Michael Boucher
mjboucher.bsky.social
Michael Boucher
@mjboucher.bsky.social
Microbiologist studying human fungal pathogens | New PI at the Wadsworth Center, New York State Department of Health
Reposted by Michael Boucher
The University at Albany Biomedical Sciences Department is hiring at the Assistant Professor level. We are looking for researchers at the intersection of infectious disease and artificial intelligence:
albany.interviewexchange.com/jobofferdeta...
#infectiousdisease #artificialintelligence
albany.interviewexchange.com
November 18, 2025 at 10:45 PM
Reposted by Michael Boucher
Faculty search at UAlbany targeting folks broadly applying AI/ML to infectious disease research!! Please RT 🙏
albany.interviewexchange.com/jobofferdeta...
November 18, 2025 at 11:15 PM
Deadline to apply for a postdoctoral position in my lab has been corrected--applications will be accepted until October 28.

healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...
Research Affiliate I (Post Doctoral)
Applications to be submitted by October 28, 2025 Compensation Grade: P99 (Research Affiliate I) Compensation Details: Minimum: $62,353.20 - Maximum: $62,353.20 Annually Positions with a designated wor...
healthresearch.wd1.myworkdayjobs.com
October 14, 2025 at 8:48 PM
My lab is hiring a postdoc! Official job ad and application instructions here:

healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...

Current deadline says October 13, but this will be extended to be open for ~2 weeks.
Research Affiliate I (Post Doctoral)
Applications to be submitted by October 13, 2025 Compensation Grade: P99 (Research Affiliate I) Compensation Details: Minimum: $62,353.20 - Maximum: $62,353.20 Annually Positions with a designated wor...
healthresearch.wd1.myworkdayjobs.com
October 10, 2025 at 6:44 PM
Reposted by Michael Boucher
We just published new selectable markers for C. neoformans, bringing the total up to 7. All in CRiSPR-Cas9 compatible plasmids.

journals.asm.org/doi/10.1128/...
CRISPR/Cas9-compatible plasmids enabling seven dominant genetic selection methods for the human fungal pathogen Cryptococcus neoformans | Microbiology Spectrum
Cryptococcus neoformans is the top-ranked World Health Organization priority fungal pathogen due to its widespread distribution and inadequate treatment options. Additionally, as a basidiomycete yeast...
journals.asm.org
September 26, 2025 at 2:31 PM
Small side-project from my postdoctoral work with @hitenmadhani.bsky.social. We found that blasticidin S can select for Cryptococcus transformants, and made CRISPR-compatible plasmids for other existing markers. Now 7 dominant genetic selection methods in total!

journals.asm.org/doi/10.1128/...
CRISPR/Cas9-compatible plasmids enabling seven dominant genetic selection methods for the human fungal pathogen Cryptococcus neoformans | Microbiology Spectrum
Cryptococcus neoformans is the top-ranked World Health Organization priority fungal pathogen due to its widespread distribution and inadequate treatment options. Additionally, as a basidiomycete yeast...
journals.asm.org
September 26, 2025 at 9:39 PM
Reposted by Michael Boucher
Leishmaniasis is 95% fatal if untreated — yet it’s still overlooked, and media coverage is low.

Our new report shows what gets decision-makers to pay attention ⤵️
wellcomeopenresearch.org/documents/10...
August 19, 2025 at 9:21 AM
Reposted by Michael Boucher
New in #G3journal: @hitenmadhani.bsky.social and the team present new methods and strains for high-efficiency homology-dependent genome editing in Cryptococcus neoformans, a budding #yeast that is the most common cause of fungal meningitis in humans.

Read more: buff.ly/dQRKrOJ
August 15, 2025 at 4:12 PM
New PI day 1!
August 14, 2025 at 10:57 PM
Reposted by Michael Boucher
🍄Mark your calendars for March 17-22, 2026 for #Fungal26! Registration will open October 25, 2025. We can’t wait to see you at Asilomar in absolutely beautiful Pacific Grove, California. Start planning today!

🔗Stay updated on all the important information at buff.ly/BjAlE2j.
August 11, 2025 at 6:02 PM
Our work to functionally map the Cryptococcus genome is now "officially" out in Cell!
July 24, 2025 at 7:38 PM
Someone's settled in for her cross-country road trip
July 19, 2025 at 9:46 PM
Reposted by Michael Boucher
Hello everyone! I am pleased to share information on the first ever Computational Structural Virology Symposium, conducted August 4th on zoom and highlighting work in this emerging field. You can register for this event here: forms.gle/CNiqskMwQEuV.... Please re-post!
June 12, 2025 at 8:31 PM
My postdoctoral work with @hitenmadhani.bsky.social is now online at @cp-cell.bsky.social! We profiled the fitness of >4300 Cryptococcus neoformans deletion strains in >140 conditions, identifying unexpected mammalian-like biology and drivers of fungal pathogenesis.

www.cell.com/cell/fulltex...
Phenotypic landscape of an invasive fungal pathogen reveals its unique biology
The construction and high-precision fitness profiling of a C. neoformans knockout library reveals a high-resolution functional map of its genome and allowed for the identification of fungal analogs of...
www.cell.com
June 11, 2025 at 4:00 PM
Reposted by Michael Boucher
#TheLastOfUs: A fungus that actually infects the human brain 🧠

A recent #G3journal paper from @hitenmadhani.bsky.social and team presents a valuable auxin-inducible genetic toolkit for conditional mutation in the fungal pathogen Cryptococcus neoformans, which can cause meningitis: buff.ly/rIkC09R
June 5, 2025 at 6:03 PM
Reposted by Michael Boucher
Warp speed genetics!

We have just published another methods paper, which demonstrates how to make short-homology genome edits in Cryptococcus neoformans with exceptionally high efficiency.

Kudos to Matt, Sanjita, and Manning!

academic.oup.com/g3journal/ar...
Near 100% efficient homology-dependent genome engineering in the human fungal pathogen Cryptococcus neoformans
Abstract. We recently described CRISPR/Cas9-based short homology-dependent genome engineering in the human fungal pathogen Cryptococcus neoformans, a haplo
academic.oup.com
June 4, 2025 at 6:06 PM
Come join me as a new PI at the Wadsworth Center!
The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases!
www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/
This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!)
Reposts appreciated 🙏
June 4, 2025 at 1:53 AM
Thanks to @hitenmadhani.bsky.social and the many coauthors who made this work possible!
Who knows what the future holds, but today we’ll celebrate acceptance of Mike’s epic Cell paper and with some Veuve Clicquot!
@michaelboucher.bsky.social
May 17, 2025 at 5:18 PM
Really excited to share that I'll start my research lab at the Wadsworth Center with the New York State Department of Health in August 2025! My group will use functional genomics to study how fungal pathogens have repurposed machinery from their environmental lifestyles for mammalian infection!
May 9, 2025 at 7:43 PM
Reposted by Michael Boucher
Our small but important technical advance for conditional mutation in Cryptococcus neoformans. Combined with some other technical advances (like 100% efficient HDR), this makes working on this yeast as easy as working on S. cerevisiae. tinyurl.com/yzhjr45u
An auxin-inducible degron system for conditional mutation in the fungal meningitis pathogen Cryptococcus neoformans
Abstract. Cryptococcus neoformans is the top-ranked W.H.O. fungal priority pathogen, but tools for generating conditional mutations are limited. Auxin-indu
academic.oup.com
April 8, 2025 at 6:05 PM
Reposted by Michael Boucher
We have another opening for a fully funded #PhDposition in the Beusch lab (www.beuschlab.org) at the University of Würzburg! If you or someone you know is curious about #splicing, please apply or contact me for more information. (Official advertisement tba soon.) #RNAsky #RNAbiology
December 19, 2024 at 10:43 PM