@moorjanipriya.bsky.social
Pinned
Revisiting the Evolution of Lactase Persistence: Insights from South Asian Genomes
Lactase persistence (LP), the ability to digest lactose from milk into adulthood, is a classic example of natural selection in humans. Multiple mutations upstream of the LCT gene are associated with L...
www.biorxiv.org
Exciting new study led by @ekerdoncuff.bsky.social and @meaghanmarohn.bsky.social on the evolution of Lactase Persistence in South Asia.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A
Insertion of an invading retrovirus regulates a novel color trait in swordtail fish
For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...
shorturl.at
November 12, 2025 at 8:34 PM
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A
Reposted
Exited to have such a great set of speakers for Ancient genomes: perspectives on human biology and medicine
The program is now online and registration is still open!
registrations.hg3conferences.co.uk/hg3/frontend...
The program is now online and registration is still open!
registrations.hg3conferences.co.uk/hg3/frontend...
August 28, 2025 at 9:05 AM
Exited to have such a great set of speakers for Ancient genomes: perspectives on human biology and medicine
The program is now online and registration is still open!
registrations.hg3conferences.co.uk/hg3/frontend...
The program is now online and registration is still open!
registrations.hg3conferences.co.uk/hg3/frontend...
Exciting new study led by @ekerdoncuff.bsky.social and @meaghanmarohn.bsky.social on the evolution of Lactase Persistence in South Asia.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Revisiting the Evolution of Lactase Persistence: Insights from South Asian Genomes
Lactase persistence (LP), the ability to digest lactose from milk into adulthood, is a classic example of natural selection in humans. Multiple mutations upstream of the LCT gene are associated with L...
www.biorxiv.org
November 7, 2025 at 2:33 PM
Exciting new study led by @ekerdoncuff.bsky.social and @meaghanmarohn.bsky.social on the evolution of Lactase Persistence in South Asia.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Save the date! ProbGen 2026 will be hosted at UC Berkeley, March 25 to March 28, 2026. Featuring keynote speakers @jkpritch.bsky.social and Sally Otto. More details soon...
May 7, 2025 at 3:27 PM
Save the date! ProbGen 2026 will be hosted at UC Berkeley, March 25 to March 28, 2026. Featuring keynote speakers @jkpritch.bsky.social and Sally Otto. More details soon...
Reposted
@leonardoiasi.bsky.social
High sharing of N. segments between populations except the earliest Out of Africa populations. Duration of gene flow inferred. Evidence of rapid - and + selection.
Deserts of N. ancestry rapidly formed after the introgression. 🏜️
#HumanEvo25
High sharing of N. segments between populations except the earliest Out of Africa populations. Duration of gene flow inferred. Evidence of rapid - and + selection.
Deserts of N. ancestry rapidly formed after the introgression. 🏜️
#HumanEvo25
April 28, 2025 at 4:42 PM
@leonardoiasi.bsky.social
High sharing of N. segments between populations except the earliest Out of Africa populations. Duration of gene flow inferred. Evidence of rapid - and + selection.
Deserts of N. ancestry rapidly formed after the introgression. 🏜️
#HumanEvo25
High sharing of N. segments between populations except the earliest Out of Africa populations. Duration of gene flow inferred. Evidence of rapid - and + selection.
Deserts of N. ancestry rapidly formed after the introgression. 🏜️
#HumanEvo25
Reposted
Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
April 7, 2025 at 2:01 PM
Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
Reposted
Posting on behalf of Shamil Sunyaev: Eimear(Vice Chair) and I (Chair) are organizing the 2025 Gordon Research Conference (GRC) on Human Genetics and Genomics, which will be held on July 6-11, 2025 in beautiful University of Southern Maine, Portland, Maine.
2025 Human Genetics and Genomics Conference GRC
The 2025 Gordon Research Conference on Human Genetics and Genomics will be held in Portland, Maine. Apply today to reserve your spot.
www.grc.org
April 24, 2025 at 2:31 PM
Posting on behalf of Shamil Sunyaev: Eimear(Vice Chair) and I (Chair) are organizing the 2025 Gordon Research Conference (GRC) on Human Genetics and Genomics, which will be held on July 6-11, 2025 in beautiful University of Southern Maine, Portland, Maine.
Reposted
Had the opportunity to present my work on Lactase Persistence in South Asia, in collaboration with Meaghan Maroon, at #probgen25! Excited to share our findings with this amazing community!
March 7, 2025 at 12:39 PM
Had the opportunity to present my work on Lactase Persistence in South Asia, in collaboration with Meaghan Maroon, at #probgen25! Excited to share our findings with this amazing community!
Reposted
From the editors of @asm.org journals, a call to action!
Below we discuss the U.S. scientific research enterprise and provide evidence and arguments we hope the ASM community can use to advocate for science.
journals.asm.org/doi/10.1128/...
Below we discuss the U.S. scientific research enterprise and provide evidence and arguments we hope the ASM community can use to advocate for science.
journals.asm.org/doi/10.1128/...
A call for the United States to continue investing in science | mBio
The U.S. life science research mission is critical not only to human health and understanding
the natural world but also to agriculture and food production, technological innovations,
socioeconomic pr...
journals.asm.org
February 27, 2025 at 7:05 PM
From the editors of @asm.org journals, a call to action!
Below we discuss the U.S. scientific research enterprise and provide evidence and arguments we hope the ASM community can use to advocate for science.
journals.asm.org/doi/10.1128/...
Below we discuss the U.S. scientific research enterprise and provide evidence and arguments we hope the ASM community can use to advocate for science.
journals.asm.org/doi/10.1128/...
Reposted
Despite the chaos in the world, I am excited to share our new paper just out in Mol Ecol. We studied the interplay between the effects of host plant variation and viral infection on physiological responses and gene expression in Melissa blue butterflies.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
High Quality Diet Enhances Immune Response and Affects Gene Expression During Viral Infection in an Insect Herbivore
Herbivorous insects tolerate chemical and metabolic variation in their host plant diet by modulating physiological traits. Insect immune response is one such trait that plays a crucial role in mainta....
onlinelibrary.wiley.com
February 26, 2025 at 7:07 PM
Despite the chaos in the world, I am excited to share our new paper just out in Mol Ecol. We studied the interplay between the effects of host plant variation and viral infection on physiological responses and gene expression in Melissa blue butterflies.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Reposted
Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives.
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
Trump 2.0: an assault on science anywhere is an assault on science everywhere
US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.
www.nature.com
February 25, 2025 at 7:48 PM
Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives.
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
Reposted
CT friends! We are standing up for Science on March 7th in Hartford!
Stay tuned for details —
@centromellone.bsky.social
@davidbreslowlab.bsky.social
@gregggonsalves.bsky.social @luskinglab.bsky.social
Stay tuned for details —
@centromellone.bsky.social
@davidbreslowlab.bsky.social
@gregggonsalves.bsky.social @luskinglab.bsky.social
February 23, 2025 at 2:58 AM
CT friends! We are standing up for Science on March 7th in Hartford!
Stay tuned for details —
@centromellone.bsky.social
@davidbreslowlab.bsky.social
@gregggonsalves.bsky.social @luskinglab.bsky.social
Stay tuned for details —
@centromellone.bsky.social
@davidbreslowlab.bsky.social
@gregggonsalves.bsky.social @luskinglab.bsky.social
Reposted
Happy 37th birthday to the LTEE!
the-ltee.org/history/
the-ltee.org/history/
History – The Long-Term Evolution Experiment
the-ltee.org
February 24, 2025 at 3:39 PM
Happy 37th birthday to the LTEE!
the-ltee.org/history/
the-ltee.org/history/
Reposted
I'm very proud of my organisation for showing clear leadership during these challenging days. "PLOS will always anchor our decisions in our values and our principles. And we will continue to speak up vocally for open, independent science."
PLOS has issued a statement on recent US Executive Orders and scientific integrity.
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog
Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…
plos.io
February 21, 2025 at 3:53 PM
I'm very proud of my organisation for showing clear leadership during these challenging days. "PLOS will always anchor our decisions in our values and our principles. And we will continue to speak up vocally for open, independent science."
Reposted
Reminder to call House Energy & Commerce Committee chaired by KY Rep. Brett Guthrie (202-225-3641) and Senate HELP Committee chaired by LA Sen. Bill Cassidy (202-224-6770). Call Guthrie’s regular office too (202-225-3501). Register your concern regarding:
1. Help: NIH study sections and council meetings not already published in the Federal Register as of Jan. 21 have not been allowed to meet (thetransmitter.org/funding/fede...). This appears to be an 'end run' around a recent injunction and came from HHS officials. You can help (see below):
Federal Register hold makes ‘end run’ around court pause on NIH funding freeze
NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...
thetransmitter.org
February 20, 2025 at 4:53 PM
Reminder to call House Energy & Commerce Committee chaired by KY Rep. Brett Guthrie (202-225-3641) and Senate HELP Committee chaired by LA Sen. Bill Cassidy (202-224-6770). Call Guthrie’s regular office too (202-225-3501). Register your concern regarding:
Reposted
To all people who value science as a source of truth, cures for diseases, and hope for our climate and future, here are 2 hard truths:
1) our current research ecosystem is already strained and very fragile;
2) If it gets broken it will take a generation or longer to repair.
Here’s why:
1/n
1) our current research ecosystem is already strained and very fragile;
2) If it gets broken it will take a generation or longer to repair.
Here’s why:
1/n
February 20, 2025 at 7:04 PM
To all people who value science as a source of truth, cures for diseases, and hope for our climate and future, here are 2 hard truths:
1) our current research ecosystem is already strained and very fragile;
2) If it gets broken it will take a generation or longer to repair.
Here’s why:
1/n
1) our current research ecosystem is already strained and very fragile;
2) If it gets broken it will take a generation or longer to repair.
Here’s why:
1/n
Reposted
Excellent story fleshing out hie midern humans migrated far and wide in Europe for the beginning, and when they made it with Neanderthsls: www.science.org/content/arti...
Mystery woman’s DNA reveals close family ties between Europe’s earliest people
Pair of studies shines light on how modern humans and Neanderthals settled the continent together
www.science.org
December 13, 2024 at 2:24 AM
Excellent story fleshing out hie midern humans migrated far and wide in Europe for the beginning, and when they made it with Neanderthsls: www.science.org/content/arti...
Reposted
My summary of the new aDNA papers on Neanderthal interbreeding
December 12, 2024 at 7:01 PM
My summary of the new aDNA papers on Neanderthal interbreeding
Reposted
Enthralled to see our work published in Science. This wouldn’t have been possible without the wonderful contributions of the team comprising @moorjanipriya.bsky.social @leonardoiasi.bsky.social @benmpeter.bsky.social @lauritsskov.bsky.social @matejahajdi.bsky.social and Alba!
Out today in @sciencemagazine, we've journeyed into our shared history with Neandertals by analyzing over 300 present-day and ancient modern humans, including 59 individuals who lived between 2,000 and 45,000 years ago.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans
Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments in more than 300 genomes spanning the past 50,000 year...
www.science.org
December 12, 2024 at 10:28 PM
Enthralled to see our work published in Science. This wouldn’t have been possible without the wonderful contributions of the team comprising @moorjanipriya.bsky.social @leonardoiasi.bsky.social @benmpeter.bsky.social @lauritsskov.bsky.social @matejahajdi.bsky.social and Alba!
Reposted
More on the timing of neanderthal/sapiens admixture
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Neanderthals and humans interbred more recently than scientists thought
Two teams using different methods both conclude that humans and Neanderthals had children together starting roughly 50,000 years ago.
www.nature.com
December 12, 2024 at 8:23 PM
More on the timing of neanderthal/sapiens admixture
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted
The first paper, lead by @arevsumer.bsky.social, Kay Prüfer and Johannes Krause, describes some amazing new genomes from Ranis and Zlaty Kun. See Arev’s write-up here:
I am very happy to share our new paper on the genetics of some of the first modern humans who ever lived in Europe! We sequenced nuclear DNA from 13 specimens from Ranis in Germany, and found that they belonged to at least 6 individuals. www.nature.com/articles/s41... (1/n)
Earliest modern human genomes constrain timing of Neanderthal admixture - Nature
Nature - Earliest modern human genomes constrain timing of Neanderthal admixture
www.nature.com
December 12, 2024 at 7:28 PM
The first paper, lead by @arevsumer.bsky.social, Kay Prüfer and Johannes Krause, describes some amazing new genomes from Ranis and Zlaty Kun. See Arev’s write-up here:
Reposted
The second paper is a systematic survey of Neandertal ancestry through time; a joint effort with @moorjanipriya.bsky.social ya.bsky.social’s lab at UC Berkeley, co-led by @leonardoiasi.bsky.social and Manjusha Chintalapati. Leo has a great summary of our main findings here:
December 12, 2024 at 7:47 PM
The second paper is a systematic survey of Neandertal ancestry through time; a joint effort with @moorjanipriya.bsky.social ya.bsky.social’s lab at UC Berkeley, co-led by @leonardoiasi.bsky.social and Manjusha Chintalapati. Leo has a great summary of our main findings here:
Very excited to see our study published today, joint effort with @benmpeter.bsky.social group, co-led by @leonardoiasi.bsky.social & Manjusha Chintalapati. Excitedly, @arevsumer.bsky.social et al. in Nature today show similar timeline of N gene flow. Details👇
Out today in @sciencemagazine, we've journeyed into our shared history with Neandertals by analyzing over 300 present-day and ancient modern humans, including 59 individuals who lived between 2,000 and 45,000 years ago.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans
Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments in more than 300 genomes spanning the past 50,000 year...
www.science.org
December 12, 2024 at 7:57 PM
Very excited to see our study published today, joint effort with @benmpeter.bsky.social group, co-led by @leonardoiasi.bsky.social & Manjusha Chintalapati. Excitedly, @arevsumer.bsky.social et al. in Nature today show similar timeline of N gene flow. Details👇