markmcan.bsky.social
@markmcan.bsky.social
The Charity Engine guy. Over 1.5 billion CPU-hours donated to science and medicine so far www.charityengine.com/grants
Pinned
The Power of Charity for Protein Design - Institute for Protein Design
August 15, 2014 In this post we explore the power of charity to supply the massive computing capacity needed to support our protein design research. As shown in Figure 1, thanks to hundreds of thousan...
www.ipd.uw.edu
Ten years ago, Charity Engine began donating computing time - over 200 million hours so far - to the Institute for Protein Design's brilliant Rosetta @ Home project.
Its founder, David Baker, won the 2024 Nobel Prize for Chemistry.
Beyond proud to be a supporter! www.ipd.uw.edu/news-pages/t...
Its founder, David Baker, won the 2024 Nobel Prize for Chemistry.
Beyond proud to be a supporter! www.ipd.uw.edu/news-pages/t...
Check out this utter batshit from Stephen Miller, aka the real POTUS.
Trump's USA is no longer our friend and ally, it is simply Putin's puppet. A new Axis of Evil.
UK needs to end the special relationship right now
Trump's USA is no longer our friend and ally, it is simply Putin's puppet. A new Axis of Evil.
UK needs to end the special relationship right now
New tariff just dropped.
Americans set to pay an additional 10% tax on all goods from Germany, the UK, France, the Netherlands, Sweden, Norway, Denmark, and Finland.
It starts in two weeks, rising to 25% by June.
(Aside: A trade war with one EU country is a trade war with the entire EU).
Americans set to pay an additional 10% tax on all goods from Germany, the UK, France, the Netherlands, Sweden, Norway, Denmark, and Finland.
It starts in two weeks, rising to 25% by June.
(Aside: A trade war with one EU country is a trade war with the entire EU).
January 17, 2026 at 6:28 PM
Check out this utter batshit from Stephen Miller, aka the real POTUS.
Trump's USA is no longer our friend and ally, it is simply Putin's puppet. A new Axis of Evil.
UK needs to end the special relationship right now
Trump's USA is no longer our friend and ally, it is simply Putin's puppet. A new Axis of Evil.
UK needs to end the special relationship right now
Reposted by markmcan.bsky.social
I wonder what Londoners know that the rest of the country don’t?
January 11, 2026 at 9:26 AM
I wonder what Londoners know that the rest of the country don’t?
Reposted by markmcan.bsky.social
This is a hell of a thread
This weekend I've decided to finally read Balaji Srinivasan's terrible fucking book, "The Network State."
I've put this off for as long as I possibly could. Here goes.
thenetworkstate.com/book/tns.pdf
I've put this off for as long as I possibly could. Here goes.
thenetworkstate.com/book/tns.pdf
thenetworkstate.com
January 10, 2026 at 12:33 AM
This is a hell of a thread
Reposted by markmcan.bsky.social
We've removed the paywall from this guide so everyone can access it. 👇 Stay safe.
Just days into 2026, the killing of 37-year-old Renee Nicole Good by a federal immigration officer in Minneapolis, Minnesota, has sparked protests around the US.
If you’re planning to protest, here’s how to safeguard your digital security.
If you’re planning to protest, here’s how to safeguard your digital security.
How to Protest Safely in the Age of Surveillance
Law enforcement has more tools than ever to track your movements and access your communications. Here’s how to protect your privacy if you plan to protest.
www.wired.com
January 8, 2026 at 6:35 PM
We've removed the paywall from this guide so everyone can access it. 👇 Stay safe.
Reposted by markmcan.bsky.social
Just a reminder to everyone looking at the congressional budget and seeing $24b for NASA:
No, everything is not just fine.
NASA is not just space and science, it's also people. And more than 4000 of those people, out of over 17000 at the start of 2025, are now gone.
It will take years to recover.
No, everything is not just fine.
NASA is not just space and science, it's also people. And more than 4000 of those people, out of over 17000 at the start of 2025, are now gone.
It will take years to recover.
January 7, 2026 at 8:19 AM
Just a reminder to everyone looking at the congressional budget and seeing $24b for NASA:
No, everything is not just fine.
NASA is not just space and science, it's also people. And more than 4000 of those people, out of over 17000 at the start of 2025, are now gone.
It will take years to recover.
No, everything is not just fine.
NASA is not just space and science, it's also people. And more than 4000 of those people, out of over 17000 at the start of 2025, are now gone.
It will take years to recover.
January 7, 2026 at 1:43 PM
USA is now a rogue state, allied with Putin, leading a new Axis of Evil.
It can never be trusted again.
Time to end the special relationship, close all US military bases on UK soil, and rejoin our REAL friends in the EU once and for all
It can never be trusted again.
Time to end the special relationship, close all US military bases on UK soil, and rejoin our REAL friends in the EU once and for all
January 6, 2026 at 9:45 PM
USA is now a rogue state, allied with Putin, leading a new Axis of Evil.
It can never be trusted again.
Time to end the special relationship, close all US military bases on UK soil, and rejoin our REAL friends in the EU once and for all
It can never be trusted again.
Time to end the special relationship, close all US military bases on UK soil, and rejoin our REAL friends in the EU once and for all
You folks have spray-on cheese and "chocolate" that literally tastes of puke.
Maybe sit this one out
Maybe sit this one out
British Teen Returning From Semester In U.S. Regales Friends With Tale Of Food That Tastes Good https://theonion.com/british-teen-returning-from-semester-in-u-s-regales-friends-with-tale-of-food-that-tastes-good/
January 6, 2026 at 5:23 PM
You folks have spray-on cheese and "chocolate" that literally tastes of puke.
Maybe sit this one out
Maybe sit this one out
Anyone else having issues with bitcoin.de?
Can't withdraw, no reason given, no response to multiple support requests for over two days now.
Never a good sign... #BTC
Can't withdraw, no reason given, no response to multiple support requests for over two days now.
Never a good sign... #BTC
Bitcoins kaufen, Bitcoin Kurs bei Bitcoin.de!
Bitcoin.de ist Deutschlands erster und größter Handelsplatz für die digitale Währung Bitcoin.
bitcoin.de
January 6, 2026 at 4:54 PM
Anyone else having issues with bitcoin.de?
Can't withdraw, no reason given, no response to multiple support requests for over two days now.
Never a good sign... #BTC
Can't withdraw, no reason given, no response to multiple support requests for over two days now.
Never a good sign... #BTC
Reposted by markmcan.bsky.social
Chatham House experts and researchers are available to follow on Bluesky.
Connect with our experts here and follow them for their analysis on key international events and major global trends.
⬇️
go.bsky.app/UKHXrog
Connect with our experts here and follow them for their analysis on key international events and major global trends.
⬇️
go.bsky.app/UKHXrog
January 6, 2026 at 12:41 PM
Chatham House experts and researchers are available to follow on Bluesky.
Connect with our experts here and follow them for their analysis on key international events and major global trends.
⬇️
go.bsky.app/UKHXrog
Connect with our experts here and follow them for their analysis on key international events and major global trends.
⬇️
go.bsky.app/UKHXrog
NATO should declare that a US attack on Greenland will result in NATO immediately retaliating against Russia.
Everyone knows Putin is controlling Trump #Krasnov
Everyone knows Putin is controlling Trump #Krasnov
Wes Streeting warns of ‘disintegration’ of rules-based world order after Venezuela attack
www.theguardian.com/world/2026/j...
www.theguardian.com/world/2026/j...
Wes Streeting warns of ‘disintegration’ of rules-based world order after Venezuela attack
UK health secretary declines to criticise Donald Trump directly but suggests he is disturbed by events of recent days
www.theguardian.com
January 6, 2026 at 11:31 AM
NATO should declare that a US attack on Greenland will result in NATO immediately retaliating against Russia.
Everyone knows Putin is controlling Trump #Krasnov
Everyone knows Putin is controlling Trump #Krasnov
Reposted by markmcan.bsky.social
UK Foreign Secretary Yvette Cooper:
"Let me be very clear... Greenland is part of the Kingdom of Denmark... The future of Greenland is a matter for the Greenlanders and Danes, and no one else."
"Let me be very clear... Greenland is part of the Kingdom of Denmark... The future of Greenland is a matter for the Greenlanders and Danes, and no one else."
January 5, 2026 at 6:34 PM
UK Foreign Secretary Yvette Cooper:
"Let me be very clear... Greenland is part of the Kingdom of Denmark... The future of Greenland is a matter for the Greenlanders and Danes, and no one else."
"Let me be very clear... Greenland is part of the Kingdom of Denmark... The future of Greenland is a matter for the Greenlanders and Danes, and no one else."
Had Obama not won the Nobel Peace Prize, Trump wouldn't care less about it.
The most unloved, and unlovable, excuse for a human being that has ever lived
The most unloved, and unlovable, excuse for a human being that has ever lived
WH sources say Venezuela's opposition leader committed the "ultimate sin": She accepted the Nobel Peace prize.
“If she had turned it down and said, ‘I can’t accept it because it’s Donald Trump’s,’ she’d be the president of Venezuela today,” one said.
www.washingtonpost.com/national-sec...
“If she had turned it down and said, ‘I can’t accept it because it’s Donald Trump’s,’ she’d be the president of Venezuela today,” one said.
www.washingtonpost.com/national-sec...
January 5, 2026 at 1:44 PM
Had Obama not won the Nobel Peace Prize, Trump wouldn't care less about it.
The most unloved, and unlovable, excuse for a human being that has ever lived
The most unloved, and unlovable, excuse for a human being that has ever lived
Reposted by markmcan.bsky.social
Reposted by markmcan.bsky.social
I think the AI angle of this is obscurant. It doesn’t matter that grok is “an AI” whatever you take that to mean. Suppose X hired a team of guys to photoshop the clothes off of women and children whenever anyone asks. That’s functionally identical what happening here. It’s not complicated.
A functional country would shut Grok down permanently. Like, immediately. Right now. Last week. Whatever. Just flip the switch. Obviously.
January 4, 2026 at 11:25 PM
I think the AI angle of this is obscurant. It doesn’t matter that grok is “an AI” whatever you take that to mean. Suppose X hired a team of guys to photoshop the clothes off of women and children whenever anyone asks. That’s functionally identical what happening here. It’s not complicated.
Keep talking about the main offence that Trump is desperate to bury
January 3, 2026 at 9:40 PM
Keep talking about the main offence that Trump is desperate to bury
For 50+ years I have flipped my boots before putting them on, just in case a spider is in there.
It's never actually happened, UK spiders are harmless anyway, and my loved ones think I'm bonkers.
TODAY IT HAPPENED
It's never actually happened, UK spiders are harmless anyway, and my loved ones think I'm bonkers.
TODAY IT HAPPENED
a man in a police uniform and tie is talking to a woman .
Alt: Captain Holt from Brooklyn 99 shouting VINDICATION, punching the air, and bursting into flames of righteousness
media.tenor.com
December 30, 2025 at 3:10 PM
For 50+ years I have flipped my boots before putting them on, just in case a spider is in there.
It's never actually happened, UK spiders are harmless anyway, and my loved ones think I'm bonkers.
TODAY IT HAPPENED
It's never actually happened, UK spiders are harmless anyway, and my loved ones think I'm bonkers.
TODAY IT HAPPENED
December 29, 2025 at 4:54 PM
BRB, just putting my life savings into Hobbit Covert Systems, Inc
Sauron is appearing on the scene as concerns rise about crime among the most wealthy.
Sauron, the high-end home security startup for "super premium" customers, plucks a new CEO out of Sonos | TechCrunch
Sauron is appearing on the scene as concerns rise about crime among the most wealthy.
techcrunch.com
December 29, 2025 at 4:52 PM
BRB, just putting my life savings into Hobbit Covert Systems, Inc
Reposted by markmcan.bsky.social
this reminded me of an old post I saved on laptop - when Trump would support a candidate and if they lost, he would delete the post he supported them on then claim everyone he supported won
for the life of me, I have no idea how everyone doesn't see this by now
for the life of me, I have no idea how everyone doesn't see this by now
December 29, 2025 at 4:11 AM
this reminded me of an old post I saved on laptop - when Trump would support a candidate and if they lost, he would delete the post he supported them on then claim everyone he supported won
for the life of me, I have no idea how everyone doesn't see this by now
for the life of me, I have no idea how everyone doesn't see this by now
Holy crap.
Wait until you read the lyrics of one particular song that Nigel Farage used to sing at Dulwich college.
This should be the end of him
Wait until you read the lyrics of one particular song that Nigel Farage used to sing at Dulwich college.
This should be the end of him
December 27, 2025 at 9:58 AM
Holy crap.
Wait until you read the lyrics of one particular song that Nigel Farage used to sing at Dulwich college.
This should be the end of him
Wait until you read the lyrics of one particular song that Nigel Farage used to sing at Dulwich college.
This should be the end of him
Reposted by markmcan.bsky.social
The White House has been caught.
The administration inserted a photo of Bill Clinton, Michael Jackson, and Diana Ross into the Epstein files and falsely implied it showed them with victims.
In reality, it’s a publicly available fundraiser photo featuring Jackson and Ross’s own children.
The administration inserted a photo of Bill Clinton, Michael Jackson, and Diana Ross into the Epstein files and falsely implied it showed them with victims.
In reality, it’s a publicly available fundraiser photo featuring Jackson and Ross’s own children.
December 20, 2025 at 12:33 PM
The White House has been caught.
The administration inserted a photo of Bill Clinton, Michael Jackson, and Diana Ross into the Epstein files and falsely implied it showed them with victims.
In reality, it’s a publicly available fundraiser photo featuring Jackson and Ross’s own children.
The administration inserted a photo of Bill Clinton, Michael Jackson, and Diana Ross into the Epstein files and falsely implied it showed them with victims.
In reality, it’s a publicly available fundraiser photo featuring Jackson and Ross’s own children.