Philipp Steen
@philippsteen.bsky.social
Physics PhD student in the JungmannLab (MPI_Biochem / LMU_Muenchen / IMPRS_ML).
Pushing the limits of microscopy!
Pushing the limits of microscopy!
Excellent work, check it out!
I’m happy to share the main result of my PhD, which you can find on bioRxiv www.biorxiv.org/content/10.6.... If you are interested in learning about a new way to perform DNA-PAINT multiplexing, which we call Combi-PAINT, or if you are interested in the study of mRNA conformation, keep reading! 1/10
January 26, 2026 at 11:34 AM
Excellent work, check it out!
How do you scale super-resolution microscopy to dozens of proteins without linearly scaling imaging time?
We introduce Combi-PAINT: a combinatorial DNA-PAINT strategy that breaks the 1-target-per-round bottleneck of Exchange-PAINT: www.biorxiv.org/content/10.6...
1/5
We introduce Combi-PAINT: a combinatorial DNA-PAINT strategy that breaks the 1-target-per-round bottleneck of Exchange-PAINT: www.biorxiv.org/content/10.6...
1/5
www.biorxiv.org
January 26, 2026 at 9:34 AM
How do you scale super-resolution microscopy to dozens of proteins without linearly scaling imaging time?
We introduce Combi-PAINT: a combinatorial DNA-PAINT strategy that breaks the 1-target-per-round bottleneck of Exchange-PAINT: www.biorxiv.org/content/10.6...
1/5
We introduce Combi-PAINT: a combinatorial DNA-PAINT strategy that breaks the 1-target-per-round bottleneck of Exchange-PAINT: www.biorxiv.org/content/10.6...
1/5
Pretty images are one thing, but quantitative analysis of your super-resolution data is key! Check out our new paper where we introduce a method to investigate protein oligomerization and spatial patterns!
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution - Nature Communications
Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour ...
www.nature.com
May 8, 2025 at 5:30 AM
Pretty images are one thing, but quantitative analysis of your super-resolution data is key! Check out our new paper where we introduce a method to investigate protein oligomerization and spatial patterns!