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Mary Prahl, MD @mkprahl.bsky.social · 17d

So happy to see this study and the positive results!

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Mary Prahl, MD @mkprahl.bsky.social · Sep 9

So great to see this study out. Raises the bar for pregnancy related vaccine research

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Reposted by Mary Prahl, MD

BK. Titanji @boghuma.bsky.social · Sep 9

Important and timely study
Pregnant women face higher risks from Ebola: maternal mortality up to 89%, and nearly all pregnancies lost. Until now, they’ve been excluded from Ebola vaccine trials. A landmark phase 3 RCT in Rwanda changes [email protected]
www.nature.com/articles/s41...

Heterologous two-dose Ebola vaccine regimen in pregnant women in Rwanda: a randomized controlled phase 3 trial - Nature Medicine

In this phase 3 trial, a two-dose Ebola vaccine regimen in healthy pregnant women in Rwanda was found to be safe and immunogenic in women and offspring through passive transfer.

www.nature.com

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Reposted by Mary Prahl, MD

BK. Titanji @boghuma.bsky.social · Aug 29

We should be able to agree that funding research for pediatric cancer should be prioritized and expanded. Not canceled. Clinical trials that can be the last hope for kids with cancer stopping recruitment due to funding loss is heartbreaking 💔
www.nytimes.com/2025/08/28/w...

Pediatric Brain Cancer Group to Lose Federal Funding

www.nytimes.com

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Reposted by Mary Prahl, MD

Gladstone Institutes @gladstoneinst.bsky.social · Jul 31

🚨 NEW PUBLICATION 🚨 "Pregnancy and lactation induce distinct immune responses to #COVID19 booster vaccination and SARS-CoV-2 breakthrough infection" from the Roan Lab in
@jci-insight.bsky.social

JCI Insight - Pregnancy and lactation induce distinct immune responses to COVID-19 booster vaccination and SARS-CoV-2 breakthrough infection

insight.jci.org

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Reposted by Mary Prahl, MD

Gladstone Institutes @gladstoneinst.bsky.social · Jul 31

A team of scientists, led by Nadia Roan, found that pregnant and lactating women have strong immune defenses to COVID-19, and identified key benefits that could guide future vaccine design.

Discovery Spotlight | Pregnancy, Lactation Shape Immune Response to COVID-19 Vaccine and Infection

YouTube video by Gladstone Institutes

youtube.com

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Reposted by Mary Prahl, MD

Gladstone Institutes @gladstoneinst.bsky.social · Jul 23

Study finds strong immune defenses in pregnant and lactating women, with key benefits that could guide future vaccine design.

Pregnancy, Lactation Shape Immune Response to COVID-19 Vaccine and Infection

Study finds strong immune defenses in pregnant and lactating women, with key benefits that could guide future vaccine design.

gladstone.org

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Reposted by Mary Prahl, MD

Gladstone Institutes @gladstoneinst.bsky.social · Jul 23

🚨 NEW PUBLICATION 🚨 "Pregnancy and lactation induce distinct immune responses to COVID-19 booster vaccination and SARS-CoV-2 breakthrough infection" from the Roan Lab in @jci-insight.bsky.social

JCI Insight - Pregnancy and lactation induce distinct immune responses to COVID-19 booster vaccination and SARS-CoV-2 breakthrough infection

insight.jci.org

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Reposted by Mary Prahl, MD

BK. Titanji @boghuma.bsky.social · Jul 22

On a day that the congress has decided to go on an early recess and take 6 weeks of paid leave it is important to remember that in the U.S there is no federal law that guarantees paid maternity leave or family leave.
Just something to think about in case you need more things to think about today.

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Mary Prahl, MD @mkprahl.bsky.social · Jul 22

Led by Kailin Yin and Lin Li. Many thanks to the incredible participants and our awesome COVIPAL team @gawlab.bsky.social and Roan lab collaborators. @ucsfchildrens.bsky.social @ucsfhealth.bsky.social @gladstoneinst.bsky.social

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Mary Prahl, MD @mkprahl.bsky.social · Jul 22

Another interesting finding was that T cells in the blood of lactating individuals were less activated after vaccination. Which may be related to differential trafficking to the mammary glands for T cells into breastmilk. More details here by Julie Langelier gladstone.org/news/pregnan...

Pregnancy, Lactation Shape Immune Response to COVID-19 Vaccine and Infection

Study finds strong immune defenses in pregnant and lactating women, with key benefits that could guide future vaccine design.

gladstone.org

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Mary Prahl, MD @mkprahl.bsky.social · Jul 22

after COVID-19 vaccine and infection. Some major findings include that COVID-19 vaccination in pregnancy elicited just as strong as an immune response as non-pregnant women. We found that vaccination in pregnancy had some unique immunologic benefits including increased "stem-like" T cells (3/n)

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Mary Prahl, MD @mkprahl.bsky.social · Jul 22

Many pregnant front-line workers had some of the same concerns. We developed the COVIPAL study to evaluate the immune responses to COVID-19 vaccination in pregnancy and lactation. Working with our close collaborators in the Roan lab at @gladstoneinst.bsky.social, we did deep immune profiling (2/n)

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Mary Prahl, MD @mkprahl.bsky.social · Jul 22

Happy to share our new work @jci-insight.bsky.social insight.jci.org/articles/vie... When I was pregnant in Dec 2020, one of the many things that concerned me was if the COVID-19 vaccine would protect me as well as non-pregnant people, as I knew the high risk of COVID-19 infection in pregnancy (1/n)

insight.jci.org

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Reposted by Mary Prahl, MD

IDSA @idsainfo.bsky.social · Jul 7

🚨BREAKING: IDSA, along with AAP, APHA, ACP and others, has filed a lawsuit against HHS/Secretary Kennedy to stop unlawful changes to vaccine policy and defend public health.

We refuse to stand by while America’s public health safeguards are torn apart. bit.ly/4lm7UkW

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Reposted by Mary Prahl, MD

Apoorva Mandavilli @apoorvanyt.bsky.social · Jul 7

BREAKING: Six leading medical organizations filed a lawsuit on Monday against Robert F. Kennedy Jr., the health secretary, and the health dept, charging that recent decisions limiting access to vaccines were unscientific and harmful to the public.
(Gift link)

www.nytimes.com/2025/07/07/h...

Medical Societies Sue Kennedy and H.H.S. Over Vaccine Advice

www.nytimes.com

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Reposted by Mary Prahl, MD

The American Academy of Pediatrics @ameracadpeds.bsky.social · Jun 25

Hepatitis B can be passed from parent to baby at birth - and when that happens, the consequences can be deadly. It is unscientific and dangerous to intentionally ignore the success of U.S. vaccination programs or argue that the U.S. should not vaccinate babies for hepatitis B at birth.

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Reposted by Mary Prahl, MD

Edward Nirenberg @enirenberg.bsky.social · Jun 25

We now have presentations on COVID-19 vaccine effectiveness:
www.cdc.gov/acip/downloa...

These presentations can become very confusing so I need to explain a bit about them:

www.cdc.gov

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Reposted by Mary Prahl, MD

Edward Nirenberg @enirenberg.bsky.social · Jun 13

In case you needed another reason to hate Epstein-Barr virus- it looks like it might cause primary sclerosing cholangitis:

www.nature.com/articles/s41...

T and B cell responses against Epstein–Barr virus in primary sclerosing cholangitis - Nature Medicine

Interrogation of electronic health records and the B and T cell repertoires of people with PSC shows a link between Epstein–Barr virus and primary sclerosing cholangitis, an incurable autoimmune liver...

www.nature.com

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Reposted by Mary Prahl, MD

Devan Jaganath, MD MPH @djaganath.bsky.social · Jun 6

New Publication: We conducted a multi-country prospective comparison of 3 methods for stool processing for Xpert Ultra testing for childhood TB, and found they performed similarly and were usable and acceptable by lab workers: academic.oup.com/cid/advance-.... @cidjournal.bsky.social #tbsky #idsky

Stool processing methods for Xpert Ultra testing in childhood tuberculosis: A prospective, multi-country accuracy study

AbstractBackground. Centrifuge-free processing methods support stool Xpert Ultra testing for childhood tuberculosis (TB), but there are limited data on the

academic.oup.com

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Reposted by Mary Prahl, MD

KFF Health News @kffhealthnews.org · Jun 2

You’re pregnant, healthy, and hearing mixed messages: RFK Jr. says you don’t need the covid vaccine, but experts at the CDC still put you in a high-risk group of people who ought to receive boosters.

Here's what the science says. 👇
kffhealthnews.org/news/article...

RFK Jr. Says Healthy Pregnant Women Don’t Need Covid Boosters. What the Science Says. - KFF Health News

Despite opposition by the leader of the Department of Health and Human Services, existing evidence on the safety and efficacy of getting a covid vaccine during pregnancy all points the same way: The s...

kffhealthnews.org

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Reposted by Mary Prahl, MD

Elizabeth Warren @warren.senate.gov · May 27

When Americans raised concerns about RFK Jr.'s anti-vaccine views, he said he was "not gonna take away vaccines from anybody."

But now he's taking them away from millions of mommas and babies.

Vaccine recommendations should be based on science, not RFK Jr.'s political agenda.

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Reposted by Mary Prahl, MD

ACOG @acog.org · May 27

ACOG is deeply disappointed by HHS’s move to drop COVID-19 vaccine recommendations in pregnancy. The science is clear: COVID-19 remains dangerous in pregnancy and vaccination protects both patients and newborns. The vaccine is safe and protects families. Read our full statement: buff.ly/OGue7sO

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Reposted by Mary Prahl, MD

PIDS @pidsociety.bsky.social · May 27

News on CDC's COVID-19 vaccine recommendation removed for pregnant women and children. #IDSky
www.nbcnews.com/health/healt...

CDC ends Covid vaccine recommendation for healthy kids and pregnant women

Health and Human Services Secretary Robert F. Kennedy Jr. — a Covid vaccine critic — made the announcement on X.

www.nbcnews.com

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Reposted by Mary Prahl, MD

Alt CDC (they/them) @altcdc.altgov.info · May 27

Pregnancy is a major risk factor for severe COVID-19 outcomes (read: death). GOP, if you want women to have more babies, how about making it easier for women to do that without dying?

RFK Jr. says Covid-19 shot will no longer be recommended for healthy children and pregnant women | CNN

US Health and Human Services Robert F. Kennedy Jr. announced Tuesday said the Covid-19 vaccine will no longer be among the recommended vaccines for pregnant women and healthy children on the US Center...

edition.cnn.com

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