Michael Prigge
@mjprigge.bsky.social
Plant biologist at UCSD (how auxin regulates transcription across land plants, from receptors to pol II and the steps in between). Mostly, moss⬌Arabidopsis. Grew up in Minnesota, attended/worked at UMinn, UO, UM, and IU.
Pinned
Michael Prigge
@mjprigge.bsky.social
· Apr 11
Some auxin-related reading for the week-end: ARFs are degraded, too.
- "Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants" rdcu.be/ehnOT
- "ARF degradation defines a deeply conserved step in auxin response" rdcu.be/ehnPa
#PlantScience
- "Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants" rdcu.be/ehnOT
- "ARF degradation defines a deeply conserved step in auxin response" rdcu.be/ehnPa
#PlantScience
I am very happy to see this story published! This was a wonderful collaboration between the @mestelle.bsky.social lab (@ucsandiego.bsky.social) on the moss side, Annis Richardson’s lab on the maize side, and @luciastrader.bsky.social lab’s help throughout.
#plantscience #auxin
#plantscience #auxin
Reposted by Michael Prigge
Discover how roots “feel” gravity:
Our latest PNAS paper shows that root gravitropism isn’t just on/off, but is unified and angle-dependent, tied to auxin shifts driven by PIN protein and statolith behaviour in columella cells.
Read more: tinyurl.com/22awa3pf
Our latest PNAS paper shows that root gravitropism isn’t just on/off, but is unified and angle-dependent, tied to auxin shifts driven by PIN protein and statolith behaviour in columella cells.
Read more: tinyurl.com/22awa3pf
Angle dependence as a unifying feature of root graviresponse modules | PNAS
Gravitropism, the patterning of postembryonic growth in relation to the gravity vector,
allows plants to optimize the use of limited and nonhomogen...
www.pnas.org
November 20, 2025 at 1:45 PM
Discover how roots “feel” gravity:
Our latest PNAS paper shows that root gravitropism isn’t just on/off, but is unified and angle-dependent, tied to auxin shifts driven by PIN protein and statolith behaviour in columella cells.
Read more: tinyurl.com/22awa3pf
Our latest PNAS paper shows that root gravitropism isn’t just on/off, but is unified and angle-dependent, tied to auxin shifts driven by PIN protein and statolith behaviour in columella cells.
Read more: tinyurl.com/22awa3pf
This table from a 1969 paper on moss from Folke Skoog’s lab has lived in the back of my head for the almost 20 years since I noticed it. I think it might finally be getting evicted.
They showed that Funaria 3D bud formation was correlated with a huge jump in guanine bases in RNA. (1/6)
They showed that Funaria 3D bud formation was correlated with a huge jump in guanine bases in RNA. (1/6)
November 13, 2025 at 12:33 AM
This table from a 1969 paper on moss from Folke Skoog’s lab has lived in the back of my head for the almost 20 years since I noticed it. I think it might finally be getting evicted.
They showed that Funaria 3D bud formation was correlated with a huge jump in guanine bases in RNA. (1/6)
They showed that Funaria 3D bud formation was correlated with a huge jump in guanine bases in RNA. (1/6)
Reposted by Michael Prigge
Are you looking for a PhD in Plant Science? Check our our project on barley canopy architecture. Combine genetics and physics to understand how awns influence barley grain development. Find out more here: lnkd.in/eWhWammJ Apply by 14th December. #PhDPosition
#PlantSci @instmolplantsci.bsky.social
#PlantSci @instmolplantsci.bsky.social
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
November 10, 2025 at 1:22 PM
Are you looking for a PhD in Plant Science? Check our our project on barley canopy architecture. Combine genetics and physics to understand how awns influence barley grain development. Find out more here: lnkd.in/eWhWammJ Apply by 14th December. #PhDPosition
#PlantSci @instmolplantsci.bsky.social
#PlantSci @instmolplantsci.bsky.social
Reposted by Michael Prigge
From Knowable Magazine: How #Arabidopsis thaliana, a humble weed, became a superstar of plant biology | Knowable Magazine knowablemagazine.org/content/arti...
How a humble weed became a superstar of biology
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
knowablemagazine.org
November 5, 2025 at 4:54 PM
From Knowable Magazine: How #Arabidopsis thaliana, a humble weed, became a superstar of plant biology | Knowable Magazine knowablemagazine.org/content/arti...
After reading about milkweed’s cardiac glycosides in @nkwhiteman.bsky.social ‘s book, I was surprised to see people eating stew with milkweed floral buds in tonight’s episode of Tony Shalhoub Breaking Bread. Does the toxin break down in the heat? Or is it absent from buds?
November 3, 2025 at 11:11 AM
After reading about milkweed’s cardiac glycosides in @nkwhiteman.bsky.social ‘s book, I was surprised to see people eating stew with milkweed floral buds in tonight’s episode of Tony Shalhoub Breaking Bread. Does the toxin break down in the heat? Or is it absent from buds?
Reposted by Michael Prigge
Excited to share a recent review from our team in Physiologia Plantarum digging into how effectors modulate TPL/TPR family proteins through competition with endogenous EAR motif containing proteins: The TPX family of co‐repressors: a hub amidst the hubbub onlinelibrary.wiley.com/doi/10.1111/...
The TPX family of co‐repressors: a hub amidst the hubbub
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onlinelibrary.wiley.com
October 21, 2025 at 9:08 PM
Excited to share a recent review from our team in Physiologia Plantarum digging into how effectors modulate TPL/TPR family proteins through competition with endogenous EAR motif containing proteins: The TPX family of co‐repressors: a hub amidst the hubbub onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Michael Prigge
Really excited to share the pre-print of my first paper! It details the computational method we used to identify uncharacterized metabolites along the developmental gradient of maize roots, I hope you find it interesting! 🌱🌽
Computational method for mapping mass signatures along developmental gradients reveals a novel role for a monosaccharide tetrose in maize salt-stress response. https://www.biorxiv.org/content/10.1101/2025.09.22.677919v1
September 28, 2025 at 7:26 PM
Really excited to share the pre-print of my first paper! It details the computational method we used to identify uncharacterized metabolites along the developmental gradient of maize roots, I hope you find it interesting! 🌱🌽
Reposted by Michael Prigge
Standardizing models across a field so that everyone gets the same answer is only helpful if the answer is (1) correct and (2) generalizable.
Otherwise it’s a regulated circle jerk.
Otherwise it’s a regulated circle jerk.
October 17, 2025 at 6:52 PM
Standardizing models across a field so that everyone gets the same answer is only helpful if the answer is (1) correct and (2) generalizable.
Otherwise it’s a regulated circle jerk.
Otherwise it’s a regulated circle jerk.
Reposted by Michael Prigge
A message from the frog resistance
youtu.be/bw5zxdSObso
youtu.be/bw5zxdSObso
A Message From The Frog Resistance
YouTube video by The Late Show with Stephen Colbert
youtu.be
October 14, 2025 at 2:52 AM
A message from the frog resistance
youtu.be/bw5zxdSObso
youtu.be/bw5zxdSObso
Reposted by Michael Prigge
Unlocking #grass #leaf development: foundations for tunable #cereal design
📖 buff.ly/08NS8jV
#TansleyReview by McAllister et al.
@drannisr.bsky.social @hildenelissen.bsky.social @WileyPlantSci
#PlantSci #genetics
Figure credit BioRender: Hilde, Nelissen (2025) buff.ly/uhRFPbx.
📖 buff.ly/08NS8jV
#TansleyReview by McAllister et al.
@drannisr.bsky.social @hildenelissen.bsky.social @WileyPlantSci
#PlantSci #genetics
Figure credit BioRender: Hilde, Nelissen (2025) buff.ly/uhRFPbx.
Leaf development engineering challenges and opportunities.
nph.onlinelibrary.wiley.com
October 5, 2025 at 11:30 AM
Unlocking #grass #leaf development: foundations for tunable #cereal design
📖 buff.ly/08NS8jV
#TansleyReview by McAllister et al.
@drannisr.bsky.social @hildenelissen.bsky.social @WileyPlantSci
#PlantSci #genetics
Figure credit BioRender: Hilde, Nelissen (2025) buff.ly/uhRFPbx.
📖 buff.ly/08NS8jV
#TansleyReview by McAllister et al.
@drannisr.bsky.social @hildenelissen.bsky.social @WileyPlantSci
#PlantSci #genetics
Figure credit BioRender: Hilde, Nelissen (2025) buff.ly/uhRFPbx.
Reposted by Michael Prigge
Really honest, beautifully wrought piece. Karly is the queen of the telling detail. www.vulture.com/article/wedn...
‘I’m Poking Roadkill With a Stick. Making It Twitch.’
Wednesday’s Karly Hartzman and MJ Lenderman broke up. A month later, she writes in this personal essay, she had to record a love song for him.
www.vulture.com
October 8, 2025 at 6:39 PM
Really honest, beautifully wrought piece. Karly is the queen of the telling detail. www.vulture.com/article/wedn...
Reposted by Michael Prigge
Check out our new review in JXB:
tinyurl.com/yta6fd5b
@pablidopsis.bsky.social and I write about the cell's decision between division and differentiation. 🌱 What factors promote one or the other in different cell types? 🤔 Are they really mutually exclusive?
tinyurl.com/yta6fd5b
@pablidopsis.bsky.social and I write about the cell's decision between division and differentiation. 🌱 What factors promote one or the other in different cell types? 🤔 Are they really mutually exclusive?
Validate User
tinyurl.com
October 1, 2025 at 8:55 AM
Check out our new review in JXB:
tinyurl.com/yta6fd5b
@pablidopsis.bsky.social and I write about the cell's decision between division and differentiation. 🌱 What factors promote one or the other in different cell types? 🤔 Are they really mutually exclusive?
tinyurl.com/yta6fd5b
@pablidopsis.bsky.social and I write about the cell's decision between division and differentiation. 🌱 What factors promote one or the other in different cell types? 🤔 Are they really mutually exclusive?
Nice write-up about RUBY in our university newsletter:
today.ucsd.edu/story/seeing...
today.ucsd.edu/story/seeing...
Seeing Red: A UC San Diego Invention is Transforming the Way Scientists Track Genes
UC San Diego biologists have created a transformative new way to monitor genes. The game-changing tool known as RUBY is an inexpensive, easy-to-use technology that allows researchers to visualize gene...
today.ucsd.edu
September 30, 2025 at 11:50 PM
Nice write-up about RUBY in our university newsletter:
today.ucsd.edu/story/seeing...
today.ucsd.edu/story/seeing...
Reposted by Michael Prigge
🌱📖 RESEARCH 🌱📖
Bascom et al. used CRIPSR/Cas9 to produce a septuple AUXIN RESPONSE FACTOR mutant in the model bryophyte Physcomitrium patens , revealing the developmental consequences of the complete loss of auxin-mediated gene activation 🌱📖
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Bascom et al. used CRIPSR/Cas9 to produce a septuple AUXIN RESPONSE FACTOR mutant in the model bryophyte Physcomitrium patens , revealing the developmental consequences of the complete loss of auxin-mediated gene activation 🌱📖
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
September 29, 2025 at 10:42 AM
🌱📖 RESEARCH 🌱📖
Bascom et al. used CRIPSR/Cas9 to produce a septuple AUXIN RESPONSE FACTOR mutant in the model bryophyte Physcomitrium patens , revealing the developmental consequences of the complete loss of auxin-mediated gene activation 🌱📖
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Bascom et al. used CRIPSR/Cas9 to produce a septuple AUXIN RESPONSE FACTOR mutant in the model bryophyte Physcomitrium patens , revealing the developmental consequences of the complete loss of auxin-mediated gene activation 🌱📖
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Reposted by Michael Prigge
🌱🧬 INSIGHT 🧬🌱
Complete loss of A-ARF activity in bryophytes reveals a role for auxin-adjacent regulatory networks – Flores-Sandoval & Bowman comment on an original research article by Bascom et al.
📝 Insight: doi.org/10.1093/jxb/...
🔬 Research: doi.org/10.1093/jxb/...
#PlantScience 🧪
Complete loss of A-ARF activity in bryophytes reveals a role for auxin-adjacent regulatory networks – Flores-Sandoval & Bowman comment on an original research article by Bascom et al.
📝 Insight: doi.org/10.1093/jxb/...
🔬 Research: doi.org/10.1093/jxb/...
#PlantScience 🧪
September 22, 2025 at 1:32 PM
🌱🧬 INSIGHT 🧬🌱
Complete loss of A-ARF activity in bryophytes reveals a role for auxin-adjacent regulatory networks – Flores-Sandoval & Bowman comment on an original research article by Bascom et al.
📝 Insight: doi.org/10.1093/jxb/...
🔬 Research: doi.org/10.1093/jxb/...
#PlantScience 🧪
Complete loss of A-ARF activity in bryophytes reveals a role for auxin-adjacent regulatory networks – Flores-Sandoval & Bowman comment on an original research article by Bascom et al.
📝 Insight: doi.org/10.1093/jxb/...
🔬 Research: doi.org/10.1093/jxb/...
#PlantScience 🧪
A friend of mine has a preprint out with an ingenious method to directly generate collections of NILs surrounding a locus or a collection of loci. They used the yeast KO collection, but it’d be cool to adapt for mapping traits in plants.
High-resolution, genotype-free mapping of genetic variation with CRI-SPA-Map https://www.biorxiv.org/content/10.1101/2025.09.16.676640v1
September 19, 2025 at 11:05 PM
A friend of mine has a preprint out with an ingenious method to directly generate collections of NILs surrounding a locus or a collection of loci. They used the yeast KO collection, but it’d be cool to adapt for mapping traits in plants.
Reposted by Michael Prigge
Reposted by Michael Prigge
Did you know that there is a cell cycle duration gradient in plant root meristem? New story by joining forces between Plant dynamics lab and Crisanto Gutiérrez & Bénédicte Desvoyes lab @cbgpmadrid.bsky.social @cbm-csic-uam.bsky.social #Plants #roots #cellcycle www.nature.com/articles/s41...
Stem cell regulators drive a G1 duration gradient during plant root development - Nature Plants
A positional and developmentally regulated cell cycle duration gradient exists in the root meristem whereby the G1 phase is very long close to the stem cell niche. This relies on the interplay of PLET...
www.nature.com
September 18, 2025 at 10:10 AM
Did you know that there is a cell cycle duration gradient in plant root meristem? New story by joining forces between Plant dynamics lab and Crisanto Gutiérrez & Bénédicte Desvoyes lab @cbgpmadrid.bsky.social @cbm-csic-uam.bsky.social #Plants #roots #cellcycle www.nature.com/articles/s41...
Reposted by Michael Prigge
Please repost and spread the word! 🙂
September 15, 2025 at 3:00 PM
Please repost and spread the word! 🙂
Took some time off to visit family and to see Courtney Barnett for the first time this weekend. Amazing show! (Picture from @tbobrowsky.bsky.social blows all my phone-snaps out of the water.)
September 7, 2025 at 6:17 AM
Took some time off to visit family and to see Courtney Barnett for the first time this weekend. Amazing show! (Picture from @tbobrowsky.bsky.social blows all my phone-snaps out of the water.)
Reposted by Michael Prigge
Diversification of functional requirements for proteolysis of Auxin Response Factors https://www.biorxiv.org/content/10.1101/2025.09.03.673984v1
September 5, 2025 at 1:05 AM
Diversification of functional requirements for proteolysis of Auxin Response Factors https://www.biorxiv.org/content/10.1101/2025.09.03.673984v1
Reposted by Michael Prigge
Reposted by Michael Prigge
Here it is! Epidermal cells in the root can figure out if they are covered by the root cap or not using mechanical signals! Thanks to @ckirchhelle.bsky.social, @moritznowack.bsky.social, @nathan-german.bsky.social Annamaria Kiss and all the others!
Plant cells at the organ surface use mechanical cues to activate a specific growth control programme https://www.biorxiv.org/content/10.1101/2025.08.25.672229v1
August 27, 2025 at 9:43 PM
Here it is! Epidermal cells in the root can figure out if they are covered by the root cap or not using mechanical signals! Thanks to @ckirchhelle.bsky.social, @moritznowack.bsky.social, @nathan-german.bsky.social Annamaria Kiss and all the others!
Reposted by Michael Prigge
Did America really need this product?
August 22, 2025 at 6:02 PM
Did America really need this product?
Reposted by Michael Prigge
Ok, hear me out, here's the plan:
August 19, 2025 at 11:08 AM
Ok, hear me out, here's the plan: