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Reposted by Neil O’Connell

Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 1d

youtu.be/_zephafiitk?...

What's the point of pain? | BBC Ideas

YouTube video by BBC Ideas

youtu.be

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Neil O’Connell @neiloconnell.bsky.social · 2d

Great to see the OPTIMETH framework for optimising clinical trials in CRPS, brilliantly led by Keith Smart from @ucddublin.bsky.social now out in @painreports.bsky.social

journals.lww.com/painrpts/ful...

@britishpainsoc.bsky.social @efic.bsky.social @iasp.bsky.social @iasp-mesisig.bsky.social

journals.lww.com

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Reposted by Neil O’Connell

Methods, Evidence Synthesis and Implementation SIG @iasp-mesisig.bsky.social · 4d

MESISIG is now on BlueSky. We've migrated who we follow 9as far as possible) from X but do please follow us back. We promise all things methodology and pain research!

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Sense about Science @senseaboutsci.bsky.social · 10d

Registration and reporting will become mandatory for all clinical trials next year. It's good to see many trial sponsors already delivering on this, but with clear @hralatest.bsky.social guidance, no excuse for anyone not to be transparent about results #AllTrials

www.hra.nhs.uk/planning-and...

Guidance on changes to the clinical trials regulations

www.hra.nhs.uk

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Neil O’Connell @neiloconnell.bsky.social · Sep 3

To do no harm, we must first “know harms”
Our new perspective piece on the
challenge of measuring and reporting adverse
events in interventions for pain is now available in @painthejournal.bsky.social dx.doi.org/10.1097/j.pa...
@iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social

To do no harm, we must first “know harms”. The challenge of ... : PAIN

An abstract is unavailable.

dx.doi.org

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Reposted by Neil O’Connell

Jack Wilkinson @jdwilko.bsky.social · Sep 5

www.medrxiv.org/content/10.1...

INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.

INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials

The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....

www.medrxiv.org

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Neil O’Connell @neiloconnell.bsky.social · Sep 3

To do no harm, we must first “know harms”
Our new perspective piece on the
challenge of measuring and reporting adverse
events in interventions for pain is now available in @painthejournal.bsky.social dx.doi.org/10.1097/j.pa...
@iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social

To do no harm, we must first “know harms”. The challenge of ... : PAIN

An abstract is unavailable.

dx.doi.org

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Reposted by Neil O’Connell

Peer Community In @peercommunityin.bsky.social · Aug 22

📣 Save the date for the 12th PCI webinar on September 18, 2025, at 4 PM CET!! Dorothy Bishop (@deevybee.bsky.social) will present "Editors matter: How negligent publishers subvert quality control in scientific publishing ". For more details and registration, visit:

PCI Webinar Series - Peer Community In

The PCI webinar series is a series of seminars on research practices, publication practices, evaluation, scientific integrity, meta-research, organised by Peer Community In

peercommunityin.org

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Neil O’Connell @neiloconnell.bsky.social · Aug 18

@efic.bsky.social @britishpainsoc.bsky.social @auspainsoc.bsky.social

Michael Ferraro @mcferraro.bsky.social · Aug 18

Out today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...

Ketamine and other NMDA receptor antagonists for chronic pain - Ferraro, MC - 2025 | Cochrane Library

Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.

doi.org

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Michael Ferraro @mcferraro.bsky.social · Aug 18

Out today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...

Ketamine and other NMDA receptor antagonists for chronic pain - Ferraro, MC - 2025 | Cochrane Library

Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.

doi.org

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Massi(e)h Moayedi — مسیح مویدی @massih.bsky.social · May 3

The ENTRUST-Pain Evidence (Entrust-PE) is an important initiative to ensure that pain science is of high quality.
Framework published in J Pain.
Endorsed by @iasp.bsky.social & @efic.bsky.social.

More here: m.entrust-pe.org

#pain

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The Journal of Pain @thejournalofpain.bsky.social · Jul 28

Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field.

Full: www.jpain.org/article/S152...

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eraneuron.bsky.social @eraneuron.bsky.social · Jul 31

Led by Prof. Neil O’Connell and funded by ERA-Net NEURON, ENTRUST-PE brought together an international network to co-create a new framework for trustworthy pain research.
Learn more: entrust-pe.org

#ENTRUSTPE #ChronicPain #ResearchIntegrity #EquityInResearch #PainResearch #NEURON #SuccessStory #RRI

ENTRUST-PE: A New Framework for Trustworthy Pain Research - ERA-NET NEURON

NEURON’s Role and Reflections from the First Networking Call The success of ENTRUST-PE also reflects the value of ERA-Net NEURON’s strategic focus on networking and community building. The Networking ...

www.neuron-eranet.eu

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JAMA @jama.com · Aug 10

📌 The SPIRIT 2025 statement updates the guidelines for randomized trial protocols to enhance their completeness, transparency, and consistency, benefiting stakeholders involved in clinical research.

ja.ma/4fzMVZS

Figure. SPIRIT 2025 Diagram of the Schedule of Enrollment, Interventions, and Assessments

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Reposted by Neil O’Connell

Nick Sheppard @nickshepp.bsky.social · Aug 6

Excellent, insightful conversation on the What the REF podcast between @simonhettrick.bsky.social and Marcus Munafo (@ukrepro.bsky.social) covering REF, open and transparent research and research culture (also rowing) youtu.be/uHRQjNqY6CY

Ep3. What the REF are our research incentives?

YouTube video by Hidden REF

youtu.be

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Neil O’Connell @neiloconnell.bsky.social · Jul 29

An expression of concern for an RCT 2 years after we raised concerns around the trustworthiness of the data. pubmed.ncbi.nlm.nih.gov/40709807/ this trial influences guidelines www.sciencedirect.com/science/arti...

EXPRESSION OF CONCERN: Group-Based Task-Oriented Exercises Aimed at Managing Kinesiophobia Improved Disability in Chronic Low Back Pain - PubMed

EXPRESSION OF CONCERN: Group-Based Task-Oriented Exercises Aimed at Managing Kinesiophobia Improved Disability in Chronic Low Back Pain

pubmed.ncbi.nlm.nih.gov

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Neil O’Connell @neiloconnell.bsky.social · Jul 29

Be angry

Meg Tirrell @megtirrell.bsky.social · Jul 29

A major NIH grant to study ways to restore hearing was terminated by the Trump administration bc it was awarded through a DEI initiative—to a researcher who qualified bc of his own hearing loss www.cnn.com/2025/07/29/h... @manorlaboratory.bsky.social

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Johannes Gierschner @gierschner.bsky.social · Jul 22

👉Predatory Conference Check List 👈

...based on my experience in detecting difficult cases, I did my own list for our group, as I was missing some points in those available... anyway, I'm happy to get suggestions etc.
#researchintegrity #PredatoryConference

download: www.uv.es/jogiers/pdf/...

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Reposted by Neil O’Connell

Pain Research Forum @painresforum.bsky.social · Jul 21

Have you wanted to understand what is meant by “trustworthy” research? Attend this #webinar TODAY to hear from @davidhosch.bsky.social, @neiloconnell.bsky.social, @jdwilko.bsky.social, @nadiasoliman.bsky.social, @lesleyuttley.bsky.social bit.ly/4kSQjjy

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Neil O’Connell @neiloconnell.bsky.social · Jul 21

Nice piece from Nadia Soliman and Michael Ferraro in MJA Insight on the state of the evidence for the management of neuropathic pain: insightplus.mja.com.au/2025/28/neur...

Neuropathic pain: our best treatments still fall short - InSight+

Despite a large body of new evidence, our best treatments for neuropathic pain continue to provide only modest benefits. Neuropathic pain is a common and disabling condition caused by injury or diseas...

insightplus.mja.com.au

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Neil O’Connell @neiloconnell.bsky.social · Jul 18

A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research
www.tandfonline.com/doi/full/10....

A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research

Published in Journal of Pain Research (Vol. 18, No. , 2025)

www.tandfonline.com

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Neil O’Connell @neiloconnell.bsky.social · Jul 16

Delighted that the editors of 15 Pain and Anaesthesiology have chosen to endorse and amplify the ENTRUST-PE framework. More info here: www.linkedin.com/pulse/entrus...

@iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social @ukrio.bsky.social @coarassessment.bsky.social

ENTRUST-PE: endorsement by senior editors of 15 Pain and Anaesthesiology Journals

We are beyond delighted that the ENTRUST-PE framework has been endorsed by the Editors in Chief of 15 International Pain and Anaesthesiology journals. Those editors are copublishing, across the journa...

www.linkedin.com

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Neil O’Connell @neiloconnell.bsky.social · Jul 15

Just a note - that link is broken.

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The Journal of Pain @thejournalofpain.bsky.social · Jul 14

Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field.

Full: doi.org/10.1016/j.jp...

Redirecting

doi.org

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PAIN @painthejournal.bsky.social · Jul 14

#PAIN joins with other editors of pain-related journals to affirm our editorial commitment to trust and integrity in science. Read our joint statement at bit.ly/4lj3b3b

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