MitoMavericks
@mitoscientists.bsky.social
A platform for scientists and
physicians to share and discuss important discoveries related to the role of mitochondria in health and to advance mitochondrial science as a cornerstone of improving human health. Please tag us to amplify your contributions.
physicians to share and discuss important discoveries related to the role of mitochondria in health and to advance mitochondrial science as a cornerstone of improving human health. Please tag us to amplify your contributions.
Pinned
mito:TT:gators
WhatsApp Group Invite
chat.whatsapp.com
Join mitoTT (mitochondria transfer and transplant) network. It comprises professionals from diverse sectors, including academia, biotech, pharma, investors, physicians, and entrepreneurs, to address challenges and create opportunities in the mitoTT field.
chat.whatsapp.com/BElX3Nn2swXA...
chat.whatsapp.com/BElX3Nn2swXA...
Reposted by MitoMavericks
A new collection of papers from #week5 on Mitochondria in Health & Disease! #MitochondrialDisease
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Among highlights
www.nature.com/articles/s41...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Among highlights
www.nature.com/articles/s41...
ALKB-1-dependent tRNA methylation is required for efficient paternal mitochondrial elimination - Nature Communications
For proper mitochondrial inheritance, paternal sperm mitochondria must be eliminated. Here, authors identify ALKB-1 mediated tRNA demethylation as essential for this clearance in Caenorhabditis elegan...
www.nature.com
February 1, 2026 at 12:16 PM
A new collection of papers from #week5 on Mitochondria in Health & Disease! #MitochondrialDisease
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Among highlights
www.nature.com/articles/s41...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Among highlights
www.nature.com/articles/s41...
Reposted by MitoMavericks
A new collection of papers on Mitochondria in Health and Disease! #week3 #MitochondrialDisorders
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities
January 25, 2026 at 3:15 PM
A new collection of papers on Mitochondria in Health and Disease! #week3 #MitochondrialDisorders
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities
Reposted by MitoMavericks
Latest collection of papers on mitochondria in health and disease! #MitochondrialDisease #week3
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
www.nature.com/articles/s42...
Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production - Nature Metabolism
Hexokinase detachment from the outer mitochondrial membrane is shown to support aerobic glycolysis in cancer cells. Differential localization of the HK1 isoform to the outer mitochondrial membrane, co...
www.nature.com
January 18, 2026 at 12:36 PM
Latest collection of papers on mitochondria in health and disease! #MitochondrialDisease #week3
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
www.nature.com/articles/s42...
Reposted by MitoMavericks
I asked AI to describe my contribution to the mitochondrial field. Received this. It's quite impressive and pretty accurate.
January 16, 2026 at 4:54 AM
I asked AI to describe my contribution to the mitochondrial field. Received this. It's quite impressive and pretty accurate.
Reposted by MitoMavericks
Excited to speak at the symposium “Artificial Intelligence in Mitochondrial Medicine”
🧬 Exploring how AI is transforming mitochondrial medicine
📍 Pisa, Italy | 🏨 Hotel Galilei
📅 Jan 23, 2026
#AIinMedicine #MitochondrialMedicine #DigitalHealth #PrecisionMedicine
🧬 Exploring how AI is transforming mitochondrial medicine
📍 Pisa, Italy | 🏨 Hotel Galilei
📅 Jan 23, 2026
#AIinMedicine #MitochondrialMedicine #DigitalHealth #PrecisionMedicine
January 12, 2026 at 5:01 AM
Excited to speak at the symposium “Artificial Intelligence in Mitochondrial Medicine”
🧬 Exploring how AI is transforming mitochondrial medicine
📍 Pisa, Italy | 🏨 Hotel Galilei
📅 Jan 23, 2026
#AIinMedicine #MitochondrialMedicine #DigitalHealth #PrecisionMedicine
🧬 Exploring how AI is transforming mitochondrial medicine
📍 Pisa, Italy | 🏨 Hotel Galilei
📅 Jan 23, 2026
#AIinMedicine #MitochondrialMedicine #DigitalHealth #PrecisionMedicine
Reposted by MitoMavericks
Last 2 weeks of research papers relevant to #MitochondrialDisease!
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
Mitochondrial control of fuel switching via carnitine biosynthesis
Environmental adaptation often involves a shift in energy utilization toward mitochondrial fatty acid oxidation, which requires carnitine. Besides dietary sources of animal origin, carnitine biosynthe...
www.science.org
January 11, 2026 at 12:53 PM
Last 2 weeks of research papers relevant to #MitochondrialDisease!
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
Reposted by MitoMavericks
Reviews/Perspectives Top #Citations 2025: 🥇🧪
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Recommendations for mitochondria transfer and transplantation nomenclature and characterization - Nature Metabolism
This Consensus Statement provides a nomenclature framework and experimental recommendations for studying mitochondrial transfer and transplantation.
www.nature.com
December 31, 2025 at 6:01 PM
Reviews/Perspectives Top #Citations 2025: 🥇🧪
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Reposted by MitoMavericks
Reviews/Perspectives Top #Altmetric 2025: 🥇🧪
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Recommendations for mitochondria transfer and transplantation nomenclature and characterization - Nature Metabolism
This Consensus Statement provides a nomenclature framework and experimental recommendations for studying mitochondrial transfer and transplantation.
www.nature.com
December 31, 2025 at 7:02 PM
Reviews/Perspectives Top #Altmetric 2025: 🥇🧪
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Jonathan Brestoff (Washington U Dept Med), Keshav Singh (@mitoscientist.bsky.social, U Alabama) et al.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization
Reposted by MitoMavericks
🌹🌹May all that is beautiful and meaningful and brings you and your family joy be yours throughout the coming year! Wish you a very happy new year!🌹🌹
December 31, 2025 at 3:06 PM
🌹🌹May all that is beautiful and meaningful and brings you and your family joy be yours throughout the coming year! Wish you a very happy new year!🌹🌹
Reposted by MitoMavericks
End-of-year selection of papers on #MitochondrialDisease! 📚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social @mitoscientists.bsky.social
Have a great 2026! ✨
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social @mitoscientists.bsky.social
Have a great 2026! ✨
December 28, 2025 at 2:45 PM
End-of-year selection of papers on #MitochondrialDisease! 📚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social @mitoscientists.bsky.social
Have a great 2026! ✨
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social @mitoscientists.bsky.social
Have a great 2026! ✨
Reposted by MitoMavericks
Reposted by MitoMavericks
Mitochondria are among nature's most remarkable gifts to us. These tiny powerhouses are essential for providing
energy and stand at the forefront of anti-aging science, serving as the driving
force behind strategies to promote healthy longevity.
energy and stand at the forefront of anti-aging science, serving as the driving
force behind strategies to promote healthy longevity.
December 24, 2025 at 6:14 PM
Mitochondria are among nature's most remarkable gifts to us. These tiny powerhouses are essential for providing
energy and stand at the forefront of anti-aging science, serving as the driving
force behind strategies to promote healthy longevity.
energy and stand at the forefront of anti-aging science, serving as the driving
force behind strategies to promote healthy longevity.
Reposted by MitoMavericks
🍃 🏛️ ✏️ 🧪 Forgotten NIH Required Attachments for Applications
Dec 22, 2025
Dec 22, 2025
What if I Forgot to Include a Required Attachment of an Application? | Grants & Funding
grants.nih.gov
December 23, 2025 at 11:35 AM
🍃 🏛️ ✏️ 🧪 Forgotten NIH Required Attachments for Applications
Dec 22, 2025
Dec 22, 2025
Reposted by MitoMavericks
Powerful short documentary about the researchers affected by NIH grant terminations and broad extortion of universities.
youtu.be/DaTOmUZHeik
1/2
youtu.be/DaTOmUZHeik
1/2
Death By a Thousand Cuts Capstone Archive Submission
YouTube video by Usha Sookai
youtu.be
December 23, 2025 at 1:30 PM
Powerful short documentary about the researchers affected by NIH grant terminations and broad extortion of universities.
youtu.be/DaTOmUZHeik
1/2
youtu.be/DaTOmUZHeik
1/2
Reposted by MitoMavericks
Christmas edition🎄of #MitochondrialDisease collection of papers! 🎁 📚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Fuel your mitos well and happy holidays!
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Fuel your mitos well and happy holidays!
December 21, 2025 at 2:53 PM
Christmas edition🎄of #MitochondrialDisease collection of papers! 🎁 📚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Fuel your mitos well and happy holidays!
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Fuel your mitos well and happy holidays!
Reposted by MitoMavericks
It's an honor to see Yuva Biosciences and our contributions in the field featured in this mitochondrial story in The Washington Post today.
Beating back the effects of aging by "supercharging cells". Here's my story on the Washington Post home page: www.washingtonpost.com/science/2025...
The quest to slow aging leads scientists into the powerhouse of cells
Scientists have developed a new method to boost the energy of aging or damaged cells, an innovation that could improve treatment of a variety of conditions.
www.washingtonpost.com
December 8, 2025 at 11:48 PM
It's an honor to see Yuva Biosciences and our contributions in the field featured in this mitochondrial story in The Washington Post today.
Reposted by MitoMavericks
Such a great collection of papers on #mitochondrialdisease from #week49! 📚 Congratulations to all authors! biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social
Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Wang et al
@biomednews.bsky.social @mitoscientist.bsky.social
Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Wang et al
December 7, 2025 at 2:54 PM
Such a great collection of papers on #mitochondrialdisease from #week49! 📚 Congratulations to all authors! biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social
Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Wang et al
@biomednews.bsky.social @mitoscientist.bsky.social
Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Wang et al
Reposted by MitoMavericks
#mitochondrialdisease collection of papers from #week48! 📚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Inhibition of oligomeric BAX by an anti-apoptotic dimer
Newman et al
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Inhibition of oligomeric BAX by an anti-apoptotic dimer
Newman et al
November 30, 2025 at 12:38 PM
#mitochondrialdisease collection of papers from #week48! 📚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Inhibition of oligomeric BAX by an anti-apoptotic dimer
Newman et al
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
Inhibition of oligomeric BAX by an anti-apoptotic dimer
Newman et al
Reposted by MitoMavericks
Rich collections of papers on #mitochondrialdisease from the last 2 weeks! 📚
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social
@gavinmcstay.bsky.social
Demethoxy-CoQ and NUDT5 in nucleotide synthesis
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social
@gavinmcstay.bsky.social
Demethoxy-CoQ and NUDT5 in nucleotide synthesis
www.nature.com/articles/s42...
Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis - Nature Metabolism
A uridine-sensitized CRISPR-Cas9 screening identifies demethoxy-CoQ as an alternative electron acceptor in the absence of CoQ, and NUDT5 as a regulator of de novo pyrimidine synthesis via its interact...
www.nature.com
November 23, 2025 at 11:59 AM
Rich collections of papers on #mitochondrialdisease from the last 2 weeks! 📚
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social
@gavinmcstay.bsky.social
Demethoxy-CoQ and NUDT5 in nucleotide synthesis
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social
@gavinmcstay.bsky.social
Demethoxy-CoQ and NUDT5 in nucleotide synthesis
www.nature.com/articles/s42...
Reposted by MitoMavericks
A new collection of papers on #mitochondrialdisease from #week45! 📚 💚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito complex III-derived ROS amplify immunometab changes in astrocytes and promote dementia
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito complex III-derived ROS amplify immunometab changes in astrocytes and promote dementia
www.nature.com/articles/s42...
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology - Nature Metabolism
Barnett et al. disentangle the differential contribution of mitochondrial complex I- and complex III-derived ROS to astrocytic function, with CIII-derived ROS being a major driver of neuroinflammatory...
www.nature.com
November 9, 2025 at 12:53 PM
A new collection of papers on #mitochondrialdisease from #week45! 📚 💚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito complex III-derived ROS amplify immunometab changes in astrocytes and promote dementia
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito complex III-derived ROS amplify immunometab changes in astrocytes and promote dementia
www.nature.com/articles/s42...
Reposted by MitoMavericks
Great collections of papers on #mitochondrialdisease from #week42 and #week43! 📚
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito & psy stress regulation of FGF21 in humans
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito & psy stress regulation of FGF21 in humans
www.nature.com/articles/s42...
Mitochondrial and psychosocial stress-related regulation of FGF21 in humans - Nature Metabolism
FGF21 levels increase in response to acute mental stress in individuals with impaired mitochondrial OxPhos capacity, and correlate with stress-related neuroendocrine hormones and trait-level psychosoc...
www.nature.com
October 26, 2025 at 10:36 AM
Great collections of papers on #mitochondrialdisease from #week42 and #week43! 📚
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito & psy stress regulation of FGF21 in humans
www.nature.com/articles/s42...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mito & psy stress regulation of FGF21 in humans
www.nature.com/articles/s42...
Reposted by MitoMavericks
Happy Diwali-The Festival of Lights
As we celebrate this beautiful festival that
symbolizes the triumph of light over darkness, knowledge over ignorance, and good over evil - let us rekindle the light within us to create a brighter future for all.
#Diwali #diwalicelebration #deepavali
As we celebrate this beautiful festival that
symbolizes the triumph of light over darkness, knowledge over ignorance, and good over evil - let us rekindle the light within us to create a brighter future for all.
#Diwali #diwalicelebration #deepavali
October 20, 2025 at 3:21 AM
Happy Diwali-The Festival of Lights
As we celebrate this beautiful festival that
symbolizes the triumph of light over darkness, knowledge over ignorance, and good over evil - let us rekindle the light within us to create a brighter future for all.
#Diwali #diwalicelebration #deepavali
As we celebrate this beautiful festival that
symbolizes the triumph of light over darkness, knowledge over ignorance, and good over evil - let us rekindle the light within us to create a brighter future for all.
#Diwali #diwalicelebration #deepavali
Reposted by MitoMavericks
Fresh selection of papers on #MitochondrialDisease from #week41! 📚 💚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
www.science.org/doi/10.1126/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
www.science.org/doi/10.1126/...
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times as...
www.science.org
October 12, 2025 at 11:06 AM
Fresh selection of papers on #MitochondrialDisease from #week41! 📚 💚
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
www.science.org/doi/10.1126/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
www.science.org/doi/10.1126/...