Melanie Tschiersch
@mtschiersch.bsky.social
Computational Neuroscience PhD student in Barcelona. Working on Data Analysis of behavior and neural recordings and computational modeling of interhemispheric working memory
Pinned
Redundant, weakly connected prefrontal hemispheres balance precision and capacity in spatial working memory https://www.biorxiv.org/content/10.1101/2025.01.15.633176v1
🚨Excited to share my first @biorxivpreprint.bsky.social🚨 with the amazing Smith lab, @jbarbosa.org and Albert Compte who made this work possible.
We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵
We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵
Reposted by Melanie Tschiersch
Fresh out: a short review article where I give an overview of different ways that across-trial temporal structure is helpful in understanding cognitive models of decision-making
osf.io/preprints/ps...
osf.io/preprints/ps...
December 11, 2024 at 1:25 PM
Fresh out: a short review article where I give an overview of different ways that across-trial temporal structure is helpful in understanding cognitive models of decision-making
osf.io/preprints/ps...
osf.io/preprints/ps...
Reposted by Melanie Tschiersch
For everyone voting in Germany this Sunday: Check out this thread to learn about the different political parties' positions on science communication
#Wisskomm auf dem Wahlzettel? Wir haben die Parteien gefragt, welche Maßnahmen sie planen. Die Antworten zeigen unterschiedliche Schwerpunkte - von der langfristigen Finanzierung bis zur Anerkennung als Karrierebaustein.
Ein Überblick im Thread: 🧵👇
Ein Überblick im Thread: 🧵👇
a cartoon drawing of an envelope with the word vote on it
Alt: a cartoon drawing of an envelope with the word vote on it
media.tenor.com
February 18, 2025 at 2:49 PM
For everyone voting in Germany this Sunday: Check out this thread to learn about the different political parties' positions on science communication
Reposted by Melanie Tschiersch
UPDATE: It's happening now. German police entered the new venue to break up our meeting with Francesca Albanese and Amnesty International. The miss no chance to prove that totalitarianism is back in Germany even before the AfD has won gvt
February 18, 2025 at 1:46 PM
UPDATE: It's happening now. German police entered the new venue to break up our meeting with Francesca Albanese and Amnesty International. The miss no chance to prove that totalitarianism is back in Germany even before the AfD has won gvt
Reposted by Melanie Tschiersch
Reposted by Melanie Tschiersch
This Cybertruck did not crash. It made a heartfelt and perhaps ill-advised gesture that, in the moment, might have been misinterpreted as a crash, but we should not rush to judgement.
January 22, 2025 at 12:15 AM
This Cybertruck did not crash. It made a heartfelt and perhaps ill-advised gesture that, in the moment, might have been misinterpreted as a crash, but we should not rush to judgement.
Thank you so much, Seán! It's been a long time in the making but finally getting somewhere!
January 21, 2025 at 11:05 AM
Thank you so much, Seán! It's been a long time in the making but finally getting somewhere!
Reposted by Melanie Tschiersch
Thanks to the yield of U arrays, we were able for the 1st time AFAIK to average across neurons (not trials) and see memory bumps on single trials. Look at this 😍
Not the focus of the work but it taps into an open debate on the neural mech. of WM cf @cconstan.bsky.social @earlkmiller.bsky.social
Not the focus of the work but it taps into an open debate on the neural mech. of WM cf @cconstan.bsky.social @earlkmiller.bsky.social
January 20, 2025 at 1:08 PM
Thanks to the yield of U arrays, we were able for the 1st time AFAIK to average across neurons (not trials) and see memory bumps on single trials. Look at this 😍
Not the focus of the work but it taps into an open debate on the neural mech. of WM cf @cconstan.bsky.social @earlkmiller.bsky.social
Not the focus of the work but it taps into an open debate on the neural mech. of WM cf @cconstan.bsky.social @earlkmiller.bsky.social
🗯️Taken together, this shows that prefrontal hemispheres can adjust to varying task demands with a simple underlying architecture!
If you're interested in more details, check out the preprint or send me a message!
Also a HUGE shout-out to everyone involved.It's been (and will continue) fun!🎉 END/🧵
If you're interested in more details, check out the preprint or send me a message!
Also a HUGE shout-out to everyone involved.It's been (and will continue) fun!🎉 END/🧵
January 20, 2025 at 12:10 PM
🗯️Taken together, this shows that prefrontal hemispheres can adjust to varying task demands with a simple underlying architecture!
If you're interested in more details, check out the preprint or send me a message!
Also a HUGE shout-out to everyone involved.It's been (and will continue) fun!🎉 END/🧵
If you're interested in more details, check out the preprint or send me a message!
Also a HUGE shout-out to everyone involved.It's been (and will continue) fun!🎉 END/🧵
Well... turns out REDUNDANT hemispheres can also replicate this effect!! So it seems that redundant, weakly connected hemispheres can provide increased precision (redundancy) when WM demands are low and increased capacity (weak connections) when WM demands are high. 7/🧵
a man is making a funny face while holding his finger to his head .
ALT: a man is making a funny face while holding his finger to his head .
media.tenor.com
January 20, 2025 at 12:10 PM
Well... turns out REDUNDANT hemispheres can also replicate this effect!! So it seems that redundant, weakly connected hemispheres can provide increased precision (redundancy) when WM demands are low and increased capacity (weak connections) when WM demands are high. 7/🧵
When inputs were slightly lateralized, the model showed that each hemisphere stores the stronger contra- over a weaker ipsilateral input when WM capacity is reached. Remember from 2/ where I said the bilateral field advantage was seen as evidence for non-redundant, independent hemispheres?? 6/🧵
January 20, 2025 at 12:10 PM
When inputs were slightly lateralized, the model showed that each hemisphere stores the stronger contra- over a weaker ipsilateral input when WM capacity is reached. Remember from 2/ where I said the bilateral field advantage was seen as evidence for non-redundant, independent hemispheres?? 6/🧵
This got us thinking: This model can represent the same memory redundantly, but also maintains history drift privately, allowing for private and shared memories. What does this mean when multiple items need to be remembered?🤔 5/🧵
January 20, 2025 at 12:10 PM
This got us thinking: This model can represent the same memory redundantly, but also maintains history drift privately, allowing for private and shared memories. What does this mean when multiple items need to be remembered?🤔 5/🧵
we modeled two redundant spiking bump attractor networks with inter-area connections and replicated the data if connections were tuned and weak. Furthermore, 🖥️model + 🐒data were in agreement that weak connections lead to private history attraction (serial dependence) in each hemisphere. 4/🧵
January 20, 2025 at 12:10 PM
we modeled two redundant spiking bump attractor networks with inter-area connections and replicated the data if connections were tuned and weak. Furthermore, 🖥️model + 🐒data were in agreement that weak connections lead to private history attraction (serial dependence) in each hemisphere. 4/🧵
We first found that both hemispheres stored (bump-like FR in the figure) and guided behavior for the full visual field suggesting redundant hemispheres. Additionally, neural traces were only weakly correlated across hemispheres suggesting weak coordination between hemispheres... 3/🧵
January 20, 2025 at 12:10 PM
We first found that both hemispheres stored (bump-like FR in the figure) and guided behavior for the full visual field suggesting redundant hemispheres. Additionally, neural traces were only weakly correlated across hemispheres suggesting weak coordination between hemispheres... 3/🧵
How do prefrontal hemispheres support continuous spatial WM when visual inputs come strongly lateralized?🤔
Previous studies suggest:
1️⃣ Independent hemispheres:Larger capacity across hemifields (bilateral field advantage)?
2️⃣ Redundant hemispheres:Unilateral opto-disruption doesn’t impair behavior?2/🧵
Previous studies suggest:
1️⃣ Independent hemispheres:Larger capacity across hemifields (bilateral field advantage)?
2️⃣ Redundant hemispheres:Unilateral opto-disruption doesn’t impair behavior?2/🧵
January 20, 2025 at 12:10 PM
How do prefrontal hemispheres support continuous spatial WM when visual inputs come strongly lateralized?🤔
Previous studies suggest:
1️⃣ Independent hemispheres:Larger capacity across hemifields (bilateral field advantage)?
2️⃣ Redundant hemispheres:Unilateral opto-disruption doesn’t impair behavior?2/🧵
Previous studies suggest:
1️⃣ Independent hemispheres:Larger capacity across hemifields (bilateral field advantage)?
2️⃣ Redundant hemispheres:Unilateral opto-disruption doesn’t impair behavior?2/🧵
🚨Excited to share my first @biorxivpreprint.bsky.social🚨 with the amazing Smith lab, @jbarbosa.org and Albert Compte who made this work possible.
We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵
We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵
Redundant, weakly connected prefrontal hemispheres balance precision and capacity in spatial working memory https://www.biorxiv.org/content/10.1101/2025.01.15.633176v1
January 20, 2025 at 12:10 PM
🚨Excited to share my first @biorxivpreprint.bsky.social🚨 with the amazing Smith lab, @jbarbosa.org and Albert Compte who made this work possible.
We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵
We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵
Reposted by Melanie Tschiersch
Redundant, weakly connected prefrontal hemispheres balance precision and capacity in spatial working memory https://www.biorxiv.org/content/10.1101/2025.01.15.633176v1
January 17, 2025 at 1:01 AM
Redundant, weakly connected prefrontal hemispheres balance precision and capacity in spatial working memory https://www.biorxiv.org/content/10.1101/2025.01.15.633176v1
Reposted by Melanie Tschiersch
Thrilled to share my first co-last author paper 🥹
Lead by the amazing @mtschiersch.bsky.social 👸, we investigate how both 🐒PFC interact during working memory. Her work sheds light into WM mechanisms by reconciling previous contradictions.
Tune in for 🐒WM, serial dependence and attractor models
Lead by the amazing @mtschiersch.bsky.social 👸, we investigate how both 🐒PFC interact during working memory. Her work sheds light into WM mechanisms by reconciling previous contradictions.
Tune in for 🐒WM, serial dependence and attractor models
Redundant, weakly connected prefrontal hemispheres balance precision and capacity in spatial working memory https://www.biorxiv.org/content/10.1101/2025.01.15.633176v1
January 19, 2025 at 3:49 PM
Thrilled to share my first co-last author paper 🥹
Lead by the amazing @mtschiersch.bsky.social 👸, we investigate how both 🐒PFC interact during working memory. Her work sheds light into WM mechanisms by reconciling previous contradictions.
Tune in for 🐒WM, serial dependence and attractor models
Lead by the amazing @mtschiersch.bsky.social 👸, we investigate how both 🐒PFC interact during working memory. Her work sheds light into WM mechanisms by reconciling previous contradictions.
Tune in for 🐒WM, serial dependence and attractor models
good luck! Tagesschau says they are sceptical it will even arrive at all... but fingers crossed!
January 20, 2025 at 9:57 AM
good luck! Tagesschau says they are sceptical it will even arrive at all... but fingers crossed!
German's living abroad, we've got until the 2nd of February to register for the elections but it might still be tight that our votes count in the end. Anyways... better safe than sorry, so register at your last Meldestelle:)
January 16, 2025 at 1:19 PM
German's living abroad, we've got until the 2nd of February to register for the elections but it might still be tight that our votes count in the end. Anyways... better safe than sorry, so register at your last Meldestelle:)
Reposted by Melanie Tschiersch
Excited to share that today our paper recommender platform www.scholar-inbox.com has reached 20k users! We hope to reach 100k by the end of the year.. Lots of new features are being worked on currently and rolled out soon.
January 15, 2025 at 10:03 PM
Excited to share that today our paper recommender platform www.scholar-inbox.com has reached 20k users! We hope to reach 100k by the end of the year.. Lots of new features are being worked on currently and rolled out soon.
Reposted by Melanie Tschiersch
About 5 weeks between now and German parliamentary elections. And I'm seeing the exact same dynamics here that recently murdered what was left of US democracy.
3 things to watch out for:
1/5
3 things to watch out for:
1/5
January 16, 2025 at 9:27 AM
About 5 weeks between now and German parliamentary elections. And I'm seeing the exact same dynamics here that recently murdered what was left of US democracy.
3 things to watch out for:
1/5
3 things to watch out for:
1/5
Reposted by Melanie Tschiersch
Check our latest in which we leverage shape metrics to compare neural geometry across regions, sessions or subjects and how their differences predict behavior.
w/ Nejatbakhsh, Duong, @sarah-harvey.bsky.social, Brincat, @siegellab.bsky.social, @earlkmiller.bsky.social & @itsneuronal.bsky.social
w/ Nejatbakhsh, Duong, @sarah-harvey.bsky.social, Brincat, @siegellab.bsky.social, @earlkmiller.bsky.social & @itsneuronal.bsky.social
Quantifying Differences in Neural Population Activity With Shape Metrics https://www.biorxiv.org/content/10.1101/2025.01.10.632411v1
January 12, 2025 at 3:19 PM
Check our latest in which we leverage shape metrics to compare neural geometry across regions, sessions or subjects and how their differences predict behavior.
w/ Nejatbakhsh, Duong, @sarah-harvey.bsky.social, Brincat, @siegellab.bsky.social, @earlkmiller.bsky.social & @itsneuronal.bsky.social
w/ Nejatbakhsh, Duong, @sarah-harvey.bsky.social, Brincat, @siegellab.bsky.social, @earlkmiller.bsky.social & @itsneuronal.bsky.social
Reposted by Melanie Tschiersch
🌍 El 1% más rico devora “su parte” del planeta en solo 10 días
https://spanishrevolution.net/el-1-mas-rico-devora-su-parte-del-planeta-en-solo-10-dias
Un análisis sobre cómo el 1% más rico contribuye al colapso climático sin asumir las consecuencias, mientras el resto lucha por sobrevivir.
https://spanishrevolution.net/el-1-mas-rico-devora-su-parte-del-planeta-en-solo-10-dias
Un análisis sobre cómo el 1% más rico contribuye al colapso climático sin asumir las consecuencias, mientras el resto lucha por sobrevivir.
El 1% más rico devora "su parte" del planeta en solo 10 días
Mientras la mayoría lucha por sobrevivir, los más privilegiados aceleran el colapso climático sin pagar las consecuencias.
spanishrevolution.net
January 13, 2025 at 5:04 PM
🌍 El 1% más rico devora “su parte” del planeta en solo 10 días
https://spanishrevolution.net/el-1-mas-rico-devora-su-parte-del-planeta-en-solo-10-dias
Un análisis sobre cómo el 1% más rico contribuye al colapso climático sin asumir las consecuencias, mientras el resto lucha por sobrevivir.
https://spanishrevolution.net/el-1-mas-rico-devora-su-parte-del-planeta-en-solo-10-dias
Un análisis sobre cómo el 1% más rico contribuye al colapso climático sin asumir las consecuencias, mientras el resto lucha por sobrevivir.
Reposted by Melanie Tschiersch
Reposted by Melanie Tschiersch
Wow, just wow.
V different approach reveals numerous problems in Scientific Reports - cf deevybee.blogspot.com/2024/10/an-o...
I do hope @springernature.bsky.social will start to publish reviewer reports and editor info as we suggested
V different approach reveals numerous problems in Scientific Reports - cf deevybee.blogspot.com/2024/10/an-o...
I do hope @springernature.bsky.social will start to publish reviewer reports and editor info as we suggested
January 14, 2025 at 7:39 AM
Wow, just wow.
V different approach reveals numerous problems in Scientific Reports - cf deevybee.blogspot.com/2024/10/an-o...
I do hope @springernature.bsky.social will start to publish reviewer reports and editor info as we suggested
V different approach reveals numerous problems in Scientific Reports - cf deevybee.blogspot.com/2024/10/an-o...
I do hope @springernature.bsky.social will start to publish reviewer reports and editor info as we suggested