Mindaugas Galvosas, MD
@mgalvosas.bsky.social
Cough as a Digital Biomarker and First Digital Therapeutic (DTx) for chronic cough @ hyfe.com, coughpro.com | prev. founder of wandering prevention tech for dementia | interested in Digital Health | my opinions
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Who should I add? Please nominate/share, thank you!
go.bsky.app/EoPCjso
Happy Thanksgiving to those who celebrate! 🦃
November 27, 2025 at 7:36 AM
Happy Thanksgiving to those who celebrate! 🦃
Super interesting relationship - I wonder what’s the mechanism and what would continuous objective cough monitoring data show
November 27, 2025 at 7:36 AM
Super interesting relationship - I wonder what’s the mechanism and what would continuous objective cough monitoring data show
So many posts on Reddit where patients complain about their cough while being on GLPs, and many comments replying this is ‘silent reflux’… today’s JAMA publication is shedding more light on cough and its relationship to GLPs
Cough monitoring is the way to study this objectively
Cough monitoring is the way to study this objectively
November 26, 2025 at 9:58 PM
So many posts on Reddit where patients complain about their cough while being on GLPs, and many comments replying this is ‘silent reflux’… today’s JAMA publication is shedding more light on cough and its relationship to GLPs
Cough monitoring is the way to study this objectively
Cough monitoring is the way to study this objectively
Reposted by Mindaugas Galvosas, MD
Use of glucagon-like peptide-1 receptor agonists (#GLP1RA) in adults with type 2 #diabetes was associated with an increased risk of new chronic cough compared with other second-line diabetes medications.
ja.ma/3XfGfHV
ja.ma/3XfGfHV
November 26, 2025 at 4:30 PM
Use of glucagon-like peptide-1 receptor agonists (#GLP1RA) in adults with type 2 #diabetes was associated with an increased risk of new chronic cough compared with other second-line diabetes medications.
ja.ma/3XfGfHV
ja.ma/3XfGfHV
If you’re taking GLPs and thinking that your cough is getting worse - use the free wellness app CoughPro to monitor your cough objectively and have more informed conversations about that cough with your HCP!
November 26, 2025 at 9:47 PM
If you’re taking GLPs and thinking that your cough is getting worse - use the free wellness app CoughPro to monitor your cough objectively and have more informed conversations about that cough with your HCP!
This is unexpected! Continuous cough monitoring can now provide objective insights on:
- cough baseline vs developing sustained/worsened cough
- cough patterns & severity (bouts, cough-free time)
Super curious what the objective results would show!
- cough baseline vs developing sustained/worsened cough
- cough patterns & severity (bouts, cough-free time)
Super curious what the objective results would show!
GLP-1 drugs may be associated with an increased risk of chronic cough
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Glucagon-Like Peptide-1 Receptor Agonists and Chronic Cough
This cohort study examines the clinical association between glucagon-like peptide 1 receptor agonists and chronic cough.
jamanetwork.com
November 26, 2025 at 9:20 PM
This is unexpected! Continuous cough monitoring can now provide objective insights on:
- cough baseline vs developing sustained/worsened cough
- cough patterns & severity (bouts, cough-free time)
Super curious what the objective results would show!
- cough baseline vs developing sustained/worsened cough
- cough patterns & severity (bouts, cough-free time)
Super curious what the objective results would show!
Ligence from Lithuania 🇱🇹 announces that its AI-powered echocardiography software, Ligence Heart, has received FDA clearance!
ligence.io/ligence-hear...
ligence.io/ligence-hear...
Ligence Heart receives FDA 510(k) clearance - Ligence
Ligence Heart has received FDA 510(k) clearance. The clearance enables U.S. healthcare providers to generate reliable and reproducible cardiac measurements, addressing one of the most time-consuming s...
ligence.io
November 26, 2025 at 4:25 PM
Ligence from Lithuania 🇱🇹 announces that its AI-powered echocardiography software, Ligence Heart, has received FDA clearance!
ligence.io/ligence-hear...
ligence.io/ligence-hear...
This model for COPD exacerbations could allow for more individualised prognostic and therapeutic implications.
Digital longitudinal data is probably the most realistic way to operationalise B+A dimensions at scale by anchoring acuity in personalised baselines.
www.thelancet.com/journals/lan...
Digital longitudinal data is probably the most realistic way to operationalise B+A dimensions at scale by anchoring acuity in personalised baselines.
www.thelancet.com/journals/lan...
Multidimensional prognostic risk stratification of COPD exacerbations: the baseline, acuity, and trigger (BAt) model
Exacerbations punctuate the natural course of chronic obstructive pulmonary disease
(COPD), posing a substantial burden on patients and health-care systems. Understanding
the severity of an acute exac...
www.thelancet.com
November 26, 2025 at 9:50 AM
This model for COPD exacerbations could allow for more individualised prognostic and therapeutic implications.
Digital longitudinal data is probably the most realistic way to operationalise B+A dimensions at scale by anchoring acuity in personalised baselines.
www.thelancet.com/journals/lan...
Digital longitudinal data is probably the most realistic way to operationalise B+A dimensions at scale by anchoring acuity in personalised baselines.
www.thelancet.com/journals/lan...
Study links long-term black carbon exposure to increased asthma, COPD risk
Findings highlight the need for targeted air quality regulations to reduce BC emissions. There's potential for longitudinal objective respiratory (eg cough) symptom monitoring.
www.sciencedirect.com/science/arti...
Findings highlight the need for targeted air quality regulations to reduce BC emissions. There's potential for longitudinal objective respiratory (eg cough) symptom monitoring.
www.sciencedirect.com/science/arti...
Long-term exposure to black carbon and incident asthma and chronic obstructive pulmonary disease in adults: The Danish Nurse Cohort
Air pollution is a known risk factor for chronic respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). However, evi…
www.sciencedirect.com
November 26, 2025 at 9:35 AM
Study links long-term black carbon exposure to increased asthma, COPD risk
Findings highlight the need for targeted air quality regulations to reduce BC emissions. There's potential for longitudinal objective respiratory (eg cough) symptom monitoring.
www.sciencedirect.com/science/arti...
Findings highlight the need for targeted air quality regulations to reduce BC emissions. There's potential for longitudinal objective respiratory (eg cough) symptom monitoring.
www.sciencedirect.com/science/arti...
AI-generated "letters to the editor"
Dr. Carlos Chaccour, University of Navarra, noticed something fishy about a letter to the editor the New England Journal of Medicine received shortly after it published a paper of his on malaria treatment in July.
www.marketplace.org/episode/2025...
Dr. Carlos Chaccour, University of Navarra, noticed something fishy about a letter to the editor the New England Journal of Medicine received shortly after it published a paper of his on malaria treatment in July.
www.marketplace.org/episode/2025...
AI-generated "letters to the editor" are flooding academic publications
Dr. Carlos Chaccour at the University of Navarra says AI-written letters to the editor are on the rise in academic journals, raising questions about authenticity, accountability, and the future of sch...
www.marketplace.org
November 25, 2025 at 10:52 AM
AI-generated "letters to the editor"
Dr. Carlos Chaccour, University of Navarra, noticed something fishy about a letter to the editor the New England Journal of Medicine received shortly after it published a paper of his on malaria treatment in July.
www.marketplace.org/episode/2025...
Dr. Carlos Chaccour, University of Navarra, noticed something fishy about a letter to the editor the New England Journal of Medicine received shortly after it published a paper of his on malaria treatment in July.
www.marketplace.org/episode/2025...
A hypothesis that cannabidiol could alleviate refractory chronic cough by targeting TRPV1 is somewhat supported by a convergence of mechanistic and preliminary evidence...
November 24, 2025 at 9:11 PM
A hypothesis that cannabidiol could alleviate refractory chronic cough by targeting TRPV1 is somewhat supported by a convergence of mechanistic and preliminary evidence...
In precision health, clinically meaningful parameters are quantified to individualise therapies and track response.
Cough, one of the most common reasons for seeking care and a key respiratory sign, has historically been hard to measure reliably:
www.emjreviews.com/respiratory/...
Cough, one of the most common reasons for seeking care and a key respiratory sign, has historically been hard to measure reliably:
www.emjreviews.com/respiratory/...
Counting Coughs: ERS 2025 Highlights on Objective Cough Monitoring
In precision health, clinically meaningful parameters are quantified to individualise therapies and track response. Cough, one of...
www.emjreviews.com
November 24, 2025 at 8:04 PM
In precision health, clinically meaningful parameters are quantified to individualise therapies and track response.
Cough, one of the most common reasons for seeking care and a key respiratory sign, has historically been hard to measure reliably:
www.emjreviews.com/respiratory/...
Cough, one of the most common reasons for seeking care and a key respiratory sign, has historically been hard to measure reliably:
www.emjreviews.com/respiratory/...
This new Review in the @LancetDigitalH bridges the gap between rapid technological innovation in digital cough monitoring tools and their practical clinical implementation.
The authors identify 5 key clinical use cases for objective cough monitoring:
...
The authors identify 5 key clinical use cases for objective cough monitoring:
...
November 24, 2025 at 10:52 AM
This new Review in the @LancetDigitalH bridges the gap between rapid technological innovation in digital cough monitoring tools and their practical clinical implementation.
The authors identify 5 key clinical use cases for objective cough monitoring:
...
The authors identify 5 key clinical use cases for objective cough monitoring:
...
Leading health systems like Mayo Clinic invest $1B+ in AI across 200+ projects. These portfolio approaches signal that organizations are moving beyond pilots to production deployment, creating opportunities for specialized solutions that integrate into broader AI strategies.
November 23, 2025 at 1:59 PM
Leading health systems like Mayo Clinic invest $1B+ in AI across 200+ projects. These portfolio approaches signal that organizations are moving beyond pilots to production deployment, creating opportunities for specialized solutions that integrate into broader AI strategies.
Health systems using ambient scribes are equally likely to switch vendors as stay put over three years. Low switching costs and commoditization pressures suggest single-feature products face retention challenges without expanding into adjacent clinical workflows.
November 23, 2025 at 1:57 PM
Health systems using ambient scribes are equally likely to switch vendors as stay put over three years. Low switching costs and commoditization pressures suggest single-feature products face retention challenges without expanding into adjacent clinical workflows.
Healthcare AI spending hit $1.4 billion in 2025, nearly triple the prior year. This represents more capital than the entire vertical AI market captured in 2024, demonstrating unprecedented investment velocity in healthcare-specific applications.
November 23, 2025 at 1:56 PM
Healthcare AI spending hit $1.4 billion in 2025, nearly triple the prior year. This represents more capital than the entire vertical AI market captured in 2024, demonstrating unprecedented investment velocity in healthcare-specific applications.
The correlation between cough severity and asthma control is stronger in patients whose cough occurred with shortness of breath compared to isolated cough.
This suggests different cough phenotypes within asthma with varying clinical implications.
This suggests different cough phenotypes within asthma with varying clinical implications.
November 23, 2025 at 1:44 PM
The correlation between cough severity and asthma control is stronger in patients whose cough occurred with shortness of breath compared to isolated cough.
This suggests different cough phenotypes within asthma with varying clinical implications.
This suggests different cough phenotypes within asthma with varying clinical implications.
Population-based cough surveillance could enable early detection of respiratory disease outbreaks. Stationary cough monitoring sensors in public spaces complement individual monitoring for public health applications.
November 23, 2025 at 1:40 PM
Population-based cough surveillance could enable early detection of respiratory disease outbreaks. Stationary cough monitoring sensors in public spaces complement individual monitoring for public health applications.
Wearable cough monitors (eg smartwatch) enable ambulatory assessment that captures real-world disease burden. This contrasts with clinic-based evaluations that may not reflect typical patient experiences.
November 23, 2025 at 1:38 PM
Wearable cough monitors (eg smartwatch) enable ambulatory assessment that captures real-world disease burden. This contrasts with clinic-based evaluations that may not reflect typical patient experiences.
Integration of cough monitoring with existing disease management platforms would create a comprehensive digital health ecosystem. Combined with medication tracking and symptom reporting, cough data can really enrich clinical decision-making.
November 23, 2025 at 1:37 PM
Integration of cough monitoring with existing disease management platforms would create a comprehensive digital health ecosystem. Combined with medication tracking and symptom reporting, cough data can really enrich clinical decision-making.
Privacy-preserving algorithms that detect cough without recording full conversations and any audio address major adoption barriers. Selective time-stamping of cough events eliminates privacy concerns while maintaining clinical utility.
November 23, 2025 at 1:35 PM
Privacy-preserving algorithms that detect cough without recording full conversations and any audio address major adoption barriers. Selective time-stamping of cough events eliminates privacy concerns while maintaining clinical utility.
For asthma patients, nocturnal cough frequency correlates with disease control and can predict exacerbations. Cough monitoring insights can enable proactive management adjustments before symptoms escalate.
November 23, 2025 at 1:34 PM
For asthma patients, nocturnal cough frequency correlates with disease control and can predict exacerbations. Cough monitoring insights can enable proactive management adjustments before symptoms escalate.