Molly Przeworski
@mollyprz.bsky.social
Population & Human Genetics
Pinned
SAVE THE DATE: the yearly NY Population Genetics meeting will be back on March 9 2026, generously hosted by the
@simonsfoundation.org. Details to follow. Please RT.
@simonsfoundation.org. Details to follow. Please RT.
Reposted by Molly Przeworski
Excited to share a preprint of my PhD project looking at interactions between SNPs and polygenic scores in the UK Biobank!
A thread... 🧵
www.medrxiv.org/content/10.1...
A thread... 🧵
www.medrxiv.org/content/10.1...
Interactions with polygenic background impact quantitative traits in the UK Biobank
Association studies have linked many genetic variants to a variety of phenotypes but under-standing the biological mechanisms underlying these signals remains a major challenge. Since genes operate wi...
www.medrxiv.org
November 24, 2025 at 5:13 PM
Excited to share a preprint of my PhD project looking at interactions between SNPs and polygenic scores in the UK Biobank!
A thread... 🧵
www.medrxiv.org/content/10.1...
A thread... 🧵
www.medrxiv.org/content/10.1...
Reposted by Molly Przeworski
Interactions with polygenic background impact quantitative traits in the UK Biobank https://www.medrxiv.org/content/10.1101/2025.11.14.25340263v1
November 18, 2025 at 5:40 AM
Interactions with polygenic background impact quantitative traits in the UK Biobank https://www.medrxiv.org/content/10.1101/2025.11.14.25340263v1
Reposted by Molly Przeworski
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 21, 2025 at 10:34 PM
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
Reposted by Molly Przeworski
My center at NYU SoM is hiring an Assistant/Associate Professor in human genetics and genomics. It's a wonderful place to do science. Please apply or pass along. apply.interfolio.com/177375
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
November 14, 2025 at 3:51 PM
My center at NYU SoM is hiring an Assistant/Associate Professor in human genetics and genomics. It's a wonderful place to do science. Please apply or pass along. apply.interfolio.com/177375
Reposted by Molly Przeworski
Congratulations to Joe Felsenstein on being awarded the 2026 Mendel Medal!
November 14, 2025 at 12:41 PM
Congratulations to Joe Felsenstein on being awarded the 2026 Mendel Medal!
Reposted by Molly Przeworski
Congratulations to Richard Durbin on being awarded our Genetics Society Medal!
November 14, 2025 at 12:40 PM
Congratulations to Richard Durbin on being awarded our Genetics Society Medal!
Reposted by Molly Przeworski
"What James Watson got wrong about DNA"
By the great Sohini Ramachandran (@sramach.bsky.social) and your boy for The Boston Globe (@bostonglobe.com).
www.bostonglobe.com/2025/11/14/o...
By the great Sohini Ramachandran (@sramach.bsky.social) and your boy for The Boston Globe (@bostonglobe.com).
www.bostonglobe.com/2025/11/14/o...
What James Watson got wrong about DNA - The Boston Globe
The science he helped pioneer consistently undermines his view that genes determine everything about us.
www.bostonglobe.com
November 14, 2025 at 4:50 PM
"What James Watson got wrong about DNA"
By the great Sohini Ramachandran (@sramach.bsky.social) and your boy for The Boston Globe (@bostonglobe.com).
www.bostonglobe.com/2025/11/14/o...
By the great Sohini Ramachandran (@sramach.bsky.social) and your boy for The Boston Globe (@bostonglobe.com).
www.bostonglobe.com/2025/11/14/o...
SAVE THE DATE: the yearly NY Population Genetics meeting will be back on March 9 2026, generously hosted by the
@simonsfoundation.org. Details to follow. Please RT.
@simonsfoundation.org. Details to follow. Please RT.
November 14, 2025 at 5:05 PM
SAVE THE DATE: the yearly NY Population Genetics meeting will be back on March 9 2026, generously hosted by the
@simonsfoundation.org. Details to follow. Please RT.
@simonsfoundation.org. Details to follow. Please RT.
Reposted by Molly Przeworski
Exciting new study led by @ekerdoncuff.bsky.social and @meaghanmarohn.bsky.social on the evolution of Lactase Persistence in South Asia.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Revisiting the Evolution of Lactase Persistence: Insights from South Asian Genomes
Lactase persistence (LP), the ability to digest lactose from milk into adulthood, is a classic example of natural selection in humans. Multiple mutations upstream of the LCT gene are associated with L...
www.biorxiv.org
November 7, 2025 at 2:33 PM
Exciting new study led by @ekerdoncuff.bsky.social and @meaghanmarohn.bsky.social on the evolution of Lactase Persistence in South Asia.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Molly Przeworski
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
U.S. Congress considers sweeping ban on Chinese collaborations
Researchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students
www.science.org
November 14, 2025 at 1:03 AM
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
Reposted by Molly Przeworski
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A
Insertion of an invading retrovirus regulates a novel color trait in swordtail fish
For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...
shorturl.at
November 12, 2025 at 8:34 PM
I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A
Reposted by Molly Przeworski
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.
www.cam.ac.uk/jobs/faculty...
www.cam.ac.uk/jobs/faculty...
Faculty Position in Computational Biology
Applications are invited for an Assistant/ Associate Professorship in Computational Biology to commence on 1 April 2026 or shortly thereafter. This is a joint post between the Department of Applied
www.cam.ac.uk
November 11, 2025 at 9:05 PM
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.
www.cam.ac.uk/jobs/faculty...
www.cam.ac.uk/jobs/faculty...
An empirical approach to evaluating the prevalence of long-lived balancing selection in humans--and important limitations. Work by @hannahmm.bsky.social
November 11, 2025 at 7:14 PM
An empirical approach to evaluating the prevalence of long-lived balancing selection in humans--and important limitations. Work by @hannahmm.bsky.social
Reposted by Molly Przeworski
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Reposted by Molly Przeworski
Very excited for our paper in @nature.com on what genes association studies discover and why. It was a privilege to work closely with @jeffspence.github.io, @jkpritch.bsky.social, and our collaborators.
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Specificity, length and luck drive gene rankings in association studies - Nature
Genetic association tests prioritize candidate genes based on different criteria.
www.nature.com
November 7, 2025 at 6:33 PM
Very excited for our paper in @nature.com on what genes association studies discover and why. It was a privilege to work closely with @jeffspence.github.io, @jkpritch.bsky.social, and our collaborators.
Reposted by Molly Przeworski
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Specificity, length and luck drive gene rankings in association studies - Nature
Genetic association tests prioritize candidate genes based on different criteria.
www.nature.com
November 7, 2025 at 12:05 AM
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Reposted by Molly Przeworski
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
November 5, 2025 at 10:59 AM
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
Reposted by Molly Przeworski
The exciting next instalment of Mutations in Time and Space... Open for registration now
Explore the origins, patterns and consequences of mutations across biological systems! #MITS26
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
🗓️ Conference dates: 13-15 April 2026
Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬
Check out our exciting speakers ➡️ bit.ly/4hmbnyr
#Genomics
November 4, 2025 at 10:28 AM
The exciting next instalment of Mutations in Time and Space... Open for registration now
Reposted by Molly Przeworski
We have TWO post-doctoral fellowships in the Biodiversity Centre at UBC next year! Am happy to chat if you might want to be hosted in my lab. biodiversity.ubc.ca/training-and... Deadline January 15th!
November 3, 2025 at 5:16 PM
We have TWO post-doctoral fellowships in the Biodiversity Centre at UBC next year! Am happy to chat if you might want to be hosted in my lab. biodiversity.ubc.ca/training-and... Deadline January 15th!
Reposted by Molly Przeworski
We are now accepting apps for our Simons Postdoctoral Fellowships in Plant Biology awards. Deadline is 12/4/2025: https://www.simonsfoundation.org/applications-for-simons-postdoctoral-fellowships-in-plant-biology-now-open/ #lifesciences
Applications for Simons Postdoctoral Fellowships in Plant Biology Now Open
Applications for Simons Postdoctoral Fellowships in Plant Biology Now Open on Simons Foundation
www.simonsfoundation.org
October 14, 2025 at 2:16 PM
We are now accepting apps for our Simons Postdoctoral Fellowships in Plant Biology awards. Deadline is 12/4/2025: https://www.simonsfoundation.org/applications-for-simons-postdoctoral-fellowships-in-plant-biology-now-open/ #lifesciences
Reposted by Molly Przeworski
I started a new job in Montpellier, France!
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
We left the US and moved to France
Hello readers, I got big updates! Some of you already know this, but it’s getting more real and more official every month: my family and I have left the US and moved to France! A few months ago I q…
abetterscientist.wordpress.com
October 27, 2025 at 7:19 PM
I started a new job in Montpellier, France!
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
Happy about new opportunities, sad about the state of things in the US.
abetterscientist.wordpress.com/2025/10/26/w...
Reposted by Molly Przeworski
The question isn’t "why does Signal use AWS?" It’s to look at the infrastructural requirements of any global, real-time, mass comms platform and ask how it is that we got to a place where there’s no realistic alternative to AWS and the other hyperscalers. 3/
October 27, 2025 at 10:38 AM
The question isn’t "why does Signal use AWS?" It’s to look at the infrastructural requirements of any global, real-time, mass comms platform and ask how it is that we got to a place where there’s no realistic alternative to AWS and the other hyperscalers. 3/
Reposted by Molly Przeworski
Amazing job opportunity at the @institutimagine.bsky.social, Head of the Genomics Platform.
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
October 23, 2025 at 7:14 PM
Amazing job opportunity at the @institutimagine.bsky.social, Head of the Genomics Platform.
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
I am adding an English translation of the opportunity, but fluency in French is a (reasonable) requirement for the position. Application link below.
www.welcometothejungle.com/fr/companies...
Reposted by Molly Przeworski
Results I'm sad to share but must be told - branching coral are now functionally extinct in Florida - to learn more check out the full study www.science.org/doi/10.1126/... and our personal summary theconversation.com/2-iconic-cor...
Heat-driven functional extinction of Caribbean Acropora corals from Florida’s Coral Reef
In 2023, a record-setting marine heat wave triggered the ninth mass coral bleaching event on Florida’s Coral Reef (FCR). We examined spatial patterns of heat exposure along the ~560-kilometer length o...
www.science.org
October 23, 2025 at 6:26 PM
Results I'm sad to share but must be told - branching coral are now functionally extinct in Florida - to learn more check out the full study www.science.org/doi/10.1126/... and our personal summary theconversation.com/2-iconic-cor...
Reposted by Molly Przeworski
We're launching a portal to review federal immigration enforcement in New York after yesterday’s ICE raid on Canal Street.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.
Federal Action Reporting Form
Federal Action Reporting Form Please use this form to share information regarding federal government action in New York state. Filing a complaint does not start
ag.ny.gov
October 22, 2025 at 6:48 PM
We're launching a portal to review federal immigration enforcement in New York after yesterday’s ICE raid on Canal Street.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.
New Yorkers who were present should submit videos or photos, and we will review and investigate any violations of the law.