaction

Vulvovaginal candidiasis (VVC) is one of the most common infections caused by Candida albicans. VVC is characterized by an inadequate hyperinflammatory response and clinical symptoms associated wit...

www.tandfonline.com

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Slavica Janevska @slavi-jan.bsky.social · Jan 6

Join our team at the Leibniz-HKI as Technical Assistant - application deadline closing soon! 📣

Slavica Janevska @slavi-jan.bsky.social · Dec 10

Job alert! We have an open technician position in our lab at the Leibniz-HKI, please spread the word!
jobs.hki-jena.de/jobs/Technis...

Stellenangebot Technische*r Assistent*in (m/w/div) oder Biologielaborant*in bei Leibniz HKI Jobportal

Wissenschaft/Forschung in Jena

jobs.hki-jena.de

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Adaptive Pathogenicity Strategies @aps-hki.bsky.social · Jan 2

We are excited to share that in the last few days of 2024 our review on how bacterial and fungal pathogens🦠🍄🧫 bind and/or sense immune mediators to evade and escape the immune system has been published in @femsjournals.bsky.social #FEMSMicrobiologyReviews.
academic.oup.com/femsre/advan...

Microbial adaptive pathogenicity strategies to the host inflammatory environment

Abstract. Pathogenic microorganisms can infect a variety of niches in the human body. During infection, microbes can only persist if they adapt adequately

academic.oup.com

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Simone Andrea Biagini 🏳️‍🌈 @sabiagini.bsky.social · Nov 24

In the past years, I've found using comic-inspired color palettes super helpful when creating figures for my papers. Just came across this one and I’m definitely using it next!

💡Any comic recommendations with cool color palettes?🌈
#AcademicSky @academic-chatter.bsky.social @thephdplace.bsky.social

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Mark Gresnigt @markgresnigt.bsky.social · Nov 22

Shocking moment today: Got told by the pediatrician today that I should open a bottle of prosecco to celebrate that our son was now through his full first set of vaccinations. Apparently is not that common anymore that people let their children be fully vaccinated 🤯

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Reposted by Mark Gresnigt

Adaptive Pathogenicity Strategies @aps-hki.bsky.social · Nov 14

In our @dfgpublic.bsky.social funded research grouop we use this system in our lab to see how Candida albicans adapts to the different host stimuli we expose it to.

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Adaptive Pathogenicity Strategies @aps-hki.bsky.social · Nov 14

For our first post, we would like to share that we are enjoying how our live-cell imaging system (Funded by the state of Thuringia and co-funded by the EU) can use a neuron tool to quantify fungal hyphal growth.

See the paper by Wurster et al. who established this journals.asm.org/doi/epub/10....

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Mark Gresnigt @markgresnigt.bsky.social · Nov 19

This week my group started to work in our new labspace at the Leibniz-HKI after a lot of restructuring and reorganization. Happy we can finally get some experiments done in the new rooms.

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Mark Gresnigt @markgresnigt.bsky.social · Oct 11

My Strava would have really poor times…. 😅 I write slow

Mark Gresnigt @markgresnigt.bsky.social · Oct 10

Hello 👋🏼 all. Happy to join here for the science chats

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