Michael Rera
@michaelrera.bsky.social
researching on ageing & death
PI UTELife lab, fly wrangler
cofounder/gravedigger @publisciences @publifactory
https://michaelrera.github.io/
PI UTELife lab, fly wrangler
cofounder/gravedigger @publisciences @publifactory
https://michaelrera.github.io/
Pinned
Michael Rera
@michaelrera.bsky.social
· Feb 11
Proteome-wide prediction of the Functional Impact of Missense Variants with ProteoCast
Background: Dissecting the functional impact of genetic mutations is essential to advancing our understanding of genotype-phenotype relationships and identifying new therapeutic targets. Despite the p...
www.biorxiv.org
Happy to announce the latest preprint of PhD candidate Mariana Abakarova (not yet on bluesky) tinyurl.com/4ewd2v85 in co-supervision with Prof. @laineelodie.bsky.social @sorbonne-universite.fr / @upariscite
tinyurl.com/2ntnfvw3
Funded by @agencerecherche.bsky.social ADAGIO and @erc.europa.eu PROMISE
tinyurl.com/2ntnfvw3
Funded by @agencerecherche.bsky.social ADAGIO and @erc.europa.eu PROMISE
Reposted by Michael Rera
Fascinating article by @heidiledford.bsky.social: single cells from one 74 year-old man were a truly chaotic mosaic of mutation: some cells had a missing Y chromosome, chromosomes with extra arms, and more.
We are all mosaics: vast genetic diversity found between cells in a single person
Technical advances allow researchers to trace the genetic changes that occur over time.
www.nature.com
November 27, 2025 at 10:55 AM
Fascinating article by @heidiledford.bsky.social: single cells from one 74 year-old man were a truly chaotic mosaic of mutation: some cells had a missing Y chromosome, chromosomes with extra arms, and more.
Reposted by Michael Rera
Au moins, Jordan Bardella sait se situer politiquement !
Pour soutenir la lutte dessinée, engagée et indépendante :
▶️ ko-fi.com/allanbarte
▶️ fr.tipeee.com/allan-barte
▶️ Source : www.huffingtonpost.fr/politique/ar...
Pour soutenir la lutte dessinée, engagée et indépendante :
▶️ ko-fi.com/allanbarte
▶️ fr.tipeee.com/allan-barte
▶️ Source : www.huffingtonpost.fr/politique/ar...
November 27, 2025 at 10:44 AM
Au moins, Jordan Bardella sait se situer politiquement !
Pour soutenir la lutte dessinée, engagée et indépendante :
▶️ ko-fi.com/allanbarte
▶️ fr.tipeee.com/allan-barte
▶️ Source : www.huffingtonpost.fr/politique/ar...
Pour soutenir la lutte dessinée, engagée et indépendante :
▶️ ko-fi.com/allanbarte
▶️ fr.tipeee.com/allan-barte
▶️ Source : www.huffingtonpost.fr/politique/ar...
Reposted by Michael Rera
Excited to share the latest work from the lab:
rdcu.be/eRWuD
Great team effort, led by @enriberti.bsky.social first at @unil.bsky.social and now @unifr.bsky.social; with fantastic collaborators @ribeirocarlitos.bsky.social and @dahaniel.muench.bio.
rdcu.be/eRWuD
Great team effort, led by @enriberti.bsky.social first at @unil.bsky.social and now @unifr.bsky.social; with fantastic collaborators @ribeirocarlitos.bsky.social and @dahaniel.muench.bio.
Evolution of taste processing shifts dietary preference
Nature - Calcium imaging of taste neurons and the ventral brain provides insight into evolutionary divergence of food choice in Drosophila species, supporting a role of sensorimotor processing in...
rdcu.be
November 27, 2025 at 8:36 AM
Excited to share the latest work from the lab:
rdcu.be/eRWuD
Great team effort, led by @enriberti.bsky.social first at @unil.bsky.social and now @unifr.bsky.social; with fantastic collaborators @ribeirocarlitos.bsky.social and @dahaniel.muench.bio.
rdcu.be/eRWuD
Great team effort, led by @enriberti.bsky.social first at @unil.bsky.social and now @unifr.bsky.social; with fantastic collaborators @ribeirocarlitos.bsky.social and @dahaniel.muench.bio.
Reposted by Michael Rera
Faire de la vulgarisation sur Instagram c’est quand même très ingrat
Je me casse la tête tous les jours pour des infos sourcées sur la création variétale et j’ai 100 followers
Des comptes de « scientifiques » qui surfent sur l’actualité est disent nimp : 150 k followers
Je me casse la tête tous les jours pour des infos sourcées sur la création variétale et j’ai 100 followers
Des comptes de « scientifiques » qui surfent sur l’actualité est disent nimp : 150 k followers
November 27, 2025 at 9:20 AM
Faire de la vulgarisation sur Instagram c’est quand même très ingrat
Je me casse la tête tous les jours pour des infos sourcées sur la création variétale et j’ai 100 followers
Des comptes de « scientifiques » qui surfent sur l’actualité est disent nimp : 150 k followers
Je me casse la tête tous les jours pour des infos sourcées sur la création variétale et j’ai 100 followers
Des comptes de « scientifiques » qui surfent sur l’actualité est disent nimp : 150 k followers
Reposted by Michael Rera
"Louise rentre la bouche en sang d’un week-end chez son père (...). Elle évoque à sa mère de nouveaux viols. Aux urgences, le médecin qui ausculte la petite fille envoie une nouvelle information préoccupante aux services de la protection de l’enfance. Sans effet" www.liberation.fr/societe/quan...
«Quand Louise parle, elle n’est pas entendue» : le combat d’une mère et sa fille de 4 ans, obligée d’aller chez son père accusé d’inceste
Après avoir dénoncé des agressions sexuelles rapportées par sa fille, Anna s’est notamment heurtée à la pénurie de personnel dédié à la protection de l’enfance et aux lenteurs de la justice.
www.liberation.fr
November 27, 2025 at 9:02 AM
"Louise rentre la bouche en sang d’un week-end chez son père (...). Elle évoque à sa mère de nouveaux viols. Aux urgences, le médecin qui ausculte la petite fille envoie une nouvelle information préoccupante aux services de la protection de l’enfance. Sans effet" www.liberation.fr/societe/quan...
November 27, 2025 at 9:33 AM
Reposted by Michael Rera
Chicago...
November 27, 2025 at 8:38 AM
Chicago...
Reposted by Michael Rera
Une liste de juifs désignés à la vindicte publique ?
Vous êtes sérieux ?
Tout va bien ?
Rien que le fait d'avoir eu l'idée hein... et d'un historien en plus...
Vous êtes sérieux ?
Tout va bien ?
Rien que le fait d'avoir eu l'idée hein... et d'un historien en plus...
a man in a military uniform is standing next to another man with #highcastle written in the corner
Alt: a man in a SS military uniform is standing next to another man in Waffen SS uniform saying "Fantastic" with #highcastle written in the corner
media.tenor.com
November 27, 2025 at 9:22 AM
Une liste de juifs désignés à la vindicte publique ?
Vous êtes sérieux ?
Tout va bien ?
Rien que le fait d'avoir eu l'idée hein... et d'un historien en plus...
Vous êtes sérieux ?
Tout va bien ?
Rien que le fait d'avoir eu l'idée hein... et d'un historien en plus...
Reposted by Michael Rera
How do new centromeres evolve while staying compatible with the division machinery?
Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore.
👉 doi.org/10.1038/s41586-025-09779-1
Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore.
👉 doi.org/10.1038/s41586-025-09779-1
November 26, 2025 at 4:21 PM
How do new centromeres evolve while staying compatible with the division machinery?
Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore.
👉 doi.org/10.1038/s41586-025-09779-1
Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore.
👉 doi.org/10.1038/s41586-025-09779-1
Reposted by Michael Rera
Dites @univ-amu.fr il y a votre professeur harceleur qui continue à harceler. Vous virez quand cet énergumène ?
November 27, 2025 at 9:24 AM
Dites @univ-amu.fr il y a votre professeur harceleur qui continue à harceler. Vous virez quand cet énergumène ?
Reposted by Michael Rera
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
November 27, 2025 at 8:47 AM
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
Reposted by Michael Rera
C'est pas les genoux de Bardella qui vont lâcher miraculeusement. La seule chance, c'est un contre discours. Des gros mots comme l'humanisme, la justice, le service public, l'attention portée aux fragiles. Et on l'assume au lieu de se faire emmener sur son putain de terrain boueux.
November 27, 2025 at 7:50 AM
C'est pas les genoux de Bardella qui vont lâcher miraculeusement. La seule chance, c'est un contre discours. Des gros mots comme l'humanisme, la justice, le service public, l'attention portée aux fragiles. Et on l'assume au lieu de se faire emmener sur son putain de terrain boueux.
Reposted by Michael Rera
November 27, 2025 at 7:21 AM
Reposted by Michael Rera
We’re so grateful for the readers and members who make our reporting possible — thank you for standing with us.
You fuel investigations that lead to real change, like these 🧵
You fuel investigations that lead to real change, like these 🧵
November 26, 2025 at 11:15 PM
We’re so grateful for the readers and members who make our reporting possible — thank you for standing with us.
You fuel investigations that lead to real change, like these 🧵
You fuel investigations that lead to real change, like these 🧵
Reposted by Michael Rera
Particles that enhance mRNA delivery could reduce vaccine dosage and costs.
#science #news
www.lifescience.net/news/6701/pa...
#science #news
www.lifescience.net/news/6701/pa...
Particles that enhance mRNA delivery could reduce vaccine dosage and costs
Using these nanoparticles to deliver a flu vaccine, researchers observed an effective immune response at a much lower dose.
www.lifescience.net
November 26, 2025 at 8:09 PM
Particles that enhance mRNA delivery could reduce vaccine dosage and costs.
#science #news
www.lifescience.net/news/6701/pa...
#science #news
www.lifescience.net/news/6701/pa...
Reposted by Michael Rera
You missed the point: They "received stem cells from a donor who only had one copy of the mutated gene, which means their cells do express CCR5, but at lower levels than usual."
November 26, 2025 at 6:26 PM
You missed the point: They "received stem cells from a donor who only had one copy of the mutated gene, which means their cells do express CCR5, but at lower levels than usual."
Reposted by Michael Rera
Evry time I see Kash Patel, my mind is stuck with his own character he wrote himself in children books about "the king".
November 26, 2025 at 6:19 PM
Evry time I see Kash Patel, my mind is stuck with his own character he wrote himself in children books about "the king".
Do they do it on purpose or does he always look like that?
Newly released emails show the FBI spent almost $1 million in overtime analyzing the Epstein files as part of an effort dubbed the “Special Redaction Project."
FBI’s Frantic Scramble to Redact Epstein Files Revealed
A trove of emails shows all-nighters and almost $1 million in overtime as Trumpworld debated releasing the Epstein files.
trib.al
November 26, 2025 at 6:13 PM
Do they do it on purpose or does he always look like that?
Reposted by Michael Rera
La gauche c'est mieux que la droite.
November 26, 2025 at 5:49 PM
La gauche c'est mieux que la droite.
Reposted by Michael Rera
Reposted by Michael Rera
A 60-year old man in Germany became the seventh person with HIV to be announced free of the virus after receiving a stem-cell transplant
go.nature.com/48C68Ib
go.nature.com/48C68Ib
Seventh patient ‘cured’ of HIV: why scientists are excited
A man in Germany is HIV-free after receiving stem cells that are not resistant to the virus.
go.nature.com
November 26, 2025 at 5:30 PM
A 60-year old man in Germany became the seventh person with HIV to be announced free of the virus after receiving a stem-cell transplant
go.nature.com/48C68Ib
go.nature.com/48C68Ib
Reposted by Michael Rera
Thrilled to share our new paper!
With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste.
Link @nature.com: www.nature.com/articles/s41...
With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste.
Link @nature.com: www.nature.com/articles/s41...
Evolution of taste processing shifts dietary preference - Nature
Calcium imaging of taste neurons and the ventral brain provides insight into evolutionary divergence of food choice in Drosophila species, supporting a role of sensorimotor processing in addition to p...
www.nature.com
November 26, 2025 at 4:33 PM
Thrilled to share our new paper!
With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste.
Link @nature.com: www.nature.com/articles/s41...
With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste.
Link @nature.com: www.nature.com/articles/s41...