Cole Sitron
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pelletfraction.bsky.social
Cole Sitron
@pelletfraction.bsky.social
18 followers 56 following 11 posts
Cell biology enthusiast
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Reposted by Cole Sitron
asapresearch.parkinsonsroadmap.org
How does rapid, transparent sharing accelerate #Parkinsons research? 🧪

Kicking off our #OpenScienceWeek highlights, Cole Sitron, PhD (@pelletfraction.bsky.social) of CRN Team Harper, explains how Open Science lays the foundation for faster, more equitable discovery ⬇️

#ScienceForAll
A purple to blue gradient graphic highlighting Open Science’s role in promoting equity and accessibility in Parkinson’s disease research. It features a quote from Cole Sitron, PhD (CRN Team Harper), emphasizing that Open Science encourages a collaborative approach leading to faster discoveries. A headshot of Sitron, the ASAP logo, and an Open Science Star are also present. A purple to blue gradient graphic about Open Science’s role in Parkinson’s disease research that includes a quote from researcher Cole Sitron, PhD (CRN Team Harper), emphasizing the importance of open access to data to further discoveries. A headshot of Sitron, the ASAP logo, and an Open Science Star are also present.
September 16, 2025 at 4:16 PM
pelletfraction.bsky.social
Why are α-synuclein aggregates in Parkinson’s disease (PD) toxic at the cell biological level?

Our new study shows that α-syn fibrils hijack the ESCRT membrane repair system, triggering a feedback loop that worsens aggregation.

You can find it at: authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
September 10, 2025 at 7:07 PM
Reposted by Cole Sitron
asapresearch.parkinsonsroadmap.org
A new preprint from CRN Team Harper found that the depletion of ESCRT-III weakens membranes, allowing alpha-synuclein aggregates to spread and cause damage.

Authors: @harperlabhms.bsky.social
@harvardcellbio.bsky.social @pelletfraction.bsky.social

🔗 Check out the full #preprint: shorturl.at/69Ha6
A graphic with black text reading "New Preprint from Team Harper" centered on a white background, surrounded by a multi-colored border.
February 25, 2025 at 4:13 PM