Patryk Poliński
@ppolinski.bsky.social
Postdoc at @EMBLBarcelona. Working on unusual forms of splicing.
Great session by Sara Monaco introducing ReviewCommons at the EMBL international postdoc retreat! Insightful discussion on how transparent peer review can accelerate and improve publishing #OpenScience @embl.org @saramonaco-rc.bsky.social @embo.org
November 20, 2025 at 1:50 PM
Great session by Sara Monaco introducing ReviewCommons at the EMBL international postdoc retreat! Insightful discussion on how transparent peer review can accelerate and improve publishing #OpenScience @embl.org @saramonaco-rc.bsky.social @embo.org
Reposted by Patryk Poliński
Pre-print alert 🚨
We answer a longstanding question in the field. Do immune cells cause cerebral malaria?
The answer is YES!!!! And independently of P. falciparum accumulation in the brain.
www.biorxiv.org/cgi/content/...
We answer a longstanding question in the field. Do immune cells cause cerebral malaria?
The answer is YES!!!! And independently of P. falciparum accumulation in the brain.
www.biorxiv.org/cgi/content/...
Innate immune responses to Plasmodium falciparum disrupt the blood-brain barrier
Plasmodium falciparum accumulation at the blood-brain barrier (BBB) is a hallmark of cerebral malaria, a life-threatening complication. Conversely, the contribution of the immune response to vascular ...
www.biorxiv.org
October 21, 2025 at 11:06 AM
Pre-print alert 🚨
We answer a longstanding question in the field. Do immune cells cause cerebral malaria?
The answer is YES!!!! And independently of P. falciparum accumulation in the brain.
www.biorxiv.org/cgi/content/...
We answer a longstanding question in the field. Do immune cells cause cerebral malaria?
The answer is YES!!!! And independently of P. falciparum accumulation in the brain.
www.biorxiv.org/cgi/content/...
Reposted by Patryk Poliński
Dogs who experience neglect as puppies are more likely to be fearful and aggressive in adulthood, suggests research in Scientific Reports. go.nature.com/4pT9hKp 🧪
October 2, 2025 at 10:11 PM
Dogs who experience neglect as puppies are more likely to be fearful and aggressive in adulthood, suggests research in Scientific Reports. go.nature.com/4pT9hKp 🧪
Reposted by Patryk Poliński
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Staufen2 modulates the temporal dynamics of human neurogenesis in vitro
RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly u...
www.biorxiv.org
October 2, 2025 at 4:40 PM
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Patryk Poliński
Excited to welcome Eli Weinstein, DTU & ELLIS, to Collaboratorium Symposium Nov 10-11! His work on AI & causal biology is groundbreaking, advancing how we understand molecular systems and drug discovery.
Join us! #Collaboratorium2025 #AI #Biology
Join us! #Collaboratorium2025 #AI #Biology
October 2, 2025 at 12:27 PM
Excited to welcome Eli Weinstein, DTU & ELLIS, to Collaboratorium Symposium Nov 10-11! His work on AI & causal biology is groundbreaking, advancing how we understand molecular systems and drug discovery.
Join us! #Collaboratorium2025 #AI #Biology
Join us! #Collaboratorium2025 #AI #Biology
Reposted by Patryk Poliński
At EvoMG-DN we believe that evolutionary history shapes both the human genome and its pathogens and ultimately disease susceptibility.
We will tackle health challenges from an evolutionary perspective in the topic of: ageing, cancer and infectious diseases.
#PhD #EvolutionaryBiology #MSCA
We will tackle health challenges from an evolutionary perspective in the topic of: ageing, cancer and infectious diseases.
#PhD #EvolutionaryBiology #MSCA
September 30, 2025 at 11:22 AM
At EvoMG-DN we believe that evolutionary history shapes both the human genome and its pathogens and ultimately disease susceptibility.
We will tackle health challenges from an evolutionary perspective in the topic of: ageing, cancer and infectious diseases.
#PhD #EvolutionaryBiology #MSCA
We will tackle health challenges from an evolutionary perspective in the topic of: ageing, cancer and infectious diseases.
#PhD #EvolutionaryBiology #MSCA
Reposted by Patryk Poliński
📢 Join us at the Barcelona Collaboratorium on October 2, 2025!
Markus Deserno will present “On the thermodynamics of ternary asymmetric lipid membranes”.
A deep dive into the physics behind lipid rafts and membrane complexity.🧬
#Biophysics #BarcelonaCollaboratorium
Markus Deserno will present “On the thermodynamics of ternary asymmetric lipid membranes”.
A deep dive into the physics behind lipid rafts and membrane complexity.🧬
#Biophysics #BarcelonaCollaboratorium
September 26, 2025 at 9:56 AM
📢 Join us at the Barcelona Collaboratorium on October 2, 2025!
Markus Deserno will present “On the thermodynamics of ternary asymmetric lipid membranes”.
A deep dive into the physics behind lipid rafts and membrane complexity.🧬
#Biophysics #BarcelonaCollaboratorium
Markus Deserno will present “On the thermodynamics of ternary asymmetric lipid membranes”.
A deep dive into the physics behind lipid rafts and membrane complexity.🧬
#Biophysics #BarcelonaCollaboratorium
Reposted by Patryk Poliński
Have you ever wondered what happens with your microvessels after exposure to high temperature in fever? In this preprint former postdoc (ans soon to be PI) Viola Introini found that high temperatures cleaves glycocalyx , having severe consequences in malaria www.biorxiv.org/cgi/content/...
Febrile temperature enhances Plasmodium falciparum cytoadhesion by disrupting the endothelial glycocalyx
Fever, a universal host defense in infection and inflammation, paradoxically contributes to neurological complications in malaria. While febrile temperatures enhance the expression of parasite virulen...
www.biorxiv.org
September 9, 2025 at 8:02 AM
Have you ever wondered what happens with your microvessels after exposure to high temperature in fever? In this preprint former postdoc (ans soon to be PI) Viola Introini found that high temperatures cleaves glycocalyx , having severe consequences in malaria www.biorxiv.org/cgi/content/...
Reposted by Patryk Poliński
Time to accelerate! ⏱️4 weeks left to apply for EMBL ARISE2 fellowship programme.
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers
September 2, 2025 at 8:14 AM
Time to accelerate! ⏱️4 weeks left to apply for EMBL ARISE2 fellowship programme.
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers
Reposted by Patryk Poliński
Keystone symposia on stem-cell-based embryo models (SCBEMs). Join us in discussing the development, measurement, and manipulation of SCBEMs in California in Feb 2026!
www.keystonesymposia.org/conferences/...
Scholarship/ShortTalk Deadline: Oct 21
Early Registration Deadline: Dec 18 (Save $200!)
www.keystonesymposia.org/conferences/...
Scholarship/ShortTalk Deadline: Oct 21
Early Registration Deadline: Dec 18 (Save $200!)
Stem Cell Models in Embryology | Keystone Symposia
Join us at the Keystone Symposia on Stem Cell Models in Embryology, February 2026, in Pacific Grove, with field leaders!
www.keystonesymposia.org
August 18, 2025 at 2:17 PM
Keystone symposia on stem-cell-based embryo models (SCBEMs). Join us in discussing the development, measurement, and manipulation of SCBEMs in California in Feb 2026!
www.keystonesymposia.org/conferences/...
Scholarship/ShortTalk Deadline: Oct 21
Early Registration Deadline: Dec 18 (Save $200!)
www.keystonesymposia.org/conferences/...
Scholarship/ShortTalk Deadline: Oct 21
Early Registration Deadline: Dec 18 (Save $200!)
Reposted by Patryk Poliński
🚨🚨🚨
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
www.upf.edu
July 23, 2025 at 2:28 PM
🚨🚨🚨
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
Reposted by Patryk Poliński
Thanks to all co-authors and to everyone who supported this work - check it out!
Very happy to share the peer-reviewed version of our work on the cis-regulatory determinants of #microexon #splicing regulation by SRRM3/4, published in @natsmb.nature.com!
rdcu.be/ezGqT
Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu
rdcu.be/ezGqT
Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu
Core splicing architecture and early spliceosomal recognition determine microexon sensitivity to SRRM3/4
Nature Structural & Molecular Biology - Using massively parallel splicing assays and mathematical modeling, Bonnal et al. uncover that conserved splice site strength and exon length encode...
rdcu.be
August 11, 2025 at 7:01 AM
Thanks to all co-authors and to everyone who supported this work - check it out!
Reposted by Patryk Poliński
Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research. www.biorxiv.org/content/10.1...
July 11, 2025 at 7:31 PM
Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research. www.biorxiv.org/content/10.1...
Our latest in @cytoskeljournal.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
reveals how a tiny DAAM1 microexon controls actin dynamics & RHOA/ROCK signaling—now showing ARC protein levels expand this synaptic orchestra! 🧠⚡ @mirimiam.bsky.social , @crg.eu , @embl.org @prbb.org
onlinelibrary.wiley.com/doi/10.1002/...
reveals how a tiny DAAM1 microexon controls actin dynamics & RHOA/ROCK signaling—now showing ARC protein levels expand this synaptic orchestra! 🧠⚡ @mirimiam.bsky.social , @crg.eu , @embl.org @prbb.org
ARC Expands the DAAM1 Microexon‐Mediated Actin–RHOA/ROCK Interplay
Actin cytoskeleton and its dynamics play a crucial role in synaptic function, influencing dendritic spines' structural and functional plasticity. Recent findings unveiled the significance of alternat....
onlinelibrary.wiley.com
June 10, 2025 at 7:20 AM
Our latest in @cytoskeljournal.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
reveals how a tiny DAAM1 microexon controls actin dynamics & RHOA/ROCK signaling—now showing ARC protein levels expand this synaptic orchestra! 🧠⚡ @mirimiam.bsky.social , @crg.eu , @embl.org @prbb.org
onlinelibrary.wiley.com/doi/10.1002/...
reveals how a tiny DAAM1 microexon controls actin dynamics & RHOA/ROCK signaling—now showing ARC protein levels expand this synaptic orchestra! 🧠⚡ @mirimiam.bsky.social , @crg.eu , @embl.org @prbb.org
🚨Great podcast on our most recent work using
@notebooklmdeepdive.bsky.social on the role of microexon in DAAM1 in memory formation! 🧠🐁🔬🧫
🚨CLICK Here ➡️ drive.google.com/file/d/1elCs... ⬅️🚨
@mirimiam.bsky.social @maradierssen.bsky.social
@crg.eu @natcomms.nature.com @natureportfolio.nature.com
@notebooklmdeepdive.bsky.social on the role of microexon in DAAM1 in memory formation! 🧠🐁🔬🧫
🚨CLICK Here ➡️ drive.google.com/file/d/1elCs... ⬅️🚨
@mirimiam.bsky.social @maradierssen.bsky.social
@crg.eu @natcomms.nature.com @natureportfolio.nature.com
Neuronal Microexon Controls Memory Via Actin Dynamics.wav
drive.google.com
May 12, 2025 at 8:34 AM
🚨Great podcast on our most recent work using
@notebooklmdeepdive.bsky.social on the role of microexon in DAAM1 in memory formation! 🧠🐁🔬🧫
🚨CLICK Here ➡️ drive.google.com/file/d/1elCs... ⬅️🚨
@mirimiam.bsky.social @maradierssen.bsky.social
@crg.eu @natcomms.nature.com @natureportfolio.nature.com
@notebooklmdeepdive.bsky.social on the role of microexon in DAAM1 in memory formation! 🧠🐁🔬🧫
🚨CLICK Here ➡️ drive.google.com/file/d/1elCs... ⬅️🚨
@mirimiam.bsky.social @maradierssen.bsky.social
@crg.eu @natcomms.nature.com @natureportfolio.nature.com
Thrilled to share my 1st PhD paper exploring the role of a DAAM1 microexon in memory formation and learning! 🧠🐭💻🔬(and first post at @bsky.app :)
Finally published in
@natcomms.nature.com
nature.com/articles/s41... .
With @mirimiam.bsky.social, @maradierssen.bsky.social,
@crg.eu
Details below:
Finally published in
@natcomms.nature.com
nature.com/articles/s41... .
With @mirimiam.bsky.social, @maradierssen.bsky.social,
@crg.eu
Details below:
A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation - Nature Communications
Actin is crucial for nervous system function yet the role of microexons in its modulation is unclear. Here, the authors show that a microexon in DAAM1 has a role in actin dynamics, neuronal function a...
nature.com
May 9, 2025 at 9:35 AM
Thrilled to share my 1st PhD paper exploring the role of a DAAM1 microexon in memory formation and learning! 🧠🐭💻🔬(and first post at @bsky.app :)
Finally published in
@natcomms.nature.com
nature.com/articles/s41... .
With @mirimiam.bsky.social, @maradierssen.bsky.social,
@crg.eu
Details below:
Finally published in
@natcomms.nature.com
nature.com/articles/s41... .
With @mirimiam.bsky.social, @maradierssen.bsky.social,
@crg.eu
Details below: