Lightnews — Scholar-powered news

Reposted by Max Korbmacher

Framework for Open and Reproducible Research Training @forrt.bsky.social · 1d

New preprint from member of FORRT - How to Develop and Use Open Educational Resources 📣

In this chapter, we position Open Educational Resources (OERs) as not only cost-saving tools but as instruments of epistemic justice and inclusion.

📃 osf.io/preprints/ed...

🧵👇

OSF

osf.io

2 11 22

Max Korbmacher @maxkorbmacher.bsky.social · 1d

OPEN FOR SUBMISSIONS! NOW!

Lukas Röseler @aufdroeseler.bsky.social · 1d

ReplicationResearch.org is now open for submissions!

Submit replications and reproductions from many different fields, as well as conceptual contributions. With diamond OA, open and citable peer review reports, and reproducibility checks, we push the boundaries of open and fair publishing.

1

Max Korbmacher @maxkorbmacher.bsky.social · 3d

Prolonged White Matter Remodeling Trajectories Predict Cognitive and Emotional Recovery After Mild Traumatic Brain Injury, 03 October 2025 (preprint)

Aishwarya Rajesh, Timothy Laumann, Qing Wang et al.

doi.org/10.21203/rs....

https://doi.org/10.21203/rs.3.rs-7682138/v1]

Max Korbmacher @maxkorbmacher.bsky.social · 5d

ComBatLS: A Location- and Scale-Preserving Method for Multi-Site Image Harmonization

doi.org/10.1002/hbm....

ComBatLS: A Location‐ and Scale‐Preserving Method for Multi‐Site Image Harmonization

We introduce ComBatLS, a new harmonization method that preserves the effects of biological covariates like sex and age on brain feature distributions' variances or scale parameters. We show that ComB...

doi.org

Max Korbmacher @maxkorbmacher.bsky.social · 7d

Haukvik, U.K., Wolfers, T., Tesli, N. et al. Individual-level deviations from normative brain morphology in violence, psychosis, and psychopathy. Transl Psychiatry 15, 118 (2025). doi.org/10.1038/s413...

Individual-level deviations from normative brain morphology in violence, psychosis, and psychopathy - Translational Psychiatry

Translational Psychiatry - Individual-level deviations from normative brain morphology in violence, psychosis, and psychopathy

doi.org

Max Korbmacher @maxkorbmacher.bsky.social · 8d

Max Korbmacher @maxkorbmacher.bsky.social · 10d

Judged by your neighbors: A novel framework for personalized assessment of brain structural aging effects in diverse populations

Ramona Leenings et al doi.org/10.1101/2024...

Judged by your neighbors: A novel framework for personalized assessment of brain structural aging effects in diverse populations

Despite their promise, current neuroimaging biomarkers often fail to capture the full spectrum of inter-individual variability in brain structure and aging effects. This limits their ability to detect...

doi.org

Reposted by Max Korbmacher

Nature Reviews Neurology @natrevneurol.nature.com · 10d

Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia www.nature.com/articles/s41...

Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia - Nature Communications

Individuals with schizophrenia show reduced structural similarity in temporal, cingulate, and insular lobes, especially those with worse cognition and symptoms, affecting late maturing association areas with low metabolism and high neurotransmission.

www.nature.com

2 4

Reposted by Max Korbmacher

Imaging Neuroscience @imagingneurosci.bsky.social · 12d

New paper in Imaging Neuroscience by Peder A.G. Lillebostad, Arvid Lundervold, et al:

Deep-learning segmentation of the substantia nigra from multiparametric MRI: Application to Parkinson’s disease

doi.org/10.1162/IMAG...

1 9

Reposted by Max Korbmacher

Lukas Röseler @aufdroeseler.bsky.social · 12d

How to decide what to replicate or reproduce? We recommend priotizing studies with "high value" or unclear results, considering practical limits, watching for bias, and always communicate choices openly.

Handbook chapter: forrt.org/replication_handbook/choosing_study.html

3 Choosing the Target Study – Handbook for Reproduction and Replication Studies

How to carry out reproductions and replications in the social, cognitive, and behavioral sciences

forrt.org

3

Max Korbmacher @maxkorbmacher.bsky.social · 13d

So, perhaps the ventricular gradient tells us something general about neurological conditions.

Max Korbmacher @maxkorbmacher.bsky.social · 13d

Additionally, periventricular lesions are common in multiple sclerosis.

1

Max Korbmacher @maxkorbmacher.bsky.social · 13d

The findings that make a lot of sense considering ventricular enlargement during (both healthy and pathological) ageing, as well as ventricle-near white matter being sensitive to age.

doi.org/10.1002/hbm....

Brain‐wide associations between white matter and age highlight the role of fornix microstructure in brain ageing

Conventional and advanced diffusion MRI approaches predict brain age consistently, yet best when combined. Fornix and forceps minor were central regions for these predictions across diffusion approa.....

doi.org

1 1

Max Korbmacher @maxkorbmacher.bsky.social · 13d

Periventricular gradient of normal-appearing white matter in normal aging and multiple neurological diseases

doi.org/10.1016/j.ja...

Zhizheng Zhuo et al 2025, Journal of Advanced Research

Redirecting

doi.org

1

Max Korbmacher @maxkorbmacher.bsky.social · 13d

Does it say anywhere that contents were AI generated? What about the journal policies?
But I guess yes!

1

Reposted by Max Korbmacher

François Jabouille @francois-jabouille.bsky.social · 15d

📰 New preprint: Replicability and transparency in physical therapy research: Time to wake up 📰

Where does physical therapy stand on the replication crisis and open-science practices?

We have identified significant shortcomings in current physical therapy research practice
👉 doi.org/10.1101/2025...

2 3 5

Max Korbmacher @maxkorbmacher.bsky.social · 17d

Out today! “Measuring the semantic priming effect across many languages” Nat Hum Beh.

@erinbuchanan.bsky.social et al.

In brief: Semantic priming seems to work

doi.org/10.1038/s415...

Measuring the semantic priming effect across many languages - Nature Human Behaviour

In this Stage 2 Registered Report, Buchanan et al. show evidence confirming the phenomenon of semantic priming across speakers of 19 diverse languages.

doi.org

1

Max Korbmacher @maxkorbmacher.bsky.social · 18d

A potential starting point to implement multiverse analysis for complex data, such as neuroimaging.

"Crowdsourcing multiverse analyses to explore the impact of different data-processing and analysis decisions: A tutorial"

Tom Heyman et al 2025

pubmed.ncbi.nlm.nih.gov/40965962/

Crowdsourcing multiverse analyses to explore the impact of different data-processing and analysis decisions: A tutorial - PubMed

When processing and analyzing empirical data, researchers regularly face choices that may appear arbitrary (e.g., how to define and handle outliers). If one chooses to exclusively focus on a particula...

pubmed.ncbi.nlm.nih.gov

3

Max Korbmacher @maxkorbmacher.bsky.social · 18d

Brain age gap reduction following exercise mirrors clinical improvements in schizophrenia spectrum disorders

@denizyilmaz.bsky.social et al 2025, NeuroImage: clinical

doi.org/10.1016/j.ni...

doi.org

Max Korbmacher @maxkorbmacher.bsky.social · 18d

Got a new preprint where we phenotype the MS brain which is clinically relevant.

Normative Modelling of Brain Volume for Diagnostic and Prognostic Stratification in Multiple Sclerosis

doi.org/10.1101/2025...

Normative Modelling of Brain Volume for Diagnostic and Prognostic Stratification in Multiple Sclerosis

Background Brain atrophy is a hallmark of multiple sclerosis (MS). For clinical translatability and individual-level predictions, brain atrophy needs to be put into context of the broader population, ...

doi.org

1

Max Korbmacher @maxkorbmacher.bsky.social · 21d

Impressive results from the Norwegian mother and child study:

Associations of polygenic risk scores for major depression and depression severity: an investigation of 105 623 individuals with 16 years follow-up

doi.org/10.1038/s413...

Associations of polygenic risk scores for major depression and depression severity: an investigation of 105 623 individuals with 16 years follow-up - Molecular Psychiatry

Molecular Psychiatry - Associations of polygenic risk scores for major depression and depression severity: an investigation of 105 623 individuals with 16 years follow-up

doi.org

1

Max Korbmacher @maxkorbmacher.bsky.social · 22d

For vascular dementia, type 2 diabetes conferred the greatest risk (HR 1.33, 95% CI: 1.07 to 1.64). Hyperlipidemia was the sole cardiometabolic factor significantly associated with Alzheimer's disease (AD) risk (HR 1.21, 95% CI: 1.11 to 1.32).

Max Korbmacher @maxkorbmacher.bsky.social · 22d

During a 7-year median follow-up, type 2 diabetes was associated with the highest risk of all-cause dementia (hazard ratio [HR] 1.18, followed by hypertension and hyperlipidemia.

1

Max Korbmacher @maxkorbmacher.bsky.social · 22d

Impact of cardiometabolic conditions on the progression from mild cognitive impairment to dementia: A large cohort study

pubmed.ncbi.nlm.nih.gov/40951936/

Impact of cardiometabolic conditions on the progression from mild cognitive impairment to dementia: A large cohort study - PubMed

Type 2 diabetes, hypertension, and hyperlipidemia are associated with a high risk of developing all-cause dementia in participants already diagnosed with mild cognitive impairment (MCI). Type 2 diabet...

pubmed.ncbi.nlm.nih.gov

1 1

Max Korbmacher @maxkorbmacher.bsky.social · 22d

Nice summary of the current animal (rodent) models for MS medication development and connected challenges.

Lost in translation: rethinking animal models of progressive MS (an
industry perspective)

doi.org/10.1016/j.ms...

Redirecting

doi.org

2