mesoSPIM: Clear Images. Big samples. Open source.
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mesospim.bsky.social
mesoSPIM: Clear Images. Big samples. Open source.
@mesospim.bsky.social
Light-sheet microscopes for large samples. Open source hardware and software. Run by @nvladimus.bsky.social and @voigtvision.bsky.social

Overview: www.mesospim.org
Mailing list: http://eepurl.com/hPBRhj
Forum: forum.image.sc/tag/mesospim
Pinned
Final program of the 10-year #mesoSPIM2025 Anniversary Symposium, October 13-15 in Zurich! Amazing lineup of speakers: biologists, physicists, developers, computer scientists and industry experts! Join us to learn, present, and connect! Registration until Sept. 15. www.adabd.uzh.ch/en/events/me...
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
We're still exploring how to improve LSFM performance with "big" detection air objectives, where field curvature often limits achievable FOV. Here, Steven introduces curvedASLM, a method to dynamically correct field curvature (along one axis) in axially scanned setups www.biorxiv.org/content/10.6...
December 10, 2025 at 8:12 PM
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
Fun to see photos from the @mesospim.bsky.social Symposium this last October.
December 3, 2025 at 11:11 AM
The 10 Years of #mesoSPIM Symposium was a blast! 🔟🎂The excitement was palpable, and we were all inspired. Three days flew by fast! Thanks to all the attendees, speakers, organizing team, and our sponsors for making it such a memorable event! Let's shape the next 10y of microscopy together! 💪❤️🔬
October 16, 2025 at 3:43 PM
📅 Start: 01.12.2025 (or on mutual agreement)
⏳ Application deadline: 31.10.2025

Curious? Learn more and apply here: t.uzh.ch/1U3

3/3
UZH: Laboratory Technician or Research Assistant in Tissue Clearing, Immunostaining, and Light-Sheet Microscopy
The Microscopy Innovation Platform is a technology platform run by the University Research Priority Program (URPP) Adaptive Brain Circuits in Development and Learning (AdaBD). The Platform is also emb...
t.uzh.ch
October 10, 2025 at 8:58 AM
In this role, you will:
- Clear, stain, and image biological tissues
- Process and share imaging datasets
- Support and train platform users

We’re looking for candidates with lab experience, curiosity, and practical knowledge in tissue processing and fluorescence microscopy.

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UZH: Laboratory Technician or Research Assistant in Tissue Clearing, Immunostaining, and Light-Sheet Microscopy
The Microscopy Innovation Platform is a technology platform run by the University Research Priority Program (URPP) Adaptive Brain Circuits in Development and Learning (AdaBD). The Platform is also emb...
t.uzh.ch
October 10, 2025 at 8:58 AM
Job opportunity at the University of Zurich! 📢

We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.

1/3
October 10, 2025 at 8:58 AM
Both are experienced clinical pathologists who are master users of #mesoSPIM and developed their own way of staining and clearing the most challenging tissues in their clinical practice. Want to learn which method will work best with your samples? Join us at #mesoSPIM2025 t.uzh.ch/1Ss
3/3
Registration
t.uzh.ch
August 27, 2025 at 10:32 AM
Our invited speakers Dr. Anna Maria Reuss and Dr. Hei Ming Lai show astonishing results in this field with their new methods, #aDISCO and #INSIHGT, respectively, at the #mesoSPIM2025 symposium.
2/3
August 27, 2025 at 10:32 AM
Is it possible to stain specific proteins and cell types in old formalin-fixed human tissues and make them transparent for light-sheet imaging and clinical 3D diagnostics?

🧵 1/3
August 27, 2025 at 10:32 AM
Final program of the 10-year #mesoSPIM2025 Anniversary Symposium, October 13-15 in Zurich! Amazing lineup of speakers: biologists, physicists, developers, computer scientists and industry experts! Join us to learn, present, and connect! Registration until Sept. 15. www.adabd.uzh.ch/en/events/me...
August 22, 2025 at 3:36 PM
📣We have opened our official User Forum: forum.image.sc/tag/mesospim
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
Topics tagged mesospim
Topics tagged mesospim
forum.image.sc
August 22, 2025 at 8:04 AM
Join us in Zurich or online: t.uzh.ch/1Ss
Registration
t.uzh.ch
August 20, 2025 at 11:38 AM
How to image across scales from organs to synapses, unravel biological mechanisms and handle massive data?
Learn more from @adamkglaser.bsky.social, senior scientist at the Allen Institute and the lead developer of #ExA-SPIM technique, at the #mesoSPIM2025 Symposium, Oct 13-15.
August 20, 2025 at 11:38 AM
💥How can light-sheet help reveal dark matter?💥
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
August 18, 2025 at 9:28 AM
What a pleasure to image such samples 🥰
August 13, 2025 at 3:01 PM
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
#Deeplearning-based #CRISPR DNA integration and editing by Thomas Naert & Sören Lienkamp & Co with lots of @mesospim.bsky.social #lightsheet #Microscopy data of tadpoles (and some taken with the #Schmidt #multiimmersion objective prototype!) 🔬🐸 www.nature.com/articles/s41...
August 13, 2025 at 2:09 PM
We’re excited to welcome @kevin-dean.bsky.social to the #mesoSPIM2025 Symposium! Explore his innovations in Multiscale Cleared-Tissue Axially Swept Light-Sheet Microscopy for imaging from organ to subcellular levels.
🗺️Oct 13–15 | Zurich & hybrid
Interested? Register now: t.uzh.ch/1Ss
August 12, 2025 at 9:50 AM
Abstract Submission Deadline: TOMORROW, July 15-th 🎇
🎉 Call for Abstracts! 🎉
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
July 14, 2025 at 10:17 AM
🎉 Call for Abstracts! 🎉
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
July 3, 2025 at 10:27 AM
June 12, 2025 at 9:15 AM
Highlights:
🗣️ Keynotes & lightning talks
👩‍🔬 Maker Day for microscope builders
🤝 Meet devs, users & industry
Join us to shape the future of open-source microscopy!
#mesoSPIM2025 #openscience
June 12, 2025 at 9:15 AM
Submit your work in any of these areas:
🧠 Bio/Neuro/Phys imaging
🧼 Tissue clearing techniques
🖥️ Image analysis tools (open or commercial)
🔧 Hardware and software (open or commercial)
Talks, posters & demos welcome!
Abstract submission: ema.uzh.ch/R7YRN
June 12, 2025 at 9:15 AM
🎉 Call for Abstracts! 🎉
We’re celebrating 10 years of #mesoSPIM #opensource initiative – join us at the symposium for talks, demos & posters on open-source light-sheet microscopy, tissue clearing, and imaging!
Dates: October 13-15, 2025
Location: Zurich, Switzerland
Registration: ema.uzh.ch/R7YRN
June 12, 2025 at 9:15 AM
Happy imaging!
June 10, 2025 at 6:08 PM
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
🔬 On June 6, we inaugurated the first #MesoSPIM in France at INRAE Jouy-en-Josas & ENS Paris-Saclay! A big thanks to @nvladimus.bsky.social , @mgarbelli.bsky.social ,Angeliki Vavladeli & all speakers and sponsors. Exciting step forward for #opensource imaging & interdisciplinary science! #microscopy
June 10, 2025 at 10:34 AM