Osteoarthritis and Cartilage Journal
@oacjournal.bsky.social
Osteoarthritis and Cartilage, and Osteoarthritis and Cartilage Open - official journals of OARSI. Impact factor 9.
http://www.oarsijournal.com
http://www.oarsijournal.com
How does MRI T2 mapping of articular cartilage in the knee serve as a biomarker for #OA?🧐
Harlianto et al. found in a population based cohort that T2 values were associated with BMI.
Read more: www.oarsijournal.com/article/S106...
Harlianto et al. found in a population based cohort that T2 values were associated with BMI.
Read more: www.oarsijournal.com/article/S106...
T2 mapping of the articular cartilage as a biomarker for knee osteoarthritis: An analysis of the population-based Rotterdam Study
Only few studies have investigated quantitative magnetic resonance imaging (MRI) T2
mapping of knee cartilage in population-based cohorts. Our objective was to evaluate
the association between T2 rela...
www.oarsijournal.com
February 19, 2026 at 3:03 AM
How does MRI T2 mapping of articular cartilage in the knee serve as a biomarker for #OA?🧐
Harlianto et al. found in a population based cohort that T2 values were associated with BMI.
Read more: www.oarsijournal.com/article/S106...
Harlianto et al. found in a population based cohort that T2 values were associated with BMI.
Read more: www.oarsijournal.com/article/S106...
OARSI is excited to announce that NOMINATIONS are open for Publication of the Year! 🤩
Research published in OAC and OAC Open since April 2025 are eligible for nomination!!!
Due March 6th!
Nominate here 🔗: form.jotform.com/223553406964157
Research published in OAC and OAC Open since April 2025 are eligible for nomination!!!
Due March 6th!
Nominate here 🔗: form.jotform.com/223553406964157
Journal Publication of the Year Nomination Form
Please click the link to complete this form.
form.jotform.com
February 14, 2026 at 4:41 PM
OARSI is excited to announce that NOMINATIONS are open for Publication of the Year! 🤩
Research published in OAC and OAC Open since April 2025 are eligible for nomination!!!
Due March 6th!
Nominate here 🔗: form.jotform.com/223553406964157
Research published in OAC and OAC Open since April 2025 are eligible for nomination!!!
Due March 6th!
Nominate here 🔗: form.jotform.com/223553406964157
🤔 Is there a relationship between osteoarthritis (OA)-induced neuroinflammation and neurodegenerative disorders?
👀 Read all about this interesting topic in this review by Prasoon et al - oarsijournal.com/article/S1063-…
👀 Read all about this interesting topic in this review by Prasoon et al - oarsijournal.com/article/S1063-…
February 11, 2026 at 6:58 AM
🤔 Is there a relationship between osteoarthritis (OA)-induced neuroinflammation and neurodegenerative disorders?
👀 Read all about this interesting topic in this review by Prasoon et al - oarsijournal.com/article/S1063-…
👀 Read all about this interesting topic in this review by Prasoon et al - oarsijournal.com/article/S1063-…
Does #unicompartmental or #bicompartmental joint space width measures reflect whole joint structural damage better?
www.oarsijournal.com/article/S106...
www.oarsijournal.com/article/S106...
Unicompartmental versus bicompartmental joint space width measures: Which reflect whole joint structural damage better? Data from IMI-APPROACH
To investigate the associations between whole joint cartilage and meniscal morphology
on MRI and radiographic joint space width (JSW) measures and in knee osteoarthritis
(KOA), to determine whether bi...
www.oarsijournal.com
February 10, 2026 at 9:47 AM
Does #unicompartmental or #bicompartmental joint space width measures reflect whole joint structural damage better?
www.oarsijournal.com/article/S106...
www.oarsijournal.com/article/S106...
The basic science #EditorsChoice for #Feb is this work by de Roy et al. Learn about the tribological impact of synovial fluid (SF) viscosity and composition during the different stages of #OA!
Read more📚: www.oarsijournal.com/article/S106...
Read more📚: www.oarsijournal.com/article/S106...
February 2, 2026 at 1:45 PM
The basic science #EditorsChoice for #Feb is this work by de Roy et al. Learn about the tribological impact of synovial fluid (SF) viscosity and composition during the different stages of #OA!
Read more📚: www.oarsijournal.com/article/S106...
Read more📚: www.oarsijournal.com/article/S106...
🏳️🌈 Sexual orientation and #OA
⏰ Feb's Editor's Choice by Sha et al. investigated the relationship between #sexualorientation and OA risk in LGBTQIA2S+ population
✅ They found a higher risk of OA in bisexual & lesbian women but a lower risk in gay men
oarsijournal.com/article/S106...
⏰ Feb's Editor's Choice by Sha et al. investigated the relationship between #sexualorientation and OA risk in LGBTQIA2S+ population
✅ They found a higher risk of OA in bisexual & lesbian women but a lower risk in gay men
oarsijournal.com/article/S106...
February 1, 2026 at 1:47 PM
🏳️🌈 Sexual orientation and #OA
⏰ Feb's Editor's Choice by Sha et al. investigated the relationship between #sexualorientation and OA risk in LGBTQIA2S+ population
✅ They found a higher risk of OA in bisexual & lesbian women but a lower risk in gay men
oarsijournal.com/article/S106...
⏰ Feb's Editor's Choice by Sha et al. investigated the relationship between #sexualorientation and OA risk in LGBTQIA2S+ population
✅ They found a higher risk of OA in bisexual & lesbian women but a lower risk in gay men
oarsijournal.com/article/S106...
This month in #OAC Hyodo et al. assessed the effects of imeglimin, a novel anti-diabetic agent related to metformin, on the development and progression of knee #OA.
Read more 📚: sciencedirect.com/science/arti...
Read more 📚: sciencedirect.com/science/arti...
January 30, 2026 at 4:50 PM
This month in #OAC Hyodo et al. assessed the effects of imeglimin, a novel anti-diabetic agent related to metformin, on the development and progression of knee #OA.
Read more 📚: sciencedirect.com/science/arti...
Read more 📚: sciencedirect.com/science/arti...
More #Basic #Science in #OAC this work by Simoes et al. develops a #translational strategy inhibiting aggrecanase activity in #OA using TIMP-3.
Learn more 🔗
sciencedirect.com/science/arti...
Learn more 🔗
sciencedirect.com/science/arti...
January 28, 2026 at 3:50 PM
More #Basic #Science in #OAC this work by Simoes et al. develops a #translational strategy inhibiting aggrecanase activity in #OA using TIMP-3.
Learn more 🔗
sciencedirect.com/science/arti...
Learn more 🔗
sciencedirect.com/science/arti...
New in #OAC, Xu et al. investigates parathyroid hormone-related peptide nuclear localization segment (PTHrP-NLS) and parathyroid hormone 1 receptor (PTH1R) signal-dependent rehabilitative effects of CD90+ chondrocytes on degenerative TMJ cartilage.
oarsijournal.com/article/S106...
oarsijournal.com/article/S106...
January 26, 2026 at 3:20 PM
New in #OAC, Xu et al. investigates parathyroid hormone-related peptide nuclear localization segment (PTHrP-NLS) and parathyroid hormone 1 receptor (PTH1R) signal-dependent rehabilitative effects of CD90+ chondrocytes on degenerative TMJ cartilage.
oarsijournal.com/article/S106...
oarsijournal.com/article/S106...
How do sex differences in the brainstem alter experimental #osteoarthritis ?🧐
Check out this work by Rodrigues et al.
www.sciencedirect.com/science/arti...
Check out this work by Rodrigues et al.
www.sciencedirect.com/science/arti...
January 23, 2026 at 4:27 PM
How do sex differences in the brainstem alter experimental #osteoarthritis ?🧐
Check out this work by Rodrigues et al.
www.sciencedirect.com/science/arti...
Check out this work by Rodrigues et al.
www.sciencedirect.com/science/arti...
Ziemian et al. demonstrates repetitive loading induced protective effects in the joint & attenuated OA progression over time relative to a single bout of loading even when applied at hyperphysiological load magnitudes known to initiate cartilage damage.
Read more🔗
pubmed.ncbi.nlm.nih.gov/40020990/
Read more🔗
pubmed.ncbi.nlm.nih.gov/40020990/
January 20, 2026 at 2:17 PM
Ziemian et al. demonstrates repetitive loading induced protective effects in the joint & attenuated OA progression over time relative to a single bout of loading even when applied at hyperphysiological load magnitudes known to initiate cartilage damage.
Read more🔗
pubmed.ncbi.nlm.nih.gov/40020990/
Read more🔗
pubmed.ncbi.nlm.nih.gov/40020990/
The January #EditorsChoice #Basic #Science in #OAC is this review by Wallace et al. Learn about the decreased risk of OA in non-industrialized societies.
Read more: www.sciencedirect.com/science/arti...
Read more: www.sciencedirect.com/science/arti...
January 12, 2026 at 2:27 PM
The January #EditorsChoice #Basic #Science in #OAC is this review by Wallace et al. Learn about the decreased risk of OA in non-industrialized societies.
Read more: www.sciencedirect.com/science/arti...
Read more: www.sciencedirect.com/science/arti...
As we usher in the new year, we also wanted to celebrate the achievements of a giant in the hashtag#osteoarthritis community.
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
January 12, 2026 at 1:19 AM
As we usher in the new year, we also wanted to celebrate the achievements of a giant in the hashtag#osteoarthritis community.
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
🔥 New year new issue!
2026's first editors choice is this large (n>500,000) cohort study on the effects of air pollution on osteoarthritis risk
Read more from Chen et al here: oarsijournal.com/article/S106...
#carbonmonoxide #nitrogendioxide #pm10
2026's first editors choice is this large (n>500,000) cohort study on the effects of air pollution on osteoarthritis risk
Read more from Chen et al here: oarsijournal.com/article/S106...
#carbonmonoxide #nitrogendioxide #pm10
January 7, 2026 at 1:41 PM
🔥 New year new issue!
2026's first editors choice is this large (n>500,000) cohort study on the effects of air pollution on osteoarthritis risk
Read more from Chen et al here: oarsijournal.com/article/S106...
#carbonmonoxide #nitrogendioxide #pm10
2026's first editors choice is this large (n>500,000) cohort study on the effects of air pollution on osteoarthritis risk
Read more from Chen et al here: oarsijournal.com/article/S106...
#carbonmonoxide #nitrogendioxide #pm10
#New in #OAC Work from Chen et al. found that treadmill #exercise offers protective effects when initiated early after OA onset but may worsen outcomes if delayed.🏃🏃♂️🏃♀️
🔗
oarsijournal.com/article/S106...
🔗
oarsijournal.com/article/S106...
December 29, 2025 at 9:09 PM
#New in #OAC Work from Chen et al. found that treadmill #exercise offers protective effects when initiated early after OA onset but may worsen outcomes if delayed.🏃🏃♂️🏃♀️
🔗
oarsijournal.com/article/S106...
🔗
oarsijournal.com/article/S106...
How does Estrogen receptor-α loss accelerate cartilage degradation? 🧐
#New in #OAC this month!
Read more:
www.oarsijournal.com/article/S106...
#New in #OAC this month!
Read more:
www.oarsijournal.com/article/S106...
December 29, 2025 at 1:06 AM
How does Estrogen receptor-α loss accelerate cartilage degradation? 🧐
#New in #OAC this month!
Read more:
www.oarsijournal.com/article/S106...
#New in #OAC this month!
Read more:
www.oarsijournal.com/article/S106...
#OAC #Dec TMJ condylar cartilage exhibits a distinct hyaline microstructure compared to knee cartilage, characterized by higher cell density, smaller cells, and enlarged cell lacunae filled with GAGs, contributing to a load-responsive mechanical behavior.
🔗 www.sciencedirect.com/science/arti...
🔗 www.sciencedirect.com/science/arti...
December 10, 2025 at 2:37 PM
#OAC #Dec TMJ condylar cartilage exhibits a distinct hyaline microstructure compared to knee cartilage, characterized by higher cell density, smaller cells, and enlarged cell lacunae filled with GAGs, contributing to a load-responsive mechanical behavior.
🔗 www.sciencedirect.com/science/arti...
🔗 www.sciencedirect.com/science/arti...
Where does OA pain really come from? 🤔
December's Editor's Choice (Clinical) suggests it's NOT just the cartilage
Targeting entheses might be next frontier for symptom relief
Read more from Ziegeler et al: www.oarsijournal.com/article/S106...
December's Editor's Choice (Clinical) suggests it's NOT just the cartilage
Targeting entheses might be next frontier for symptom relief
Read more from Ziegeler et al: www.oarsijournal.com/article/S106...
December 3, 2025 at 12:59 PM
Where does OA pain really come from? 🤔
December's Editor's Choice (Clinical) suggests it's NOT just the cartilage
Targeting entheses might be next frontier for symptom relief
Read more from Ziegeler et al: www.oarsijournal.com/article/S106...
December's Editor's Choice (Clinical) suggests it's NOT just the cartilage
Targeting entheses might be next frontier for symptom relief
Read more from Ziegeler et al: www.oarsijournal.com/article/S106...
#New in #OAC Xiao et al. investigates the role of CX3CR1⁺ macrophages and microglia in local inflammation and pain using transgenic mouse models and surgically induced disc herniation model.
🔗
sciencedirect.com/science/arti...
🔗
sciencedirect.com/science/arti...
November 29, 2025 at 4:22 PM
#New in #OAC Xiao et al. investigates the role of CX3CR1⁺ macrophages and microglia in local inflammation and pain using transgenic mouse models and surgically induced disc herniation model.
🔗
sciencedirect.com/science/arti...
🔗
sciencedirect.com/science/arti...
New in #OAC Alimy et al. identified subchondral bone endotypes with distinct clinical and cellular characteristics as a basis for developing novel OA therapies.
🔗
www.oarsijournal.com/article/S106...
🔗
www.oarsijournal.com/article/S106...
Multidimensional characterization and clinical profiling of subchondral bone endotypes in hip osteoarthritis
Treatment of osteoarthritis (OA) remains limited to symptom management and surgery
without addressing pathophysiological or individual patient-specific factors. Here,
we aimed to decipher whether indi...
www.oarsijournal.com
November 28, 2025 at 2:54 PM
New in #OAC Alimy et al. identified subchondral bone endotypes with distinct clinical and cellular characteristics as a basis for developing novel OA therapies.
🔗
www.oarsijournal.com/article/S106...
🔗
www.oarsijournal.com/article/S106...
This collaborative work from Farhat et al. seeks to learn about the brain-joint connection and reveals a CB1 dependent hypothalamic connection to the lateral meniscus that prevents its mineralization and subsequent articular cartilage damage.
🔗 www.oarsijournal.com/article/S106...
🔗 www.oarsijournal.com/article/S106...
November 24, 2025 at 4:41 PM
This collaborative work from Farhat et al. seeks to learn about the brain-joint connection and reveals a CB1 dependent hypothalamic connection to the lateral meniscus that prevents its mineralization and subsequent articular cartilage damage.
🔗 www.oarsijournal.com/article/S106...
🔗 www.oarsijournal.com/article/S106...
🆕 Editor's Choice!
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
November 14, 2025 at 3:19 PM
🆕 Editor's Choice!
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
LAST DAY TO SUBMIT!☺️
One week left to submit your #Cover #Art for the #OAC cover art competition. We look forward to seeing all of the creative designs. 🤩
Are you a creative scientist?🧐
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
November 10, 2025 at 12:49 PM
LAST DAY TO SUBMIT!☺️
How did Zhou et al. monitor the temporal profiling of lipid mediators in the synovium and tibial plateau during joint inflammation🧐? Learn out this work in this month's #EditorsChoice paper for #Basic #Science.
🔗
www.sciencedirect.com/science/arti...
🔗
www.sciencedirect.com/science/arti...
November 10, 2025 at 12:39 PM
How did Zhou et al. monitor the temporal profiling of lipid mediators in the synovium and tibial plateau during joint inflammation🧐? Learn out this work in this month's #EditorsChoice paper for #Basic #Science.
🔗
www.sciencedirect.com/science/arti...
🔗
www.sciencedirect.com/science/arti...
One week left to submit your #Cover #Art for the #OAC cover art competition. We look forward to seeing all of the creative designs. 🤩
Are you a creative scientist?🧐
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
November 3, 2025 at 1:56 PM