Gladstone Institutes
@gladstoneinst.bsky.social
To drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and diverse environment.
Congenital heart defects affect 1 in 100 babies, yet the cause remains unknown in more than half of all cases. In this short, Gladstone scientist @j-muncie-vasic.bsky.social explains why early missteps in heart development can have lasting consequences.
Uncovering the Early Causes of Congenital Heart Defects
YouTube video by Gladstone Institutes
youtube.com
February 12, 2026 at 9:49 PM
Congenital heart defects affect 1 in 100 babies, yet the cause remains unknown in more than half of all cases. In this short, Gladstone scientist @j-muncie-vasic.bsky.social explains why early missteps in heart development can have lasting consequences.
Reposted by Gladstone Institutes
I am excited to share our latest preprint showing that systemic hypoxia suppresses solid tumor growth: www.biorxiv.org/content/10.6...
This has been a tremendous collaborative effort in the labs of Isha Jain @ishahjain.bsky.social and Hani Goodarzi @genophoria.bsky.social.
This has been a tremendous collaborative effort in the labs of Isha Jain @ishahjain.bsky.social and Hani Goodarzi @genophoria.bsky.social.
www.biorxiv.org
February 10, 2026 at 8:58 PM
I am excited to share our latest preprint showing that systemic hypoxia suppresses solid tumor growth: www.biorxiv.org/content/10.6...
This has been a tremendous collaborative effort in the labs of Isha Jain @ishahjain.bsky.social and Hani Goodarzi @genophoria.bsky.social.
This has been a tremendous collaborative effort in the labs of Isha Jain @ishahjain.bsky.social and Hani Goodarzi @genophoria.bsky.social.
Steve Finkbeiner comments on new restrictions that many scientists believe will slow research on fetal development and stem-cell biology.
NIH ends support for most human fetal-tissue research – dismaying some scientists
The US biomedical funding agency also hints at future restrictions on research involving human embryonic stem cells.
go.nature.com
February 11, 2026 at 5:48 PM
Steve Finkbeiner comments on new restrictions that many scientists believe will slow research on fetal development and stem-cell biology.
This week is #CongenitalHeartDefectsAwarenessWeek.
Nearly 1 in 100 babies is born with a hole in their heart. In a new study, Gladstone scientists uncovered a hidden “navigation system” that guides early heart development—and how its disruption can lead to heart defects.
Nearly 1 in 100 babies is born with a hole in their heart. In a new study, Gladstone scientists uncovered a hidden “navigation system” that guides early heart development—and how its disruption can lead to heart defects.
Discovery Spotlight | Disrupted Boundary Between Cell Types Linked to Common Heart Defects
YouTube video by Gladstone Institutes
youtube.com
February 10, 2026 at 3:15 PM
This week is #CongenitalHeartDefectsAwarenessWeek.
Nearly 1 in 100 babies is born with a hole in their heart. In a new study, Gladstone scientists uncovered a hidden “navigation system” that guides early heart development—and how its disruption can lead to heart defects.
Nearly 1 in 100 babies is born with a hole in their heart. In a new study, Gladstone scientists uncovered a hidden “navigation system” that guides early heart development—and how its disruption can lead to heart defects.
Reposted by Gladstone Institutes
another outstanding @gladstoneinst.bsky.social hike, this time Tilden Park in Berkeley.
February 8, 2026 at 9:23 PM
another outstanding @gladstoneinst.bsky.social hike, this time Tilden Park in Berkeley.
Steve Finkbeiner is presenting his work today as an SLAS2026 Innovation Award finalist!
Learn more: https://bit.ly/3NgUPgt
Learn more: https://bit.ly/3NgUPgt
February 9, 2026 at 3:07 PM
Steve Finkbeiner is presenting his work today as an SLAS2026 Innovation Award finalist!
Learn more: https://bit.ly/3NgUPgt
Learn more: https://bit.ly/3NgUPgt
Check out this feature in @dev-journal.bsky.social featuring Irfan Kathiriya and Benoit Bruneau, who talk about the journey behind their recent paper, what drew them to heart development research, and collaborations that shape their work.
@benoitbruneau.bsky.social
@irfankathiriya.bsky.social
@benoitbruneau.bsky.social
@irfankathiriya.bsky.social
The people behind the papers – Irfan Kathiriya and Benoit Bruneau
The heart's atria and ventricles have different functions and developmental origins, and common cardiac defects have specific effects on each chamber. However, the gene regulatory networks (GRN) that ...
bit.ly
February 7, 2026 at 8:06 PM
Check out this feature in @dev-journal.bsky.social featuring Irfan Kathiriya and Benoit Bruneau, who talk about the journey behind their recent paper, what drew them to heart development research, and collaborations that shape their work.
@benoitbruneau.bsky.social
@irfankathiriya.bsky.social
@benoitbruneau.bsky.social
@irfankathiriya.bsky.social
Looking for a new job? Here are some open roles at Gladstone. 🧵
Gladstone Infectious Disease Institute/UCSF Department of Bioengineering and Therapeutics Sciences - Faculty Position: bit.ly/4ajt52G
Gladstone Infectious Disease Institute/UCSF Department of Bioengineering and Therapeutics Sciences - Faculty Position: bit.ly/4ajt52G
February 6, 2026 at 2:23 PM
Looking for a new job? Here are some open roles at Gladstone. 🧵
Gladstone Infectious Disease Institute/UCSF Department of Bioengineering and Therapeutics Sciences - Faculty Position: bit.ly/4ajt52G
Gladstone Infectious Disease Institute/UCSF Department of Bioengineering and Therapeutics Sciences - Faculty Position: bit.ly/4ajt52G
Applications for PUMAS are now open! PUMAS is designed to support and mentor community college students, providing them with hands-on research experience and a pathway into the sciences.
Past interns share their experiences, and how the program impacted their lives.
https://bit.ly/4izhKyd
Past interns share their experiences, and how the program impacted their lives.
https://bit.ly/4izhKyd
YouTube
Share your videos with friends, family, and the world
bit.ly
February 5, 2026 at 9:51 PM
Applications for PUMAS are now open! PUMAS is designed to support and mentor community college students, providing them with hands-on research experience and a pathway into the sciences.
Past interns share their experiences, and how the program impacted their lives.
https://bit.ly/4izhKyd
Past interns share their experiences, and how the program impacted their lives.
https://bit.ly/4izhKyd
Gladstone Investigator Karin Pelka shares what scientists are doing to expand the benefits of immunotherapy to currently unresponsive solid tumors.
#WorldCancerDay
#WorldCancerDay
Ask a Scientist: When Will Immunotherapy Work on Common Cancers?
For Cancer Immunotherapy Month, Karin Pelka answers questions about how immunotherapy can treat patients with solid tumors and the challenges that scientists are working to overcome.
bit.ly
February 4, 2026 at 9:09 PM
Gladstone Investigator Karin Pelka shares what scientists are doing to expand the benefits of immunotherapy to currently unresponsive solid tumors.
#WorldCancerDay
#WorldCancerDay
The State of Gladstone is where our community comes together to reflect, connect, and look ahead.
Here are some highlights from this year’s gathering.
Here are some highlights from this year’s gathering.
February 3, 2026 at 6:10 PM
The State of Gladstone is where our community comes together to reflect, connect, and look ahead.
Here are some highlights from this year’s gathering.
Here are some highlights from this year’s gathering.
Every year, nearly 1 in 100 babies are born with a hole in their heart. These heart defects often result in a lifetime of invasive surgeries, medications, and constant monitoring.
February 2, 2026 at 8:56 PM
Every year, nearly 1 in 100 babies are born with a hole in their heart. These heart defects often result in a lifetime of invasive surgeries, medications, and constant monitoring.
Reposted by Gladstone Institutes
Getting to the heart of atrial cardiomyocyte identity
This Research Highlight showcases work by Irfan Kathiriya @irfankathiriya.bsky.social, Benoit Bruneau @benoitbruneau.bsky.social and colleagues at @gladstoneinst.bsky.social & @ucsfanesthesia.bsky.social
journals.biologists.com/dev/article/...
This Research Highlight showcases work by Irfan Kathiriya @irfankathiriya.bsky.social, Benoit Bruneau @benoitbruneau.bsky.social and colleagues at @gladstoneinst.bsky.social & @ucsfanesthesia.bsky.social
journals.biologists.com/dev/article/...
January 30, 2026 at 11:06 PM
Getting to the heart of atrial cardiomyocyte identity
This Research Highlight showcases work by Irfan Kathiriya @irfankathiriya.bsky.social, Benoit Bruneau @benoitbruneau.bsky.social and colleagues at @gladstoneinst.bsky.social & @ucsfanesthesia.bsky.social
journals.biologists.com/dev/article/...
This Research Highlight showcases work by Irfan Kathiriya @irfankathiriya.bsky.social, Benoit Bruneau @benoitbruneau.bsky.social and colleagues at @gladstoneinst.bsky.social & @ucsfanesthesia.bsky.social
journals.biologists.com/dev/article/...
Katie Pollard weighs in on the advancement of applying AI to the human genome with Google DeepMind’s AlphaGenome.
Researchers Are Using A.I. to Decode the Human Genome
www.nytimes.com
February 1, 2026 at 6:24 PM
Katie Pollard weighs in on the advancement of applying AI to the human genome with Google DeepMind’s AlphaGenome.
Postdoc Shyam Jinagal breaks down his research on cardiovascular disease.
January 30, 2026 at 10:06 PM
Postdoc Shyam Jinagal breaks down his research on cardiovascular disease.
In our latest newsletter, scientists found a gene that guides proper heart development, recipients of Gladstone’s Outstanding Mentoring Award share their approaches to mentorship, and Yadong Huang has a new leadership role.
mailchi.mp/gladstone/ce...
mailchi.mp/gladstone/ce...
Cell Signals〡New Roadmap for Preventing Congenital Heart Disease
mailchi.mp
January 29, 2026 at 10:15 PM
In our latest newsletter, scientists found a gene that guides proper heart development, recipients of Gladstone’s Outstanding Mentoring Award share their approaches to mentorship, and Yadong Huang has a new leadership role.
mailchi.mp/gladstone/ce...
mailchi.mp/gladstone/ce...
Reposted by Gladstone Institutes
1 in 100 babies are born with holes in the wall between their heart chambers. @gladstoneinst.bsky.social scientists led by @benoitbruneau.bsky.social have uncovered why: a boundary of cells gets disrupted, causing left and right heart cells to mix. gladstone.org/news/disrupt...
Disrupted Boundary Between Cell Types Linked to Common Heart Defects
Gladstone scientists identified a cellular boundary that guides heart development and revealed how disrupting it can lead to holes in the heart’s wall.
gladstone.org
January 29, 2026 at 6:11 PM
1 in 100 babies are born with holes in the wall between their heart chambers. @gladstoneinst.bsky.social scientists led by @benoitbruneau.bsky.social have uncovered why: a boundary of cells gets disrupted, causing left and right heart cells to mix. gladstone.org/news/disrupt...
Three recipients of Gladstone’s Outstanding Mentoring Award share their personal approaches to mentorship and reflect how this passion has shaped their own growth as leaders.
Voices of Outstanding Mentorship
Three recipients of Gladstone's Outstanding Mentoring Award share their personal approaches to mentorship and reflect how this passion has shaped their own growth as leaders.
gladstone.org
January 28, 2026 at 5:53 PM
Three recipients of Gladstone’s Outstanding Mentoring Award share their personal approaches to mentorship and reflect how this passion has shaped their own growth as leaders.
Congratulations to Yadong Huang, who has been appointed Associate Director of the Gladstone Institute of Neurological Disease.
Check out this thread to learn more about his career and impact at Gladstone.
Check out this thread to learn more about his career and impact at Gladstone.
January 27, 2026 at 8:06 PM
Congratulations to Yadong Huang, who has been appointed Associate Director of the Gladstone Institute of Neurological Disease.
Check out this thread to learn more about his career and impact at Gladstone.
Check out this thread to learn more about his career and impact at Gladstone.
Steve Finkbeiner, who has been selected as an #SLAS2026 Innovation Award finalist, will soon be presenting his work at the SLAS2026 International Conference & Exhibition in Boston.
Learn more: https://bit.ly/3NgUPgt
Learn more: https://bit.ly/3NgUPgt
January 27, 2026 at 6:09 PM
Steve Finkbeiner, who has been selected as an #SLAS2026 Innovation Award finalist, will soon be presenting his work at the SLAS2026 International Conference & Exhibition in Boston.
Learn more: https://bit.ly/3NgUPgt
Learn more: https://bit.ly/3NgUPgt
🧫 Want to explore what it’s like to be a scientist? PUMAS offers mentorship, workshops, and hands-on research experience. Don’t miss out! 🚨 ✨
Learn more about the program and how to apply 👉 https://bit.ly/2UVIaST
Learn more about the program and how to apply 👉 https://bit.ly/2UVIaST
January 26, 2026 at 9:30 PM
🧫 Want to explore what it’s like to be a scientist? PUMAS offers mentorship, workshops, and hands-on research experience. Don’t miss out! 🚨 ✨
Learn more about the program and how to apply 👉 https://bit.ly/2UVIaST
Learn more about the program and how to apply 👉 https://bit.ly/2UVIaST
Gladstone scientists identified a cellular boundary that guides heart development and revealed how disrupting it can lead to holes in the heart’s wall.
Disrupted Boundary Between Cell Types Linked to Common Heart Defects
Gladstone scientists identified a cellular boundary that guides heart development and revealed how disrupting it can lead to holes in the heart's wall.
bit.ly
January 24, 2026 at 7:47 PM
Gladstone scientists identified a cellular boundary that guides heart development and revealed how disrupting it can lead to holes in the heart’s wall.
Meet Shyam Jinagal, a postdoc in the lab of Deepak Srivastava. Jinagal explores how genetics, aging, and regeneration shape the heart—and how those insights could one day restore heart function after injury.
Read the full interview with Jinagal 👇 👇 👇
https://bit.ly/4k4PdSY
Read the full interview with Jinagal 👇 👇 👇
https://bit.ly/4k4PdSY
Meet Gladstone: Shyam Jinagal
Postdoctoral researcher Shyam Jinagal studies how genetic and age-related changes contribute to aortic valve disease and the loss of the adult heart's regenerative capacity, with the goal of restoring heart function after injury.
bit.ly
January 23, 2026 at 9:52 PM
Meet Shyam Jinagal, a postdoc in the lab of Deepak Srivastava. Jinagal explores how genetics, aging, and regeneration shape the heart—and how those insights could one day restore heart function after injury.
Read the full interview with Jinagal 👇 👇 👇
https://bit.ly/4k4PdSY
Read the full interview with Jinagal 👇 👇 👇
https://bit.ly/4k4PdSY
🚨NEW PUBLICATION 🚨 "A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects"
@irfankathiriya.bsky.social
@ucsfanesthesia.bsky.social
@benoitbruneau.bsky.social
@natcardiovascres.nature.com
https://go.nature.com/49X4a4J
@irfankathiriya.bsky.social
@ucsfanesthesia.bsky.social
@benoitbruneau.bsky.social
@natcardiovascres.nature.com
https://go.nature.com/49X4a4J
A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects - Nature Cardiovascular Research
Kathiriya et al. identify a cardiac progenitor lineage with expression of Tbx5 and anterior heart field-specific expression of Mef2c that bisects the intraventricular septum during development and sho...
www.nature.com
January 23, 2026 at 8:45 PM
🚨NEW PUBLICATION 🚨 "A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects"
@irfankathiriya.bsky.social
@ucsfanesthesia.bsky.social
@benoitbruneau.bsky.social
@natcardiovascres.nature.com
https://go.nature.com/49X4a4J
@irfankathiriya.bsky.social
@ucsfanesthesia.bsky.social
@benoitbruneau.bsky.social
@natcardiovascres.nature.com
https://go.nature.com/49X4a4J
Looking for a new position? Gladstone is hiring.
💻 Bioinformatics Scientist: https://bit.ly/4sUA3U4
🥼 Research Associate II- Huang Lab: https://bit.ly/4a5YGWt
👩💼 Accounting Manager: https://bit.ly/4qOL2gc
💻 Bioinformatics Scientist: https://bit.ly/4sUA3U4
🥼 Research Associate II- Huang Lab: https://bit.ly/4a5YGWt
👩💼 Accounting Manager: https://bit.ly/4qOL2gc
January 22, 2026 at 10:12 PM
Looking for a new position? Gladstone is hiring.
💻 Bioinformatics Scientist: https://bit.ly/4sUA3U4
🥼 Research Associate II- Huang Lab: https://bit.ly/4a5YGWt
👩💼 Accounting Manager: https://bit.ly/4qOL2gc
💻 Bioinformatics Scientist: https://bit.ly/4sUA3U4
🥼 Research Associate II- Huang Lab: https://bit.ly/4a5YGWt
👩💼 Accounting Manager: https://bit.ly/4qOL2gc