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Roland Hatzenpichler

@environmicrobio.bsky.social

1.3K followers 95 following 1.4K posts

archaea, methane, single cell physiology, single cell activity, next generation physiology / for evidence-based decision-making / I hold strong opinions / I don’t mince words / posts reflect personal views / www.environmental-microbiology.com

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Roland Hatzenpichler @environmicrobio.bsky.social · Nov 21

Physiology, the functioning of a cell at a given time and in a given set of physiochemical conditions, is an emergent property that cannot be reliably predicted from genomic data or metabolic reconstructions alone. #testthy(metagenomic)hypotheses

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Roland Hatzenpichler @environmicrobio.bsky.social · 5h

Wird sie auch nicht, das steht lange vorher fest. Ausserdem warum wuerde man den Preis geben nur weil ein Zettel unterschrieben wurde. Es kann gut sein dass Israel am Samstag schon wieder bombadiert oder die Hamas Geiseln erschiest.

Roland Hatzenpichler @environmicrobio.bsky.social · 5h

Das ist seit Kissinger so.

Roland Hatzenpichler @environmicrobio.bsky.social · 5h

Ich stimme ihnen ja zu. Aber hier mal drei Beispiele wer den Friedensnobelpreis auch bekommen hat: Arafat, ein Terrorist. Kissinger, einer der groessten Kriegstreiber des 20sten Jahrhunderts. Obama, "wos wor jetzt mei Leistung". Den Preis kann keiner Ernst nehmen.

Roland Hatzenpichler @environmicrobio.bsky.social · 15h

Was wikipedia sagt: “Novoselov was the youngest Nobel laureate in physics since Brian Josephson in 1973, and in any field since Rigoberta Menchú (Peace) in 1992.”

Roland Hatzenpichler @environmicrobio.bsky.social · 15h

Ausnahmen bestätigen die Regel ;) Konstantin Novoselov war 35 als er 2010 den Nobelpreis fuer seine Graphen Experimente bekam.

Roland Hatzenpichler @environmicrobio.bsky.social · 1d

Congrats Julie!

Reposted by Roland Hatzenpichler

Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 1d

🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social [email protected] trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...

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Reposted by Roland Hatzenpichler

Ákos T Kovács @evolvedbiofilm.bsky.social · 1d

Half of microbial eukaryote literature focuses on only twelve human parasites

-in #ISMEJournal by Joanna Lepper, @hbrappap.bsky.social and @oliverio.bsky.social

academic.oup.com/ismej/advanc...

Half of microbial eukaryote literature focuses on only twelve human parasites

Abstract. Although microbial eukaryotes comprise the majority of eukaryotic phylogenetic diversity and inhabit nearly all ecosystems globally, most researc

academic.oup.com

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Reposted by Roland Hatzenpichler

Nagissa Mahmoudi @nagissa.bsky.social · 2d

Interested in life’s co-evolution with planetary environments?
🌎🦠🧪

I'm looking for a postdoc to join my group at #McGill and happy to sponsor applicants for the TSI fellowship.

Please reach out if interested!

academicjobsonline.org/ajo/jobs/30777

McGill University, Trottier Space Institute

Job #AJO30777, Trottier Space Institute Postdoctoral Fellow, Trottier Space Institute, McGill University, Montreal, Quebec, CA

academicjobsonline.org

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Roland Hatzenpichler @environmicrobio.bsky.social · 6d

The DOE has cancelled 321 awards, all in blue states, worth 7.5B$. www.latitudemedia.com/news/scoop-t...

SCOOP: These are the 321 awards DOE is canceling

All of the awards, totaling $7.5 billion, are for projects in blue states.

www.latitudemedia.com

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Reposted by Roland Hatzenpichler

cryoEM papers @cryoempapers.bsky.social · 20d

Correlative MS Imaging for cellular identification and analysis of in situ cryo-ET www.biorxiv.org/content/10.1101/2025.09.16.676641v1 #cryoem

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Reposted by Roland Hatzenpichler

Madhu Pai, MD, PhD @madhupai.bsky.social · 7d

PubMed is in trouble

This is beyond bad for medical research

pubmed.ncbi.nlm.nih.gov

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Roland Hatzenpichler @environmicrobio.bsky.social · 7d

Obwohl natürlich auch mal ein blindes Hund ein Korn finden kann gehe ich grundsätzlich davon aus, dass alles wogegen die FPOe wettert zu befürworten ist. Und in der Regel, je lautet sie kreischt, desto Unterstützung würdiger.

Roland Hatzenpichler @environmicrobio.bsky.social · 8d

Oh it is. It was more tongue in cheek. But I do think arguments can be made for a two domain tree of life :)

Roland Hatzenpichler @environmicrobio.bsky.social · 8d

According to this sheet red blood cells are prokaryotes because they lack a nucleus.

Roland Hatzenpichler @environmicrobio.bsky.social · 8d

Wish I could be there for archaea specific meetings ;(

Roland Hatzenpichler @environmicrobio.bsky.social · 8d

Second domain? Eukarya no more?!

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

I said it before and say it again. For every person who does metagenomics, we need 100 people who are doing the experimental work to test all the hypotheses raised by genomics.

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

I agree, there’s enough metagenomics data around to keep experimentalists busy for the next hundred years or more ;)

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

They'd pay a company to sequence and withhold the data from NCBI as long as possible. So I think your example is mostly theoretical.

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

I am not saying that the latter example is theoretically impossible but I assume that a person who doesn't want people to have access to "their" data wouldn't put them on a server before publication and they wouldn't work with a public sequencing center like JGI in the 1st place.

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

I am not saying that the latter example is theoretically possible but I assume that a person who doesn't want people to have access to "their" data wouldn't put them on a server or work with JGI in the 1st place. They'd pay a company to sequence and withold it from NCBI as long as possible.

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

As I said before in this thread, there's no way to enforce it. More importantly, we ask for contacting the creators ONLY if the dataset has no associated publication. Personally, I think this should just be common courtesy. I don't see it as a problem to ask if my analyses would scoop another person

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

Why do you think this creates a gatekeeping problem?

Roland Hatzenpichler @environmicrobio.bsky.social · 9d

Even if this would be mainly a JGI problem, which is it is not, the fact is that a lot of sequencing data these days is generated by them. And because everyone in the world can use their sequencing facilities Everyone is affected.