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Patrick Turley @paturley.bsky.social · 8d

I had to rescue Dad from Elko once while I was driving back Seattle because he had a major stomach flu and his carpool left him behind. Had to detour down a windy canyon in a blizzard with like 5 foot visibility and I'd start fish tailing any time I drove over 10 mph. Elko seemed nice enough though.

Reposted by Patrick Turley

Institute for Behavioral Genetics (IBG) @ibg.colorado.edu · 13d

University of Colorado Boulder Department of Psychology & Neuroscience is searching for TWO tenure track assistant professors. This is open to all department areas, including Behavioral, Psychiatric, and Statistical Genetics🧬 jobs.colorado.edu/jobs/JobDeta...

Assistant Professor

jobs.colorado.edu

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Patrick Turley @paturley.bsky.social · 19d

This is exactly what I argued for months. It's not sustainable! But the airport considerations won me over in the end.

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Patrick Turley @paturley.bsky.social · 19d

So annoying! This was ultimately the reason we hyphenated our kids' last names. Both their names have like 10 syllables now, but I'm less likely to get detained at an airport.

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Reposted by Patrick Turley

Robel Alemu @robel-alemu.bsky.social · 24d

Excited to share our preprint on PGI portability across ancestries—now on bioRxiv. With co-authors @aysuo.bsky.social, @paturley.bsky.social, @alextisyoung.bsky.social, and @Dan_J_Benjamin. Preprint: doi.org/10.1101/2025... Thread below for details.

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Patrick Turley @paturley.bsky.social · Sep 12

Essentially anything by Brandon Sanderson

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Patrick Turley @paturley.bsky.social · Sep 10

Wish I had seen this earlier...

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Reposted by Patrick Turley

James 🎃cello 🌉 @jamespirruccello.com · Sep 10

Settings -> Content and media -> uncheck 'autoplay videos and GIFs'

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Reposted by Patrick Turley

Shai Carmi @shaicarmi.bsky.social · Sep 10

Excited to present our new tool "PEStimate", an online app for predicting risk reductions after Polygenic Embryo Screening (PES).

Find the app here:
polygenicembryo.shinyapps.io/pestimate/

Preprint:
www.medrxiv.org/content/10.1...

PEStimate: Predicting offspring disease risk after Polygenic Embryo Screening

Motivation: Polygenic embryo screening (PES) is a new technology in reproductive medicine, whereby human in-vitro fertilization embryos are screened for their genetic risk of complex, polygenic diseas...

www.medrxiv.org

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Reposted by Patrick Turley

Ted Schwaba @tedmond.bsky.social · Sep 2

I'm looking for a PhD student to do some trailblazing at the frontier of personality genomics and lifespan gene-environment transactions (start Fall 2026)! If you want to work with me: psychology.msu.edu/graduatestud...
(PS @drmeltemyucel.bsky.social is taking a student too, in moral psych/dev!)

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Patrick Turley @paturley.bsky.social · Aug 10

Great thread! We make this point in the NEJM paper, but I think it flew under the radar for many.

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Patrick Turley @paturley.bsky.social · Aug 1

I think I ultimately disagree too, but I thought it was thought provoking. Like the case where maybe a parent is asked to share their DNA and they explicitly say they don't consent. Genotyping a sibling and then imputing their DNA may be legal, but it feels icky, no?

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Reposted by Patrick Turley

Margot van de Weijer @margotvdweijer.bsky.social · Aug 1

New pre-print online: Imputing parental genotypes through Mendelian Imputation: Ethical and Legal Considerations
osf.io/preprints/ps...

OSF

osf.io

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Patrick Turley @paturley.bsky.social · May 28

The CCT paper has a discussion of why you should use the conventional bw even with the correction due to coverage maybe, but I'm lost. I'm getting pretty close to a 5% T1 error rate even when I use the larger bw. Has anyone smarter than me thought through this and can tell me what I'm missing?

Patrick Turley @paturley.bsky.social · May 28

I ran a few quick simulations with quartic trends and local linear regression, but used bw's at different multiples of the CCT bw. As expected, using uncorrected estimates, the MSE is minimized at the CCT bw, but the bias-corrected estimate's MSE is minimized at a 2-3 times larger bw.

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Patrick Turley @paturley.bsky.social · May 28

RD optimal bw question: The CCT approach in rdrobust minimizes the MSE assuming you use local polynomial trends. Then it does a bias correction, which reduces the bias but increases the SEs. But then doesn't that mean that the new estimate no longer minimizes the MSE? #econsky

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Reposted by Patrick Turley

Aysu Okbay @aysuo.bsky.social · May 20

PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social

bioRxivpreprint @biorxivpreprint.bsky.social · May 19

An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference https://www.biorxiv.org/content/10.1101/2025.05.14.653986v1

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Patrick Turley @paturley.bsky.social · May 5

I am unreasonably proud of this joke, but I'm worried that no one will get it... simple.wikipedia.org/wiki/Tau_(ma...

"No, no, Patrick. We all got it. It just wasn't very funny," you all reply.

Tau (mathematical constant) - Simple English Wikipedia, the free encyclopedia

simple.wikipedia.org

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Patrick Turley @paturley.bsky.social · May 5

The Life of Tau

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Reposted by Patrick Turley

Alex Strudwick Young @alextisyoung.bsky.social · Apr 28

I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply: recruit.apo.ucla.edu/JPF10275. Please repost!

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Patrick Turley @paturley.bsky.social · Apr 8

"Complete the USC Sustainability Survey, and you’ll have the chance to win a $50 USC Bookstore e-gift card. Keck Medicine of USC employees also have an opportunity to win one of two e-bikes!" Why do I feel like the monkey who got the cucumber...?

a panda bear is sitting in a cage looking out of the window .

ALT: a panda bear is sitting in a cage looking out of the window .

media.tenor.com

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Patrick Turley @paturley.bsky.social · Apr 7

I feel like you lied to me a couple months ago... (Mine vomited down the front of my shirt during the 5am bottle this morning.)
bsky.app/profile/elim...

Eli McCann @elimccann.bsky.social · Jan 9

In the first month it felt like we were changing outfits constantly but then the vomit slowed down significantly so he can pretty easily make it a whole day in one outfit now.

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Reposted by Patrick Turley

Jenn Dowd @drjenndowd.bsky.social · Mar 28

Cool new work using changes in compulsory schooling laws & data from @ukbiobank.bsky.social by @paturley.bsky.social & colleagues:

Additional time spent in education reduces Alzheimer's risk:

www.nber.org/bh/20251/add... #econsky #episky

Figure showing that people who stayed in education longer due to education reforms had lower risk of Alzheimer's later in life.

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Patrick Turley @paturley.bsky.social · Mar 28

Thanks, Jenn!

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Reposted by Patrick Turley

Eric Turkheimer @ent3c.bsky.social · Mar 26

Very nice piece about "race science" and its implications in @undark.org. Nice and clear on the consensus issues (so-called race science is scientifically invalid) and thoughtful on more difficult questions of what should be done about it in terms of academic freedom and open science.

In Genetics, a Tense Coexistence of Mainstream and Fringe Views

In an era of open data, genome-wide association studies have become entangled with efforts to prove Black inferiority.

undark.org

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